Perfil empreendedor de docentes do curso de enfermagem de uma universidade pública [Enterprising profile of teachers of the nursing course at a public university] [Perfil emprended... by Cassieli Beatrice Tossin, Larissa Gutierrez de Carvalho da Silva, Mariana Ângela Rossaneis, Maria do Carmo Fernandez Lourenço Haddad

“…Results: the interviewees’ tendency to be enterprising was medium to high and, among those who scored high, need for autonomy was the dimension most prevalent in the analysis. Scores were low in the calculated risk taking dimension. …”
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Antioxidant supplementation boosts the advantages of CrossFit workouts on oxidative and muscle damage markers in obese males by Morteza Nemati, Neda Bozorgtabar, Maha Hoteit, Zahra Sadek, Abdullah Almaqhawi, Ali Rashidy-Pour, Nematollah Nemati, Mohammad Rashidi, Niloofar Karimi, Mitra Khademosharie, Reza Bagheri, Ayoub Saeidi, Maisa Hamed Al Kiyumi, Katie M. Heinrich, Hassane Zouhal

“…Abstract Supplementing with antioxidants may be one of the most efficient means of minimizing oxidative stress during workouts in obese individuals. …”
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Development and validation of a 20 K genome-wide liquid SNP array for Chinese mitten crab (Eriocheir sinensis) breeding and germplasm identification by Yulin Bai, Zhou Jiang, Junlei Ma, Yidong Liang, Ting Zhang, Anqi Wang, Changsui Hu, Dongpo Xu

“…The GWAS analysis for four growth traits (BW, BH, CL, and CW) identified 46 significant SNPs associated with CL. Among these, the most significant SNP (chr46_1686249) is located within a 100 Kb upstream and downstream region that contains three candidate genes: ptpn11, profilin-1, and lei. …”
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Prevalence of, and Factors Associated with Hemodynamic Instability Among Women Presenting with Incomplete Abortion at a Tertiary Hospital in Southwestern Uganda by Kakama C, Agaba DC, Byamukama O, Kajabwangu R, Kengonzi E, Akol MA, Muhumuza A, Businge J, Turanzomwe S, Ainomugisha B, Kalyebara KP, Kayondo M, Ngonzi J, Muganwa WG, Lugobe HM

“…Caxton Kakama,1 David Collins Agaba,2 Onesmus Byamukama,3 Rogers Kajabwangu,1,3 Elizabeth Kengonzi,1 Mathiang Agany Akol,1 Amos Muhumuza,1 Julius Businge,1 Stuart Turanzomwe,1 Brenda Ainomugisha,1 Kato Paul Kalyebara,1 Musa Kayondo,1 Joseph Ngonzi,1 Wasswa George Muganwa,3 Henry Mark Lugobe1 1Department of Obstetrics and Gynecology, Mbarara University of Science and Technology, Faculty of Medicine, Mbarara, Uganda; 2Department of Physiology, Mbarara University of Science and Technology, Faculty of Medicine, Mbarara, Uganda; 3Department of Obstetrics and Gynecology, Mbarara Regional Referral Hospital, Mbarara, UgandaCorrespondence: Caxton Kakama, Department of Obstetrics and Gynaecology, Mbarara University of Science and Technology, Faculty of Medicine, Mbarara, 1410, Uganda, Tel +256 777465000, Email doncaxt@gmail.comBackground: Sub-Saharan Africa has a high abortion case-fatality rate, and most of these maternal deaths are due to hemodynamic instability which results from hemorrhage, especially in cases of incomplete abortion. …”
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Polymorphisms in NLRP1 Gene Are Associated with Type 1 Diabetes by Xiaoxiao Sun, Ying Xia, Yue Liu, Yanfei Wang, Shuoming Luo, Jian Lin, Gan Huang, Xia Li, Zhiguo Xie, Zhiguang Zhou

“…Additionally, the polymorphism rs11651270 was also related to T1D in an additive model (OR=0.719, 95% CI=0.583-0.887). Most importantly, when we analyzed the clinical characteristics of T1D individuals with different genotypes, we found that the age of onset with the TT genotype at rs11651270 was younger than those with the other two genotypes (p=0.001). …”
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Identifying Patients’ Preference During Their Hospital Experience. A Sentiment and Topic Analysis of Patient-Experience Comments via Natural Language Techniques by Yuan J, Chen X, Yang C, Chen J, Han P, Zhang Y, Zhang Y

