Dynamics of concomitant therapy in children with juvenile idiopathic arthritis treated with etanercept and methotrexate by Ekaterina Alexeeva, Tatyana Dvoryakovskaya, Rina Denisova, Tatyana Sleptsova, Kseniya Isaeva, Alexandra Chomahidze, Anna Fetisova, Anna Mamutova, Alina Alshevskaya, Victor Gladkikh, Andrey Moskalev

“…Conclusion: Therapy with ETA makes it possible to reduce the dosage or completely discontinue most concomitant medications (orGCs, NSAIDs, MTX) in a significant percentage of patients. …”
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Day-case hip and knee arthroplasty does not increase healthcare system contacts: a prospective multicenter study in a public healthcare setting by Abdullahi Abdirisak Hirsi, Oddrún Danielsen, Claus Varnum, Thomas Jakobsen, Mikkel Rathsach Andersen, Manuel Josef Bieder, Søren Overgaard, Christoffer Calov Jørgensen, Henrik Kehlet, Kirill Gromov, Martin Lindberg-Larsen

“…Specific contacts included visits to a general practitioner (GP) or out-of-hours medical clinic (25% [CI 22–27] vs 32% [CI 29–35]), the emergency department (ED) (6% [CI 4–7] vs 7% [CI 5–8]), and outpatient clinics or wards (35% [CI 33–38] vs 35% [CI 32–38]). The most common reasons for all types of healthcare contacts were wound problems, prescription renewals, and pain management. …”
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Association of the newly proposed dietary index for gut microbiota and all-cause and cardiovascular mortality among individuals with diabetes and prediabetes by Wenjing Song, Daoqin Liu, Zihe Xing, Luqing Jiang, Yu Tang, Zichen Xu, Lei Li, Shuai Yan, Xia Fu, Yuping Wang, Qiwen Wu

“…Subgroup analyses confirmed the consistency of the results in most categories. Restricted cubic splines demonstrated negative correlations between DI-GM and both mortality outcomes. …”
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Evidence of SARS‐CoV‐2 Exposure in Cats and Dogs From Households in Romania and Long‐Term Specific Seroconversion in Cats by Luanda Elena Oslobanu, Luciana Alexandra Crivei, Gheorghe Savuta, Laro Gómez‐Marcos, Pablo Nogales‐Altozano, José M. Rojas, Noemí Sevilla

“…One cat maintained antibodies for over a year, though with reduced titers. Most cats' antibodies did not cross‐react with the Omicron strain, indicating limited cross‐reactivity. …”
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Second Victim Syndrome Among Healthcare Professionals: A Systematic Review of Interventions and Outcomes by Ong TSK, Goh CN, Tan EKYE, Sivanathan KA, Tang ASP, Tan HK, Ng QX

“…Peer support programs were the most commonly implemented interventions, often structured around the Scott Three-Tiered Model. …”
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EvoNB: A protein language model-based workflow for nanobody mutation prediction and optimization by Danyang Xiong, Yongfan Ming, Yuting Li, Shuhan Li, Kexin Chen, Jinfeng Liu, Lili Duan, Honglin Li, Min Li, Xiao He

“…Through mutation prediction and systematic analysis of key sites, we can quickly predict the most promising variants for experimental validation without relying on traditional evolutionary or selection processes. …”
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Flexural behavior of RC beams strengthened with CFRP sheets and ECC layers by Xiaobing Hou, Ziyi Song, Han Song, Xingyao Wang, Junhua Guo, Songqiang Wan, Jingli Yang, Hongbo Xiao, Yanfen Gong, Long Liu

“…The findings indicate that the rebar ratio has the most significant influence on the flexural capacity of CESB. …”
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A Systematic Review on the Occurrence of <i>Babesia</i> spp. and <i>Anaplasma</i> spp. in Ticks and Wild Boar from Europe—A 15-Year Retrospective Study by Ioan Cristian Dreghiciu, Diana Hoffman, Tiana Florea, Ion Oprescu, Simona Dumitru, Mirela Imre, Vlad Iorgoni, Anamaria Plesko, Sorin Morariu, Marius Stelian Ilie

