Characteristics of patients with idiopathic normal pressure hydrocephalus for whom neurosurgeons hesitate to perform shunt surgery: a nationwide hospital-based survey in Japan by Ryo Kawai, Hiroaki Kazui, Tetsuya Ueba, Natsuko Nakamura, Marina Minami, Madoka Nakajima, Shigeki Yamada, Haruhiko Kishima, Hideki Kanemoto, Chifumi Iseki, Etsuro Mori

“…Of them, 30 (4.6%) had a policy of not performing shunt surgery at their own facility and referred patients to other appropriate facilities, and 139 (21.2%) did not perform any shunt surgeries in 2022. The most common number of shunt surgeries performed in 2022 was 1–5 surgeries per facility, accounting for 257 facilities (57.1%). …”
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The Use of Heterologous Antigens for Biopanning Enables the Selection of Broadly Neutralizing Nanobodies Against SARS-CoV-2 by Vazirbek S. Aripov, Anna V. Zaykovskaya, Ludmila V. Mechetina, Alexander M. Najakshin, Alexander A. Bondar, Sergey G. Arkhipov, Egor A. Mustaev, Margarita G. Ilyina, Sophia S. Borisevich, Alexander A. Ilyichev, Valentina S. Nesmeyanova, Anastasia A. Isaeva, Ekaterina A. Volosnikova, Dmitry N. Shcherbakov, Natalia V. Volkova

“…As a result of these mutations, most monoclonal neutralizing antibodies have lost their efficacy, as they are unable to neutralize new variants. …”
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Methylation of a group of microRNA genes as a marker for the diagnosis and prognosis of non-small cell lung cancer by V. I. Loginov, M. S. Gubenko, A. M. Burdennyy, I. V. Pronina, P. V. Postnikov, Yu. A. Efimova, F. V. Radus, E. S. Mochalova, T. P. Kazubskaya

“…Lung cancer, representing a difficult-to-diagnose heterogeneous malignant neoplasm, is characterized by an asymptomatic course up to late stages, a high incidence of adverse outcomes, and a high probability of metastasis. Its most common form is non-small cell lung cancer (NSCLC). …”
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Effectiveness assessment and spatial distribution characteristics of helium source rocks in the Shixi Block along the eastern margin of the Ordos Basin by Yangmei CHANG, Chao LIU, Beilei SUN

“…Notably, both sandstones in the lower Shihezi Formation and most strata in the Shanxi Formation exhibit high helium generation volumes. …”
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Influence of phytochemicals on growth performance, gut morphology and ceca microbiome in broilers fed aflatoxin-contaminated diet and raised under high stocking density and heat st... by Kittisak Insawake, Thaweesak Songserm, Ornprapun Songserm, Chainarong Rattanakreetakul, Yongyuth Theapparat, Kazeem D. Adeyemi, Konkawat Rassmidatta, Yuwares Ruangpanit

“…The heat stress index exceeded 160 for most of the experimental period. Feed efficiency was significantly lower in the AFT group than in the CON, FVN, IQA, and combination groups, while the BCT group showed no significant difference from others. …”
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Modulatory effect of various essential oils on different GABAA receptor subtypes present in the central nervous system by Christian Böhm, Anna-Lena Wiessler, Dieter Janzen, Julian Nausester, Benedikt Slavik, Helene M. Loos, Carmen Villmann, Andrea Buettner

“…Although GABAAR modulation has been demonstrated, most studies do not discriminate between different GABAAR subtypes present in the central nervous system. …”
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Relationships among cortical activation, cognition, and blood biomarkers in two types of dementia determined using functional near-infrared spectroscopy by Nairong Ruan, Nairong Ruan, Ming Liang, Ming Liang, Yuehong Liu, Xi Mei, Chengying Zheng

