Optimization of a culture medium for Bacillus subtilis based on monosodium glutamate wastewater by LIU Li, ZENG Zhen, FANG Ping

“…However, the main ingredients of medium used in most of these studies were peptone, yeast extracts, beef extracts, soy or corn flour, associated with great cost and excessive consumption of resources.The purpose of this study was to investigate a cost-effective resource utilization of CMGW by increasing the density of B. subtilis F-2 viable cells in cultures. …”
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A novel IgG-based FLT3xCD3 bispecific antibody for the treatment of AML and B-ALL by Melanie Märklin, Gundram Jung, Jonas S Heitmann, Joseph Kauer, Helmut R Salih, Stefanie Mueller, Bochong Li, Latifa Zekri, Naveen K Mehta, Martin Pfluegler, Kristan Meetze, Isabelle Sindel, Fabian Vogt, Lukas Osburg, Hans-Jörg Bühring, Sebastian Hörner, Patrick A Baeuerle, Jennifer S Michaelson

“…However, such immunotherapeutic strategies are not yet established for acute myeloid leukemia (AML), the most common form of acute leukemia in adults. Common targets in AML such as CD33, CD123, and CLEC12A are highly expressed on both AML blasts and on normal myeloid cells and hematopoietic stem cells (HSCs), thereby raising toxicity concerns. …”
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Urban human-elephant conflict in Zimbabwe: a case study of the mitigation endeavour by Aliénor Scrizzi, Sébastien Le Bel, Mike La Grange, Daniel Cornélis, Cheryl Mabika, René Czudek

“…Results from a soft-systems analysis showed that only a few bulls were responsible for most of the incursions. The elephants fed at any opportunity and displayed enough behavioural flexibility and innovative behaviours to thrive in an urban setting. …”
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The limitations of mobile phone data for measuring movement patterns of populations at risk of malaria by Greta Tam, Ipsita Sinha, Kulchada Pongsoipetch, Keobouphaphone Chindavongsa, Mayfong Mayxay, Sonexay Phalivong, Benjamin J. Cowling, Olivo Miotto, Supaporn Mahaphontrakoon, Saiamphone Xayvanghang, Richard J. Maude

“…Descriptive analysis was performed, and logistic regression with weights on aggregate data was used to compare the demographic distribution of mobile phone ownership and use in malaria patients with that in the general population. Results Most patients with malaria (76%) did not own or use a mobile phone. …”
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Tang Bi formula alleviates diabetic sciatic neuropathy via AMPK/PGC-1α/MFN2 pathway activation by Cunqing Yang, Honghai Yu, Linfeng Zhou, Hang Su, Xiangyan Li, Wenxiu Qi, Fengmei Lian

“…Abstract Diabetic peripheral neuropathy (DPN) is one of the most common chronic complications of diabetes mellitus, which affects various regions of the nervous system. …”
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Trends of cholera epidemics and associated mortality factors in Cameroon: 2018–2023: a cross-sectional study by Akenji Blaise Mboringong, Sen Claudine Henriette Ngomtcho, Roland Ndip Ndip, Esso Endalle Linda, Dibog Luc Bertand, Mendjime Patricia, Belinga Sandrine, Balana Flore Essiene, Theodore Ntamack, Etoundi Georges Alain Mballa

“…The three coastal regions (Littoral, South and South-West Region) reported 83.4% (15,839/18,986) of all the cases while the remaining five affected regions jointly reported 16.6% (3,147/18,986) cases. The most represented age group were those aged 25–35 years (21.9%; 4,163/1,876) and the male: female sex ratio was 1.27. …”
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The Construction of an Intrauterine Diagnosis and Treatment System and Comprehensive Lifecycle Health Service of Congenital Heart Disease: Xinhua Hospital Model by Shiwei Jiang, Jiajun Ye, Hualin Wang, Jian Wang, Sun Chen, Yongjun Zhang, Qing Du, Ling Yang, Lei Wang, Kun Sun

