Chemopreventive effects of vitamins in oral cancer by Dikshita Mehta, Leena Selvamary, Ramesh Kumar, Sujatha Anandan

“…The main interventions studied included various forms of Vitamin A, beta-carotene, Vitamin E, and Vitamin C.Conclusion: This review provides a synthesis of scientific evidence regarding the role of vitamins in chemoprevention, highlighting the most promising candidates in this context. Vitamins A and E demonstrate a conclusive association with oral cancer prevention, whereas the roles of Vitamins B, C, and D remain less clear and warrant further investigation.…”
Get full text

The emergence of new antigen branches of H9N2 avian influenza virus in China due to antigenic drift on hemagglutinin through antibody escape at immunodominant sites by Nan Zhang, Keji Quan, Zixuan Chen, Qun Hu, Maoshun Nie, Nuo Xu, Ruyi Gao, Xiaoquan Wang, Tao Qin, Sujuan Chen, Daxin Peng, Xiufan Liu

“…In this study, we investigated the molecular basis of the current widespread antigenic drift of H9N2 AIVs. Specifically, the most prevalent h9.4.2.5-lineage in China was divided into two antigenic branches based on monoclonal antibody (mAb) hemagglutination inhibition (HI) profiling analysis, and 12 antibody escape residues were identified as molecular markers of these two branches. …”
Get full text

Heat shock proteins gene family: Genome-wide identification in Micropterus salmoides and expression analysis under high-temperature stress by Meng Zhang, Shangjin Qiu, Yikai Li, Tianxi Fu, Jinhui Yu, Ke Ma, Yongtao Tang, Chuanjiang Zhou

“…Micropterus salmoides has become one of the most important freshwater fish cultured in China. …”
Get full text

Changes in anticoagulant prescription in a general hospital in 2008-2018 by E. B. Kleymenova, V. A. Otdelenov, M. D. Nigmatkulova, S. A. Payushchik, A. A. Chernov, O. D. Konova, L. P. Yashina, A. M. Cherkashov, D. A. Sychev

“…From 2011 to 2018, the proportion of patients with DOACs prescription increased from 1.7% to 81.5%. The most common indications for anticoagulant were ischemic stroke prevention in AF and VTE with mean rate 75.3% and 23.2%, respectively for the 2011-2018 period. …”
Get full text

Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy by Xiaoxu Zhao, Tian Shen, Shengda Cao, Ziyi Liu, Wendu Pang, Meixuan Li, Jingjing Liu, Wen Li, Yunhao Wu, Chengcheng Liu, Ming Xia, Xiaolong Fu, Cheng Cheng

“…Abstract Presbycusis, also known as age‐related hearing loss (ARHL), is a progressive auditory impairment and ranks among the most prevalent sensory disorders in the elderly population. …”
Get full text

Utilizing native nanodiscs to isolate active TRPC3 channels and expand structural analysis capabilities by Jasmin Baron, Lena Bauernhofer, Sandro Keller, Franz P. W. Radner, Carolyn Vargas, Gerd Leitinger, Lukas Bernauer, Anita Emmerstorfer-Augustin, Patrick Wiedner, Grégory Durand, Marine Soulié, Victoria Dorrer, Matthias Schittmayer, Ruth Birner-Gruenberger, Michaela Lichtenegger, Matthias Gsell, Klaus Groschner, Rainer Schindl, Oleksandra Tiapko

“…Among the extraction agents screened, dodecyl diglucoside (DDDG) and n-dodecyl-β-D-maltoside (DDM) were the most effective for extracting TRPC3. We successfully purified TRPC3 under native conditions, preserving its tetrameric structure and activity, as confirmed by electron microscopy, mass spectrometry and patch-clamp analysis. …”
Get full text

The cyclase-associated protein contributes to antifungal susceptibility and virulence in Aspergillus fumigatus by Xinyu Yang, Qian Wang, Binghan Xiao, Qiqi Wang, Weiwei Deng, Nir Osherov, Ruoyu Li, Wei Liu

“…Aspergillus fumigatus is the most prevalent pathogenic mould that contributes to high morbidity and mortality in immunocompromised patients. …”
Get full text

A Multifunctional Nanodelivery System Modified by Fusion Peptides Acts as Teriparatide Carrier for Noise‐Induced Hearing Loss Therapy by Jiawen Li, Zhuowen Hao, Fangzi Ke, Zhihui Liu, Weilong Wang, Sihui Wen, Fan Wu, Bowen Xu, Miao He, Shengyu Zou, Xiong Chen, Jingfeng Li, Zuhong He

“…Abstract Noise‐induced hearing loss (NIHL) is among the most poorly treated diseases due to irreversible damage to hair cells. …”
Get full text

Life Expectancy – The More We Know the Longer We Live? by Evgeny Andreev, Dmitry Zhdanov

“…However, life expectancy in the academic community is unexpectedly low. According to the most recent data, life expectancy of Russian academicians is only 2 years higher than for all Swedish men and 0.7 year lower than for highly educated Swedish men with non-manual occupational status. …”
Get full text

