Study of local inflammatory response in different clinical forms of chronic polypous rhinosinusitis by E. A. Varyushina, E. V. Bezrukova, E. V. Vorobeychikov, E. V. Kravchenko, J. V. Sukhareva, M. A. Aflitonov, A. S. Simbirtsev

“…These disorders lead to a decrease in muco-ciliary clearance in nasal cavity. The most significant pathomorphological changes occur in CRSwNP + BA, especially in cases of asthmatic triad. …”
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Impact of the COVID‐19 pandemic on the performance of endoscopy in the Tohoku region of Japan by Katsunori Iijima, Tamotsu Matsuhashi, Yosuke Shimodaira, Tatsuya Mikami, Tetsuro Yoshimura, Shunichi Yanai, Norihiko Kudara, Tsuyotoshi Tsuji, Hiro‐o Matsushita, Hiroyuki Watanabe, Tomoyuki Koike, Katsuaki Kato, Yasuhiko Abe, Nakao Shirahata, Takuto Hikichi, Kyoko Katakura, Koji Kono, Hirotake Sakuraba, Yoshiyuki Ueno, Hiromasa Ohira, Atsushi Masamune, Takayuki Matsumoto, Shinsaku Fukuda, Japan Gastroenterological Endoscopy Society‐Tohoku

“…Conclusions This is the most comprehensive survey on the impact of the COVID‐19 pandemic on the performance of endoscopy and the resulting diagnosis of cancer in Japan. …”
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THE ROLE OF BRAF MUTATION STATUS IN SURGICAL TREATMENT OF WELL-DIFFERENTIATED THYROID CANCER by A. P. Polyakov, N. N. Volchenko, E. N. Slavnova, A. V. Kudryavtseva, M. V. Ratushnyy, V. V. Ratushnaya, M. M. Filyushin, I. V. Rebrikova, P. A. Nikiforovich

“…Mutation of the BRAF gene (V600E) is one of the most common prognostic factors for PTC. Various studies showed different degree of correlation between BRAF (V600E) mutation and other prognostic factors.Materials and methods. 60 patients with PTC treated in P.A. …”
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The application of artificial intelligence in upper gastrointestinal cancers by Xiaoying Huang, Minghao Qin, Mengjie Fang, Zipei Wang, Chaoen Hu, Tongyu Zhao, Zhuyuan Qin, Haishan Zhu, Ling Wu, Guowei Yu, Francesco De Cobelli, Xuebin Xie, Diego Palumbo, Jie Tian, Di Dong

“…Upper gastrointestinal cancers, mainly comprising esophageal and gastric cancers, are among the most prevalent cancers worldwide. There are many new cases of upper gastrointestinal cancers annually, and the survival rate tends to be low. …”
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Perioperative pain management in thoracic surgery and side effects in the early postoperative period by H. B. Poniatovska, S. O. Dubrov, P. L. Poniatovskyi, S. O. Sereda, M. V. Denysiuk, S. V. Cherniaiev, А. О. Kotliar

“…The frequency of complications in MA group was 10.8 % of the total number of patients, in TEA group – 12.7 %, PA – 6.4 %, and in C group – 8.9 %. The most common complaint among TEA group patients was injection-site itching (13.5 %). …”
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Brugada syndrome in the forensic field: what do we know to date? by Oscar Campuzano, Oscar Campuzano, Oscar Campuzano, Simone Grassi, Estefanía Martínez-Barrios, Estefanía Martínez-Barrios, Estefanía Martínez-Barrios, Andrea Greco, Andrea Greco, Andrea Greco, Vincenzo Arena, Georgia Sarquella-Brugada, Georgia Sarquella-Brugada, Georgia Sarquella-Brugada, Georgia Sarquella-Brugada, Georgia Sarquella-Brugada, Antonio Oliva

“…Deleterious variants in the SCN5A gene are the most common cause of Brugada syndrome; however, the genetic diagnostic yield of Brugada Syndrome remains low, with a deleterious variant in SCN5A identified in only a 25%–30% of cases, and a high number of phenotype-positive genotype-negative individuals. …”
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Dietary Patterns of Serbian Adults 10–74 Years Old: Serbian National Food Consumption Survey Following EU Menu Methodology by Jelena Milešević, Milica Zeković, Ivana Šarac, Marija Knez, Irena Krga, Vuk Stevanović, Mirjana Gurinović

“…Results: In the adult population, quantitatively, the most consumed foods are as follows: vegetable and vegetable products (312 g/day), milk and milk products (247.7 g/day), fruit and fruit products (245.7 g/day), grain and grain products (215.8 g/day), and meat and meat products (166.08 g/day). …”
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Transannular bovine jugular vein monocusp for the reconstruction of severe right ventricular outflow tract obstructionCentral MessagePerspective by Luigi Di Pasquale, MD, Olivia Jaeger, MD, Tugba Erdil, MD, Martin Christmann, MD, Daniel Quandt, MD, Robert Cesnjevar, MD, Hitendu Dave, MD