“…ObjectiveThe most prevalent types of dementia in older adults are Alzheimer's disease (AD) and Lewy body dementia (LBD), and they have overlapping clinical symptoms. …”
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Multi-stage urethroplasy for anterior urethral strictures: objective parameters of long-term efficacy and patient-reported outcomes by V. P. Glukhov, A. V. Ilyash, K. S. Vasilev, N. V. Slyusarenko, R. S. Ismailov, V. V. Mitusov, D. V. Sizyakin, M. I. Kogan

“…Multi-stage urethral surgery is used in cases of the most complex urethral strictures. The evaluation of surgical treatment results given by patients is a significant criterion for the efficacy of urethroplasty along with the assessment of urethral patency through instrumental examinations.Objective. …”
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PD-1 inhibition for relapse after allogeneic transplantation in acute myeloid leukemia and myelodysplastic syndrome by John M. Magenau, David G. Frame, Mary Riwes, John Maciejewski, Sarah Anand, Attaphol Pawarode, Anamarija M. Perry, Marcus Geer, Thomas Braun, Monalisa Ghosh, Pavan Reddy

“…Immune toxicities were frequent, with 37.5% of patients developing severe (grade 3-4) GVHD after pembrolizumab, of which most had resistance to corticosteroids and contributed to death in 4 patients (25%). …”
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Real-world treatment patterns of patients with EGFR exon 20 insertion–mutated advanced NSCLC treated with amivantamab or mobocertinib after platinum-based chemotherapy: A multi-dat... by Alexander Spira, Dexter Waters, Tao Ran, Pratyusha Vadagam, Jinghua He, Julie Vanderpoel, Anjali Donnelly, Iris Lin

“…Patient characteristics were consistent with previous studies. Most patients received amivantamab or mobocertinib as second-line (57 % and 50 %) or third-line (32 % and 33 %) therapy. …”
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Physical activity levels in participants of UTAD physical exercise program: Accelerometry versus IPAQ by Guilherme Vilela, Isabel Machado, Alexandre Aleixo, Luís Vaz, Graça Pinto, Conceição Rainho, Nuno Leite

“…Analysis of the accelerometer data revealed that most participants engaged in sedentary activity (52.1%), followed by light (35.5%) and moderate or vigorous activity (12.4%) while the IPAQ revealed a large sample percentage perceived less sedentary activity (39.8%) and more moderate or vigorous activity (21.3%). …”
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PGL-EXPO feasibility study of exposure to SDHi fungicides and risk of hereditary SDHx paraganglioma or pheochromocytoma by Astrid Coste, Alexandre Buffet, Margaux Duboeuf, Sabrina Boudif, Lény Grassot, Boutheina Ouelaa, Annabelle Sueur, Timgad Lounis, Olivia Pérol, Béatrice Fervers, Anne-Paule Gimenez-Roqueplo

“…Missing data on domestic exposure to pesticides were more frequent for the households most back-in-time. Even for the oldest residential addresses, at least 81% of the addresses had a precise geocoding. …”
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The use of low doses of gabapentin in patients with neuropathic pain and with thrombocytopenia by O. K. Levchenko, E. G. Gemdzhian, G. M. Galstyan

“…Approximately 21–27% of patients with blood system diseases receive opioid analgesics, with neuropathic pain being one of the most common reasons for prescription. Gabapentin is used as a first-line drug for neuropathic pain (NP), but has been poorly studied in patients with blood system diseases.The objective was to study the effectiveness and safety of gabapentin in patients with blood system diseases with chronic pain.Materials and methods. …”
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Advancements in biomaterials and bioactive solutions for lumbar spine fusion cages: Current trends and future perspectives by Iulian Antoniac, Veronica Manescu (Paltanea), Gheorghe Paltanea, Aurora Antoniac, Marco Fosca, Dan Laptoiu, Julietta V. Rau