“…The analysis of free-text comments can add value to quantitative measures by offering information which matters most to patients and by providing detailed descriptions of the service issues that closed-ended items may not cover.Objective: To extract useful information from large amounts of free-text patient experience comments and to explore differences in patient satisfaction and loyalty between patients who provided negative comments and those who did not.Methods: We collected free-text comments on a broad, open-ended question in a cross-sectional patient satisfaction survey. …”
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Adaptive cohort design and LAT1 expression scale: study protocol for a Phase 2a trial of QBS72S in breast cancer brain metastases by Rukayat Taiwo, Paul M. Harary, Thy T. H. Trinh, Monica Granucci, Sophie Bertrand, Brandon Carlson-Clarke, Sophia B. Chernikova, Kate Therkelsen, Mili Arora, Michelle E. Melisko, Michael Iv, Hannes Vogel, Summer Han, Christine Xie, Susie Brain, Vivian Lee, Krishna L. Bharani, Seema Nagpal, Melanie Hayden Gephart

“…Abstract Background Breast cancer is the most common cause of cancer death among women and frequently metastasizes to the brain. …”
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Clinical validation of controlled exposure to cat dander in the Specialized Particulate Control Environmental Exposure Unit (SPaC-EEU) by Lubnaa Hossenbaccus, Sophia Linton, Sarah Garvey, Hannah Botting, Terry Walker, Lisa Steacy, Anne K. Ellis

“…Abstract Background Cat allergen is the second most common cause of perennial allergic rhinitis. …”
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The Osteoarthritis Thumb Therapy (OTTER) II Trial: a study protocol for a three-arm multi-centre randomised placebo controlled trial of the clinical effectiveness and efficacy and... by Michael Doherty, Rachael Gooberman-Hill, Susan Dutton, Peter White, Nigel K Arden, Mark Williams, Jo Adams, Paula Barratt, Sofia Barbosa Bouças, Sarah Bradley, Krysia Dziedzic, Kelly Hislop Lennie, Corinne Hutt Greenyer, Victoria Jansen, Ramon Luengo-Fernandez, Claire Meagher

“…Symptomatic thumb base OA affects 20% of people over 55 years, causing more pain, work and functional disability than OA elsewhere in the hand. Most evidence-based guidelines recommend splinting for hand OA. …”
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Study of the Role of the Tumor Microenvironment in Ovarian Cancer (MICO): A Prospective Monocentric Trial by Martina Arcieri, Eleonora Capezzali, Stefano Restaino, Sara Pregnolato, Laura Mariuzzi, Alessandro Mangogna, Maria Orsaria, Angelica Tulisso, Silvia Tonon, Maria De Martino, Miriam Isola, Lorenza Driul, Carlo Pucillo, Giovanni Scambia, Barbara Frossi, Giuseppe Vizzielli

“…ABSTRACT Background Ovarian cancer (OC) is one of the most aggressive tumors requiring new therapeutic approaches. …”
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Effects of Different Interventions Using Taekwondo, Boxing, and Elastic Band Training on Body Composition and Physical Function in Chilean Older Women: A Randomized Controlled Tria... by Edgar Vásquez-Carrasco, Jordan Hernandez-Martinez, Izham Cid-Calfucura, Eduardo Guzmán-Muñoz, Camila Ruiz, Camila Baeza, María José Márquez, Tomás Herrera-Valenzuela, Braulio Henrique Magnani Branco, Eduardo Carmine-Peña, Paulina Sepúlveda, Cristian Sandoval, Pablo Valdés-Badilla

“…<b>Conclusions</b>: Although no substantial differences were observed between groups for most variables, TKD and BOX interventions significantly reduced Timed Up-and-Go times, whereas EBT enhanced maximal isometric handgrip strength in both hands. …”
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RNF20/RNF40 supports the aggressive behavior in cervical cancer by regulating a peroxisome-based anti-ferroptotic mechanism by Shaishavi Jansari, Anna Blandau, Evangelos Prokakis, Daniela Grimm, Anja Maria Naßl, Stefan Küffer, Wiebke Möbius, Christian Dullin, Fernanda Ramos-Gomes, Leona Schüürhuis, Lena Fritsche, Laura Schridde, Matthias Plessner, Carolin. A. Bast, Fabian A. Gayer, Sven Thoms, Julia Gallwas, Florian Wegwitz

“…Abstract Background Cervical cancer is the fourth most common cancer entity in women worldwide. Currently, malignant lesions are clinically managed by surgery, conventional chemotherapy, and/or radiotherapy. …”
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Robot-assisted laparoscopic ureteropelvic junction plasty in children using the da Vinci Xi robotic system: a Russian first experience by V. V. Sizonov, A. G. Makarov, S. M. Pakus, D. G. Kvaratskhelia, E. V. Orlova, S. G. Piskunova, M. I. Kogan

“…Robotic pyeloplasty represents the most frequently performed surgical intervention globally utilizing the da Vinci robotic platform in pediatric patients. …”
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DETECTION OF SOMATIC MUTATIONS IN THE BRAF GENE BY PYROSEQUENCING by O. P. Dribnokhodova, E. A. Dunaeva, G. V. Leshkina, E. A. Yarygina, A. Yu. Bukharina, Ya. A. Voiciehovskaya, E. V. Borisova, S. K. Bormotova, A. I. Daoud, V. N. Khlavich, K. O. Mironov

