Perspectives of non‐physician partners on barriers and facilitators to AYA cancer care in Latin America by Samantha L. Wong, Elysia Alvarez, Emily E. Johnston, Crystal Romero, Nuria Rossell, Ligia Rios, Wendy Gómez García, Federico Antillon‐Klussmann, Ligia Fu, Soad Fuentes‐Alabi, Karina Quintero Delgado, Daniel Ortiz Morales, Carolina Rodriguez‐Loza, Salvador A. Lopez, Melissa Gosdin, Marcio Malogolowkin, Paola Friedrich

“…Although successful treatment of cancer in AYA has increased in recent years in most of the world, this is not true for many low‐ and middle‐income countries (LMIC) where over 80% of all AYA live. …”
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AAV-shDUX4 provides short-term benefits but limited long-term efficacy in a DUX4 mouse model of FSHD by S. Sohn, S. Reid, M. Bowen, C. Hudon, E. Corbex, B. Morel, C. Hourde, V. Mariot, J. Dumonceaux

“…However, by 10 months post-treatment, the therapeutic effects had substantially diminished, with most pathological markers remaining uncorrected and no sustained improvement in muscle force. …”
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Evaluación agroindustrial de los aceites esenciales de Artemisia dracunculos L, Franseria artemisioides Willd, Salvia officinalis L, Lippia dulcis Frev, y Occimun americanum L en c... by Luis F Saldarriaga C, Ginna M Sánchez M, Carmen Rosa Bonilla Correa, Manuel Salvador Sánchez Orozco, Harlen Gerardo Torres Castañeda

“…The biggest yields of oil essential were presented in the leaves in all the species; were the most representative chemical compounds the Elemicina (40.11%) in Tarragon, b-Himachaleno (53.98%) in Marco, trans -b- Cariofileno (22.18) in Kitchen sage, a- Bisabolol (15.79%) in Aztec sweet herb and 1,8- Cineol (Eucaliptol) (23.34%) in Lime basil. …”
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Screening for atrial fibrillation with or without general practice involvement: a controlled study by Rakesh N. Modi, Efthalia Massou, Peter H. Charlton, Andrew Dymond, Kate Williams, James Brimicombe, Ben Freedman, Simon J. Griffin, F. D. Richard Hobbs, Gregory Y. H. Lip, Richard J. McManus, Jonathan Mant

“…The remainder received administrator-led screening: 81 were automatically given a consultation; 74 were offered a consultation, and 74 were not offered a consultation. Most screened participants (280/288, 97.2%) recorded ≥ 56 adequate-quality ECGs. …”
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Realismo y antirrealismo en la concepción semántica de las teorías científicas by León Olivé

“… Bas van Fraassen, one of the most energetic defenders of the semantic conception of scientific theories, has recently held that while scientific theories can be identified through their models they cannot be identified with them (van Fraassen [1985], cf. this volume). …”
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Randomized Trial of Pegmolesatide for the Treatment of Anemia in Patients With Nondialysis CKD by Jianteng Xie, Aicheng Yang, Hongyu Qiu, Xiaomei Peng, Wanhong Lu, Xiangyang Huang, Qinkai Chen, Aimin Zhong, Shuifu Tang, Qin Wang, Chuan Li, Liangliang He, Xiaohong Jia, Anran Ma, Fan Wang, Xueqing Yu

“…The incidence of adverse events (AEs) and serious AEs (SAEs) were similar between groups, with hypertension being the most reported AE related to the study drug. No drug-related hypersensitivity reactions or fatal events were observed. …”
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Evaluación de la fractura por fatiga del cigüeñal de un motor Diesel. // Evaluation of the crank shaft fatigue failure of a boat diesel engine. by R. A. Goytisolo Espinosa, J. G. Noa Águila, N. Arzola de la Peña, L. Castellanos González, H. Hernández Herrera, L. López Torres, A. Fernández Cañizares

