Claus de la transició a l’Espai Europeu d’Educació Key factors in the transition to the European Higher Education Area Claves de la transición al Espacio Europeo de Educación Super... by Joan Mateo Andrés

“…In this paper, we examine the main factors that justified the efforts of the educational community, by analysing the most substantive aspects. We review the basic contents of the various ommuniqués and declarations and carry out a thorough analysis of future threats that could distort or disrupt the successful introduction of EHEA degrees.…”
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Histogram analysis based on DTI and NODDI for differentiating atypical high-grade glioma from primary central nervous system lymphoma by Shanshan Zhao, Shanshan Zhao, Xiaoyue Ma, Xiaoyue Ma, Linlin Li, Eryuan Gao, Eryuan Gao, Kai Zhao, Kai Zhao, Mengzhu Wang, Guang Yang, Hongbin Zheng, Jingliang Cheng, Jingliang Cheng, Guohua Zhao, Guohua Zhao

“…ODI75th within the enhancing tumor region showed the most favorable diagnostic performance.…”
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Polycyclic aromatic hydrocarbons in paddy soils: Distribution, source apportionment, and risk assessment in major rice-growing regions of China by Daoyu Liu, Lili Niu, Zili Guo, Shuduan Mao, Shuren Liu, Dongmei Xu, Chao Xu, Xiaohui Sun, Haiying Yu, Weiping Liu

“…Although 7 carcinogenic PAHs represented less than one-third of the total PAH concentrations, their toxic effects accounted for over 90 % of the overall toxicity, with cancer risks from daily rice consumption exceeding 60 %. Most samples showed PAH intake levels below permissible limits, and no samples posed unacceptable non-carcinogenic risk. …”
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Personalized adjuvant chemotherapy for stage II–III non-small cell lung cancer by E. O. Rodionov, S. V. Miller, M. M. Tsyganov, L. D. Zhuikova, L. V. Pikalova, O. V. Pankova, V. M. Perelmuter, D. V. Podolko, A. A. Mokh, O. A. Ananina, D. S. Pismenny, V. A. Markovich, D. M. Loos, N. V. Litvyakov

“…Special attention is paid to the feasibility of assessing the tumor sensitivity to certain chemotherapy drugs. Currently, the most studied predictors are monoresistance and multidrug resistance genes, such as ABCC5, RRM1, ERCC1, BRCA1, TOP1, TOP2a, TUBB3 and TYMS.The aim of the study was to analyze the outcomes of combined modality treatment using radical surgery and personalized adjuvant chemotherapy for stage II–III NSCLC.Material and Methods. …”
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Artificial intelligence-based personalised rituximab treatment protocol in membranous nephropathy (iRITUX): protocol for a multicentre randomised control trial by Céline Fernandez, Marion Cremoni, Laurent Bailly, Kevin Zorzi, Vesna Brglez, Barbara Seitz-Polski, Maxime Teisseyre, Alexandre Destere, Sylvain Benito

“…Introduction Membranous nephropathy is an autoimmune kidney disease and the most common cause of nephrotic syndrome in non-diabetic Caucasian adults. …”
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Standardized Classification of Infants With Robin Sequence Using MicroNAPS: The Impact of Syndromes and Comorbidities by Cory M. Resnick, MD, DMD, Jody E. Heffernan, RN, MSN, NNP-BC, Snigdha Jindal, MPH, Zaara Mehra, Irfan Ahmad, MD, Bimal Chaudhari, MD, MPH, Christopher Cielo, DO, Nicole Deptula, MD, Zarmina Ehsan, MD, Kelly N. Evans, MD, Semsa Gogcu, MD, MPH, Scott E. Hickey, MD, Jeffrey S. Marschall, DMD, MD, Maithilee Menezes, MD, David Molter, MD, Michael A. Padula, MD, Stacey L. Peterson-Carmichael, MD, Stephen Alex Rottgers, MD, Christopher M. Runyan, MD, PhD, Jordan W. Swanson, MD, Tara L. Wenger, MD, PhD, Andrew Deek, MD, DDS, on behalf of the Children’s Hospital Neonatal Consortium

