Association mapping and candidate gene identification for drought tolerance in sorghum by Huiting Min, Huiting Min, Kang Wang, Kang Wang, Tiantian Wang, Tiantian Wang, Xinxiu Cheng, Xinxiu Cheng, Ephrem Habyarimana, Yongfei Wang, Yongfei Wang, Die Hu, Die Hu, Yi-Hong Wang, Lihua Wang, Lihua Wang

“…IntroductionWater is essential for plant growth, and drought is one of the most predominant constraints on crop yield. Sorghum is a well-known drought-tolerant crop model, and sorghum landraces possess novel alleles for local adaptation.MethodsIn this study, we evaluated a sorghum mini core panel of 239 landraces sampled globally for shoot and root growth under simulated drought conditions using 10% and 20% polyethylene glycol (PEG) in 2020 and 2024, and measured drought tolerance using the seedling tolerance coefficient (STC).Results and discussionPhenotypic analysis showed that more accessions produced more roots than longer roots when exposed to 10% PEG; however, at 20% PEG, more accessions produced longer roots than more roots, reflecting the adaptability of some accessions to drought stress. …”
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Quantification of fibroblast growth factor 23 and N-terminal pro-B-type natriuretic peptide to identify patients with atrial fibrillation using a high-throughput platform: A valida... by Winnie Chua, Jonathan P Law, Victor R Cardoso, Yanish Purmah, Georgiana Neculau, Muhammad Jawad-Ul-Qamar, Kalisha Russell, Ashley Turner, Samantha P Tull, Frantisek Nehaj, Paul Brady, Peter Kastner, André Ziegler, Georgios V Gkoutos, Davor Pavlovic, Charles J Ferro, Paulus Kirchhof, Larissa Fabritz

“…Using an experimental semi-quantitative biomarker assay, B-type natriuretic peptide (BNP) and fibroblast growth factor 23 (FGF23) were recently identified as the most suitable biomarkers for detecting AF in combination with simple morphometric parameters (age, sex, and body mass index [BMI]). …”
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The Role of Robot-Assisted Technique in Treating Adult Degenerative Scoliosis with Circumferential Minimal Invasive Correction Surgery – A Retrospective Analysis of 51 Co... by Zhang Q, Chen Z, Lin Y, Zhang X, Wu W, Liang Y

“…Qiang Zhang,* Zhe Chen,* Yazhou Lin, Xingkai Zhang, Wenjian Wu,* Yu Liang* Department of Orthopedics, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200025, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yu Liang, Department of Orthopedics, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, People’s Republic of China, Email hugoliang@126.com Wenjian Wu, Department of Orthopedics, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, People’s Republic of China, Email drwuwenjian@126.comStudy Design: Retrospective chart review.Objective: This study aims to investigate the application of robots in treating adult degenerative scoliosis (ADS) with circumferential minimal invasive surgery (cMIS).Background: The cMIS is useful but faces a lot of challenges in correcting ADS. One of the most important challenges is the difficulty in screw placement. …”
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A Highly Divergent Mitochondrial Genome in Extant Cape Buffalo From Addo Elephant National Park, South Africa by Deon deJager, Marlo Möller, Eileen Hoal, Paul vanHelden, Brigitte Glanzmann, Cindy Harper, Paulette Bloomer

“…We discuss several potential sources of this mitogenome but propose that it most likely originated through introgressive hybridisation with an extinct buffalo species, either S. acoelotus or S. antiquus. …”
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How can we support the individual breastfeeding experience? Quantitative results from a mixed-methods study by Theresa Philomena Ertlmaier, Oana Costea, Anja Borgmann-Staudt, Monika Berns, Georg Weikert, Mathilde Kersting, Magdalena Balcerek

“…Data were analysed descriptively and through multivariate analysis. Results Most of the 326 participating mothers had initiated breastfeeding in the delivery room (94.7%). …”
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TREN PENELITIAN PEMBELAJARAN BIOLOGI BERBASIS CITIZEN SCIENCE UNTUK MELATIHKAN KETERAMPILAN ABAD 21 by Utari Akhir Gusti, Topik Hidayat, Nur Hamidah, Siti Sriyati

