Machine learning developed an immune evasion signature for predicting prognosis and immunotherapy benefits in lung adenocarcinoma by Dongxiao Ding, Gang Huang, Liangbin Wang, Ke Shi, Junjie Ying, Wenjun Shang, Li Wang, Chong Zhang, Maofen Jiang, Yaxing Shen

“…BackgroundLung adenocarcinoma (LUAD) is one of the most common cancers worldwide and a major cause of cancer-related deaths. …”
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Baseline sensitivity of Echinochloa glabrescens to florpyrauxifen-benzyl on a regional scale: A case study of Jiangsu Province, China by Chen Guo-qi, Chen Yang, Aatiqa Masoom, Wu Jia-jun, Wei Hai-yan

“…Florpyrauxifen-benzyl is one of the most important herbicides used in rice production throughout the world, and has been used for 5 yr in China. …”
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Comparative analysis of differentially expressed genes and transcripts in the ovary of yak in estrus and anestrus by Chongfa Yang, Yahua Yang, Bingzhu Zhao, Enyu Gao, Hao Chen, Yang Li, Junyuan Ma, Jine Wang, Songming Hu, Xiaochen Song, Ying Chen, Gengsacairang Yang, Shengdong Huo, Wenxue Luo

“…Since most yaks have a long postpartum anestrus period, postpartum anestrus is the main factor affecting the reproductive efficiency of yaks. …”
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Difficulties in Manipulating the Female Artificial Urinary Sphincter Pump: Prevalence and Management by Alexandre Dubois, Valentine Lethuillier, Claire Richard, Camille Haudebert, Juan Penafiel, Caroline Voiry, Magali Jezequel, Emmanuelle Samson, Louis-Paul Berthelot, Lucas Freton, Juliette Hascoet, Andrea Manunta, Benoit Peyronnet

“…Conclusions Difficulties in manipulating the pump are relatively common among female AUS patients. Most of these difficulties can be resolved through repeated patient education and careful follow-up. …”
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From Chemistry to Pharmacology: Exploring the Anti-Inflammatory and Antioxidant Potential of Novel Dexketoprofen Amide Derivatives by Marko Karović, Miloš Nikolić, Nikola Nedeljković, Marina Vesović, Marina Nikolić, Marijana Anđić, Nevena Lazarević, Vladimir Jakovljević, Jelena Nedeljković, Sanja Đaković, Jelena Bošković, Vladimir Dobričić

“…Among the analyzed molecules, derivatives <b>2</b> and <b>4</b> exhibited the most potent in vivo anti-inflammatory activity, showing effects comparable to those of the parent compound dexketoprofen. …”
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To the Question of the Relevance of Statistics of Information and Communication Technologies in the Context of the Digital Transformation of the Economy by M. Y. Karyshev

“…To solve this problem, an integral index was developed, which included the most significant indexes of each of the groups (selected by experts). …”
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Bloodstream infections: trends in etiology and antimicrobial resistance in 10 years in Eastern Nepal by Basudha Khanal, Lok Bahadur Shrestha, Abhilasha Sharma, Shraddha Siwakoti

“…Staphylococcus aureus (44%, n = 4,210) was the most common organism, followed by Acinetobacter baumannii (18%, n = 1,762), Pseudomonas aeruginosa (9%, n = 820), Klebsiella pneumoniae (8%, n = 752) and Enterococcus spp (8%, n = 741). …”
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Placebo and Nocebo Effects in Motor Performance: An Overview of Reviews by Cayque Brietzke, Wesley Alves Ribeiro, Paulo Estevão Franco‐Alvarenga, Raul Canestri, Ìtalo Vínicius, Gustavo Vasconcelos, Julio Cesario, Nelson Carvas Junior, Vitor de Salles Painelli, Flávio Oliveira Pires

“…Conclusion We found varied placebo and nocebo effects on motor performance, likely due to the poor quality of the methodology used by most reviews, highlighting the need for well‐conducted systematic reviews on the placebo and nocebo phenomena.…”
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Does optimized adherence support improve treatment outcomes in RR / MDR-TB patients on 18-20 months regimen in Tbilisi, Georgia? by Tinatin Jomidava, Mohammed Khogali, Yuliia Sereda, Zaza Avaliani, Malkhaz Davitashvili, Mikheil Madzgharashvili, Nestan Tukvadze, Lali Chaphurishvili, Mamuka Chincharauli, Maia Kipiani

“…Results: Of 221 RR/MDR-TB, most patients were male (76%, N = 167) with a mean age of 41 ± 14 years. …”
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Genome-Wide Identification and Heat Stress-Induced Expression Profiling of the <i>Hsp70</i> Gene Family in <i>Phoebe bournei</i> by Yiming Lin, Yan Jiang, Zhuoqun Li, Yuewang Niu, Chenyu Gong, Xin He, Shipin Chen, Shijiang Cao

“…Under high-temperature stress, all nine genes were differentially upregulated, and most of these genes belonged to subfamilies II and III, indicating that these two subfamilies have strong potential for heat resistance. …”
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Optimization of a sustainable composition of fine-grained concrete for 3D-printing with partial substitution of sand with fly ash and slag waste by Murat A. Rakhimov, Zulfiya A. Aubakirova, Aliya K. Aldungarova, Ignacio Menéndez Pidal de Navascués, Zhangazy N. Moldamuratov

“…Recent studies confirm the potential of such waste as a partial substitute for conventional sand in concrete mixtures. However, most research focuses on conventional concrete and does not consider the specific requirements for rheological properties and interlayer adhesion, which are critical for 3D printing technology. …”
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Targeting RPS6KC1 to overcome enzalutamide resistance in prostate cancer by Fu-Hao Ji, Yu-Hang Qian, Xiu-Chen Guo, Hai-Hong Liao, Jia-Cheng Huang, Zi-Han Xu, Ming-Ming Yu, Yan-Yuan Wu, Jie-Wen Bao, Hao-Jie Chen, Yong-Jiang Yu, Lin Wang