“…The fatigue security factors in some<br />of the most critical areas of the cheek, where the failure took place, are lower than unity. …”
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The Number of Metastatic Lymph Nodes is a Useful Predictive Factor for Recurrence after Surgery for Nonmetastatic Nonfunctional Neuroendocrine Neoplasm of the Pancreas by G. Capretti, G. Nappo, V. Smiroldo, M. Cereda, B. Branciforte, P. Spaggiari, S. Carrara, P. Preatoni, F. Gavazzi, C. Ridolfi, G. Donisi, A. Lania, A. Zerbi

“…The number of metastatic lymph nodes and mitotic count is the most significant predictive factors of recurrence after pancreatic surgery for nonmetastatic nonfunctioning pNENs.…”
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The Effectiveness of the Combination of Bay Leaf Extract (Syzygium polyanthum) and Celery Leaf Extract (Apium graveolans L.) on Lowering Blood Sugar Level in Wistar Rats (Rattus no... by Diva Erita Laorenz, Yandri Naldi, Friska Oktavrisa

“…Conclusion: The combination of bay leaf extract and celery leaf extract at a dose of 300 mg/kgBW is most effective in reducing blood glucose levels in hyperglycemic Wistar rats. …”
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Prognostic impact of gene alterations via homologous recombination DNA repair gene alteration status in pancreatic ductal adenocarcinoma by Yusuke Kawanaka, Chiaki Inagaki, Chiaki Inagaki, Masaki Okura, Seiichiro Mitani, Takayuki Takahama, Takayuki Takahama, Kimio Yonesaka, Kimio Yonesaka, Yasutaka Chiba, Kazuhiko Nakagawa, Hisato Kawakami, Hisato Kawakami, Hidetoshi Hayashi

“…BackgroundPancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies, with limited treatment options and poor prognosis. …”
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Los patrones de diseño como herramientas para guiar la práctica del profesorado / The design patterns as tools to guide the practice of teachers by Begoña Gros, Anna Escofet, Marta Marimón­-Martí

“…Although research on the pedagogical patterns are scare, in recent years a lot of effort have been done analysing the most appropriate methodologies for processing and the development of systems of formalization that can reach a common representation language teaching patterns. …”

Differential roles of interleukin-6 and adrenomedullin in early diagnosis and mortality predictions in late-onset neonatal sepsis by Emilly Henrique dos Santos, Gabriel Acca Barreira, Mariana Okay Saippa, Maria Carolina Pires Cruz, Karen Alessandra Rodrigues, Ronaldo Arkader, Thelma Suely Okay

“…Results Coagulase-negative Staphylococcus was the most commonly detected pathogen. ADM (cutoff, 0.5 ng/mL) and CRP (cutoff, <5 mg/L) values aligned with manufacturer recommendations, while IL-6 levels (cutoff, 10 pg/mL) were higher than expected, likely due to labor stress. …”
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The Century of Authoritarianism (Analysis of the Characteristics and Forms of Authoritarianism in the 21st Century by Moslem Karamzadi

“…Repression, mass arrests, and executions are rarely used, and most citizens do not experience direct state violence. …”
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Deep well as a facility for on-line hydraulic studies of the stress state of the rock mass in fluid-saturated fractured reservoirs by A. G. Vakhromeev, V. M. Ivanishin, S. A. Sverkunov, V. N. Polyakov, R. K. Razyapov

“…Thestress state with significantly changing permeability parameters of filtering fractures is among the most complex states of stress [Belonin et al., 2005; Borevsky, 1986]. …”
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Footprint in fitting $$B\rightarrow D$$ B → D vector form factor and determination for D-meson leading-twist LCDA by Sheng-Bo Wu, Hai-Jiang Tian, Yin-Long Yang, Wei Cheng, Hai-Bing Fu, Tao Zhong