“…The 21st century skills with which CS is most frequently reported are collaboration and communication. …”
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Interrelations of physical state parameters and biological age of students in the process of physical education by Oleksandr Pryimakov, Marek Sawczuk, Stanislav Prysiazhniuk, Nataliya Mazurok, Oleksandr Petrachkov

“…It was found that the key indicators of students' physical state (PS) structure, which exerted the most significant influence on BMI, differ between young men and women. …”
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Prognostic significance of the number of hepatic lesions in multifocal intrahepatic cholangiocarcinoma after radical resection: an IPTW propensity-score analysis by Xin Zhang, Xi-Tai Huang, Jin-Zhao Xie, Ai-Qing Fu, Wei Chen, Jian-Peng Cai, Li-Jian Liang, Xiao-Yu Yin

“…This study aimed to compare the survival of intrahepatic cholangiocarcinoma (iCCA) with different numbers of hepatic lesions and select patients benefiting most from surgery in multifocal iCCA. Methods A cohort of 354 consecutive iCCA patients were included. …”
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Prevalence and predictors of malocclusion among students in special needs schools in Amhara region, Ethiopia by Amare Teshome Tefera, Biruk Girma Bekele, Zelalem Aniley, Aynishet Adane, Tadesse Awoke Ayele, Kefyalew Ayalew Getahun, Simegnew Handebo, Semira Ali, Abebe Muche

“…Abstract Background Malocclusion is one of the most common oral health conditions globally, following dental caries and periodontal disease. …”
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Psychological adaptation and quality of life of patients who underwent lower limb amputation due to cancer by O Yu Shchelkova, M V Iakovleva, E B Usmanova, E A Sushentsov, D I Sofronov

“…It was found that functional capability (p<0.01), objective (p<0.001) and subjective (p<0.001) severity of pain syndrome, as well as employment (p=0.05) have the lowest indicators in group 1 compared with group 2; at the same time, the levels of QoL in both groups of patients do not differ and do not correspond the expert assessment, exceeding it; patients rate their cognitive and emotional activity most highly; the lowest, physical and role activity, and financial impact. …”
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The rose of the Sainte-Chapelle in Paris: sophisticated stained glasses for late medieval painters by Hunault, Myrtille Odile Jacqueline Yvonne, Bauchau, Fanny, Boulanger, Karine, Hérold, Michel, Calas, Georges, Lemasson, Quentin, Pacheco, Claire, Loisel, Claudine

“…In light of the variability criteria, the multivariate analysis of the chemical composition allowed inferring that most glasses originate from the same production glasshouse. …”
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TDP-43 pathology is associated with divergent protein profiles in ALS brain and spinal cord by Emily Feneberg, Alexander G. Thompson, Philip D. Charles, Iolanda Vendrell, Benedikt M. Kessler, Roman Fischer, Olaf Ansorge, Elizabeth Gray, Kevin Talbot, Martin R. Turner

“…Increased abundance of TDP-43 in the detergent-insoluble fraction of ALS cortex and spinal cord tissue confirmed disease-specific protein enrichment by serial fractionation. The most striking alterations between ALS and other conditions were found in the detergent-insoluble fraction of spinal cord, with predominant enrichment of endosomal and extracellular vesicle pathways. …”
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Microbial and Biochemical Analyses of High-Quality, Long-Ripened, Blue-Veined Cabrales Cheese by Javier Rodríguez, Paula Rosa Suárez, Souvik Das, Lucía Vázquez, Sonam Lama, Ana Belén Flórez, Jyoti Prakash Tamang, Baltasar Mayo