“…Abstract The androgen receptor signaling inhibitor enzalutamide (Enz) is one the primary therapeutic drugs for advanced prostate cancer (PCa). Nevertheless, most of patients ultimately develop resistance to Enz. …”
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In Vitro Evaluation of the Antibacterial Effect and Influence on the Bacterial Biofilm Formation of Glutamic Acid and Some Structural Analogues by Octavia-Laura Oancea, Cristina Nicoleta Ciurea, Anca Delia Mare, Adrian Man, Ruxandra Stefanescu, Aura Rusu

“…<b>Results</b>: GLN did not demonstrate an inhibitory capacity at the maximum tested concentration (2.86 mg/mL); GLA showed inhibitory activity at 1.76 mg/mL and 0.88 mg/mL; MSG inhibited the growth of all bacterial strains at 112 mg/mL; GLADE had the most promising results on all bacterial strains (MICs of 12.75 mg/mL and 25.5 mg/mL). …”
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Efficacy of photobiomodulation for the prevention and treatment of chemotherapy-induced oral mucositis in pediatric patients with hematologic cancers: a randomized clinical trial by Fatemeh Lavaee, Fahimeh Rezazadeh, Ali Amanati, Asma Sookhakian, Mohammad Amin Amiri, Navid Dehghani, Kiarash Fereidouni

“…Abstract Background Oral mucositis (OM) is a debilitating treatment-related complication that affects most children undergoing chemotherapy. This dual-arm clinical trial aimed to evaluate the efficacy of photobiomodulation (PBM) for prevention and photodynamic therapy (PDT) using indocyanine green (ICG) and low-level laser for treating methotrexate (MTX)-induced OM in pediatric patients with hematologic cancers. …”
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Imaging Features and Clinical Characteristics of Granular Cell Tumors: A Single-Center Investigation by Hui Gu, Lan Yu, Yu Wu

“…<b>Background/Objectives:</b> Granular cell tumors (GCTs) are rare neurogenic tumors with Schwann cell differentiation. Although most are benign, 1–2% exhibit malignant behavior. …”
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Genome Mining of Terpene Synthases from Fourteen <i>Streptomyces</i> Strains by Yuanyuan Li, Xi Xiang, Zhiyuan Ren, Rui Wang, Minghui Xie, Gen Li, Xiaohui Yan, Zhilong Zhao, Zixin Deng, Min Xu, Anwei Hou

“…Terpenoids are the most structurally diverse class of natural products (NPs). …”
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Selective Dry Cow Therapy in Modern Dairy Management: Balancing Udder Health and Antimicrobial Stewardship by Ionela Delia Ut, Daniel Ionut Berean, Liviu Marian Bogdan, Simona Ciupe, Sidonia Gog Bogdan

“…Among these methods, SCC has proven to be the most economically viable and best suited for practical use, while its combination with DSCC has been shown to significantly enhance diagnostic accuracy. …”
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Combining Plant Bioactives With Antibiotics for Enhanced Antibiofilm Activity Against Uropathogenic Staphylococcus spp. and Cytotoxicity Evaluation by Ulrich Joël Tsopmene, Christian Ramsès Kuate Tokam, Larissa Yetendje Chimi, Nathalie Boulens, Eric Allémann, Florence Delie, Clautilde Teugwa Mofor, Jean Paul Dzoyem

“…Urinary tract infections (UTIs) are one of the most important causes of morbidity and healthcare spending. …”
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Mechanized and irrigated coffee cultivation promotes physical subsurface constraints in Oxisols by Katherine Martinez Escobar, Laís Maria Rodrigues Silva, Keise Duarte Bacelar de Morais, Júlio César Lima Neves, Teogenes Senna de Oliveira

“…Total porosity (TP), mean penetration resistance (PRmean), volumetric moisture (θ) at 100 kPa (θ 100 kPa) and 300 kPa (θ 300 kPa) tensions, particle density (PD), and granulometric fractions (clay, fine sand, and coarse sand) were among the most influential attributes. Total porosity and PRmean demonstrated the existence of compaction in the tractor wheel tracks, particularly in the 0.00-0.20 m layer. …”
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Meta-analysis on intervention effects of exercise on Chinese children and adolescents with mobile phone dependence by Long Chen, Yilin Ren, Pingting Zhu, Yahui Yang, Fengshu Zhu

“…The protocol of this systematic review was registered in PROSPERO (CRD42024543710).Results(1) Aerobic exercise showed a significant intervention effect on mobile phone dependence in children and adolescents in the intervention content subgroups but was not statistically significant in the combined exercise subgroups. (2) Exercise demonstrated a large effect size intervention effect on mobile phone dependence in children and adolescents. (3) Regarding mobile phone dependence in children and adolescents, the intensity of the intervention was divided into three subgroups: medium, moderate to high, and low. (4) The greatest intervention effect on mobile phone dependence was observed with a three-times-weekly intervention frequency. (5) Exercise lasting between 8 to 30 weeks showed a positive intervention effect on mobile phone dependence, with the most effective intervention occurring around 12 weeks. (6) The following order reflected the effect of the intervention duration on children and adolescents’ mobile phone dependence: 40–45 min, 20–30 min, ≥90 min, and 60 min.Conclusion(1) Children and teenagers with cell phone addictions can benefit from exercise in reducing their symptoms; (2) the content, intensity, period, frequency and duration of exercise all exert a varying degree of influence on the intervention effect of exercise on mobile phone dependence in children and adolescents. …”
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