“…Five needed catheter interventions: supravalvar stent (2), LPA stent (3), and RPA stent (1), most of them in the earlier half of the experience. …”
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THE EFFICACY OF HIGH-DOSE CONSOLIDATION AND AUTOLOGOUS BONE MARROW TRANSPLANTATION IN FIRST REMISSION OF ACUTE MYELOID LEUKEMIA by I. A. Samorodova, S. N. Bondarenko, V. N. Ovechkina, A. V. Klimovich, E. I. Podolceva, N. V. Medvedeva, A. S. Nizamutdinova, E. V. Karyagina, B. I. Smirnov, I. S. Moiseev, L. S. Zubarovskaya, B. V. Afanasyev

“…Introduction. The question of the most adequate treatment strategy of AML in cases when it is impossible to perform allogeneic HSCT because of any reason still remains open.The aim of this study was to assess the long-term survival of patients with AML who received chemotherapy (CT) or autologous HSCT as consolidation in the first remission of the disease. …”
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Divergent WNT signaling and drug sensitivity profiles within hepatoblastoma tumors and organoids by Thomas A. Kluiver, Yuyan Lu, Stephanie A. Schubert, Lianne J. Kraaier, Femke Ringnalda, Philip Lijnzaad, Jeff DeMartino, Wouter L. Megchelenbrink, Vicky Amo-Addae, Selma Eising, Flavia W. de Faria, Daniel Münter, Marc van de Wetering, Kornelius Kerl, Evelien Duiker, Marius C. van den Heuvel, Vincent E. de Meijer, Ruben H. de Kleine, Jan J. Molenaar, Thanasis Margaritis, Hendrik G. Stunnenberg, Ronald R. de Krijger, József Zsiros, Hans Clevers, Weng Chuan Peng

“…Abstract Hepatoblastoma, the most prevalent pediatric liver cancer, almost always carries a WNT-activating CTNNB1 mutation, yet exhibits notable molecular heterogeneity. …”
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INFLUENCE OF CERTAIN D-METALS ON FORMATION OF ADVANCED GLYCATION END PRODUCTS, AGGREGATION AND AMYLOID TRANSFORMATION OF ALBUMIN IN GLYCATION REACTION by R. A. Litvinov, A. V. Gontareva, L. E. Usmiyanova, D. R. Klimenko

“…Among such ions as nickel (II), cobalt (II), iron (II), iron (III), copper (II) and zinc (II), copper (II) ions turned out to be the most active in their ability to accelerate the AGEs formation, suppress the fluorescence of tryptophan and tyrosine, enhance the aggregation and amyloid transformation of BSA in the glycation reaction. …”
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Characteristics and driving factors of power generation performance in microbial fuel cells: an analysis based on the CNKI database by Ruikai Zhang, Wentao Dai, Hongyong Xiang, Hongyong Xiang, Hongyong Xiang, Jie Chen, Jie Chen, Jie Chen, Ting Yi, Jiayi Li, Jiebin Zhang, Qiuxi Yang, Rui Xiao, Xiang Li

“…Microbial fuel cells (MFCs) have become one of the most promising technologies in the field of ecology and environmental science due to their dual functions of power generation and pollutant removal. …”
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A novel framework for esophageal cancer grading: combining CT imaging, radiomics, reproducibility, and deep learning insights by Muna Alsallal, Hanan Hassan Ahmed, Radhwan Abdul Kareem, Anupam Yadav, Subbulakshmi Ganesan, Aman Shankhyan, Sofia Gupta, Kamal Kant Joshi, Hayder Naji Sameer, Ahmed Yaseen, Zainab H. Athab, Mohaned Adil, Bagher Farhood

“…Radiomic features were classified into four reliability levels based on their ICC (Intraclass Correlation) values. Most of the features had excellent (ICC > 0.90) or good (0.75 < ICC ≤ 0.90) reliability. …”
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Predictive nomogram model for severe coronary artery calcification in end-stage kidney disease patients by Xinfang Tang, Hanyang Qian, Shijiu Lu, Hui Huang, Jing Wang, Fan Li, Anning Bian, Xiaoxue Ye, Guang Yang, Kefan Ma, Changying Xing, Yi Xu, Ming Zeng, Ningning Wang

“…In the four branches of the coronary arteries, LAD calcification is the most common. Our validated nomogram model, based on clinical risk factors, can help predict the risk of severe coronary calcification in ESKD patients who cannot undergo coronary CT analysis.…”
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Assessing water requirements and suitability for apple growth at county scale in China: a phenological modeling approach during key growth stages by Xiaoya Ru, Xiaoya Ru, Xiaoya Ru, Tianzhi He, Tianzhi He, Guochao Yan, Guochao Yan, Yong He, Yong He, Zhujun Zhu, Zhujun Zhu, Qiang Yu, Jianqiang He