“…Molecular detection methods, primarily PCR and sequencing, were the most used diagnostic tools. Results indicate substantial regional variations in the prevalence of <i>Babesia</i> and <i>Anaplasma</i> spp. …”
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Influence of Noninvasive Respiratory Support Techniques on Gas Exchange in Cardiac Surgical Patients Suffering from Post-Operative Respiratory Failure by A. A. Eremenko, Р. V. Polyakova, M. A. Vyzhigina

“…Compared to NIPPV, high-flow ventilation renders most significant positive effect on elimination of CO2, RR and SpO2, and is better tolerated by patients.…”
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Exploring the determinants of AIGC usage intention based on the extended AIDUA model: a multi-group structural equation modeling analysis by Xueyan Bai, Lin Yang, Lin Yang

“…Regarding effort expectancy, hedonic motivation and technological transparency demonstrate the most prominent effects, implying that system design should emphasize user experience enjoyability and transparency. …”
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U-Pb geochronology and Hf isotopes of the Grenvillian Río Hondo gneisses, Puebla: redefining the western edge of Oaxaquia by Luigi A. Solari, Mariano Elías Herrera, Guillermo Espejo-Bautista, Mariana Jaramillo-Jaramillo, María del Consuelo Macías Romo, Carlos Ortega-Obregón

“… In situ Río Hondo (Puebla, southern Mexico) gneiss samples, as well as clastic samples recovered from the nearby-outcropping latest Paleozoic Matzitzi Formation, a fluvial unit mainly sourced by Grenvillian rocks,  were historically interpreted as representative of the northernmost exposures of the Oaxacan Complex, the largest outcrop of ortho and metasedimentary units, made up of mostly 1.0–1.3 Ga protoliths, affected cfby local migmatization (ca. 1.1 Ga) and granulite facies metamorphism at ca. 0.98 Ga, constituting the most prominent outcrop of the Oaxaquia microcontinent. …”
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Systematic elucidation of the effective constituents and potential mechanisms of Scrophulariae Radix against neoplasm based on LC-MS, network pharmacology, and molecular docking ap... by Shu-jie Yu, Xiao-bin Kong, Xin Jin, Meng-yi Shan, Gang Cheng, Pei-lu Wang, Wen-long Li, Pei-yuan Zhao, Yun-jie Sheng, Bing-qian He, Qi Shi, Hua-qiang Li, Qi-ming Zhao, Lu-ping Qin, Lu-ping Qin, Xiong-yu Meng, Xiong-yu Meng

“…Subsequently, to screen which constituents were most effective, the network pharmacology was constructed, and 96 active compounds and 488 key neoplasm-related targets were identified, leading to the establishment of the “Drug-Compound-Target” network and PPI network. …”
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Dynamic simulation and key influencing factors of carbon storage in the water-depleted zones of an arid Inland River Basin: Insights from the Tarim River mainstream by Kun Liu, Bin Wu, Fan Gao, Yunfei Chen, Bing He, Abdul Waheed, Aishajiang Aili, Zhiyuan Xu, Fanghong Han, Hailiang Xu

“…The results revealed that over the past three decades, the most significant land transitions in the Tarim River mainstream occurred in cultivated and build-up land. …”
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Physicochemical properties of bioactive bioplastics based on cellulose from coffee and cocoa by-products by Robin Oblitas, Luz Quispe-Sanchez, Grobert Guadalupe, Elgar Hernandez Diaz, Segundo Oliva, Jorge R. Diaz-Valderrama, Ives Yoplac, Cristina Valencia-Sullca, Segundo G. Chavez

“…The results demonstrated that the bioplastics with 3 % cocoa pod cellulose (CMC) and 0.05 % bioactive extract exhibited the highest whiteness index (86.9) and the most excellent flexibility (32.24 N). In contrast, formulations comprising 6 % CMC exhibited reduced water activity (0.49). …”
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Augmenting precision medicine via targeted RNA-Seq detection of expressed mutations by Dan Li, Jianying Li, Donald J. Johann, Daniel Butler, Guangchun Chen, Jonathan Foox, Binsheng Gong, Wendell Jones, David P. Kreil, Rebecca Kusko, Paweł P. Łabaj, Anne Bergstrom Lucas, Christopher E. Mason, Christopher Mozsary, Natalia Novoradovskaya, Carlos Pabón-Peña, Bohu Pan, Todd A. Richmond, Roberta Maestro, Sayed Mohammad Ebrahim Sahraeian, Andreas Scherer, Hagen U. Tilgner, James C. Willey, Pierre R. Bushel, Joshua Xu

