Correlation analysis between facial feature-based traditional Chinese medicine inspection of spirit classification and Beck Depression Inventory score by Shan Lu, Xubo Shang, Dong Yang, Junfeng Yan, Xiaoye Wang

“…Further exploration using association rule mining identified the most compelling rule: “moderate depression (Q3) → Shenluan”. …”
Get full text

Paxlovid for the treatment of severe or critical COVID-19 in children by Linjuan Xiang, Qun Wang, Yanwen Xu, Yu Tong, Yuhang Wu, Xiaoshan Zhang, Xinxin Zeng, Sheng Ye, Chenmei Zhang, Linhua Tan, Lvchang Zhu, Jing Miao, Sun Chen, Xi Zhang, Xuben Yu, Lisu Huang

“…The Paxlovid group showed a significantly shorter time to viral clearance, fever resolution, and symptom recovery compared to controls (4.9 vs. 11.0 days, P = 0.01; 11.2 vs. 16.4 days, P = 0.01; 4.6 vs. 17.6 days, P < 0.01). This effect was most noticeable in children with underlying conditions or those treated early. …”
Get full text

Impact of Relaxation and Music Intervention on Psychological and Gastrointestinal Health in Military Recruits: A Prospective Study by Liu J, Liu T, Lu H, Zhao X, Ma S, Song F, Qiao N, Cheng W, Qi X

“…The proportions of severe (P&lt; 0.001) and mild (P&lt; 0.001) constipation evaluated by the BSFS decreased after intervention, but those of severe (P=0.632) and mild (P&lt; 0.001) diarrhea evaluated by the BSFS increased.Conclusion: Short-term progressive muscular relaxation training in combination with music intervention is potentially effective for most gastrointestinal symptoms, but not for diarrhea, in recruits.Keywords: gastrointestinal symptom, psychology, anxiety, depression, music intervention, progressive muscular relaxation training, intervention…”
Get full text

Behavioral, physiological and genetic responses of the Yesso scallop Mizuhopecten yessoensis to the predation of sea star by Xuetao Li, Xuetao Li, Xuetao Li, Xian Li, Xian Li, Danyang Li, Danyang Li, Dandan Zhang, Xingyue Zhai, Xubo Wang, Xubo Wang, Junxia Mao, Junxia Mao, Ying Tian, Ying Tian, Ming Liu, Yaqing Chang, Yaqing Chang, Zhenlin Hao, Zhenlin Hao

“…Enzyme assays indicated significant changes in superoxide dismutase (SOD), catalase (CAT), arginine kinase (AK), and octopine dehydrogenase (ODH) across different tissues and size groups, with the most pronounced responses observed in medium - sized individuals. …”
Get full text

Commensal and virulent Escherichia coli strains of vaginal origin are reservoirs of resistance cassettes in class 1 integrons by Manalli Itzahaya Blancarte–Lagunas, Graciela Castro-Escarpulli, Armando Navarro-Ocaña, Gabriela Ibáñez-Cervantes, Laura Margarita Marquez-Valdelamar, José Misael Hernández-Carrillo, Juana Salazar-Salinas, Omar Fernando Mendoza-Vásquez, Gabriel Damazo-Hernández, Oscar Sosa-Hernández, Gregorio León-García, Monica Alethia Cureño-Díaz, Juan Manuel Bello-López

“…Phylogenetic group A was the most predominant, followed by group B2 and D. …”
Get full text

Assessment of Knowledge, Awareness and Attitudes about the Risk of Periodontal Disease among Polycystic Ovarian Disease Patients Residing in Chennai, India: A Questionnaire based C... by S Varsha, Jai Santhosh Manikandan, Makesh Raj, Sai Krishna, Hemalatha, Nanda Kumar, Pravina Fernando

“…Introduction: Polycystic Ovarian Disease (PCOD) has become one of the most prevalent conditions among females of reproductive age. …”
Get full text