“…We have compiled a comprehensive list of syndromes and comorbid diagnoses associated with RS and achieved expert consensus regarding the impact on early treatment decision-making for most. This list, assigned S scores, and a complete MicroNAPS calculator are publicly available at www.prscalculator.com.…”
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Improving Diet Quality of People Living With Obesity by Building Effective Dietetic Service Delivery Using Technology in a Primary Health Care Setting: Protocol for a Randomized Co... by Deborah A Kerr, Clare E Collins, Andrea Begley, Barbara Mullan, Satvinder S Dhaliwal, Claire E Pulker, Fengqing Zhu, Marie Fialkowski, Richard L Prince, Richard Norman, Anthony P James, Paul Aveyard, Helen Mitchell, Jacquie Garton-Smith, Megan E Rollo, Chloe Maxwell-Smith, Amira Hassan, Hayley Breare, Lucy M Butcher, Christina M Pollard

“… BackgroundAlmost a third of Australian adults are living with obesity, yet most cannot access medical nutrition therapy from dietitians, that is, the health professionals trained in dietary weight management services. …”
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Genome-wide identification and unveiling the role of MAP kinase cascade genes involved in sugarcane response to abiotic stressors by Ahmad Ali, Xue-Ting Zhao, Ji-Shan Lin, Ting-Ting Zhao, Cui-Lian Feng, Ling Li, Rui-Jie Wu, Qi-Xing Huang, Hong-Bo Liu, Jun-Gang Wang

“…Conversely, ScMAPKK13, ScRAF10, and ScZIK18 were up-regulated at specific time points under drought, with ScZIK18 exhibiting strong defense. Under NaCl stress, most genes were down-regulated, except for slight increases in ScZIK18 and ScMAPKK13, suggesting a positive role in salt stress response. …”
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Integrated transcriptomic and metabolomic analyses identify key factors in the vitellogenesis of juvenile Sichuan bream (Sinibrama taeniatus) by Zhe Zhao, Zhe Zhao, Qiang Zhao, Qiang Zhao, Haoyu Wang, Haoyu Wang, Lan Wei, Siya Wang, Siya Wang, Shilin Li, Shilin Li, Dengyue Yuan, Dengyue Yuan, Zhijian Wang, Zhijian Wang

“…Vitellogenesis is the most important stage of ovarian maturation in fish, involving the synthesis and transport of essential yolk substances and their complex mechanisms and coordination process. …”
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New insights into Wiskott-Aldrich syndrome: ten novel WAS mutations and their clinical impact in a Brazilian cohort by Lucas W. Santos, Samuel S. Medina, Jéssica O. Frade-Guanaes, Lúcia H. Siqueira, Luiz Gustavo R. de Lima, Luiz Gustavo R. de Lima, Bruna Chati, Bruna Chati, Marcos T. Nolasco da Silva, Marcos T. Nolasco da Silva, Adriana G. L. Riccetto, Adriana G. L. Riccetto, Paula Lyra, Ana Carla A. M. Falcão, Pedro P. A. Santos, Regina S. W. Di Gesu, Bianca Stefanello, Bianca Stefanello, Gabriela G. Yamaguti-Hayakawa, Carmem M. S. Bonfim, Maria M. S. Vilela, Maria M. S. Vilela, Margareth C. Ozelo, Margareth C. Ozelo

“…DNA samples underwent direct sequencing to identify WAS gene mutations.ResultsGenomic sequencing identified 17 WAS gene variants, 10 of which were novel, expanding the genetic diversity of the disorder. The most frequent WAS gene variants were primarily frameshift indels that introduced premature stop codons, with five localized in exon 10. …”
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Low-frequency rTMS modulates small-world network properties in an AVH-related brain network in schizophrenia by Lin Zhang, Li Guo, Xiaohui Liu, Jing Han, Yuanqiang Zhu, Chaozong Ma, Ye Li, Weiliang Ye