“…Abstract In precision medicine, DNA-based assays are currently necessary but not always sufficient for predicting therapeutic efficacy of cancer drugs based on the mutational findings in a patient’s tumor specimen. Most drugs target proteins, but it is challenging and not yet cost-effective to perform high-throughput proteomics profiling, including mutational analysis, on cancer specimens. …”
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The Australian Traumatic Brain Injury Initiative: Systematic Review of Clinical Factors Associated with Outcomes in People with Moderate-Severe Traumatic Brain Injury by Ancelin McKimmie, Jemma Keeves, Adelle Gadowski, Matthew K. Bagg, Ana Antonic-Baker, Amelia J. Hicks, Regina Hill, Nyssa Clarke, Andrew Holland, Bill Veitch, Daniel Fatovich, Sandy Reeder, Lorena Romero, Jennie L. Ponsford, Natasha A. Lannin, Terence J. O’Brien, D. Jamie Cooper, Nick Rushworth, Melinda Fitzgerald, Belinda J. Gabbe, Peter A. Cameron

“…The clinical predictors most frequently associated with these outcomes were the Glasgow Coma Scale, pupil reactivity, and blood pressure measures. …”
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Laser in situ keratomyleusis (LASIK) for correction of myopia and hypermetropia: Our one year experience by Vukosavljević Miroslav, Milivojević Milorad, Resan Mirko, Cerović Vesna

“…Laser in situ keratamileusis (LASIK) is the most commonly used refractive surgical method worldwide. …”
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Immunological features in anti-U1-ribonucleoprotein antibody positive patients with systemic scleroderma by R. U. Shayakhmetova, L. P. Ananyeva, O. A. Koneva, M. N Starovoitova, O. V. Desinova, O. B. Ovsyannikova, L. A. Garzanova

“…Comparison of the three groups showed that the specific feature of the study group was the more frequent presence of other autoAbs, among which anti-Ro antibodies were most important. Their presence was associated with SS.Conclusion. …”
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THE FATE OF DYSTOPIAS AND NEOLIBERAL VALUES IN MODERN SERIAL PRODUCTION / СУДЬБА АНТИУТОПИЙ И НЕОЛИБЕРАЛЬНЫЕ ЦЕННОСТИ В СОВРЕМЕННОЙ СЕРИАЛЬНОЙ ПРОДУКЦИИ... by STROEVA OLESYA V. / СТРОЕВА ОЛЕСЯ ВИТАЛЬЕВНА

“…The genre of dystopia is not among the most highly rated, since its character is usually critical and not entertaining. …”
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High-Dose Methotrexate Usage Without Drug-Level Monitoring in Advanced Pediatric Mature B-Cell Non-Hodgkin Lymphoma in a Resource-Limited Setting in Malawi by Rizine R. Mzikamanda, Loviisa Mulanje, Casey L. McAtee, Apatsa Matatiyo, Zoe Mwale, Grace Chirwa, Watipaso Wanda, Atupele Miranda Mpasa, Stella Wachepa, Minke H.W. Huibers, Steve Martin, Tamiwe Tomoka, Maurice Mulenga, Yuri Fedoriw, Gugulethu Mapurisa, Julie M. Gastier Foster, Nader El-Mallawany, Katherine D. Westmoreland, Peter Wasswa, Carl E. Allen, Nmazuo Ozuah

“…With a median follow-up of 14.5 months, 12-month EFS and OS were 45% (95% CI, 32 to 65) and 59% (95% CI, 45 to 79), respectively. Most relapses were stage IV: EFS 20% versus 51% (non–stage IV; P = .057). …”
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