A concept of natural genome reconstruction. Part 2. Effect of extracellular double-stranded DNA fragments on hematopoietic stem cells by V. S. Ruzanova, S. G. Oshikhmina, A. S. Proskurina, G. S. Ritter, S. S. Kirikovich, E. V. Levites, Y. R. Efremov, T. V. Karamysheva, M. I. Meschaninova, A. L. Mamaev, O. S. Taranov, A. S. Bogachev, S. V. Sidorov, S. D. Nikonov, O. Y. Leplina, A. A. Ostanin, E. R. Chernykh, N. A. Kolchanov, E. V. Dolgova, S. S. Bogachev

“…At the same time, treatment with hDNAgr induces proliferation of blood stem cells and their immediate descendants and stimulates colony formation (mouse, rat and humans as the model organisms). Most often, the granulocyte-macrophage lineage of hematopoiesis is activated as a result of processing extracellular double-stranded DNA. …”
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Trends in the annual snow melt-out day over the French Alps and Pyrenees from 38 years of high-resolution satellite data (1986–2023) by Z. Barrou Dumont, Z. Barrou Dumont, S. Gascoin, J. Inglada, A. Dietz, J. Köhler, M. Lafaysse, D. Monteiro, C. Carmagnola, A. Bayle, J.-P. Dedieu, O. Hagolle, P. Choler

“…The SMOD reduction is robust and significant in most parts of the French Alps and can reach 1 month above 3000 <span class="inline-formula">m</span>. …”
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Haploinsufficiency of intraflagellar transport protein 172 causes autism-like behavioral phenotypes in mice through BDNF by Nanxi Zheng, Shilin Luo, Xin Zhang, Ling Hu, Muzhi Huang, Mingyu Li, Colin McCaig, Yu-Qiang Ding, Bing Lang

“…Introduction: Primary cilia are hair-like solitary organelles growing on most mammalian cells that play fundamental roles in embryonic patterning and organogenesis. …”
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Effects of RNA m6A on the formation of multi-petalization in Magnolia wufengensis: Mechanistic insights and gene expression analysis by Cunjie Li, Huarong Li, Jiang Ma, Xiaoning Fan, Yanjun Cai, Liyuan Chen, Hanlin Zhou, Hongwei Liang, Chao Zhou, Faju Chen

“…N6-Methyladenosine (m6A) is the most common modification in the transcriptome of biological RNA and plays roles that include maintaining the stability and transportation of mRNA, mRNA precursor shearing, polyadenylation, and the initiation of translation. …”
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Toxoplasmosis seroprevalence in rheumatoid arthritis patients: A systematic review and meta-analysis. by Zahra Hosseininejad, Mehdi Sharif, Shahabeddin Sarvi, Afsaneh Amouei, Seyed Abdollah Hosseini, Tooran Nayeri Chegeni, Davood Anvari, Reza Saberi, Shaban Gohardehi, Azadeh Mizani, Mitra Sadeghi, Ahmad Daryani

“…RA is an autoimmune disease and the most common type of inflammatory arthritis that is a major cause of disability. …”
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Clinical features of non-compaction cardiomyopathy across age groups: a retrospective study of 415 patients by Ying Li, Jimei Chen, Min Qiu, Miao Tian, Ziqin Zhou, Ruyue Zhang, Jiazichao Tu, Linjiang Han, Shuheng Zhou, Xinming Li, Jian Zhuang, Shusheng Wen

“…Notably, heart failure was most prevalent in adult patients (54.6%, n=53), while cardiac murmur was the primary presenting symptom in both infant and child/adolescent groups (19.5%, n=33 and 17.4%, n=26, respectively). …”
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Nasal Carriage by Staphylococcus aureus among Healthcare Workers and Students Attending a University Hospital in Southern Brazil: Prevalence, Phenotypic, and Molecular Characterist... by Tiago Danelli, Felipe Crepaldi Duarte, Thilara Alessandra de Oliveira, Raquel Soares da Silva, Daniela Frizon Alfieri, Guilherme Bartolomeu Gonçalves, Caio Ferreira de Oliveira, Eliandro Reis Tavares, Lucy Megumi Yamauchi, Marcia Regina Eches Perugini, Sueli Fumie Yamada-Ogatta

“…All MRSAs were distributed into six SCCmec types and type I (62.5%) was the most frequent. REP-PCR typing identified four main clusters among MRSA isolates. …”
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Study on Road Performance and Ice-Breaking Effect of Rubber Polyurethane Gel Mixture by Yuanzhao Chen, Zhenxia Li, Tengteng Guo, Chenze Fang, Jingyu Yang, Peng Guo, Chaohui Wang, Bing Bai, Weiguang Zhang, Deqing Tang, Jiajie Feng