“…However, the network-level effects of rTMS remain incompletely understood, particularly in terms of small-world network properties, which provide insights into local and global network efficiency. Furthermore, most previous studies have analyzed whole-brain networks, lacking specificity regarding disease-relevant circuits.ObjectiveThis study aimed to investigate how low-frequency rTMS modulates the small-world network properties of a refined AVH-related network composed of 35 brain regions specifically implicated in hallucination generation and rTMS treatment effects, thereby providing a more targeted perspective on network reorganization. …”
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Study of novel 1,4-dihydropyridine derivatives as prospective anti-inflammatory remedies: a randomised controlled trial by E. Yu. Bibik, D. S. Krivokolysko, G. A. Batishcheva, A. A. Samokish, Yu. S. Venidiktova, A. V. Myazina, A. A. Pankov, K. A. Frolov, V. V. Dotsenko, S. G. Krivokolysko

“…Data homogeneity and reliability were estimated by variation coefficient V and the Wilcoxon T(W) criterion.Results. As the most anti-inflammatory effective, partially hydrogenated mar-040 pyridines (ethyl 4-({[5-cyano-6-{[2-(diphenylamino)-2-oxoethyl]thio}-4-(2-furyl)-2-methyl-1,4-dihydropyridin-3-yl]carbonyl}amino) benzoate) were shown 33-fold superior to indomethacin, 26-fold — to sodium diclofenac, 25-fold — to meloxicam and 30-fold — to sodium metamizole; mar-037 pyridines (ethyl 4-[({[3-cyano-5-({[4-(ethoxycarbonyl)phenyl]amino}carbonyl)-4-(2-furyl)-6-methyl-1,4-dihydropyridin-2-yl]thio}acetyl)amino] benzoate) — 17–23-fold superior vs. reference drugs. …”
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The epidemiology of Lassa fever in Ghana: a study on the 2023 Lassa fever outbreak in Ghana by Kwasi Atweri Akowuah, Magdalene Sarah Ofori, Deborah Pratt, Abigail Abankwa, Evelyn Yayra Bonney, Nancy Enimil, Eric Odei, Theodore Worlanyo Asigbee, Dennis Laryea, Prince Ketorwoley, Juliana Naa Dedei Acquah Amaning, Maame Serwaa Boapea, Stella Bour, Sally-Ann Ohene, Patrick Avevor, John Kofi Odoom, Franklin Asiedu-Bekoe, Patrick Kuma-Aboagye, Francis Chisaka Kasolo, Benjamin Abuaku, Dorothy Yeboah-Manu, Joseph Humphrey Kofi Bonney

“…Inferential statistics was used to determine associations between the study variables.ResultsThe overall positivity rate was 5.19% out of the 539 samples received. Most cases were confirmed in the Month of February. …”
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Exploring fecal microbiota signatures associated with immune response and antibiotic impact in NSCLC: insights from metagenomic and machine learning approaches by Wenjie Han, Wenjie Han, Yuhang Zhou, Yuhang Zhou, Yiwen Wang, Yiwen Wang, Xiaolin Liu, Tao Sun, Tao Sun, Junnan Xu, Junnan Xu, Junnan Xu

“…Among eight machine learning algorithms evaluated, the optimal model was selected to construct a predictive framework for immunotherapy response.ResultsMicrobial α-diversity was significantly elevated in responders compared to non-responders, with antibiotic administration further amplifying this difference—most notably at the species level. Integrative multi-omics analysis identified two pivotal microbial biomarkers, s_Bacteroides caccae and s_Prevotella copri, which were strongly associated with immunotherapy efficacy. …”
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A Snapshot of Antimicrobial Resistance in Semi-Wild Oryx: Baseline Data from Qatar by Asma Mushahidur Rahman, Salma E. Ahmed, Shayma A. Osman, Radhia A. Al-Haddad, Abdallah Almiski, Ristha Kamar, Hana Abdelrahman, Issmat I. Kassem, Andrea Dogliero, Nahla O. Eltai