“…Additionally, some of the most met-in-clinical practice lumbar interbody cages with a detailed description of their geometry and examples of clinical trials performed worldwide are provided. …”
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Efficacy and safety of venetoclax in relapsed/refractory chronic lymphocytic leukemia in Russia routine clinical practice by E. A. Dmitrieva, S. V. Voloshin, K. D. Kaplanov, V. Touliet, V. V. Zasypkina, O. V. Magdych, E. F. Klinushkina

“…Chronic lymphocytic leukemia (CLL) is a slowly progressive malignant disease that results in uncontrolled proliferation and accumulation of B-lymphocytes in the blood and bone marrow, and is the most common form of leukemia in Western countries. …”
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Study of the Effect of Proton Pump Inhibitors on the Development of Hypomagnesemia in Patients with Paroxysmal Atrial Fibrillation on the Background of Autonomic Sinus Node Dysfunc... by Ya. G. Bozhko, M. V. Arkhipov, N. A. Belokonova

“…When choosing PPIs for arrhythmological patients with concomitant gastro-duodenal pathology, it is advisable to be guided by the complexing activity of drugs with respect to magnesium ions: the most pronounced metal-ligand interaction with magnesium was shown by rabeprazole and pantoprazole, and the least – omeprazole and esomeprazole.…”
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Risk factors, management, and outcomes of amniotic fluid embolism: A multicountry, population-based cohort and nested case-control study. by Kathryn E Fitzpatrick, Thomas van den Akker, Kitty W M Bloemenkamp, Catherine Deneux-Tharaux, Alexandra Kristufkova, Zhuoyang Li, Timme P Schaap, Elizabeth A Sullivan, Derek Tuffnell, Marian Knight

“…However, applying different case definitions did not materially alter findings regarding risk factors for AFE and factors associated with poor maternal outcomes amongst women with AFE. Using the most liberal case definition (UK) and adjusting for the severity of presentation when appropriate, women who died were more likely than those who survived to present with cardiac arrest (89% versus 40%, adjusted odds ratio [aOR] 10.58, 95% confidence interval [CI] 3.93-28.48, p < 0.001) and less likely to have a source of concentrated fibrinogen (40% versus 56%, aOR 0.44, 95% CI 0.21-0.92, p = 0.029) or platelets given (24% versus 49%, aOR 0.23, 95% CI 0.10-0.52, p < 0.001). …”
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Exploring the Correlation between GCSI Score and GES in Type 2 Diabetic Patients—Proposing a GCSI Cut-off Score for Guiding GES Utilization: A Record-centric Research Approach by Rifika Bansal, Ravi Kant, Vandana K Dhingra, Manisha Naithani, Mukesh Darshan, Mukesh Bairwa, Ashwin Parchani, Balachandra Routhu

“…The delayed group exhibited significantly higher GCSI scores (30.53 ± 7.51) with most individuals having GCSI scores above 18 with significant <i>p</i>-value (<i>p</i> < 0.001). …”
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Virulence profiling, biofilm formation, and antimicrobial resistance pattern of enterococci associated with poultry and livestock feeds by Samia Salam, Naeem Ahammed Ibrahim Fahim, Md. Nahid Ashraf, Rony Ibne Masud, Rownak Jahan, Md. Tabeer Hossain Antor, Md. Abdullah Evna Hasan, Zuhayr Bakhtiyar, Dilruba Akter Jany, Md. Liton Rana, Md. Shafiqul Islam, Md. Tanvir Rahman

“…In poultry feed, this was followed by resistance to Erythromycin, Rifampin, and Vancomycin, whereas in livestock feed, it was followed by Erythromycin, Tetracycline, and other antibiotics. Most isolates were positive for multiple virulent genes e.g., agg, pil, fsrB, and fsrC genes. …”
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Drawing as an experience. Knowledge, simulation and participation by Giuseppe Amoruso

“…(Hutchins, 1970)</p><p>Donald Schön’s work on organizational learning and reflective practice that tends to receive the most attention in the literature, his exploration of the nature of learning systems and the significance of learning in changing societies has helped to define debates around the so called ‘<em>learning society’</em>. …”
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