Identification of robust and abundant reference transcripts for EV mRNA cargo normalization by Antje M. Zickler, Radosław Grochowski, André Görgens, Erik Bäcklin, Maximilian Kordes, J.-Matthias Löhr, Joel Z. Nordin, Samir EL Andaloussi, Daniel W. Hagey

“…We identify 11 transcripts that are shared amongst the 50 most abundant in EVs from all of these cell sources. …”
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Prevalence and Spatial distribution characteristics of human echinococcosis in Ningxia Hui Autonomous Region, 2011–2023 by Hongju Duan, Xianglin Wu, Fan Wang, Qianqian Cui, Xueping Ma, Liying Wang

“…Additionally, spatial scanning analysis identified four spatial clusters, including one most likely cluster(LLR = 335.53, RR = 4.13, P<0.01)and three secondary likely clusters. …”
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Identification of a 2-phenoxychromone derivative as a novel inhibitor of lipid droplet formation in hepatocytes and adipocytes by Yu-Tsen Hsieh, Tung-Hsuan Kang, Hsin-Yi Hung, Yi-Han Chang, Kuan-Chen Cheng, Chia-Yih Wang, Wen-Tai Chiu, Pai-Sheng Chen, Shih-Chieh Lin, I-Chen Peng

“…Dysregulated lipid droplet (LD) accumulation in hepatocytes increases the risk of metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as non-alcoholic fatty liver disease (NAFLD), the most common chronic liver disease worldwide. Furthermore, excessive accumulation of LD in adipocytes leads to obesity, insulin resistance, and metabolic complications, including MASLD. …”
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Global high-resolution fire-sourced PM_2.5 concentrations for 2000–2023 by Y. Hu, C. Tian, X. Yue, Y. Lei, Y. Cao, R. Xu, Y. Guo

“…Both datasets show consistent spatial distributions with regional hotspots in central Africa and widespread decreasing trends over most areas. While the mean levels of fire-sourced [PM<span class="inline-formula">_2.5</span>] are much higher at low latitudes, fire episodes in the boreal regions can cause PM<span class="inline-formula">_2.5</span> levels that are comparable to those of the tropics. …”
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Impact analysis of constructed wetland for wastewater management in Rwanda by Justin Nsanzabaganwa, Justin Nsanzabaganwa, Justin Nsanzabaganwa, Justin Nsanzabaganwa, Xi Chen, Xi Chen, Xi Chen, Xi Chen, Tie Liu, Tie Liu, Tie Liu, Tie Liu, Christophe Mupenzi, Egide Hakorimana, Egide Hakorimana, Egide Hakorimana, Egide Hakorimana, Richard Mind'je, Marie Louise Mujawayezu, Aboubakar Gasirabo, Aboubakar Gasirabo, Aboubakar Gasirabo, Aboubakar Gasirabo, Adeline Umugwaneza, Adeline Umugwaneza, Adeline Umugwaneza, Flora Malayika, Schadrack Niyonsenga

“…The results revealed that, the most parameters have been exceeding the standards before being treated, then after all effluents responded to standard conditions. …”
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Heterogeneity of metastatic gastric cancer: solitary non-regional lymph node metastasis and solitary lung metastasis showed better survival outcomes than other metastatic patterns by Xiaoyi Luan, Xue Han, Zerong Wang, Lulu Zhao, Xiaojie Zhang, Wanqing Wang, Penghui Niu, Danjun Wang, Dongbing Zhao, Mingwei Zhu, Yingtai Chen

“…Liver (772 [37.9%]), peritoneum (765 [37.6%]), and non-regional lymph node (692 [34.0%]) were the most three common metastasis organs for metastatic gastric cancer patients in our study. …”
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Age and origin of the gabbros in the Jilotlán pluton, Jalisco: primitive magmatic rocks in the southern part of the Guerrero terrane by Daniel Villanueva-Lascurain, Gabriela Solís-Pichardo, Peter Schaaf, Teodoro Hernández-Treviño, Josué Salazar-Juárez, Pedro Corona-Chávez

