Splenic macrophage functional profile and its role in the immunopathogenesis of canine visceral leishmaniasis by Tainã Luís de Souza, Tainã Luís de Souza, Marta de Almeida Santiago, Francini Neves Ribeiro, Francini Neves Ribeiro, Fabiano Borges Figueiredo, Artur Augusto Velho Mendes Junior, Rodrigo Caldas Menezes, Renato Porrozzi, Fernanda Nazaré Morgado

“…Immunological markers were analyzed via immunohistochemistry, immunofluorescence, and flow cytometry.ResultsSplenic white pulp disorganization was observed in most animals, indicating marked tissue disruption. …”
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COMPARATIVE ANALYSIS OF TISSUE EXERTION OF MUCOUS MEMBRANES DURING DIFFERENT STAGES OF TENSION IN PERFORMING ON CLOTTING OPERATION by D.V. Kaplun, V.M. Skrupnik, S.O. Stavitsky

“…In our opinion, it is important to study the morphological properties of the mucous membranes of the oral cavity and optimal tensions and tissue stresses in the area of suturing. It is known that the most susceptible to the action of mechanical factors area is the mucous membrane of the gums. …”
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Epidemiological aspects of nephrolithiasis and chronic diseases of the cardiovascular system combination by R. V. Royuk, S. K. Yarovoy, N. A. Guseva, Sh. L. Voskanyan, V. V. Royuk, D. B. Rodin

“…Congestive heart failure occurred among 153 patients (20,9%); most often it occurred among patients from III – in 102 cases (35,2%). …”
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Platelet specific knockout of integrin beta-3 (β3) reduces severity of necrotizing enterocolitis in murine neonates by Marie Amalie Balamurugan, Marie Amalie Balamurugan, Balamurugan Ramatchandirin, Balamurugan Ramatchandirin, Suneetha Desiraju, Arjun Subrramanya, Juanitaa George Raj, Megan M. Ferris, Megan M. Ferris, Zainab D. Lawal, Oluwabunmi O. Olaloye, Liza Konnikova, Liza Konnikova, Liza Konnikova, Liza Konnikova, Liza Konnikova, Liza Konnikova, Krishnan MohanKumar, Krishnan MohanKumar, Krishnan MohanKumar, Krishnan MohanKumar

“…IntroductionNecrotizing Enterocolitis (NEC) is the most impactful gastrointestinal disease of premature neonates and preclinical evidence shows that the event of platelet activation is an important pathophysiological contributor during NEC-like injury in murine neonates. …”
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Fantasias da igualdade: uniformes escolares e democratização no Brasil by Katiene Nogueira da Silva, Denice Barbara Catani

“…Palavras-chave: uniformes escolares - democratização do ensino - práticas escolares - periódicos educacionais - cultura escolar Fantasies of equality: school uniforms and democratization in Brazil Abstract The article examines the different configurations of the school uniforms use practices in the period 1948-1971, in Brazil. Awakening the most diverse sentiments, intending to "clear differences" socio-economic evidenced by the clothes and trying to make "all the same" by the requirement of a single type of clothing, school uniforms were a source of pride, of intimidation or sign of distinction. …”
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Pre-hospital assessment of trauma associated severe hemorrhage (phTASH) – analysis of TraumaRegister DGU® data from 2015-2021 by Christoph Jänig, Willi Schmidbauer, Erwin Kollig, Tobias Gruebl, Rolf Lefering, Lisa Hackenberg, Daniel C. Schroeder, Dan Bieler, Committee on Emergency Medicine, Intensive Care, Trauma Management (Sektion NIS) of the German Trauma Society (DGU)

“…A logistic regression analysis is used to identify the items of both scores with the highest impact on the predictive quality of each score. The items with the most influence were then combined to form the new prehospital Trauma Associated Severe Hemorrhage (phTASH) score. …”
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Out-of-pocket expenditure and financial risks associated with treatment of chronic kidney disease in Ethiopia: a prospective cohort costing analysis by Ole Frithjof Norheim, Solomon Tessema Memirie, Mizan Habtemichael, Hamelmal G Hailegiorgis, Leja Hamza Juhar, Tsegay Berhane, Sisay Tesfaye, Workagegnehu Hailu Bilchut, Maekel Belay Woldemariam, Lina Mohammed Ahmedtaha