Susceptibility and shedding in Mx1+ and Mx1− female mice experimentally infected with dairy cattle A(H5N1) influenza virusesResearch in context by Asim Biswas, Amie J. Eisfeld, Lizheng Guan, Chunyang Gu, Tong Wang, Hassanein H. Abozeid, Hua Shi, Sanja Trifkovic, Peter J. Halfmann, Gabriele Neumann, Yoshihiro Kawaoka

“…PWK/PhJ mice, which were selected for their natural expression of Mx1, better reflect the antiviral capacity of most wild house mice, whereas BALB/cJ mice lack functional Mx1. …”
Get full text

Key quality dimensions for gluten-free bread perceived by general and non-gluten consumers: A case study with apple pomace and flaxseed by Leire Cantero-Ruiz de Eguino, Jesús Salmerón, Monica Ojeda, Francisco José Perez-Elortondo, Iñaki Etaio, Edurne Simón, Jonatan Miranda, Olaia Martinez

“…Results showed that the formulations containing up to 6 % apple pomace and 12 % flaxseed resulted in the most acceptable products for both consumers group. …”
Get full text

Immunomics-guided biomarker discovery for human liver fluke infection and infection-associated cholangiocarcinoma by Lakkhana Sadaow, Rutchanee Rodpai, Michael J. Smout, Rie Nakajima, Patcharaporn Boonroumkaew, Javier Sotillo, Bemnet A. Tedla, Vor Luvira, Amnat Kitkhuandee, Krisada Paonariang, Wattana Sukeepaisarnjaroen, Hiroshi Yamasaki, Sutas Suttiprapa, Thewarach Laha, Banchob Sripa, Rafael de Assis, Aarti Jain, Wannaporn Ittiprasert, Victoria H. Mann, Yide Wong, Philip L. Felgner, Wanchai Maleewong, Paul J. Brindley, Alex Loukas, Pewpan M. Intapan

“…We incorporate two of the most promising antigens from the proteome array screen, P1 and P9, into PoC-ICTs to further validate their diagnostic performance. …”
Get full text

A 3D acid fracturing design calibrated to describe the productivity index in several southwestern Iranian oil fields by Mohammad Mirhashemi, Kaveh Ahangari, Ali Naghi Dehghan, Kamran Goshtasbi

“…By assessing these input parameters, the study aims to optimize the conditions under which acid fracturing can be most effective. This provides valuable insights into the design and implementation of acid treatments in reservoir engineering. …”
Get full text

Rhinoceros from the Middle Stone Age in the Eastern and Western Cape of South Africa by Shaw Badenhorst, Rialivhuwa Ratshinanga, Francesca Parrini, Karen L van Niekerk, Christopher S Henshilwood

“…All sites contain individual specimens of rhinoceros; however most faunal assemblages yielded only a few isolated specimens (201 specimens in total, representing 5% of the total sample). …”
Get full text

Deep learning-based prediction of individualized Real-time FSH doses in GnRH agonist long protocols by Na Kong, Yu Xia, Zhilong Wang, Hui Zhang, Liyan Duan, Yingchun Zhu, Chenyang Huang, Guijun Yan, Jie Mei, Wujun Li, Haixiang Sun

“…Abstract Background Individualizing follicle-stimulating hormone (FSH) dosing during controlled ovarian stimulation (COS) is critical for optimizing outcomes in assisted reproduction but remains difficult due to patient heterogeneity. Most existing models are limited to static predictions of initial doses and do not support real-time adjustments throughout stimulation. …”
Get full text

Risk Factors for Multidrug-resistant Tuberculosis by Cleopas Martin Rumende

“…A review of the published literature strongly suggest that the most powerful predictor for the presence of MDR-TB is a history of TB treatment. …”
Get full text

Low Dose Cytarabine and Cladribine for Treatment of Relapsed or Refractory Acute Myeloid Leukemia: Clinical Experience by SV Gritsaev, II Kostroma, AA Kuzyaeva, IM Zapreeva, EV Litvinskaya, LV Stel’mashenko, SA Tiranova, IS Martynkevich, NA Potikhonova, KM Abdulkadyrov

