Effects of polyethylene glycol stress on ion contents in nutritive organs of alfalfa seedlings by LI Bo, XU Wanyu, SHI Shanliang

“…Alfalfa, a kind of perennial leguminous plant, is the best and most important leguminous grass in the world. It plays important roles in the development of animal husbandry and the improvement of agricultural ecological environment. …”
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Transcriptomics assisted by metabolomics analysis provides insights into regulation mechanisms during carcinogenic process in a hydrodynamically transfected liver cancer model by Qi Zhang, Yongfeng Li, Xiaojing Cheng, Zhouxiang Liao, Sha Wen, Xuejing Huang, Zhenyu Song, Min He, Lichao Yang

“…Abstract Background Hepatocellular carcinoma (HCC) ranks among the most prevalent malignancies with a substantial mortality rate, and its pathogenesis is relatively complex. …”
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Network pharmacology-driven investigation of luteolin from Annona muricata as a promising multi-target inhibitor for pancreatic cancer by Shalini Mathpal, P. Priyamvada, Gayathri Ashok, Tushar Joshi, Deepanjan Saha, Ankit Mukherjee, Biraj Roy, Sudha Ramaiah, Anand Anbarasu

“…Molecular docking studies identified luteolin and kaempferol as the most effective compounds, exhibiting strong binding affinities across the hub targets, with luteolin demonstrating the lowest binding energies. …”
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Midfoot Charcot and Need for Arch Reconstruction and Superconstruct—“Lessons Learnt”: Multicentric Indian Experience by Rajagopalakrishnan Ramakanth, Rajesh Simon, Silvampatti Ramasamy Sundararajan, Abhishek Kini, Pratheeban Karthikeyan, Terence Dsouza, Shanmuganathan Rajasekaran, Madhu Periasamy

“…The total complication rate ranged between 46% and 51% [minor (6–23%), major (25–40%)] with screw breakage at the TMT junction being the most common complication encountered. The reoperation rate ranged from 0 to 27% across the centers. …”
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Impact of methyl Jasmonate on blueberry ripening fruits: assessment of cell wall thermal stability, nutritional parameters and antioxidant enzymatic activity by Carlos Vasquez-Rojas, Carlos Vasquez-Rojas, Marcelo Muñoz-Vera, Sebastián Flores, Mauricio Betancourt, Mauricio Betancourt, Ricardo I. Castro, Patricio Ramos, Patricio Ramos, Daniel Laporte, Carolina Parra-Palma, Luis Morales-Quintana

“….), recognized as one of the most significant horticultural crops globally, is valued for its rich bioactive compounds. …”
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Cochlear Implant in Children with Congenital CMV Infection: Long-Term Results from an Italian Multicentric Study by Francesca Forli, Silvia Capobianco, Stefano Berrettini, Francesco Lazzerini, Rita Malesci, Anna Rita Fetoni, Serena Salomè, Davide Brotto, Patrizia Trevisi, Leonardo Franz, Elisabetta Genovese, Andrea Ciorba, Silvia Palma

“…<b>Background/Objectives</b>: Congenital cytomegalovirus (cCMV) infection is the most common non-genetic cause of sensorineural hearing loss (SNHL) in children. …”
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Genetic heterogeneity in familial forms of genetic generalized epilepsy: from mono- to oligogenism by Maha Dahawi, Jean-Madeleine de Sainte Agathe, Mohamed S. Elmagzoub, Elhami A. Ahmed, Julien Buratti, Thomas Courtin, Eric Noé, Julie Bogoin, Bruno Copin, Fatima A. Elmugadam, Wasma A. Abdelgadir, Ahmed K. M. A. Ahmed, Mohamed A. Daldoum, Rayan Mamoon Ibrahim Altayeb, Mohamed Bashir, Leena Mohamed Khalid, Sahar Gamil, Sara Baldassari, Liena Elsayed, Boris Keren, Gregory Nuel, Ammar E. Ahmed, Eric Leguern

“…Moreover, a polygenic mode of inheritance is suspected in most cases. We performed SNP microarrays and whole exome sequencing in 20 families from Sudan, focusing on those with at least four affected members. …”
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Expression of HERV-K and embryonic genes in chronic lymphocytic leukemia and their association with therapy regimens by Claudia Matteucci, Vita Petrone, Alessandro Giovinazzo, Roberta Laureana, Massimiliano Postorino, Livio Pupo, Chiara Cipriani, Nicola Toschi, Marialaura Fanelli, Antonella Minutolo, Giovangiacinto Paterno, Elisa Buzzatti, Paola Sinibaldi Vallebona, Antonella Zucchetto, Federico Pozzo, Valter Gattei, Giovanni Del Poeta, Adriano Venditti, Emanuela Balestrieri, Maria Ilaria Del Principe