“…Extraction of DNA from clinical samples obtained by fine-needle aspiration biopsy in most cases provided a sufficient concentration of DNA, which made it possible to use the technique in combination with cytological analysis without additional sampling. …”
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A prospective cluster randomized trial of an interventions bundle to reduce inappropriate antibiotic use for upper respiratory tract infections in the outpatient setting by Adeel A. Butt, Sherin Shams, Atika Jabeen, Asma Ali Al-Nuaimi, Jeyaram Illiayaraja Krishnan, Aimon B. Malik, Samah Saleem, Maryam Hassan Abdulaziz, Naheel Ismail Seyam, Kamran Aziz, Dalia Kandil, Anil G. Thomas, Hanaa Nafady-Hego, Muzna I. Lone, Jameela Al Ajmi, Zain A. Bhutta, Noora AlSulaiti, Wael E. Said Hussein, Sandy Semaan, Samya Ahmad Al-Abdulla, Mohamed Ghaith Al-Kuwari, Abdul-Badi Abou-Samra

“…The relative drop in inappropriate antibiotic prescriptions before and after the interventions was 16.3% (42.4% vs 35.5%; p < 0.001) at intervention sites (p < 0.001) compared with 2.2% (45.9% to 44.9%; p = 0.4) at control sites. Senior-most physicians and younger population (19–40 years old) were more likely to prescribe or receive inappropriate antibiotic prescription. …”
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Revisiting Neutrophil-to-lymphocyte Ratio and De Ritis Ratio as Glycemic Control Assessment Tool among Type 2 Diabetes Mellitus: A Retrospective Study by Asharani Ningappa, Mahanth Nagaraju

“…Results: Out of 120 subjects, 52.5% (<i>n</i> = 63) were in the age-group of 40–60 years and most of them (68.25%) had poor glycemic control with a mean HbA1c level of 10.0 ± 1.5 %. …”
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Ischemic heart disease burden attributable to inadequate omega-3 fatty acid intake in Chinese adults, 1990–2021: an Age-Period-Cohort analysis of the Global Burden of Disease study... by Lin Luo, Lin Luo

“…Net drift analysis showed that the annual decline in DALY rate (−1.53%) was significantly greater than the death decline (−0.32%), with the most notable improvement in the middle-aged group (local drift of −3.87% per year).ConclusionThis study is the first to reveal the dynamic evolution of IHD burden attributable to insufficient omega-3 intake in China. …”
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COMPARATIVE ANALYSIS OF DIFFERENT NEOADJUVANT CHEMOTHERAPY REGIMENS FOR TRIPLE-NEGATIVE BREAST CANCER by P. V. Krivorotko, E. K. Zhiltsova, L. P. Gigolaeva, Sh. M. Khadzhimatova, G. A. Dashyan, K. Yu. Zernov, E. S. Trufanova, А. S. Artemyeva, A. G. Kudaibergenova, V. F. Semiglazov

“…Triple-negative breast cancer (TNBC) is one of the most aggressive subtypes characterized by high sensitivity to chemotherapy and early recurrence. …”
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Application of machine learning algorithm for prediction of abortion among reproductive age women in Ethiopia by Angwach Abrham Asnake, Alemayehu Kasu Gebrehana, Hiwot Altaye Asebe, Beminate Lemma Seifu, Bezawit Melak Fente, Meklit Melaku Bezie, Mamaru Melkam, Sintayehu Simie Tsega, Yohannes Mekuria Negussie, Zufan Alamrie Asmare

“…According to the SHAP beeswarm and bar plots, younger age was identified as the strongest predictor of abortion, with a mean SHAP value of + 0.060. The second most impactful factor was having a younger husband, contributing a mean SHAP value of + 0.050 to abortion prediction in Ethiopia. …”
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Comparing recovery community centers (RCCs) serving Black, Hispanic/Latino, and other communities: an exploratory secondary data analysis of a nationwide survey of RCC directors by Diadora DeCristofaro, Allison Futter, Alivia Williamson, Susanne S. Hoeppner, Lauren A. Hoffman, Marion J. Riggs, Judeline Joseph, Julia Ojeda, Amy A. Mericle, Vinod Rao, Philip X. Rutherford, Patty McCarthy, Bettina B. Hoeppner

“…RCCs differed in offering 12-step mutual aid groups (lowest in RCCs serving Hispanic/Latino communities; p = 0.03) and the existence of direct collaboration with clinical sites providing medications for opioid use disorder (MOUD, most common in RCCs serving Black communities; p = 0.03).ConclusionThe overall RCC model appears to be consistent across racial/ethnic settings in terms of footprints, model of care, services offered, connection to relevant systems and organizations, and attitudes toward medications. …”
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