Medication prescribing and pregnancy-related risk factors for women with type 2 diabetes of reproductive age within primary care: a cross-sectional investigation for the PREPARED s... by Kirsty Winkley, Helen Rogers, Anita Banerjee, Helen Murphy, Kia-Chong Chua, Anna Hodgkinson, Judith Parsons, Angus Forbes, Rita Forde, Alexandra M Famiglietti, Olubunmi Abiola, Anna Brackenridge, Mark Chamley, Lily Hopkins, Katharine F Hunt, Gavin Steele

“…Prescribed medications suggested the presence of numerous comorbidities, with diabetes medications (65%, n=471) and statins (20%, n=145) most frequently prescribed. 37% (n=268) of women took ≥3 medications, and a third (n=269) took medications not recommended for pregnancy. …”
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A single-centre retrospective study on the clinical characteristics of patients with hereditary angioedema and the therapeutic effect of lanadelumab by Yanhua Xu, Yinshi Guo

“…Ten patients (45.5%) experienced onset following minor trauma/local bumps/pressure/heat exposure, which was the most common precipitating factor; 7 patients (31.8%) experienced spontaneous onset without apparent precipitating factors. …”
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Neuroprotective effects of empagliflozin against scopolamine-induced memory impairment and oxidative stress in rats by Mahdieh Anoush, Neda Taghaddosi, Zahra Bokaei Hosseini, Fatemeh Rahmati, Soroush Bijani, Ali Kalantari-Hesari, Mir-Jamal Hosseini

“…Alzheimer’s disease (AD) is one of the most common age-related neurodegenerative disorders. …”
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Hermetia illucens meal from different substrates for replacing fishmeal: study on zebrafish as fish model by Chiara Sangiacomo, Laura Trombetta, Francesca Susini, Letizia Brogi, Rosario Licitra, Maria Machese, Patrizia Falabella, Antonio Franco, Carmen Scieuzo, Gianmarco Del Vecchio, Tiziano Verri, Baldassare Fronte

“…The meal produced from the larvae is also one of the most promising candidate protein sources for replacing fishmeal in aquafeeds. …”
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Prognostic Value of Biomarkers in Cancer Patients Treated With Immune Checkpoint Inhibitor Therapy by Christopher Mann, MD, Ulrike Pailer, MSc, Andreas Spannbauer, MD, Fardin Hamidi, MD, Aliza Veronika Braser, Martin Hülsmann, MD, Christian Gerges, MD, PhD, Michael Gottsauner-Wolf, MD, Mariann Gyöngyösi, MD, Markus Raderer, MD, Martin Riesenhuber, MD, PhD, Christian Hengstenberg, MD, Jutta Bergler-Klein, MD, Thomas A. Zelniker, MD, MSc

“…Over a median follow-up of 67 weeks, 190 patients (35%) died, and 103 cardiovascular hospitalizations (most commonly due to stroke, coronary artery disease, and heart failure) occurred in 76 patients (14%), resulting in a primary composite endpoint rate of 46.7 events per 100 patient-years. …”
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GAME AS AN ELEMENT OF HYGIENE MOTIVATION OF PRE-SCHOOLERS by V.S. Melnyk, L.F. Horzov

“…Analyzing the initial level of children`s knowledge it has been found that most children know about the need to brush their teeth, but not everyone understands the importance of brushing teeth after eating. …”
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Safeguarding athletes and anti-doping: applying theories of vulnerability by Angela J. Schneider, Angela J. Schneider, Nelson Morales Páez, Nelson Morales Páez, Yaneí Lezama Ramírez, Yaneí Lezama Ramírez, Loughran Butcher

“…In this article, utilizing the method of critical philosophical and ethical analysis, we attempt to provide evidence regarding why the intersection between safeguarding and anti-doping is very important and requires critical analysis; moreover, we suggest that feminist bioethics reflections on vulnerability can offer unique insights into key issues related to safeguarding in sport, such as the autonomy of athletes and the concept of ‘protected persons' and, most pertinent to this research, to the concepts of athlete vulnerability and anti-doping in sport. …”
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The linguocultural concept of 疫/pandemic/пaндeмия in Chinese, English, and Russian linguistic consciousness by Yanlei Ge