“…<i>tetA</i> and <i>tetB</i> encode tetracycline resistance were the most frequently detected genes (57.7%). Whole genome sequencing (WGS) was used to expand on AMR gene-PCR analyses and analyze the resistome of 12<i>E. coli</i> isolates. …”
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The experience industries as a space for the application of "soft power" / Индустрия впечатлений как пространство аппликации «мягкой силы»... by Vasiliy Smirnov / Смирнов Василий Андреевич

“…The article considers the possibility of using “soft power” tools in the space of modern “cultural industries”. Most researchers focus their attention on the criticism of mass culture, considering it too commercialized, and therefore broadcasting exclusively primitive content. …”
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Enhanced machine learning models for predicting three-year mortality in Non-STEMI patients aged 75 and above by Jing Zhang, Wuyu Xiong, Chengzhi Zhang, Cuiyuan Huang, Wenqiang Li, Li Liu, Wei Wang, Ye Sang, Huiling Zhen, Caiwei Tan, Jiajuan Yang, Jian Yang

“…SHapley Additive exPlanations (SHAP) analysis was used to determine the top contributing features influencing mortality, with PCI, age, and P(bpm) identified as the most critical factors. A web-based calculator was also developed to support clinical decision-making. …”
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Team climate, job satisfaction, burnout and practice performance: results of a national survey of staff in general practices in England by Peter Williams, Heather Gage, Bridget Jones, Carole Aspden, Jessica Smylie, Thomas Bird, Morro M. L. Touray, Phelim Brady, John Campbell, Rupa Chilvers, Catherine Marchand, Stephen Peckham, Suzanne H. Richards, Karen Spilsbury, Mark Joy, Simon de Lusignan

“…Results A total of 9835 individual members of staff from 809 practices participated. Most indicated a favourable team climate in their practice, (mean 3.77, on scale 1–5 best, SD 0.84); 61.3% stated they were mostly or extremely satisfied in their jobs; 26.1% met the criteria for high burnout. …”
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Mother’s Day Superstorms: Pre- and Post-storm Evolutionary Patterns of ARs 13664/8 by Mausumi Dikpati, Marianna B. Korsós, Aimee A. Norton, Breno Raphaldini, Kiran Jain, Scott W. McIntosh, Peter A. Gilman, Andre S. W. Teruya, Nour E. Raouafi

“…By analyzing both global warped toroids on which the active regions are strung, and active-region-scale magnetic flux and helicity, we find (i) the north and south toroids have nearly identical warped patterns, with mostly longitudinal wave numbers m  = 1–3; (ii) in three longitude intervals the north and south toroids were tipped away from each other in latitude, with a longitude phase shift between them, creating locations most prone to AR eruptions; (iii) on an active region scale, vector magnetic fields deviate far from potential fields, and therefore contain large amounts of magnetic “free energy” available for conversion into kinetic energy and high-temperature radiation; (iv) the positive and negative polarities converge toward each other, facilitating reconnection and magnetic energy release; and (v) rapid changes in magnetic helicity, caused by helicity injection from below that creates helicity imbalances. …”
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Objective measurement methods for the evaluation of socket comfort in patients with transfemoral amputation: a systematic review by Lisa Marie Tiesler, Lisa Marie Tiesler, Melanie Edel, Melanie Edel, Fangxing Wang, Fangxing Wang, Philipp Pieroh, Welf-Guntram Drossel, Welf-Guntram Drossel, Alina Carabello, Alina Carabello, Daniel Zipplies, Christoph-Eckhard Heyde, Stefan Schleifenbaum, Stefan Schleifenbaum, Stefan Schleifenbaum

“…Consequently, this review aims to explore methods for identifying issues at the socket-limb interface through both objective and subjective measurement approaches.MethodsAll articles available in MEDLINE and Web of Science up to May 2024 were screened and evaluated, with the authors conducting a quality assessment.ResultsThe socket design was the most frequently studied factor influencing the socket-limb interface (11/25), with investigations addressing challenges such as volume fluctuations (5/25), pressure and shear forces (4/25), femur pistoning (3/25), perspiration and ventilation (2/25), and prosthesis alignment (1/25). …”
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