“…Response was achieved in 5 patients: 2 patients achieved complete response (CR) and 3 achieved partial response (PR). The most common complication was hematologic toxicity. …”
Get full text

Association of epigenetic aging with plasma biomarkers of amyloid, tau, neurodegeneration, and neuroinflammation in Hispanic/Latino adults by Myriam Fornage, Wassim Tarraf, Martha L. Daviglus, Charles DeCarli, Kevin A. Gonzalez, Carmen R. Isasi, Sayaka Kuwayama, Melissa Lamar, Bonnie E. Levin, Humberto Parada, Alberto R. Ramos, Tatjana Rundek, Bharat Thyagarajan, Hector M. González

“…The second‐generation clock PC-PhenoAge showed strong and consistent associations across all biomarkers, and thus may reflect biological processes most relevant to age-related changes in AD biomarkers. …”
Get full text

EstablishINg the best STEp-up treatments for children with uncontrolled asthma despite INhaled corticosteroids (EINSTEIN): protocol for a systematic review, network meta-analysis a... by Ian Sinha, Dyfrig A Hughes, Michelle Maden, Stephen Turner, Sofia Cividini, Sarah Donegan, Giovanna Culeddu, Katie Rose, Olive Fulton, Catrin Tudur Smith

“…We will perform an IPD-NMA—eventually supplemented with aggregate data for the RCTs without IPD—to establish both the probability that a treatment is best and the probability that a particular treatment is most likely to be effective for a specific profile of the patient. …”
Get full text

Androgen Deprivation Therapy–Induced Muscle Loss and Fat Gain Predict Cardiovascular Events in Prostate Cancer Patients by Jie Lee, Yi‐Hsuan Lin, Pai‐Kai Chiang, Jhen‐Bin Lin, Ya‐Ting Jan, Wei‐Kung Tsai, Yu‐Jen Chen, Kun‐Pin Wu

“…The ΔSMI and ΔSATI were the most important features for predicting MACE in both cohorts, whereas ΔVATI and baseline body composition parameters were less influential. …”
Get full text

Combinations of polymorphisms in the regulatory regions of cytokine genes are associated with diabetic retinopathy in type 2 diabetic patients by V. I. Konenkov, A. V. Shevchenko, V. F. Prokof`ev, V. V. Klimontov, N. V. Tyan, V. V. Chernykh, D. V. Chernykh, A. V. Eremina, A. N. Trunov

“…In the combinations associated with DR with a specificity &gt;99% homozygous GG genotype in position -174 of IL6 (rs1800795), CT genotype in position -31 of IL1B (rs1143627), СС genotype in position -592 of IL10 (rs1800872), CT genotype in position -590 of IL4 (rs2243250) were the most frequently detected variants. High levels of HbA1c (&gt;9.8%) were associated with combinations of CA genotype in position -863 TNFA (rs1800630) with homozygous variants GG in positions -238 and -308 TNFA (rs1800629, rs361525).Conclusion. …”
Get full text

Factors associated with the intermediate probability of heart failure with preserved ejection fraction on the H₂FPEF score in asymptomatic patients in rotation work cond... by A. S. Vetoshkin, N. P. Shurkevich, A. A. Simonyan, L. I. Gapon, M. A. Kareva

“…Based on the odds ratio (OR) analysis, the factor most strongly influencing the intermediate probability of HFpEF was BMI (OR=1,261, 95% confidence interval (CI): 1,140-1,393). …”
Get full text

Planting Strategy Optimization Can Increase Maize Yield by Delaying Leaf Senescence and Improving Photosynthetic Capacity by Li Zhao, Xinrong Duan, Xinping Zhang, Xin Zhang, Linzhuan Song, Pei Chen, Min Liang, Chang Zhang, Chuangyun Wang

“…The interaction effect between two intercropping maize factors significantly affects corn yield, with a medium density of 67,500, where 6000 is the most effective. Thus, 67,500 plants/hm² combined with a row spacing of 40 + 80 cm significantly increases corn yield. …”
Get full text