Predictors of Immune Fitness and the Alcohol Hangover: Survey Data from UK and Irish Adults by Joris C. Verster, Agnese Merlo, Maureen N. Zijlstra, Benthe R. C. van der Weij, Anne S. Boogaard, Sanne E. Schulz, Jessica Balikji, Andy J. Kim, Sherry H. Stewart, Simon B. Sherry, Johan Garssen, Gillian Bruce, Lydia E. Devenney

“…The alcohol hangover is the most frequently reported negative consequence of alcohol consumption and is defined as the combination of negative mental and physical symptoms, which can be experienced after a single episode of alcohol consumption, starting when blood alcohol concentration (BAC) approaches zero. …”
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Analysis of standard vs dose-escalated stereotactic body radiation therapy in localized prostate cancer: a comparative evaluation of survival outcomes by Bichun Xu, Bichun Xu, Xianzhi Zhao, Xianzhi Zhao, Tingting Wei, Yiyin Liang, Weiwei Zhang, Liang Chen, Zuping Lian, Huojun Zhang

“…Patients with pre-existing health conditions were less likely to develop distant metastasis (p=0.047). Most patients tolerated SBRT with minimal toxicity, and no grade 3 or higher adverse events were observed.ConclusionEscalating the biologically effective dose above standard levels did not yield a significant improvement in tumor control or survival outcomes compared to conventional SBRT dosing for localized PCa. …”
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Exosomes derived from hypoxia-preconditioned M2 macrophages alleviate degeneration in knee osteoarthritis through the miR‑124‑3p/STAT3 axis by Hao Li, Yuze Yang, Yuanpeng Gao, Bo Li, Jiaju Yang, Pengyu Liu, Min Zhang, Guangzhi Ning

“…Results Compared to Nor-Exos, Hypo-Exos exhibited more effective therapeutic effects in both inflammatory chondrocytes and OA rats. miR-124-3p was identified as the most upregulated miRNA in Hypo-Exos, and the suppression of miR-124-3p expression significantly inhibited the biological effects of Hypo-Exos. …”
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Minimally Invasive Lumbar Decompression (MILD) in Patients with Lumbar Spinal Stenosis: A Systematic Review of Randomized and Prospective Trials by Orhurhu V, Brancolini S, Zheng D, Snyder S, Jevotovsky DS, Chopra H, Sahni S, Li N, D’Souza RS, Evankovich M, Lynch B, Farrell ME, Alter BJ, Emerick T

“…Vwaire Orhurhu,1 Scott Brancolini,1 Danielle Zheng,1 Sean Snyder,1 David S Jevotovsky,2 Harman Chopra,3 Sidharth Sahni,2 Nathan Li,4 Ryan S D’Souza,5 Maria Evankovich,1 Brendan Lynch,1 Michael Edward Farrell,1 Benedict J Alter,1 Trent Emerick1 1Department of Anesthesiology & Perioperative Medicine, Division of Chronic Pain Management, University of Pittsburgh Medical Center, Pittsburgh, PA, USA; 2Department of Rehabilitation Medicine, NYU Langone Health, New York, NY, USA; 3Department of Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, MD, USA; 4Department of Orthopedic Surgery, Boston University School of Medicine, Boston, MA, USA; 5Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN, USACorrespondence: Sidharth Sahni, Email sisahni@gmail.comBackground/Importance: Lumbar spinal stenosis (LSS) remains one of the most common causes of pain and functional disability in patients with chronic pain. …”
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A Prospective Study on Yoga for Anterior Knee Pain in Adolescents by Stephanie Price, MD, Robert Martin, MD, Chand Shah, MPAS/PA-C/RYT 200, Matthew Ellington, MD

“…Background: Anterior knee pain (AKP) is one of the most common musculoskeletal complaints in adolescents. …”
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Comprehensive analysis of amino acid profile in camel milk: Implications for nutrition and sustainable development by Kuanysh Syman, Raushangul Uazhanova, Zhulduz Suleimenova, Rakhmatova Markhabo Rasulovna, , Elnura Xamdamova, Kuryozov Urinboy Sabirovich, N. Esanmurodova, Rustem Shichiyakh, Sabirova Nadira Kamiljanovna, Nasirova Saodat Abdullayevna, Sullieva Suluv Khurramovna, Khushbok Bobonazarovich Narbutaev, Bakhtiyor Menglikulov