“…Among them, the improvement effect of the KH550 solution was the most significant. With the increase in rubber particle content from 0% to 15%, the dynamic stability of the mixture gradually increases, with a maximum increase of 23.5%. …”
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Framework for Exploration of Statistical Heterogeneity in Multi-Database Studies: A Case Study Using EXACOS-CV Studies by Rhodes KM, Garbe E, Müllerová H, Ekwaru P, Kossack N, Baak BN, Lobier M, Hawkins NM, Nordon C

“…Focus was on adjusted hazard ratios (aHR) for post-exacerbation associations with decompensated heart failure (HF) and all-cause death, for which results were most and least heterogeneous, respectively.Results: Across EXACOS-CV studies, the adjusted hazard ratios (aHR) for HF in the first 1– 7 days post-exacerbation, compared to non-exacerbation periods, ranged from 2.6 (95% CI, 2.3, 2.9) in Germany to 72.3 (64.4, 81.2) in Canada, and the association with death, relative to non-exacerbation periods, ranged from 3.5 (2.4, 5.3) in the Netherlands to 22.1 (19.9, 24.4) in Spain. …”
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Microplastics in human skeletal tissues: Presence, distribution and health implications by Qiaoyi Yang, Ye Peng, Xiaodong Wu, Xiaorui Cao, Peng Zhang, Zhuowen Liang, Jiawei Zhang, Yongfeng Zhang, Peipei Gao, Yunfang Fu, Peng Liu, Zipeng Cao, Tan Ding

“…The average sizes of microplastics in intervertebral discs (159.5 ± 103.8 μm) and bone (138.86 ± 105.67 μm) were larger than that in the cartilage tissue (87.5 ± 30.7 μm). The most frequently identified polymers were polypropylene (35 %), ethylene vinyl acetate copolymer (30 %), and polystyrene (20 %). …”
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Temporal evolution of soil drought stress and its relationship with climate change for tea plantations in the subtropical–warm temperate climate transition zone of China by Zhongdian Zhang, Miao Cai, Songzhu Ye, Tonghui Liu, Mingbin Huang, Wei Zhang, Shuangfeng Jiang, Chong Yao, Junhui Yan, Jiqiang Niu

“…Kuntze) plantation represents one of the most important artificial vegetation types in the subtropical–warm temperate climate transition zone of China. …”
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Associations Between Lifetime Histories of Iron Deficiency, Anxiety, Depression and Multiple Pain Conditions: An Observational Study Using a Large-Scale National Database by Champion D, Bui M, Aouad P, Teng A, Walters AS, Karroum EG, Tan AC, Yang Z, Joyce E, Jaaniste T

“…Iron deficiency, anxiety and depression, as statistical predictors, were univariately and multivariately associated with the number of pain conditions (all p&lt; 0.05).Conclusion: A history of iron deficiency in a community sample of adults was associated with most individual, primary, overlapping and multisite pain conditions tested, and multivariately associated with the number of pain conditions, and with anxiety and depression. …”
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Media Art—XXI Century: Genesis, Art Programs, Education Problems International Scientific Conference / Международная научно-практическая конференция «Медиаискусство XXI век. Генези... by SAZIKOV ALEXEY V. / САЗИКОВ А.В., EVALLYO VIOLETTA D. / ЭВАЛЛЬЁ В.Д.

“…The conference aimed at comprehending the current state of media art in the context of digitalization of classical works and methods of their exposure; at identifying key program and aesthetic dominants in media art; and at systematizing the most relevant educational projects. The organizers suggested the following aspects as the major research focuses: classical arts and media in digital discourse; new media in the socio-cultural environment; current media forms and their genesis; new media in the urban environment; interdisciplinary and authorial projects; educational processes and new competencies. …”
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What is the effect of intergenerational activities on the wellbeing and mental health of children and young people?: A systematic review by Fiona Campbell, Rebecca Whear, Morwenna Rogers, Anthea Sutton, Jane Barlow, Andrew Booth, Andrew Tattersall, Louise Wolstenholme, Joanna Thompson‐Coon

“…Main Results While we identified 500 evaluations of intergenerational interventions, where the impact on participating children and/or young people was evaluated this was most often limited to assessing their impact on attitudes to aging. …”
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Farmers’ environmental perception and adaptation of different livelihood strategies in ecotone: a case of Wanjigou village, Yanchi County, Ningxia by Bian Yingying, Song Naiping