“…In the field of humanities, most pandemic-related studies use introspective methods such as description and interpretation, indicating to some extent subjective and one-sided conclusions. …”
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Epidemiological investigation of venomous snakebites in Yunnan Province by Qinfen Gao, Yajun Teng, Chao Xiao, Rui Zeng, Bin Han, Hong Gao, Jianhai Wang, Xiaoyan Li, Canju Yang, Jianneng Dai, Chunxi Li, Qunyan Huang, Zengzheng Li, Wei Zhang

“…These findings align with the annual distribution of anti-venom serum administered to affected individuals. Most incidents occurred during June to September, primarily in mountainous and forested areas or paddy fields, comprising approximately 52.40% of the total cases. …”
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Ischemia during exercise stress testing, an indication of coronary vasomotor dysfunction? by Diantha J.M. Schipaanboord, Tijn P.J. Jansen, Luuk Scherpenhuijzen, Caïa Crooijmans, Aukelien C. Dimitriu-Leen, Pim van der Harst, Tim P. van de Hoef, René van Es, Hester M. den Ruijter, Peter Damman, N. Charlotte Onland-Moret, Suzette E. Elias-Smale

“…For each patient we requested the most recent EST report. ESTs were denoted as positive for ischemia if clinically significant ST-segment depression was detected. …”
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Fatty acid composition and biological activity of four olive oils from Kabylia (Algeria) against Rhyzopertha dominica (Coleoptera: Bostrychidae) infesting wheat seeds by Safia KERBEL, Ines ABDELLI, Hakim AZZI, Jean-Francois DEBRAS, Abdellah KELLOUCHE

“…The use of conventional insecticides is one of the most widely used methods of controlling pests of stored grains. …”
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Green-synthesized zinc oxide nanoparticles from Garcinia mangostana leaf extract: A promising antibacterial agent for poultry by R. K. Rusli, Zurmiati Zurmiati, R. Mutia, S. Reski, A. Darmawan, C. Hidayat, M. E. Mahata, M. Hilmi, A. Yuniza

“…Results: The positive control demonstrated the most significant inhibition zones across all bacterial strains. …”
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Fatty acid biomarkers of dairy fat consumption and incidence of type 2 diabetes: A pooled analysis of prospective cohort studies. by Fumiaki Imamura, Amanda Fretts, Matti Marklund, Andres V Ardisson Korat, Wei-Sin Yang, Maria Lankinen, Waqas Qureshi, Catherine Helmer, Tzu-An Chen, Kerry Wong, Julie K Bassett, Rachel Murphy, Nathan Tintle, Chaoyu Ian Yu, Ingeborg A Brouwer, Kuo-Liong Chien, Alexis C Frazier-Wood, Liana C Del Gobbo, Luc Djoussé, Johanna M Geleijnse, Graham G Giles, Janette de Goede, Vilmundur Gudnason, William S Harris, Allison Hodge, Frank Hu, InterAct Consortium, Albert Koulman, Markku Laakso, Lars Lind, Hung-Ju Lin, Barbara McKnight, Kalina Rajaobelina, Ulf Risérus, Jennifer G Robinson, Cécilia Samieri, David S Siscovick, Sabita S Soedamah-Muthu, Nona Sotoodehnia, Qi Sun, Michael Y Tsai, Matti Uusitupa, Lynne E Wagenknecht, Nick J Wareham, Jason Hy Wu, Renata Micha, Nita G Forouhi, Rozenn N Lemaitre, Dariush Mozaffarian, Fatty Acids and Outcomes Research Consortium (FORCE)

“…After adjustment for potential confounders, including measures of adiposity (BMI, waist circumference) and lipogenesis (levels of palmitate, triglycerides), higher levels of 15:0, 17:0, and t16:1n-7 were associated with lower incidence of T2D. In the most adjusted model, the hazard ratio (95% CI) for incident T2D per cohort-specific 10th to 90th percentile range of 15:0 was 0.80 (0.73-0.87); of 17:0, 0.65 (0.59-0.72); of t16:1n7, 0.82 (0.70-0.96); and of their sum, 0.71 (0.63-0.79). …”
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Chloride as a Partial Nitrate Substitute in Hydroponics: Effects on Purslane Yield and Quality by George P. Spyrou, Ioannis Karavidas, Theodora Ntanasi, Sofia Marka, Evangelos Giannothanasis, Gholamreza Gohari, Enrica Allevato, Leo Sabatino, Dimitrios Savvas, Georgia Ntatsi