“…Subtle geographical variations in amino acid profiles were observed, with samples from the Arabian Peninsula showing slightly higher concentrations of most essential amino acids. The unique amino acid profile and high protein digestibility of camel milk suggest its potential as a valuable nutritional resource, particularly in arid regions facing environmental and nutritional challenges. …”
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Chemotherapeutic drug scavenger-based combination therapy toward treating triple-negative breast cancer by Qingqing Yin, Yutong Zhong, Mengchun Chen, Weian Mao, Yuan Yang, Li Li, Dongyan Tian, Shuangshuang Liu, Ying Chen, Jiale Quan, Shiyu Li, Deli Zhuge, Xufei Zhang, Ledan Wang, Fang Wang, Yiming Chen, Xiaosheng Lu, Xiaoji Lin, Yijie Chen, Linzhi Yan

“…Abstract Triple-negative breast cancer (TNBC) is resistant to most antitumor treatments, leaving chemotherapy as the primary option. …”
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Enhancement of oxaliplatin efficacy and amelioration of intestinal epithelial damage by Lactobacillus rhamnosus GG through modulation of gut microbiota by Zijie Zhang, Zijie Zhang, Rui Li, Yilin Ren, Yilin Ren, Yalan Ni, Yalan Ni, Xiaoyu Shen, Xiaoyu Shen, Deli Yi, Deli Yi, Zheng-hong Xu, Yan Geng, Yan Geng, Qingjun You, Qingjun You

“…Despite advancements in targeted therapies and immunotherapies, traditional chemotherapy remains the primary treatment modality for most patients. Here, we explored the synergy between Lactobacillus rhamnosus GG (LGG), a probiotic, and the chemotherapeutic drug oxaliplatin (Oxp) in enhancing NSCLC treatment outcomes.MethodsWe utilized a BALB/c nude mouse subcutaneous tumor model to assess the therapeutic impacts of LGG and Oxp. …”
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Study of mutagenic effects with predicted carcinogenicity of 4-((5-decylthio)-4-methyl-4-H-1,2,4-triazole-3-yl)methyl)morpholine for further research in order to create a new drug... by I. V. Bushuieva, K. V. Petrova, B. P. Kyrychko, V. V. Parchenko

“…The value of such drugs is determined by the rapid and prolonged biological action, which is not accompanied by abrupt changes in homeostasis and pronounced side effects, which are characteristic of most pharmacological drugs of synthetic origin. In the context of a limited range of domestic antimicrobial and antifungal veterinary drugs on the national pharmaceutical market, one of the directions for solving this problem is the search, study, research, and development of drugs with antimicrobial and antifungal activity. …”
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Analysis of selenocysteine insertion sequence element, structures and functions and expression profiles of selenoprotein T in chicken by Ge Yansong, Cao Changyu, Wang Lili, Li Nan, Jiang Xiuqing, Li Jinlong

“…Up to now, 25 selenoprotein-encoding genes were identified in birds, however, only about half have been functionally characterized, most of which were involved in redox reactions. SelT was a Se-containing protein whose cellular function has not been characterized. …”
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Cerebral Amyloid Angiopathy-Related Inflammation: Clinical Characteristics and Treatment Experience by Wang X, Li J, Fu Q, Zheng H, Duan S, Gao Y, Luo H, Xu Y

“…Cognitive impairment (61.5%, n=8) emerged as the most frequent clinical manifestation, followed by headache (46.2%, n=6), epileptic seizures (30.8%, n=4), and focal neurological deficits (23.1%, n=3). …”
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Results of a clinical trial of the efficacy and safety of vildagliptin and metformin fixed combination in real clinical practice in Russia (MASTER study) by N. A. Demidov, M. B. Antsiferov, A. V. Zilov

“…For the other combination therapy group, metformin and sulfonylurea derivatives were most often selected (66.5%). In the Galvus Met® group, 68.7% of patients achieved an HbA1c level of <7.0% without proven hypoglycemia, which is significantly better compared to the group of other combinations (40.7%, p <0.001). …”
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Estimates, temporal evolution, and drivers of the global burden of cardiovascular disease attributable to particulate matter air pollution, 1990–2021: A systematic analysis from th... by Shuailing Liu, Huajie Yang, Mingzheng Li, Yinchu Guo, Zhaoqi Zhang, Wei Liu, Shuo Wu, Tong Liu, Shenghang Li, Juexin Zhang, Yuejia Wang, Luoxin Li, Peng Shi