“…Glutamic acid (≈20 mg g⁻¹) was the most abundant free amino acid in all samples, followed by lysine, leucine, and valine (≈10–13 mg g⁻¹). …”
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Generation of Codon-Optimized Fad3 Gene Transgenic Bovine That Produce More n-3 Polyunsaturated Fatty Acids by Guanghua Su, Zhuying Wei, Chunling Bai, Danyi Li, Xiaoyu Zhao, Xuefei Liu, Lishuang Song, Li Zhang, Guangpeng Li, Lei Yang

“…Polyunsaturated fatty acids (PUFAs) such as linoleic acid (18:2, n-6) and α-linolenic acid (18:3, n-3) are essential for the growth, development, and well-being of mammals. However, most mammals, including humans, cannot synthesize n-3 and n-6 PUFAs and these must be obtained through diet. …”
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Harnessing AlphaFold to reveal hERG channel conformational state secrets by Khoa Ngo, Pei-Chi Yang, Vladimir Yarov-Yarovoy, Colleen E Clancy, Igor Vorobyov

“…To design safe, selective, and effective new therapies, there must be a deep understanding of the structure and function of the drug target. One of the most difficult problems to solve has been the resolution of discrete conformational states of transmembrane ion channel proteins. …”
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Inclusion of Solar Elevation Angle in Land Surface Albedo Parameterization Over Bare Soil Surface by Zhiyuan Zheng, Zhigang Wei, Zhiping Wen, Wenjie Dong, Zhenchao Li, Xiaohang Wen, Xian Zhu, Dong Ji, Chen Chen, Dongdong Yan

“…Solar elevation angle is one of the most important factors for parameterizing bare soil surface albedo and must be considered in the parameterization scheme, especially in arid and semiarid areas with low soil moisture content. …”
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Effects of plant-origin binder sources in Asian catfish diets on growth, feed quality, blood chemistry, liver and gut health, and economic efficiency by Muhammad Anamul Kabir, Sanzida Haque, Shishir Kumar Nandi, Tanwi Dey, Md. Sakhawat Hossain, El-Sayed Hemdan Eissa, Martina Irwan Khoo, Zulhisyam Abdul Kari, Nor Dini Rusli, Hien Van Doan

“…Growth performance metrics, including final weight, weight gain, total biomass, specific growth rate, feed conversion ratio, and protein efficiency ratio, varied significantly (p < 0.05) among dietary treatments, with the D2 group demonstrating the most favorable outcomes. Additionally, fish from the D2 group exhibited significantly higher (p < 0.05) crude protein levels lower crude lipid content in whole-body composition. …”
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The Impact of Yes-Associated Protein 1 (YAP1) Expression Patterns in Locally Advanced Breast Cancer: Associations with Pathological Response and Tumor Features by Osman Erinc, Sabin Goktas Aydin, Taskin Erkinuresin, Ozgur Yilmaz, Ahmet Aydin, Sevinc Dagistanli, Murat Akarsu

“…<i>Results</i>: YAP1 expression had a significant relationship with tumor subtype (<i>p</i> = 0.001), being most frequent in HER-2-positive tumors (55.6%) and least frequent in luminal tumors (11.1%). …”
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Relationship between epithelial cell adhesion molecule (EpCAM) overexpression and gastric cancer patients: A systematic review and meta-analysis. by Meng Dai, Fei Yuan, Cuiqun Fu, Guodong Shen, Shilian Hu, Gan Shen

“…<h4>Objectives</h4>The epithelial cell adhesion molecule (EpCAM) is one of the most commonly used markers of cancer stem cells (CSCs), but the clinical and prognostic significance of EpCAM in gastric cancer (GC) remains disputable. …”
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Elevated pulmonary tuberculosis biomarker miR-423-5p plays critical role in the occurrence of active TB by inhibiting autophagosome-lysosome fusion by Huihui Tu, Su Yang, Tingting Jiang, Liliang Wei, Liying Shi, Changming Liu, Chong Wang, Huai Huang, Yuting Hu, Zhongliang Chen, Jing Chen, Zhongjie Li, Jicheng Li

“…Bioinformatics analysis unveiled miR-423-5p as the most likely candidate in regulating autophagosome maturation. …”
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