High MRPS23 expression contributes to hepatocellular carcinoma proliferation and indicates poor survival outcomes by Meng Pu, Jianlin Wang, Qike Huang, Ge Zhao, Congcong Xia, Runze Shang, Zhuochao Zhang, Zhenyuan Bian, Xishegn Yang, Kaishan Tao

“…Hepatocellular carcinoma is one of the most prevalent neoplasms and the leading cause of cancer-related mortality worldwide. …”
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Ionotropic Receptor Genes in Fig Wasps: Evolutionary Insights from Comparative Studies by Hui Yu, Xiaojue Nong, Weicheng Huang, Ling Yang, Chantarasuwan Bhanumas, Yongmei Xiong, Seping Dai

“…Compared to ORs and GRs in fig wasps, gene sequences in most IR orthologous groups are more conserved between genera, with the lowest sequence similarity in 10 orthologous groups (including three IRco) exhibiting above 58.5%. …”
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A Multidisciplinary and Longitudinal Framework for Enhancing Innovation Efficiency in Healthcare Systems by Szentpeteri JL, Szabo P, Liber N, Pandur E, Deak M, Csutak A, Sik A

“…Several obstacles hinder most innovative efforts in hospitals. Often, supposed innovative solutions fail to address existing problems, which do not translate into market-ready solutions and lack economic or social value. …”
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Efficient Machine Learning Models for Solar Radiation Prediction Using Ensemble Techniques: A Case Study in Low-Rainfall Arid Climates by Jimmy Aurelio Rosales Huamani, Uwe Rojas Villanueva, Christian Leonardo Rosales Ventocilla, Jose Luis Castillo Sequera, Jose Manuel Gomez Pulido

“…From this, dimensionality reduction was carried out using the Principal Component Analysis (PCA) technique, obtaining the 8 most appropriate representative variables for the prediction of solar radiation using different Machine Learning (ML) models. …”
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SELECTING THE OPTIMAL SCENARIO FOR THE SIMULTANEOUS APPLICATION OF DIAMOND WIRE CUTTING AND CHAINSAW MACHINES IN DIMENSIONAL STONE MINES USING SECA MULTI-CRITERIA DECISION-MAKING M... by Abbas Amou, Majid Ataee-pour, Satar Mahdevari

“…Currently, diamond wire cutting is used in most dimensional stone mines to extract stone blocks. …”
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Microglia-derived ADAM9 promote GHRH neurons pyroptosis by Mad2L2-JNK-caspase-1 pathway in subarachnoid hemorrhage by Jian Mao, Yun Bao, Fan Liu, Qiyun Ye, Junxiang Peng, Jing Nie, Lijun Huang, Yonghong Liao, Yiheng Xing, Dongyang Wu, Ke Wang, Wenfeng Feng, Songtao Qi, Jun Pan, Binghui Qiu

“…A total of 683 proteins were identified, including 39 upregulated proteins in the GHD group. ADAM9 was most highly associated with GHD. In vivo, ADAM9 colocalized with M1 microglia markers, GH and cognitive ability of mice decreased significantly, and microglia secreted ADAM9 significantly. …”
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Selection of differentiated maturity genotypes of Coffea canephora by João Felipe de Brites Senra, Viviane Alexia Correia Silva, Marlon Dutra Degli Esposti, Adésio Ferreira, Idalina Sturião Milheiros, Isabela Bolari Ramos, Rosana Gomes de Oliveira, Lorran Marques Benevenute

“…Genotypes 25, 26, 73, 93, and 100 could be used for early maturing varieties, whereas genotypes 155 and 189 could be used for late-maturing varieties. The most promising genotypes for composing a variety, regardless of the maturation period, were 20, 39, 90, 112, and 190, as these were among the five best genotypes ranked in the three selection processes, demonstrating that they added superior desired morphoagronomic characteristics. …”
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PCSK9 Inhibitors in Clinical Practice: Experience of a Specialized Lipid Center by A. V. Blokhina, A. I. Ershova, A. S. Limonova, O. V. Kopylova, A. N. Meshkov, O. M. Drapkina