“…Cardiovascular diseases (CVDs) are the most common non-communicable diseases worldwide. …”
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Genotypic ranking and repeatability coefficient in elephant grass genotypes for biomass production for energy applications by Maxwel Rodrigues Nascimento, Rogério Figueiredo Daher, Ana Kesia Faria Vidal, Josefa Grasiela Silva Santana, Moisés Ambrósio, Rafael Souza Freitas, Cleudiane Lopes Leite, Alexandre Gomes deSouza, Josilene Vargas Xavier, Paulo Ricardo dos Santos, Kleyton Danilo da Silva Costa, Antônio Félix da Costa, José Wilson da Silva

“…The genotypes King Grass, Taiwan A‐46, Pasto Panamá, Três Rios, and Guaçu/I.Z.2 were the most productive, adaptable, and stable, displaying potential for cultivation in the northern region of Rio de Janeiro and for use in breeding programs.…”
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Aplikasi Berbasis Progressive Web App (Mentoree) sebagai Layanan Pendampingan Pembelajaran Pemrograman di Universitas Brawijaya by Muhamad Fauzan Wahyudi, Lutfi Fanani, Adam Hendra Brata

“…Nadiem Makarim, the Minister of Education, Culture, Research, and Technology, responded by integrating technology into the national education curriculum. Most university departments in Indonesia now offer courses that incorporate information technology. …”
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Early neurological deterioration in patients with minor stroke: A single-center study conducted in Vietnam. by Dung Tien Nguyen, Ton Duy Mai, Phuong Viet Dao, Hung Tran Ha, Marco Fabus, Melanie Fleming, Minh Cong Tran

“…In the END group, we found that most patients had complications within the first 24 hours of stroke, accounting for 43.2%; the 24 - 48-hour window accounted for 35.2%, and the 48 - 72-hour window accounted for 21.6%. …”
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Integrated Analysis of Olive Mill Wastewaters: Physicochemical Profiling, Antifungal Activity, and Biocontrol Potential Against <i>Botryosphaeriaceae</i> by Elena Petrović, Karolina Vrandečić, Alen Albreht, Igor Gruntar, Nikola Major, Jasenka Ćosić, Zoran Užila, Smiljana Goreta Ban, Sara Godena

“…Among the OMWW treatments, Leccino and Buža showed the most significant antifungal activity against species from the <i>Botryosphaeriaceae</i> family. …”
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Segmental redistribution of myocardial blood flow after coronary sinus reducer implantation demonstrated by quantitative perfusion cardiovascular magnetic resonance by Kevin Cheng, Francisco Alpendurada, Chiara Bucciarelli-Ducci, Jose Almeida, Peter Kellman, Jonathan M. Hill, Dudley J. Pennell, Ranil de Silva

“…Conclusion: In patients with refractory angina undergoing CSR implantation, quantitative stress perfusion CMR demonstrated redistribution of myocardial perfusion across segments, from less ischemic to more ischemic myocardium, and across myocardial layers with greatest improvements in endocardial perfusion observed in the most ischemic myocardium. Further studies are needed to validate the different patterns of MBF redistribution that may occur after CSR implantation and correlate with clinical outcomes.…”
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Novel sequential modeling framework improves phytoplankton biomass predictions in response to multiple environmental stressors by Zhuyin Tong, Jiayu Guo, Yikai Liu, Lizhen Lin, Jixin Chen, Xin Liu, Bangqin Huang, Edward A. Laws, Wupeng Xiao

“…The combined effects of these stressors will result in an 18.3% reduction, with the most significant declines occurring in high‐chlorophyll areas during algal blooms. …”
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High-throughput photosynthetic phenotyping using hyperspectral reflectance in paddy rice (Oryza sativa L.) under field conditions by Xinfeng Yao, Tingting Qian, Huifeng Sun, Sheng Zhou, Wei Wang, Linyi Li

“…The combination of Savitzky-Golay (SG) preprocessing and stratified random sampling (data splitting Approach 1) consistently yielded the most accurate and stable model performance, except for Isat, where the Variable Sorting Normalization (VSN) and Approach 1 combination yielded better results. …”
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