Characteristics of B-lymphocyte subpopulations in renal transplant recipients by S. V. Zybleva, S. L. Zyblev

“…The presence of multiple subsets of B-cells with specific regulatory functions capable of modulating inflammatory responses havebeen detected. Most of the studies of Bregs function were carried out in the context of autoimmune and infectious diseases, whereas the objective of this research was to study the characteristics of the main, activated and tolerogenic subpopulations of B lymphocytes in patients who underwent kidney transplantation. …”
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Impact of second victim experience and support and psychological empowerment on depressive symptoms among nurses in China -a latent class analysis by HongZhe Liu, Yi Xiao, Hong Qu

“…Abstract Background Nurses, as the largest professional group in the healthcare industry, often face different psychological problems, among which depressive symptoms is the most common. This study used the latent class analysis (LCA) to classify nurses’ depressive symptoms, analyzing the differences in their second victim experience and support, psychological empowerment, and psychological detachment, providing reference for promoting nurses’ mental health. …”
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Risk Factors of Klebsiella pneumoniae Infections in Pediatric Healthcare Settings by S. A. Kuzmenko, M. A. Shmakova, E. B. Brusina

“…Klebsiella pneumoniae is a major cause of severe healthcare-associated infections in children, representing one of the six most widespread multidrug-resistant microorganisms worldwide and requiring the implementation of population-wide treatment strategies.Aim. …”
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Co-Incorporation of Green Manure and Rice Straw Increases Rice Yield and Nutrient Utilization by Cuilan Wei, Bingshuai Cao, Songjuan Gao, Hao Liang

“…Among the soil fertility indicators, TK and SOM were the most important factors influencing rice yield and N uptake. …”
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Multivalent design of the monoclonal SynO2 antibody improves binding strength to soluble α-Synuclein aggregates by Inga Petersen, Muhammad Ilyas Ali, Alex Petrovic, Anders Jimmy Ytterberg, Karin Staxäng, Monika Hodik, Fadi Rofo, Sina Bondza, Greta Hultqvist

“…Soluble aggregates are reported to be the most neurotoxic species of α-Synuclein (αSyn) in Parkinson’s disease (PD) and hence are a promising target for diagnosis and treatment of PD. …”
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Effects of liposomal bupivacaine in preoperative fascia iliac block on postoperative pain and delirium in elderly patients undergoing hip fracture surgery: a study protocol for a r... by Xiang Li, Jinbao Li, Hongjiao Xu, Weiwen Li, Zhuang Yu, Yingxiang Hao, Minjia Zheng, Xinwan Wu, Shen Liu

“…Introduction Postoperative delirium (POD) is the most common acute fluctuating mental state change after hip fractures in older adults. …”
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Opioid and non-opioid analgesic regimens after fracture and risk of serious opioid-related events by Ashley A Leech, Andrew D Wiese, Kyle Hart, Andrew J Medvecz, Avi Vaidya, Stacie Dusetzina

“…In secondary analyses, we used separate models to compare those that filled a prescription for each specific non-opioid analgesic type with opioids to those that filled only opioids.Results Of 29 489 patients, most filled an opioid prescription alone (58.4%) or an opioid and non-opioid (22.0%). …”
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REPRODUCTIVE POTENTIAL OF POTATO ACCESSIONS FROM THE VIR COLLECTION IN MURMANSK PROVINCE by S. N. Travina, Т. Е. Zhigadlo

“…According to the data of the long-term analysis of perennial agrometeorological data, the most favorable conditions for setting berries after potato self-pollination recurred every five years in the north. …”
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One-Node One-Edge Dimension-Balanced Hamiltonian Problem on Toroidal Mesh Graph by Yancy Yu-Chen Chang, Justie Su-Tzu Juan

“…The design for the network-on-chip (NoC) problem is important. One of the most famous NoC is the toroidal mesh graph <i>T_m</i>_,<i>n</i>. …”
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Progress in Our Understanding of the Cross-Protection Mechanism of CTV-VT No-SY Isolates Against Homologous SY Isolates by Grazia Licciardello, Giuseppe Scuderi, Marcella Russo, Marina Bazzano, Giuseppe Paradiso, Moshe Bar-Joseph, Antonino F. Catara

“…In the Mediterranean area, the most prevalent CTV strains are VT and T30. The VT strain includes both mild and severe isolates, some of them associated with seedling yellows (SY) syndrome. …”
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Isolation, characterization, therapeutic and prophylactic applications of a lytic bacteriophage to combat multi-drug resistance Shigella flexneri: an animal study model by Abbasi Fashami, Parisa, Pournajaf, Abazar, Amirmozafari, Nour, Hallajzadeh, Masoume, Mahabadi, Vahid Pirhajati, Saghiri, Reza, Khafri, Soraya, Golmoradi Zadeh, Rezvan, Akrami, Sousan, Asgharzadeh, Sajjad, Rajabnia, Mehdi

“…Background: Shigella (S.) flexneri is one of the most important causes of disease in children with diarrhea in Iran. …”
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Preclinical approaches in regenerative medicine for treating end-stage renal disease: a scoping review by Andrea Vigezzi, Paola Brani, Daniela Dalla Gasperina, Lorenzo Azzi, Cristina Giaroni, Davide Inversini, Giuseppe Pettinato, Matthew Massaad, Giulio Carcano, Giuseppe Ietto, Andreina Baj

