The Safety of Non‐immunogenic Recombinant Staphylokinase in Elderly Patients With Massive Pulmonary Embolism: A Randomized Clinical Trial FORPE by Stanislav G. Leontyev, Elena B. Yarovaya, Vladimir A. Kutsenko, Oleg E. Ivlev, Anna G. Soplenkova, Andrey M. Semenov, Mikhail P. Semenov, Sergey V. Ivanov, Yulia A. Romashova, Sergey S. Markin

“…ABSTRACT Background and Aims Major bleedings are the most limiting factor of the usage of thrombolytic agents in pulmonary embolism (PE), especially in elderly patients. …”
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DART–Triple Quadrupole Mass Spectrometry Method for Multi-Target and Fast Detection of Adulterants in Saffron by Linda Monaci, Anna Luparelli, William Matteo Schirinzi, Laura Quintieri, Alexandre Verdu

“…<b>Background</b>: Different methods have been developed for detecting saffron adulteration. Most of them are time consuming and complex, and in some types of analysis, the whole untargeted dataset is combined with advanced chemometric tools to differentiate authentic from non-authentic saffron. …”
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Prevalence and Risk Factors of Asthma Among Iraq Adults: A Cross-Sectional Study by Alsajri AH, Al-Qerem W, Hammad AM, Alasmari F, Eberhardt J, Mohamed Noor DA

“…The prevalence of physician-diagnosed asthma was 10.5%. The most commonly reported asthma symptom was waking due to an attack of coughing, reported by 60.9% of participants, followed by shortness of breath triggered by dust or fumes (45.9%) and waking due to shortness of breath (36.6%). …”
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Reconsidering the management of patients with cancer with viral hepatitis in the era of immunotherapy by John Haanen, Amalia Anastasopoulou, Helen Gogas, Frosso Kostantinou, Evangelos Cholongitas, Panagiotis Diamantopoulos

“…While, the prophylactic use of modern antiviral drugs could eliminate or diminish up front the viral load in most cases, leading to cure or long-term hepatitis control. …”
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Innovative gel method: Sustainable crack healing in ceramic powder geopolymer mortars via marine actinomycetes and bioactivated carriers by Sumeyye Koseoglu, Merve Kubat, Mucteba Uysal, Elif Ozlem Arslan Aydogdu, Beyza Fahriye Aygun, Orhan Canpolat

“…The S1 +S group showed the best mechanical recovery, with compressive and flexural strengths of 42.92 MPa and 8.98 MPa, respectively, while S26 +S showed the best UPV value of 3245.44 m/s, attesting to effective internal consolidation. S13 +S showed the most balanced improvement in acetate-decomposing strains, with compressive strength of 37.20 MPa, flexural strength of 5.63 MPa, and minimized water absorption (7.44 %). …”
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In Vitro Activity of Imipenem/Relebactam Alone and in Combination Against Cystic Fibrosis Isolates of <i>Mycobacterium abscessus</i> by Madeline Sanders, Sun Woo Kim, Aditi Shinde, Danielle Fletcher-Williams, Eric Quach, Paul Beringer

“…Extracellular time-kill assays identified imipenem/relebactam + cefoxitin + rifabutin and imipenem/relebactam + cefoxitin + moxifloxacin as the most effective combinations. Conclusions: These findings suggest that imipenem/relebactam may offer a significant advancement in the management of MABS infections in PwCF. …”
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Content of macro- and microelements in the plants of Artemisia annua L., A. ludoviciana Nutt. and A. austriaca L. by О. А. Корабльова, Д. Б. Рахметов, M. І. Шанайда, O. M. Вергун, Л. В. Свиденко, В. І. Войцехівський

“…It was shown that aerial parts of the investigated plants accumulate the most important elements for the plants life, such as – K, Fe, Cu, Zn and Mn. …”
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Evaluation of multiple machine learning models predicting the results of hybrid imaging in primary hyperparathyroidism by Anna Drynda, Jacek Podlewski, Karolina Kucharczyk, Grzegorz Sokołowski, Anna Sowa-Staszczak, Alicja Hubalewska-Dydejczyk, Małgorzata Trofimiuk- Müldner

“…CONCLUSIONS: Logistic regression and RF models were the most effective in predicting radiotracer uptake in pre-operative hybrid imaging of the parathyroids, suggesting their suitability as the foundation for software to be used in clinical settings. …”
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A practical workflow to facilitate analysis of the emission dynamics of non-target BVOCs in terrestrial ecosystems by PTR-TOF-MS by Mathias Fontez, Joris Huguenin, Frédéric Jullien, Sandrine Moja, Magali Proffit, Florence Nicole

“…For this specific model experiment, we determined that normalization using the RUVr method and using and setting the MCR on a number of five components gave the most accurate results. However, this configuration is optimized for the current dataset; other experimental designs may require different normalization methods or numbers of components to achieve optimal results. …”
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Early Recurrence of Hepatocellular Carcinoma in Patients without Microscopic Vascular Invasion: Clinicopathological Characteristics and Risk Factors by Ngo HTT, Nguyen DD, Dang MX, Doan TTP, Thai TT