“…Congenital heart disease (CHD), as one of the most common congenital birth defects, is the leading cause of mortality in patients aged <5 years, and brings a heavy burden to both the affected families and society. …”
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Nomogram for predicting the severity of high-risk plaques in acute coronary syndrome by Miao-Na Bai, Miao-Na Bai, Miao-Na Bai, Ji-Xiang Wang, Ji-Xiang Wang, Xiao-Wei Li, Xiao-Wei Li, Xiao-Wei Li, Jing-Xian Wang, Jing-Xian Wang, Yu-Hang Wang, Yu-Hang Wang, Yin Liu, Yin Liu, Yin Liu, Jing Gao, Jing Gao, Jing Gao, Jing Gao

“…A nomogram was created, and the receiver operating characteristic curve was used to assess the model's discrimination, as well as the bootstrap method to internally validate it.ResultsThe most commonly observed HRP characteristic was lipid plague &gt;180° (147 patients), followed by MLA &lt; 3.5 mm2 (141 patients), macrophages (127 patients), and FCT &lt; 75 μm (64 patients). …”
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Association of artificial intelligence–predicted milk yield residuals to behavioral patterns and transition success in multiparous dairy cows by C. Kemel, M. Salamone, B. Aernouts, I. Adriaens, G. Opsomer, P. Hut, M. Hostens

“…Rumination time in the 21 d after calving was lower in the category with the most negative milk yield residuals (low MRT) compared with both the other categories, with differences up to 36.12 min (95% CI: 24.63–47.62 min), while standing times after calving were highest in the low MRT category. …”
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Evaluación de la actividad física en estudiantes universitarios de la Amazonía peruana: Un estudio transversal (Assessment of physical activity in university students from the Peru... by Jimmy Nelson Paricahua-Peralta, Edwin Gustavo Estrada-Araoz, Yony Abelardo Quispe-Mamani, Libertad Velasquez-Giersch, Alhi Jordan Herrera-Osorio, Dany Dorian Isuiza-Perez, Nelly Jacqueline Ulloa-Gallardo, Elizabeth Orfelia Cruz-Laricano

“…It was concluded that most university students in the Peruvian Amazon engaged in moderate levels of physical activity. …”
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Bionomics and distribution of malaria vectors in Kisumu city, Western Kenya: implications for urban malaria transmission by Maxwell G. Machani, Shirley A. Onyango, Irene Nzioki, Sylvia Milanoi, Godfrey Nattoh, John Githure, Harrysone Atieli, Chloe Wang, Ming-Chieh Lee, Goufa Zhou, Andrew K. Githeko, Yaw A. Afrane, Eric Ochomo, Guiyun Yan

“…In urban areas, all An. funestus s.l. samples were An. funestus s.s. . Most (55.5%) of Anopheles mosquitoes were collected indoors, while secondary vectors were mainly outdoors. …”
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High‐Efficiency Carriers’ Separation Strategy Based Ultrasmall‐Bandgap CuWO4 Sono‐Enhances GSH Antagonism for Cuproptosis Cascade Immunotherapy by Lichao Zhu, Zhisheng Guo, Yu Luo, Haiyan Huang, Kexin Zhang, Bingbing Duan, Renmiao Peng, Haochen Yao, Chao Liang, Kaiyang Wang

“…Abstract The spatiotemporal sequential treatment strategy of promoting rapid separation of charge carriers, amplifying oxidative stress, increasing the low content of intracellular Cu, enhancing cuproptosis, and cascading activation of immunotherapy is considered one of the most effective techniques for improving the comprehensive therapy of tumors. …”
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Microbial mineralization combined with vegetation soil stabilization in coal mining subsidence areas by Ying GAO, Tao LI, Kaidan ZHENG, Limin FAN, Ruhong BAI, Qiang SUN

“…The research results indicate that: ① Coal mining has the most significant impact on soil moisture content, with a 7.7% decrease in moisture content in the severely disturbed area (D1) compared to the slightly disturbed area (D0). …”
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Life cycle assessment of facile applicable biodiesel production by Mohamed A. Hanafy, Rehab M. Ali, Abdallah S. Elgharbawy, Ahmed I. Osman, Mohamed A. Farrag, Abdulaziz H. Al-Anazi