“…In the field of onco-hematology, some studies have described alterations of HERV expression in chronic lymphocytic leukemia (CLL), the most common adult leukemia in the Western world. …”
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Age-Onset-Related Particularities of Pediatric MS—Understanding the Spectrum: A Tertiary Center Experience by Alice Denisa Dică, Dana Craiu, Florentina Ionela Linca, Magdalena Budișteanu, Catrinel Iliescu, Carmen Sandu, Cristina Pomeran, Diana Bârcă, Niculina Butoianu, Carmen Burloiu, Ioana Minciu, Ina Ofelia Focșa, Dana Surlică, Oana Tarța-Arsene, Cristina Cazacu, Andreea Badea, Alexandru Stefan Niculae, Daniela Adriana Ion

“…EDSS scores tended to remain stable in the first 2–3 years, but early-onset patients showed a notable decline after the fourth year. While most patients received disease-modifying therapies, high-efficacy agents were underused due to age-related restrictions. …”
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Eletroforese das proteínas do líqüido cefalorraquidiano na cisticercose do sistema nervoso central by A. Spina-França

“…Concerning CNS cysticercosis, if CSF total protein content and electrophoretic data on its fractions are considered together (table IS and 19; graph. 1), it is possible to evidence that at least two mechanisms participate in the origin of protein changes (tables 20 and 21; graph. 2) : blood-CSF barrier disturbances are able to explain data concerning albumin, a and globulin changes, which are similar; the local production of y-globulin is the hypothesis most reliable to explain the peculiar changes of this fraction. …”
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Lipidomic signatures of ventilator-associated pneumonia in COVID-19 ARDS patients: a new frontier for diagnostic biomarkers by Arthur Kassa-Sombo, Charles Verney, Augustin Pasquet, Julien Vaidie, Deborah Brea, Virginie Vasseur, Adeline Cezard, Antoine Lefevre, Camille David, Eric Piver, Lydie Nadal-Desbarats, Patrick Emond, Hélène Blasco, Mustapha Si-Tahar, Antoine Guillon

“…Phosphatidylcholines were the most represented with 17 significantly upregulated and 6 downregulated lipids. …”
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Heel kicking exercise rapidly improves pain and function in patients with acute lateral ankle sprain: a randomized controlled trial by Qi-Ning Qin, Xin Zhang, Ying-Feng Cai, Tian-Zhao Tian, Jian-Peng Zhou, Lin Li, Min Shi, Peng Huang, Hao-dong Liang, Jia-Hui Li, Zhan-Liang Tan, Yi-Xuan Fang, Jia-Wen Wang, Fang Zheng, Bao-Xin Liu

“…In addition, patients in the intervention group were observed to get a quicker pain reliever, swelling subsiding, and ankle function restore than those in control group at most of time points of observation (1st d, 3rd d, 1st w, 2nd w, 4th w) (p < 0.05, p < 0.01). …”
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Discovery of a novel class NSD2 inhibitor for multiple myeloma with t(4;14)+ by Sae Matsuoka, Naoki Osada, Hirokazu Kubota, Ko Kikuzato, Hiroo Koyama, Takeshi Sonoda, Akiko Idei, Minoru Yoshida, Masaki Kikuchi, Takashi Umehara, Chiduru Watanabe, Teruki Honma, Hiroshi Yasui, Sho Ikeda, Naoto Takahashi, Hideki Nakasone, Jiro Kikuchi, Yusuke Furukawa

“…Of such abnormalities, t(4;14) is the second most common, occurring in 15% of patients with MM. …”
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Small Intestinal Bacterial Overgrowth in Various Specialties of Medical Practice (Literature Review and Expert Council Resolution) by V. T. Ivashkin, V. V. Fomin, O. N. Tkacheva, O. S. Medvedev, E. A. Poluektova, D. I. Abdulganieva, S. R. Abdulkhakov, O. P. Alexeeva, S. A. Alekseenko, D. N. Andreev, A. Yu. Baranovsky, M. S. Zharkova, O. Yu. Zolnikova, K. V. Ivashkin, I. L. Kliaritskaia, N. V. Korochanskaya, S. N. Mammaev, R. V. Maslennikov, R. G. Myazin, M. V. Perekalina, A. V. Povtoreyko, A. I. Ulyanin, M. V. Fadeeva, I. B. Khlynov, V. V. Tsukanov, O. S. Shifrin