“…The early recurrence rate was 31.9%, with most recurrences occurring between 6- and 18-month post-surgery. …”
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Leveraging machine learning for duration of surgery prediction in knee and hip arthroplasty – a development and validation study by Benedikt Langenberger, Daniel Schrednitzki, Andreas Halder, Reinhard Busse, Christoph Pross

“…We therefore aimed (1) to identify whether machine learning can predict DOS in HA/KA patients using retrospective data available before surgery with reasonable performance, (2) to compare whether machine learning is able to outperform multivariable regression in predictive performance and (3) to identify the most important predictor variables for DOS both in a multi- and single-hospital context. …”
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Treatment with (R)-α-methylhistamine or IL4 stimulates mucin production and decreases Helicobacter pylori density in the murine stomach by Licínia Santos, Sinan Sharba, John Benktander, Stefany Ojaimi Loibman, Macarena P. Quintana-Hayashi, Mattias Erhardsson, Sara K. Lindén

“…Helicobacter pylori is the most common gastric pathogen. H. pylori is prone to develop antibiotic resistance and recurrence after therapy makes treatment problematic. …”
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Diagnostic Possibilities of Optical Coherent Tomography of the Retina during Compression in the Chiasm-Sellar Region by N. A. Gavrilova, E. E. Ioyleva, N. S. Gadzhieva, O. E. Tishchenko, N. Y. Kutrovskaya, A. V. Kuz’mina, A. V. Zinov’eva

“…Today optical coherence tomography (OCT) of the retina is one of the most informative methods for diagnosing pathology of the retina and optic nerve. …”
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Provenance Variation in Seed, Seedling, and Early Growth Traits of Red Jabon (Neolamarckia macrophylla): An Endemic Species From Sulawesi and Maluku, Indonesia by Dede J. Sudrajat, Evayusvita Rustam, null Yulianti, Ratna Uli Damayanti, Nurin Widyani, null Nurhasybi, Kurniawati P. Putri, Y. M. M. Anita Nugraheni, null Danu, Eliya Suita, Mohammad Agus Salim, Muhammad Zanzibar, Naning Yuniarti, Vivi Yuskianti

“…Provenances were significantly different (p<0.05) for most fruit, seeds, seedlings, and early growth traits, except for seed weight, seedling sturdiness quotient, seedling height, tree diameter at 1 year, tree survival at 4 years, and pilodyn penetration. …”
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The Distance to the Magellanic Stream: Constraints from Optical Absorption along Stellar Sight Lines by Sapna Mishra, Andrew J. Fox, J. V. Smoker, Scott Lucchini, Elena D’Onghia

“…For the other region, we set a firm lower limit of 20 kpc and a tentative lower limit of 55 kpc from the most distant star, but deeper spectra are needed to confirm this. …”
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Targeting Streptococcus pyogenes atpF protein for multi-epitope vaccine development: a genomics-driven immunoinformatics strategy by Manisha Agarwal, Sanjeeb Handique, Sanchaita Rajkhowa, Abhichandan Das, Debashis Panda, Sami A. Al-Hussain, Magdi E.A. Zaki

“…Molecular modeling identified SM1 as the most promising candidate, demonstrating superior immune receptor binding affinity and flexible epitope interactions, facilitating effective antibody recognition. …”
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Specific Treatment of Elderly Pilgrims on Hajj According to the Hadith ; The Approach of Mukhtalif Ahadis by Masyithah Mardhatillah

“…Most of Indonesian hajj pilgrims are elderly due to approximately 23 years waiting period. …”
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Enhancing lipid accumulation in Tetraselmis sp.: integrating nitrogen deprivation and glucose supplementation for biofuel production by H. M. V. Udayantha, Seung-Hyeon Kim, Yu Chen, Jinxia Long, S. D. N. K. Bathige, Kyung-Il Park

“…NDM+G, with 2 mg/mL glucose, was the most effective medium for lipid accumulation in Tetraselmis sp., with lipid levels peaking significantly (p < 0.05) at 79.8% on day 6 post-glucose supplementation. …”
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PROS1‐MERTK Axis Drives Tumor Microenvironment Crosstalk and Progression in Papillary Thyroid Microcarcinoma by Wenqian Zhang, Ye Zhang, Zhu Liu, Zhiyuan Wang, Huaqin Wang, Xiaoyu Ji, Hongyue Su, Fan Yang, Lirong Yan, Ying Xu, Hao Zhang, Wei Sun

“…Abstract The incidence of papillary thyroid carcinoma (PTC) has been rising annually, with papillary thyroid microcarcinoma (PTMC) accounting for more than half of the cases. While most PTMCs exhibit indolent growth and a favorable prognosis, some undergo clinical progression with poor outcomes. …”
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Research progress on influencing factors and risk prediction models of frailty in elderly stroke patients (老年脑卒中患者衰弱影响因素及风险预测模型的研究进展)... by YU Yue (余月)

“…The results show that multiple factors lead to the occurrence of frailty in elderly stroke patients. Most of the currently constructed models lack effective external validation. …”
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