“…Farmers rely on grassland resource and cultivated land resource more and more, and the way that farmers use grassland resource and economic management behaviors has become primary and the most immediate factors which influence the region ecological-environment changes. …”
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Surgical Site Infection Rates in Five Middle Eastern Countries: International Nosocomial Infection Control Consortium Findings by Victor Daniel Rosenthal, Ruijie Yin, Zhilin Jin, Safaa Abdulaziz Alkhawaja, Saleh Fakher Mohamed Sowar, Athraa S.H. Naser, Fatema E.S. Naser, Amani El-Kholy, Victor Bayani, Wafaa Alwakil, Ziad A. Memish

“…However, the following four types of SPs showed SSI rates significantly higher than those of CDC/NHSN: Appendix surgery, 1.8% vs. 1.1% (RR = 1.55, 95% CI: 1.02–2.36; p =0.041); coronary artery bypass, 4.5% vs.1.4% (RR = 3.32, 95% CI: 1.82–6.08; p < 0.001); open reduction of fracture, 2.5% vs. 1.1% (RR = 2.24, 95% CI: 1.50–3.36; p < 0.001); and exploratory abdominal surgery, 3.8% vs. 1.7% (RR=2.30, 95% CI: 1.56–3.39, p < 0.001). Conclusions: Most SSI rates in this set of hospitals in the Middle East are similar to those of CDC/NHSN. …”
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Development of criteria for interpretation and quality assessment of the results of susceptibility testing of Enterobacterales and Pseudomonas aeruginosa to cefepime-sulbactam by Edelstein M.V., Ivanchik N.V., Kozlov R.S.

“…Results. For the two most common Enterobacterales species (E. coli and K. pneumoniae) close values of regression coefficients and good negative correlation of MIC and ZGI values were established (R2 > 0.8). …”
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Assessment of extracellular vesicle microRNAs detection in predicting benign and malignant pulmonary ground glass nodules by Ze Ji, Yufei Xing, Anyuan Zhong, Wensi Li, Suhang Cheng, Xing Pan, Minhua Shi

“…In the healthy group comparison, miR-1-3p remained the most accurate single marker. Specificity ranking: miR-1-3p &gt; miR-20b-5p &gt; miR-92a-2-5p &gt; miR-9-5p &gt; miR-17-5p; sensitivity ranking: miR-1-3p &gt; miR-17-5p &gt; miR-92a-2-5p &gt; miR-20b-5p &gt; miR-9-5p.ConclusionmiR-1-3p, miR-9-5p, miR-17-5p, miR-20b-5p, and miR-92a-2-5p show promise as diagnostic biomarkers for GGN.…”
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Primeras familias diagnosticadas con la enfermedad de Machado Joseph en la población cubana by Yanetza González Zaldívar, Luis E. Almaguer Mederos, José M. Laffita Mesa, Yaimeé Vázquez Mojena, Gilberto Sánchez Cruz, Tania Cruz Mariño, Dany Cuello Almarales, Dennis Almaguer Gotay, Raúl Aguilera Rodríguez, Annelié Estupiñán Rodríguez, Roberto Rodríguez Labrada, Nalia Canales Ochoa, Luis Velázquez Pérez

“…ABSTRACT   Backgrounds: Machado-Joseph disease (MJD/SCA3) is an inherited neurodegenerative disease due to the expansion of CAG repeats in the ATXN3 gene. It is the most prevalent spinocerebellar ataxia worldwide, but so far no cases had been diagnosed in Cuba. …”
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The genetic history of Portugal over the past 5,000 years by Xavier Roca-Rada, Roberta Davidson, Matthew P. Williams, Vanessa Villalba-Mouco, António Faustino Carvalho, Shyamsundar Ravishankar, Evelyn Collen, Christian Haarkötter, Leonard Taufik, Daniel R. Cuesta-Aguirre, Catarina Tente, Álvaro M. Monge Calleja, Rebecca Anne MacRoberts, Linda Melo, Gludhug A. Purnomo, Yassine Souilmi, Raymond Tobler, Eugénia Cunha, Sofia Tereso, Vítor M. J. Matos, Teresa Matos Fernandes, Anne-France Maurer, Ana Maria Silva, Pedro C. Carvalho, Bastien Llamas, João C. Teixeira

“…Abstract Background Recent ancient DNA studies uncovering large-scale demographic events in Iberia have presented very limited data for Portugal, a country located at the westernmost edge of continental Eurasia. Here, we present the most comprehensive collection of Portuguese ancient genome-wide data, from 67 individuals spanning 5000 years of human history, from the Neolithic to the nineteenth century. …”
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