“…Despite the fruit expansion stage having the highest average water requirement (319 mm), multi-year data indicated ‘relatively suitable’ (S=0.8) conditions for most counties. In contrast, although the average water requirement during flowering-fruit setting was 120 mm, the suitability level was classified as ‘unsuitable’ (S=0.3), indicating a water shortage, particularly in Xinjiang, the northwest Loess Plateau, and northern Bohai Bay areas. …”
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Accurate prediction of damage depth of multi-story structural footings with Matlab implementation by Ang LI, Weidong WANG, Qian MOU, Feng WANG, Zhenghe MA, Lei ZHAO, Gang HUANG, Yonggen ZHOU, Shengqi TIAN

“…The results show that ① most of the working conditions in the calculation of the damage depth of multilayer structure base plate need to be solved by Taylor expansion and quadratic equation several times, and the manual calculation process is long and complicated, which is very likely to lead to deviations in the calculation results; ② by comparing the maximum damage depth of the base plate under the same working condition with the same parameters by manual calculation and machine calculation (Matlab built-in function), it can be seen that with the increase of the number of layers of the base plate, the manual solution process leads to the maximum damage depth of the base plate due to the repeated application of Taylor expansion. ③ The main interface of the software contains the number of layers, layer thickness, mechanical parameters, input boxes, calculation buttons, etc., which can quickly and intelligently identify the working conditions and calculate the maximum depth of damage of the bottom slab and the maximum depth of damage from the mining face to the bottom slab. ④ will be a mine of flat coal related lithological mechanical parameters into the software solution, by comparing and analyzing the five-layer structure of the maximum depth of destruction of the base plate theoretical value, fitting value, measured value and software value can be seen, the theoretical value and measured results deviation of 0.57 m, software value and measured value of the difference of 0.14 m, the results of multi-layer calculations under the software calculations are more in line with the actual needs, can be for the bottom of the board of the prevention and control of water hazards and safety of mining to provide a reliable technology parameter.…”
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Risk factors of immune-related endocrine toxicities in non-small cell lung cancer patients treated with pembrolizumab and its impact on patient outcomes: a multicenter retrospectiv... by Haoting Zhang, Jing Zheng, Chenyi Ren, Chenlin Ye, Xiaoyu Wu, Xiaodong Lv, Yuping Li, Jianya Zhou, Jianying Zhou

“…Among these events, immune-related endocrine toxicities (E-irAE) represents the most common form, though their etiology, risk factors, and impact on patient outcomes remain poorly understood. …”
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The image of a “Special” Tree and its Transformation in the Space of a South Korean TV Series / Образ «особенного» дерева и его трансформации в пространстве южнокорейского телесери... by TARASOVA ALEKSANDRA V. / ТАРАСОВА А.В.

“…Further, I address contemporary television series of various genres, mostly fantasy. Most of the examples are united by one particular tree, which, since 2005, has “starred” in more than twenty TV series. …”
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Prevalence of Germline Variants in Advanced Renal Cell Carcinoma in North India by Chitrakshi Nagpal, Mohit Kumar Divakar, Hemavathi Baskarane, Ghazal Tansir, Rishabh Jain, Aparna Sharma, Ranjit Kumar Sahoo, Sameer Bakhshi, Ishaan Gupta, Shilpi Minocha, Saran Kumar, Pranay Tanwar, Brusabhanu Nayak, Rishi Nayyar, Sridhar P, Seema Kaushal, Sanjay Ojha, Parnika Nangla, Kunhi Parambath Haresh, Amlesh Seth, Atul Batra

“…Fumarate hydratase was the most common RCC-associated variant (2.8%), while WT1, BRCA1, BRIP1, and ATM (1.4% each) were the commonest non–RCC-associated variants. …”
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Methicillin‐resistant Staphylococcus aureus and Pseudomonas aeruginosa community acquired pneumonia: Prevalence and locally derived risk factors in a single hospital system by Bradley W. Frazee, Amarinder Singh, Matt Labreche, Partow Imani, Kevin Ha, Jonathan Furszyfer Del Rio, Eugene Kreys, Robert Mccabe

“…Thus, the prevalence P. aeruginosa and MRSA was 2.9% in the overall CAP cohort, but 30.3% in the microbiologically confirmed cohort. The most important predictors of either P. aeruginosa or MRSA isolation were tracheostomy (odds ratio [OR] 22.08; 95% confidence interval [CI] 10.39–46.96) and gastrostomy tube (OR 14.7; 95% CI 7.14–30.26). …”
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