“…Partial replacement of N with Cl (N30) emerged as the most promising strategy, benefiting quality traits and effectively reducing nitrate content without significantly compromising yield.…”
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Association between carotid plaque calcification and clinical outcomes of symptomatic cerebral small vessel disease by Jing Zhang, Jing Zhang, Shuo Zhao, Shuo Zhao, Shuo Zhao, Xunyao Hou, Xunyao Hou, Xinyao Wang, Xinyao Wang, Yunliang Guo, Yunliang Guo, Ximing Wang

“…ObjectiveAtherosclerosis is the most common pathological change of cerebral small vessel disease (CSVD). …”
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Global burden trends and forecasts for MAFLD in adolescents and young adults from 1990 to 2021 by Shiying Ruan, Liyuan Huang, Jie Song, Zusong Yi, Weipeng Sun, Fankun Zhou, Chang Feng, Guihua Du, Jie Xie, Yuanan Lu, Guangqin Fan

“…Advanced statistical methods, including the estimated annual percentage change (EAPC) and Bayesian age-period-cohort (BAPC) modeling, were used to deliver the most current and thorough epidemiological assessment of MAFLD in this demographic. …”
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IMPACT OF POLYMORPHISM OF CARDIOVASCULAR RISK GENES ON ARTERIAL REMODELLING DEVELOPMENT DEPENDING ON PRESENCE OF SYSTEMIC HYPERTENSION by A. I. Chernyavina, M. V. Surovtseva

“…Among the patients with borderline arteries lesion with AH or with none, the most significant are genotypes С/Т and ТТ of polymorphism Thr174Met rs4762 gene AGT, genotypes С/Т and Т/Т of polymorphism C825T rs5443 gene GNB3, genotypes С/Т and Т/Т of polymorphism C677T rs1801133 gene MTHFR, and genotypes С/С of polymorphism G/C rs4253778 gene PPARα. …”
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Identifying small thymomas from other asymptomatic anterior mediastinal nodules based on CT images using logistic regression by Wenfeng Feng, Runlong Lin, Wenzhe Zhao, Haifeng Cai, Jingwu Li, Yongliang Liu, Lixiu Cao, Lixiu Cao

“…DCA confirmed the model’s enhanced clinical utility across most threshold probabilities. In the prospective test set, the LR showed an AUC of 0.908 (95% CI: 0.765-1.00), comparable to the senior radiologist’s performance (AUC = 0.912 [95% CI: 0.765-1.00], P = 0.961), higher than the intermediate radiologist’s performance (AUC = 0.762 [95% CI: 0.554-0.969], P = 0.094), and significantly better than the junior radiologist’s performance (AUC = 0.700 [95% CI: 0.463-0.937], P = 0.044).ConclusionsThe CT-based LR model demonstrated well diagnostic performance comparable to that of senior radiologists in differentiating small thymomas from other asymptomatic SAMNs. …”
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Mortality trends related to cardiogenic shock in heart failure patients aged 25 and older across the United States: A study utilizing the CDC WONDER database from 1999 to 2023 by Abdullah Naveed Muhammad, Sivaram Neppala, Himaja Dutt Chigurupati, Muhammad Omer Rehan, Hamza Naveed, Rabia Iqbal, Bazil Azeem, Ahila Ali, Mushood Ahmed, Prakash Upreti, Mobeen Zaka Haider, Yasar Sattar, Jamal S. Rana, Gregg C. Fonarow

“…Results: Between 1999 and 2023, there were 108,514 deaths linked to cardiogenic shock among heart failure patients, with AAMRs increasing from 1.2 to 4.6 per 100,000 (AAPC: 5.90). The most significant increases occurred from 2009 to 2021 (APC: 14.17), followed by a sustained rise from 2021 to 2023 (APC: 7.83). …”
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Genetic Testing of a High-End ‘Angel Skin’ Precious Coral Necklace Identifies a Species New to the Precious Coral Trade and Potentially New to Science by Bertalan Lendvay, Laurent E. Cartier, Akitsugu Sato, Michael S. Krzemnicki, Masanori Nonaka, Nina Yasuda, Kenji Takata, Takeshi Hayashibara, Nadja V. Morf, Nozomu Iwasaki

“…One highly appreciated shade is the light pink color, the so-called ‘angel skin’. This color is most often associated with <i>Pleurocorallium elatius</i> and <i>Pleurocorallium secundum</i>, species listed in CITES Appendix III. …”
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