“…Introduction In Ethiopia, most healthcare expenditures are paid out-of-pocket (OOP), while the burden of kidney disease (KD) is rapidly increasing, posing a major public health challenge in low- and middle-income countries, along with a staggering economic burden. …”
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Unique Stress, Cultural Resources, and Psychological Resilience in Young African American Women: Insights for Effective Intervention and CVD Prevention by Sparkle Springfield-Trice, Cara Joyce, Penny Williams-Wolford, Dinishia Wolford, Destiny Onyeise, Natalie Battles, Dionne V. Milton, Chineze Mogbo, Raigine Robinson, Dave Stovall, Lena Hatchett, Ursula M. Staudinger

“…We employed linear regression to examine the relationships among stressors, resources, and resilience, and then used elastic net (EN) regularization to identify the resources most strongly associated with resilience after adjusting for age and stressors. …”
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Borderline personality disorder Athens study: a quasi-experimental pragmatic trial for the assessment of a public, psychodynamic, stepped care service for borderline personality di... by Ioannis Malogiannis, Lida Anagnostaki, Maria Aspradaki, Panagiotis Aristotelidis, Katerina Karambela, Maria Amperiadou, Vasiliki Efthymiou, Phaithra Kriezi, Ioanna Theodoridou, Pentagiotissa Stefanatou, Pentagiotissa Stefanatou, George Konstantakopoulos, George Konstantakopoulos, Kyriakos Souliotis, Lily E. Peppou, Eleni Giannoulis, Eleni Giannoulis

“…Although psychotherapy is recommended as the most effective treatment for patients with BPD, their complex emotional needs can be met in everyday clinical practice by developing integrative, holistic, personalized mental health services tailored to their needs.Aim and hypothesisThe aim of our study was to evaluate the effectiveness of a specialized psychodynamic stepped-care service for BPD patients. …”
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Comorbidity Disease Pattern in Japanese Elderly Population: A Network-Based Analysis by Shuko Nojiri, PhD, Wataru Urasaki, MSc, Masao Iwagami, MD, PhD, Masashi Nagao, MD, PhD, Takuya Uematsu, MSc, Muneaki Ishijima, MD, PhD, Hiroyuki Daida, MD, PhD, Yuji Nishizaki, MD, PhD

“…Conclusion: In this study, we identified major comorbidity patterns and reported that atherosclerosis, angina pectoris, gastritis, and duodenitis were the most important comorbid diseases in the elderly population in Japan. …”
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Monitoring of Vaccination Adherence among Healthcare Workers in the Russian Federation by R. V. Polibin, A. Ya. Mindlina, N. I. Briko, V. A. Korshunov, A. S. Avagyan, V. S. Butenkova

“…The vast majority of medical workers (94.4% ± 0.2%) recommend vaccination to their friends and relatives, most this applies to vaccinations against measles, hepatitis B, diphtheria, tetanus, and to a lesser extent – against infections against which vaccination is not included in the National Immunization Schedule. …”
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Acute targeting of N-terminal tau protein has long-lasting beneficial effects in Tg2576 APP/Aβ mouse model by reducing cognitive impairment, cerebral Aβ-amyloidosis, synaptic remod... by Valentina Latina, Margherita De Introna, Francesca Malerba, Rita Florio, Bijorn Omar Balzamino, Giuseppe Di Natale, Michele Francesco Maria Sciacca, Giuseppe Pappalardo, Alessandra Micera, Annabella Pignataro, Pietro Calissano, Giuseppina Amadoro

“…This enduring beneficial effect on memory deficit (up to 90 days after the last injection) is accompanied by normalization in the synaptic imbalance and microgliosis along with decrease of the most toxic A11-positive prefibrillar oligomers and inverse increase in 4kDa monomeric form(s) of Aβ 1–42. …”
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Standardization of tree species in agroforestry systems of Coffea arabica L. at different altitudes in Amazonas, Peru by Nixon Haro, Gerson Meza-Mori, Jaqueline Llomeli Zuta Lopez, Elí Pariente, Heyton Deyvi Garcia Cruz, Lily Juarez-Contreras, Elver Coronel Castro, Rosalynn Yohanna Rivera Lopez, Manuel Oliva-Cruz