“…Clinopyroxene crystals and hornblende pseudomorphs have plagioclase inclusions, suggesting exsolution by a rapid uplift. Geochemically, most gabbros are calc-alkaline. The relatively flat trace element patterns display incompatible element (LILE and LREE) en- richment relative to the less incompatible elements (HFSE and HREE), which show minor enrichment or are even depleted with respect to N-MORB. …”
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Anomaly Detection Algorithms for Real-Time Log Data Analysis at Scale by Andras Horvath, Andras Olah, Attila Pinter, Balint Siklosi, Gergely Lukacs, Istvan Z. Reguly, Kalman Tornai, Tamas Zsedrovits, Zoltan Mathe

“…Our results underscore the importance of selecting the right balance between sophistication and simplicity, challenging the assumption that the most sophisticated methods are necessary for effective anomaly detection in real-world log data.…”
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Impaired neural encoding of naturalistic audiovisual speech in autism by Theo Vanneau, Michael J. Crosse, John J. Foxe, Sophie Molholm

“…Understanding the neural basis of impaired MSI in ASD, especially during naturalistic speech, is critical for developing targeted interventions. Most neurophysiological studies have relied on simplified speech stimuli (e.g., isolated syllables or words), limiting their ecological validity. …”
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Ensuring the unity of the federal system of scientific and methodological support for teacher professional development: Opportunities and risks by A. V. Zolotareva, L. V. Bayborodova, M. V. Gruzdev, I. G. Kharisova

“…Currently, the creation of conditions for the continuing professional development of teaching staff is one of the most relevant and discussed problems in international studies. …”
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Screening of the Alcohol Fraction of <i>Ferula akitschkensis</i> B. Fedtsch. ex Koso-Pol. by GC/MS Method by A. M. Jumabayeva, A. S. Kozhamzharova, L. N. Ibragimova, I. I. Terninko, E. S. Surbeeva, Z. B. Sakipova

“…The development of dermatological drugs may also be in the focus of scientific groups due to the anti-eczematous activity of most compounds of the ethanolic extract of the roots of Ferula akitschkensis.…”
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Lacticaseibacillus rhamnosus P118 enhances host tolerance to Salmonella infection by promoting microbe-derived indole metabolites by Baikui Wang, Xianqi Peng, Xiao Zhou, Xiuyan Jin, Abubakar Siddique, Jiayun Yao, Haiqi Zhang, Weifen Li, Yan Li, Min Yue

“…Salmonella is one of the most common foodborne pathogens, resulting in inflammatory gastroenteritis and frequently accompanied by dysbiosis. …”
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Noise Levels Due to Commercial and Leisure Activities in Urban Areas: Experimental Validation of a Numerical Model Fed with Crowd Density Estimation Using Computer Vision by Óscar Ramón-Turner, Jacob D. R. Bordón, Asunción González-Rodríguez, Javier Lorenzo-Navarro, Modesto Castrillón-Santana, Guillermo M. Álamo, Román Quevedo-Reina, Carlos Romero-Sánchez, Antonio T. Ester-Sánchez, Cristina Medina, Fidel García, Orlando Maeso, Juan J. Aznárez

“…In the real problem, in general terms and taking into account that the study is carried out on pedestrian streets, it seems that the model is able to reproduce most of the noise of anthropogenic origin.…”
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Comparative life cycle greenhouse gas emission and cost assessment of hydrogen fuel and power for Singapore by Yinjin Lee, Eugene Kok, Soo Lin Goh, Keying Chen, Eugene Hong Zhuang Ho, Yong Jie Leow, Daren Zong Loong Tan, Zhiquan Yeo, Hsien Hui Khoo, Experience I. Nduagu, Wenzhao (Tony) Wu, Saifudin M. Abubakar, Jonathan Sze Choong Low