“…The findings underscore the therapeutic potential of regenerative medicine in ESRD, with kidney organoids and organ-on-a-chip platforms representing two of the most advanced and translationally relevant approaches currently under investigation. …”
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Rationale and study protocol of the MAMELI Cohort study (Mapping the Methylation of repetitive elements to track the Exposome effects on health: the city of Legnano as a Living lab... by Valentina Bollati, Federica Rota, Laura Dioni, Chiara Favero, Simona Iodice, Marta Gallazzi, Andrea Spinazzè, Giacomo Fanti, Davide Campagnolo, Tiago Nardi, Davide Biganzoli, Eva Dariol, Rachele Matsagani, Mirjam Hoxha, Paola Monti, Benedetta Albetti, Letizia Tarantini, Davide Barbuto, Ester Luconi, Giuseppe Marano, Giacomo Biganzoli, Roberta Biciuffi, Patrizia Boracchi, Domenico M Cavallo, Pilar M Guerrieri, Fabio Mosca, Stefano Gustincich, Giovanni Sanesi, Luca Ferrari, Michele Carugno, Silvia Fustinoni, Angela Cecilia Pesatori, Luca Pandolfini, Michele Miragoli, Andrea Cattaneo, Elia Biganzoli

“…Several recent studies have explored how repetitive elements (REs) in the genome can be activated in response to environmental stimuli. However, most of these investigations have assumed that altered RE methylation is always detrimental to individual health. …”
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EXPRESSION OF CD44 AND CD24 MARKERS IN BIOPSY SAMPLES OF TRIPLE NEGATIVE BREAST CANCER PATIENTS BEFORE TREATMENT by S. G. Smirnova, N. V. Orlova, I. A. Smirnova, N. Yu. Dvinskikh, A. A. Charitonova, M. V. Kiseleva, I. A. Zamulaeva

“…The study of CD44 and CD24 expression in triple negative (TN) BC, which is the most aggressive breast cancer subtype, is of particular interest. …”
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Seaweed, Used as a Water-Retaining Agent, Improved the Water Distribution and Myofibrillar Protein Properties of Plant-Based Yak Meat Burgers Before and After Freeze–Thaw Cycles by Yujiao Wang, Xinyi Chang, Yingzhen Wang, Jiahao Xie, Ge Han, Hang Qi

“…LF-NMR and MRI showed that 40% seaweed addition most effectively restricted water migration, reduced thawing loss, and preserved immobilized water content. …”
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Validation of the Brazilian version of the processes of change questionnaire in weight management in adults with overweight and obesity in Brazil by Quênia de Carvalho, Paola Rampelotto Ziani, Bruno Braga Montezano, Jeferson Ferraz Goularte, Adriane R Rosa

“…Obesity increases the risk of various chronic diseases, and most people struggle to maintain weight loss in the long term. …”
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Ethics of overtreatment and undertreatment in older adults with cancer by Clark DuMontier, William Dale, Anna C. Revette, Jane Roberts, Ameya Sanyal, Neha Perumal, Eric C. Blackstone, Hajime Uno, Mary I. Whitehead, Lewis Mustian, Tammy T. Hshieh, Jane A. Driver, Gregory A. Abel

“…Lastly, consensus was reached that, in most cases, it is unethical to make a treatment recommendation without (1) formal assessment of patient frailty (e.g., via a geriatric assessment) or (2) the opportunity for the patient to share their values, goals, and preferences. …”
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Mapping tuberculosis prevalence in Africa using a Bayesian geospatial analysis by Alemneh Mekuriaw Liyew, Eyob Alemayehu Gebreyohannes, Andre Python, Archie C. A. Clements, Beth Gilmour, Peter W. Gething, Punam Amratia, Kefyalew Addis Alene

“…Abstract Background Worldwide, tuberculosis (TB) remains the leading cause of death from infectious diseases. Africa is the second most-affected region, accounting for a quarter of the global TB burden, but there is limited evidence whether there is subnational variation of TB prevalence across the continent. …”
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Fluoxetine and agomelatine mitigate anhedonic and hepatic changes in chronic restraint stress rat model by Wedad S. Sarawi, Norah K. Algarzae, Nada M. Alharbi, Ahlam M. Alhusaini, Layan M. Akkam, Reem E. Alsharidah, Latifah S. Alrasheed, Hala A. Attia, Iman H. Hasan

“…Despite being one of the body’s most resilient organs, the liver is yet susceptible to the harmful effects of chronic stress. …”
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Structure-based design of a single-chain triple-disulfide-stabilized fusion-glycoprotein trimer that elicits high-titer neutralizing responses against human metapneumovirus. by Li Ou, Steven J Chen, I-Ting Teng, Lijuan Yang, Baoshan Zhang, Tongqing Zhou, Andrea Biju, Cheng Cheng, Wing-Pui Kong, Nicholas C Morano, Erik-Stephane D Stancofski, John-Paul Todd, Yaroslav Tsybovsky, Shuishu Wang, Cheng-Yan Zheng, John R Mascola, Lawrence Shapiro, Ruth A Woodward, Ursula J Buchholz, Peter D Kwong

“…While promising subunit vaccines are being developed with prefusion-stabilized forms of the fusion glycoproteins (Fs) of RSV and PIVs, for which neutralizing titers elicited by the prefusion (pre-F) conformation of F are much higher than for the postfusion (post-F) conformation, with HMPV, pre-F and post-F immunogens described thus far elicit similar neutralizing responses, and it has been unclear which conformation, pre-F or post-F, would be the most effective HMPV F-vaccine immunogen. Here, we investigate the impact of further stabilizing HMPV F in the pre-F state. …”
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