“…For the analysis, Random Forest was used to determine the importance of the variables, followed by the TOPSIS method to prioritize the most suitable species at each altitude. At low altitudes, Mespilodaphne quixos and Psidium guajava presented canopy cover of 21 % and 35 %, pH of 6.04 and 5.56, and yields above 80 %. …”
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Evolutionary history and association with seaweeds shape the genomes and metabolisms of marine bacteria by Catherine A. Pfister, Johanna Berlinghof, Maximiliana Bogan, Ulisse Cardini, Angélique Gobet, Pauline Hamon-Giraud, Jessica Hart, Natalia Jimenez, Anne Siegel, Emma Stanfield, Marine Vallet, Catherine Leblanc, Coralie Rousseau, François Thomas, Willem Stock, Simon M. Dittami

“…In particular, Flavobacteriia showed the most pronounced differences between host-associated and free-living strains. …”
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Altered albumin/neutrophil to lymphocyte ratio are associated with all-cause and cardiovascular mortality for advanced cardiovascular-kidney-metabolic syndrome by Xiaoshuang Yin, Jinmei Zou, Jing Yang

“…This method identifies the optimal cutoff for continuous variables where the difference in survival rates is most pronounced, making it particularly well-suited for analyzing time-to-event data, such as survival outcomes. …”
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Radiomics with Clinical Data and [¹⁸F]FDG-PET for Differentiating Between Infected and Non-Infected Intracavitary Vascular (Endo)Grafts: A Proof-of-Concept Study by Gijs D. van Praagh, Francine Vos, Stijn Legtenberg, Marjan Wouthuyzen-Bakker, Ilse J. E. Kouijzer, Erik H. J. G. Aarntzen, Jean-Paul P. M. de Vries, Riemer H. J. A. Slart, Lejla Alic, Bhanu Sinha, Ben R. Saleem

“…The best-performing models for the <i>MAGIC-light</i> features and <i>PET-radiomics</i> features were selected from 343 unique models. Most relevant features were combined to test three final models using ROC analysis, accuracy, sensitivity, and specificity. …”
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Identification and Expression Analysis of the ADH Gene Family in Chinese Pepper(Capsicum chinense) by Chu YE, Wei LIN, Chuan WANG, Bingchun XIE, Xiaowan XU, Xiaomei XU, Hengming WANG, Junheng LYU, Minghua DENG, Zhiming WU, Tao LI, Zhou HENG

“…【Objective】Capsicum chinense is a member of the Solanaceae family and Capsicum genus, most of which have a rich fruity aroma produced by branched-chain esters. …”
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A comprehensive integrated disease management program for phenylketonuria (IDMP-PKU) from Türkiye: rationale, design and patient characteristics by Mehmet Cihan Balci, Deniz Kor, Yilmaz Yildiz, Meryem Karaca, Fatma Derya Bulut, Ayca Burcu Kahraman, Alihan Yesil, Ezgi Burgac, Kismet Ciki, Arzu Selamioglu, Burcu Koseci, Asli Durmus, Irem Kaplan, Esra Kara, Halise Neslihan Mungan, Serap Sivri, Gulden Fatma Gokcay, Aysegul Tokatli, Mubeccel Demirkol, Turgay Coskun, Imran Ozalp

“…Parental consanguinity was reported in 43.5% of families (27.1% first cousins). The most frequently detected allelic variant was c.1066-11G > A (IVS-10-11G > A) (22.8%). …”
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The association between sexually transmitted infections and pregnancy outcomes in the Northern Territory, Australia: a population-based cohort studyResearch in context by Jennifer Dunne, Gizachew A. Tessema, Matthew Legge, Sylvester Dodzi Nyadanu, Aditi Roy, Amanuel T. Gebremedhin, Jacqueline Hendriks, Tricia Reid-Moore, Gavin Pereira

“…Interpretation: STIs during pregnancy showed notable associations with adverse birth outcomes. Congenital syphilis most severely affected outcomes, tripling preterm birth risk and doubling small-for-gestational age risk. …”
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Evaluation of Anti-HPV18 Antibody Titers Preceding an Incident Cervical HPV18/45 Infection by Fanua Wiek, Viswanathan Shankar, Ana Gradissimo, Angela Diaz, Ligia A. Pinto, Nicolas F. Schlecht, Robert D. Burk

“…<b>Results:</b> Antibody titers for HPV18 were most different between AYW who developed an HPV18/45 infection compared to high-risk controls OR = 1.66, 95% CI: 0.96–2.85 (<i>p</i> = 0.1629). …”
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