“…Herein, this approach represents a life cycle assessment (LCA) of biodiesel production from waste cooking oil (WCO) utilizing potassium carbonate (K2CO3) as a heterogeneous catalyst instead of potassium hydroxide (KOH), which is the most used catalyst in industry. However, KOH requires a 20% methanol and a 66% reaction time, higher than K2CO3. …”
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True- and pseudo-mitral annular disjunction in patients undergoing cardiovascular magnetic resonance by Kamil Stankowski, Federica Catapano, Dario Donia, Renato Maria Bragato, Pedro Lopes, João Abecasis, António Ferreira, Leandro Slipczuk, Pier-Giorgio Masci, Gianluigi Condorelli, Marco Francone, Stefano Figliozzi

“…In all measurements, systolic MAD extent (2.3 [1.7–3.0] mm) resulted equal to or greater than diastolic MAD extent (2.0 [1.5–2.9] mm). The most frequent MAD location was the inferior wall (117/290, 40%) and the inferolateral wall was the rarest (50/290, 17%). …”
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Genome‐wide prediction of synthetic rescue mediators of resistance to targeted and immunotherapy by Avinash Das Sahu, Joo S Lee, Zhiyong Wang, Gao Zhang, Ramiro Iglesias‐Bartolome, Tian Tian, Zhi Wei, Benchun Miao, Nishanth Ulhas Nair, Olga Ponomarova, Adam A Friedman, Arnaud Amzallag, Tabea Moll, Gyulnara Kasumova, Patricia Greninger, Regina K Egan, Leah J Damon, Dennie T Frederick, Livnat Jerby‐Arnon, Allon Wagner, Kuoyuan Cheng, Seung Gu Park, Welles Robinson, Kevin Gardner, Genevieve Boland, Sridhar Hannenhalli, Meenhard Herlyn, Cyril Benes, Keith Flaherty, Ji Luo, J Silvio Gutkind, Eytan Ruppin

“…Abstract Most patients with advanced cancer eventually acquire resistance to targeted therapies, spurring extensive efforts to identify molecular events mediating therapy resistance. …”
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West Palaearctic species of Euura Newman, 1837 (Hymenoptera, Tenthredinidae) by Marko Prous, Andrew Liston, Spencer K. Monckton, Katja Kramp, Hege Vårdal, Veli Vikberg, Erik Heibo, Marko Mutanen

“…Strong mito-nuclear discordance is observed within most species groups, but in some cases even between species groups. …”
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Modulating effect of glutathione (GSH) on 2,4-dichlorophenoxyacetic acid (2,4-D) toxicity by Marzena Matejczyk, Edyta Juszczuk-Kubiak, Paulina Średnicka, Piotr Ofman, Grażyna Łaska, Krzysztof Kurek, Kavindra Kumar Kesari, Ruslan Oblap, Józefa Wiater, Paweł Kondzior, Monika Kalinowska

“…Abstract 2,4-dichlorophenoxyacetic acid (2,4-D) is a chlorinated aromatic hydrocarbon herbicide and one of the most widely used herbicides globally. Due to the intensive use of 2,4-D, mainly in agriculture and horticulture, significant amounts of the compound and its metabolites are released into the environment, surface water and soil, posing a serious threat to human health. …”
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Viral suppression and continued participation in the Community Retail Pharmacy Drug Distribution Point model among people living with HIV in Uganda by Paul Lwevola, Rodgers Katwesigye, Derrick Kimuli, Happy Annet Walusaga, Ibrahim Twinomujuni, Joan Nangendo, Immaculate Ddumba, Fred Ntuuyo, Sheila Kyobutungi, Samuel Kawuma, Moses Arinaitwe, Fred C. Semitala

“…Results The mean age of the participants was 43.5 (± 9.8) years, most participants were female (62.2%) and married (53.9%). …”
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Investigating the Factors Influencing Behavioral Intention and Adoption of Artificial Intelligence Technology: A Case Study of Cultivation and Industries at Razavi Agricultural Com... by A. Sani Heidary, E. Safari

“…However, this sector is facing many challenges in recent years. Some of its most important challenges include the increasing growth of the world's population, a 40% reduction in water and soil resources, the destruction of a quarter of agricultural land, climate change, a lack of specialized labor, poor access to financial resources, strict laws, and a decrease in the number of farmers due to a decrease in motivation. …”
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