“…Saccharomyces boulardii CNCM I-745 is thought to be the most studied, promising probiotic. The review also presents statistical data on the issues in the diagnosis and treatment of SIBO in the regions of the Russian Federation.Conclusion. …”
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Fibroblasts activated by miRs-185-5p, miR-652-5p, and miR-1246 shape the tumor microenvironment in triple-negative breast cancer via PATZ1 downregulation by Giada De Luca, Gianluca Petrillo, Iolanda Scognamiglio, Katia Pane, Lorenza Cocca, Giuseppina Roscigno, Martina Mascolo, Claudia Pignataro, Sara Verde, Aurelia Fraticelli, Danilo Fiore, Alessandra Affinito, Silvia Nuzzo, Zoran Minic, Francesca De Micco, Guglielmo Thomas, Monica Franzese, Maxim V. Berezovski, Monica Fedele, Gerolama Condorelli, Cristina Quintavalle

“…Bioinformatic analysis identified the transcriptional factor PATZ1 as a potential regulator of the 12 most highly upregulated proteins. Consistently, in-silico predictions and in vitro experiments confirmed that PATZ1 is a direct target of miR-185-5p and miR-652-5p. …”
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Using nominal group technique to identify and prioritize barriers to decentralizing HIV care to primary health centers in Lima, Peru by David Oliveros, Kelika A. Konda, Lynn M. Madden, Juan José Montenegro-Idrogo, Karla T. Tafur Quintanilla, Karin Sosa Barbarán, Benjamin M. Nikitin, Matthew Ponticiello, Carlos M. Benites, Jorge Sánchez, Frederick L. Altice

“…Abstract Background Decentralizing HIV services is an evidence-based strategy recommended by the World Health Organization to expand healthcare access by shifting most HIV care from specialty (SHCs) to primary health centers (PHCs) with the goal of maximizing health outcomes. …”
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Implementation and maintenance of breast cancer screening among Chinese rural women: a mixed-methods evaluation based on RE-AIM framework by Huijiao Yan, Qiankun Wang, Le Dang, Xianzhi Duan, Zhirong Bai, Yinhui Feng, Linlin Zhang, Suyala Qimuge, Haiying Gao, Xinchun Wang, Min Sun, Shuxia Ma, Cailing Yan, Fanghui Zhao, Youlin Qiao

“…The “rural outreach” model (where MCHHs conduct screenings by visiting rural villages and setting up temporary clinics at local village health centers), along with routine hospital screening, was seen as the most effective solution for reaching dispersed populations with low health awareness and literacy. …”
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Contraception use and pregnancy in women receiving a 2-dose Ebola vaccine in Rwanda: A retrospective analysis of UMURINZI vaccination campaign data. by Rosine Ingabire, Julien Nyombayire, Amelia Mazzei, Jean-Baptiste Mazarati, Jozef Noben, Michael Katwere, Rachel Parker, Sabin Nsanzimana, Kristin M Wall, Tyronza Sharkey, Felix Sayinzoga, Amanda Tichacek, Niina Hammoud, Ellen Martinson, Ben Magod, Susan Allen, Etienne Karita

“…<h4>Conclusions</h4>Many fertile and sexually active women who sought vaccination during UMURINZI were not using contraception prior to vaccination, and contraceptive method uptake after family planning counseling and method provision was low. Most women who became pregnant after the first vaccination dose did not receive the second dose, thus potentially reducing protection against Ebola. …”
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Spatiotemporal estimation of ambient forest phytoncides: Unveiling patterns through geospatial-based machine learning approach by Aji Kusumaning Asri, Hao-Ting Chang, Chia-Pin Yu, Wan-Yu Liu, Yinq-Rong Chern, Rui-Hao Xie, Shih-Chun Candice Lung, Kai Hsien Chi, Yu-Cheng Chen, Sen-Sung Cheng, Gary Adamkiewicz, John D. Spengler, Chih-Da Wu

“…The results showed that RF and XGB were the most effective algorithms, explaining approximately 83.3% and 98.4% of the spatiotemporal variability in camphene and α-pinene, respectively. …”
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Adolescent vaccine introductions scoping review: A decade of insights from low- and middle-income countries (2013−2023) by Arman Majidulla, Amelia K. Gerste, Anurima Baidya, Onimitein Georgewill, Kirthini K. Muralidharan, Degu J. Dare, Joeri S. Buis, Michelle M. Gill, Julie A. Denison, Andrew D. Kerkhoff, Rupali J. Limaye

“…During implementation, school-based delivery was the most common approach, often supplemented by community outreach and mop-up activities to reach out-of-school adolescents. …”
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