Рhotopic Negative Response for Testing the Function of Inner Retina: Registration Requirements and Comparison in the Eyes with Natural Pupil Width and in Conditions of Drug Mydrias... by V. I. Kotelin, M. O. Kirillova, M. V. Zueva, I. V. Tsapenko, A. N. Zhuravleva, O. A. Kiseleva, A. M. Bessmertny

“…The effect of pupil size on the parameters of the PhNR was most significant in the ERG with minimal flash strength and it decreases in responses to flashes of higher brightness. …”
Get full text

Pan-cancer landscape of ITGAV and its potential role in gastric cancer by Bin Ke, Peng Jin, Xue-Jun Wang, Ru-peng Zhang, Ning Liu, Gang Ma

“…The results revealed that ITGAV was variably expression in different cancers, and ITGAV had a certain prognostic and diagnostic value in most cancers, including GC. ITGAV expression was found to be related to genetic alteration, DNA methylation, immune checkpoint gene, and immune cell infiltration in multiple cancers. …”
Get full text

Improving medication adherence and viral load suppression in pediatric, adolescent, and young adult patients living with HIV using a specialty pharmacy by Timothy J. Howze, Tiffany M. Nason, Susan D. Carr, Steve M. Pate, Anderson L. Roe, Nehali D. Patel

“…Of the patients who were already ≥80% adherent, most remained that way (82.6% versus 17.4%) (p < 0.001). …”
Get full text

Unobtrusive Sleep Posture Detection Using a Smart Bed Mattress with Optimally Distributed Triaxial Accelerometer Array and Parallel Convolutional Spatiotemporal Network by Zhuofu Liu, Gaohan Li, Chuanyi Wang, Vincenzo Cascioli, Peter W. McCarthy

“…The average accuracy is 98.42%, outperforming most state-of-the-art deep learning models. The PCSN achieves the highest scores across all metrics: 98.64% precision, 98.18% recall, and 98.10% F1 score. …”
Get full text

The implementation of the mobile application “Colorectal Leakage App”, based on the Dutch Leakage Score, for early detection of anastomotic leakage after colorectal surgeries—pilot... by Meiram Mamlin, Saule Khamzina, Gulden Zhanmukanbetova, Nurlan Mukazhanov, Aidana Amangeldiyeva, Arman Kozhakhmetov

“…BackgroundColorectal cancer is the third most common malignancy globally and in Kazakhstan, with anastomotic leakage (AL) being a severe complication of colorectal surgeries. …”
Get full text

Description of the course of tuberculosis in the sources of infection and children who developed tuberculosis after exposure to the infection for different periods of time by M. F. Gubkinа, Yu. Yu. Khokhlovа, N. V. Yukhimenko, I. Yu. Petrаkovа, S. S. Sterlikovа, N. I. Evseevа

“…Regardless of the duration of exposure, the most frequent forms were tuberculosis of chest lymph nodes and focal tuberculosis. …”
Get full text

Identification of Typical Time-Series House Consumption Profiles Based on Unsupervised Learning Techniques by Marcelo Forte, Cindy P. Guzman, Lucas Pereira, Hugo Morais

“…This paper presents a comparative analysis of various clustering methods for deriving consumer electricity profiles, aiming to identify the most suitable techniques for big time-series data and to evaluate how the granularity of the data influences the final profiles. …”
Get full text

Prevalence of mineralization in the pulp chamber in patients according to CBCT data by V. A. Molokova, I. N. Antonova, V. A. Osipova

“…Their number increases with age, and in women occurs more often than in men. They were most often detected in the first molars. For a dentist, data on the prevalence of calcifications and mineralization of pulp chamber are one of the key aspects for planning high-quality root canal treatment.…”
Get full text

Assessment of quaternary aquifer pollution sensitivity using modified DRASTIC models around stressed Canal in Eastern Nile delta, Egypt by Zenhom E. Salem, Abdullah M. Attiah, Abdelazim Negm, Mohamed S. Fathy, Youssef M. Youssef

“…One- Map Removal Sensitivity Analysis (MRSA) analysis showed the Pesticide DRASTIC model was most sensitive to net recharge (1.36%) and soil media (1.0%), with moderate sensitivity to the vadose zone (0.65%), topography (0.45%), and hydraulic conductivity (0.42%). …”
Get full text

Physical activity of community-dwelling adults with traumatic spinal cord injuries in the Cape Metropole by Aeysha Gabriels, Toughieda Ismail, Lucian Bezuidenhout, Conran Joseph

“…Clinical implications: Cape Metropole’s unique SCI profile with mostly young males, results in long-term injury impacts. …”
Get full text

Impact of PM2.5 exposure on acute toxicities and survival outcomes in radiotherapy for cervical cancer by Nawapon Nakharutai, Imjai Chitapanarux, Ekkasit Tharavichitkul, Patrinee Traisathit, Pimwarat Srikummoon, Salinee Thumronglaohapun, Natthapat Thongsak, Titaporn Supasri, Phonpat Hemwan, Pooriwat Muangwong

“…Survival outcomes–including locoregional control, distant metastasis, disease-free survival, and overall survival–were estimated using Kaplan–Meier curves and Cox proportional hazards models. Most patients (90%) had locally advanced disease, and nearly 80% received brachytherapy and chemotherapy. …”
Get full text