“…In the TFF, D-meson leading-twist light-cone distribution amplitude (LCDA) is the most important non-perturbative input parameter, the precise behavior of which is mainly determined by the parameter $$B_{2;D}$$ B 2 ; D in the light-cone harmonic oscillator model. …”
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THE STUDY "REGISTER OF PATIENTS AFTER ACUTE STROKE (REGION)." Part 1. Hospital Prospective Register of Patients after Acute Stroke (According to the Results of the Pilot Phase of t... by S. A. Boytsov, S. Yu. Martsevich, N. P. Kutishenko, M. M. Loukianov, A. E. Mitichkin, R. V. Viskov, L. V. Stakhovskaya, N. A. Shamalov, G. P. Arutyunov, I. V. Kokareva, N. E. Parsadanyan, M. I. Chernyshova, A. V. Zagrebelnyy, N. A. Dmitrieva, A. V. Akimova, G. I. Nikitina, O. V. Lerman, V. P. Voronina, E. N. Belova, E. N. Kudryashov, A. D. Deev

“…Data on the risk factors of CVD and their complications were reflected insufficiently in the medical records. Most patients in the prehospital period did not receive adequate treatment for the reduction in the cardiovascular risk. 90 patients survived and were discharged. 1.5-2 years after discharge, information on the vital status was available for 78 (86.7%) patients. 61 of them (78.2%) were alive and 17 (21.8%) died. …”
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Analysis of early use of everolimus with low-dose calcineurin inhibitors in kidney transplant recipient by I. G. Kim, N. A. Tomilina, I. V. Ostrovskaya, I. A. Skryabina, N. D. Fedorova

“…The 4-year survival rate of the method of everolimus treatment was 57.2%, and the event-free graft survival rate was 47.9%. The most frequent causes of everolimus withdrawal were rejection (25.8% of all causes), proteinuria (19%), progressive graft dysfunction (16, 1%) and adverse events (16.1%). …”
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A Comprehensive Review on the Pharmacokinetics and Drug&amp;minus;Drug Interactions of Approved GLP-1 Receptor Agonists and a Dual GLP-1/GIP Receptor Agonist by Min JS, Jo SJ, Lee S, Kim DY, Kim DH, Lee CB, Bae SK

“…Mechanism-of-action-mediated DDIs are currently limited to those involving delayed gastric emptying, and most studies have found them to be clinically insignificant. …”
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Negligible benefit of oral single-dose sodium bicarbonate on continuous running performance: systematic review with meta-analysis of randomized, double-blind, placebo-controlled tr... by Larry E. Miller, Ruemon Bhattacharyya, Samuel J. Katz, Mehul Bhattacharyya, William G. Herbert

“…The certainty of evidence was assessed using the GRADE (Grading of Recommendations Assessment, Development and Evaluation) approach.Results Among 11 studies with 126 participants, all used a cross-over design. Most (84%) subjects were male, SB dose was typically 0.3 g/kg, and performance test durations ranged from 1 to 30 minutes (median: 4 minutes). …”
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The Role of Medical Societies and the Relevance of Clinical Perspective in the Evolving EU HTA Process: Insights Generated at the 2023 Fall Convention and Survey of the European Ac... by Elaine Julian, Oriol Solà-Morales, Maria João Garcia, Francine Brinkhuis, Mira Pavlovic, Carlos Martín-Saborido, Robin Doeswijk, Rosa Giuliani, Anne Willemsen, Wim Goettsch, Bernhard Wörmann, Urania Dafni, Heiner C. Bucher, Begoña Pérez-Valderrama, Renato Bernardini, Fabrizio Gianfrate, Carin A. Uyl-de Groot, Jörg Ruof

“…The WGs were attended by (i) 11, (ii) 10, (iii) 12, and (iv) 12 experts, respectively, representing a variety of national backgrounds and stakeholder profiles. The most relevant action points identified were as follows: (i) incorporation of clinical context into population, intervention, comparator, outcomes (PICO) schemes, (ii) timely provision of up-to-date therapeutic guidelines, (iii) ensuring the inclusion of MCBS insights into the EU HTA process, and (iv) considering randomized controlled trials (RCTs) as the gold standard and leveraging regulatory insights if development programs only include single-arm trials. …”
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