“…When also considering emerging technologies, turquoise H2 produced with the thermal decomposition of methane locally or in Malaysia is the most economical solution, while wind-generated H2 from Australia transported as liquefied H2 or NH3 produce the least GHG emissions. …”
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COVID-19 knowledge, attitudes and practices in Thabo Mofutsanyana District, South Africa, 2022 by Inge Kleinhans, Siphesihle K. Mahanjana, Lehlohonolo Kumalo, Brian Brümmer, Ashley Chitaka, Zandile D. Nukeri, Fiona Els, Sizeka Mashele, Michelle Groome, Natalie Mayet, Ramasedi S. Mokoena, Emily B. Atuheire, Joy I. Ebonwu

“…Results: A total of 551 participants’ data were analysed, most of whom were 40 years (63%) and female (68%). …”
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Genomic changes during the evolution of the Coxiella genus along the parasitism-mutualism continuum by Santos-Garcia, Diego, Morel, Olivier, Henri, Hélène, El Filali, Adil, Buysse, Marie, Noël, Valérie, McCoy, Karen D., Gottlieb, Yuval, Klasson, Lisa, Zenner, Lionel, Duron, Olivier, Vavre, Fabrice

“…Indeed, the virulence factor Dot/Icm T4 Secretion System is present in most, but not all, Coxiellaceae. Whereas it is part of a putative pathogenic island in C. burnetii, it has been entirely lost or inactivated in Coxiella-LEs, suggesting its importance in pathogenesis. …”
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Real-world performance of the CALGB 10403 regimen in young adults in the United States by Brandon DaSilva, Alicia Darwin, Amy Zhang, Rutu D. Vyas, Kathryn Russell, Jason S. Gilbert, Virginia Tan, Susan Feldt, Hannah Johnston, Emily C. Liang, Adam S. DuVall, Michaela Liedtke, Wendy Stock, Ryan D. Cassaday, Marc Schwartz, Jessica T. Leonard, Lori S. Muffly, Marlise R. Luskin

“…Four deaths occurred while on C10403 treatment: 1 during induction; and 3 later in the treatment course. The most common grade 3 or 4 adverse events during induction included alanine aminotransferase elevation (22%) and sepsis (14%). …”
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Comparison of perioperative efficacy and indications between laparoscopic capsule-preserving resection and partial nephrectomy for renal angiomyolipoma: a decade-long retrospective... by Haipeng Zhang, Guangcan Yang, Changxiu Tian, Wei Song, Houliang Zhang, Jinliang Ni, Ziming Jiang, Keyi Wang, Bo Peng

“…Multivariate regression analysis was employed to identify patient characteristics that are most suited for LCPR. Methods We retrospectively analyzed the clinical data of 209 patients diagnosed with RAML and treated surgically at our hospital between January 2010 and December 2023. …”
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Analisis Dukungan Petugas Kesehatan Dalam Optimalisasi Competence Baby Care Pada Ibu muda Melalui Pendekatan Maternal Sensitivity Models Berbasis Keluarga (Analysis of Health Of... by diyan indriyani

“…The data were then analyzed both in quantitative and qualitative methods.Results: The findings confirmed that the most common diseases undergone by infants were respiratory infections, such as diarrhea and febrile. …”
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Anticancer Potential, Phenolic Profile, and Antioxidant Properties of <i>Synsepalum dulcificum</i> (Miracle Berry) in Colorectal Tumor Cell Lines by Josefa Quiroz-Troncoso, Nicolás Alegría-Aravena, Blanca Sáenz de Mierae, Marta Sánchez-Díez, Raquel González-Martos, Clara E. Gavira-O’Neill, Emilio J. González, Maria González-Miquel, Cristian Valdés Vergara, Gloria González-Silva, Loan Bensadon-Naeder, Javier Galeano, Carmen Ramírez-Castillejo

“…An aqueous extract of DMB^® was obtained, and 12 compounds were identified through high-performance liquid chromatography (HPLC), with protocatechuic acid, gallic acid, and catechin being the most prominent. Regarding cytotoxicity, the extracts reduced cell viability in the DLD-1, HT29, SW480, and SW620 cell lines, with IC₅₀ values of 7, 11, 13, and 15 mg/mL, respectively. …”
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