“…Among patients with other hyperlipidemias, 74.1% of patients with very high CVR was achieved the target LDL-C level <1.4 mmol/l.Conclusion: In a specialized lipid center, PCSK9 inhibitors are prescribed to patients with high or very high CVR, most of whom are FH patients. The effectiveness of the use of PCSK9 inhibitors in real-world practice is comparable to the results of clinical trials.…”
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Record‐Breaking Far‐Red Silicon Quantum Dots LEDs Enabled by Solvent Engineering: Toward Superseding Perovskite Quantum Dots by Li Wang, Yuto Wada, Honoka Ueda, Temmaru Hirota, Kota Sumida, Yuito Oba, Ken‐ichi Saitow

“…Most quantum dots (QDs) contain either toxic elements, which are health and environmental hazards, or costly precious metals. …”
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Towards ROXAS AI: automatic multi-species ring boundaries segmentation as regression in anatomical images by Marc Katzenmaier, Marc Katzenmaier, Vivien Sainte Fare Garnot, Jan Dirk Wegner, Georg von Arx, Georg von Arx

“…However, the reliability and accuracy of automatic cell and ring detection are key to efficient QWA data production.MethodsIn this paper, we target automatic ring segmentation and deliberately focus on the most challenging case, circular ring structures in arctic angiosperm shrubs with partly very narrow and wedging rings. …”
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Multi-transcriptomics predicts clinical outcome in systemically untreated breast cancer patients with extensive follow-up by Thi T. N. Do, Ines Block, Mark Burton, Kristina P. Sørensen, Martin J. Larsen, Anne Marie Bak Jylling, Bent Ejlertsen, Anne-Vibeke Lænkholm, Qihua Tan, Torben A. Kruse, Mads Thomassen

“…In the clinical setting, very high sensitivity may be requested. In the most stringent clinical setting with a sensitivity of 99%, the integrated dataset also outperformed the others with a specificity of 41% compared to 0%, 9% and 28% for mRNAs, lncRNAs and miRNAs, respectively. …”
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Epidemiological findings of ocular dermoid in dogs and cats: 50 cases (2007-2024) by João A.T. Pigatto, Luísa S. Cargnin, Alana P. Melo, Rafaella S. Rocha, Maria E.M. Franceschini, Natália P. Méndez, Maiara P. Seibel, Marina A. Martins, Alessandra F. Silva, Luciana Sonne

“…It is possible to conclude that ocular dermoids most frequently affect young, mixed-breed dogs and Shih Tzus. …”
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Electrical stimulation of the dorsolateral prefrontal cortex inhibits vestibular signalling in humans: A BOLD fMRI study by Brendan McCarthy, Donggyu Rim, Gianni Sesa-Ashton, Lewis S. Crawford, Tye Dawood, Luke A. Henderson, Vaughan G. Macefield

“…Objective: Given that both vestibular afferents and dlPFC efferents project to the insular cortex, it was reasoned that the insula is the most likely area for the top-down inhibitory interaction to take place. …”
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A systematic review of remote sensing technologies and techniques for agricultural insect pest monitoring: lessons for locustana pardalina (Brown Locust) control in South Africa by Kuselwa Mpisane, Mahlatse Kganyago, Cilence Munghemezulu, Cilence Munghemezulu, Roger Price, Lwandile Nduku

“…Furthermore, findings revealed that MODerate resolution Imaging Spectroradiometer (MODIS), Landsat 7 Enhanced Thematic Mapper Plus (ETM+) and Landsat 8 Operational Land Imager (OLI) and The Thermal Infrared Sensor (TIRS) are mainly used sensors to detect and monitor the impact of insect pests on vegetation. Most studies reported that insect pests have been detected in forests and croplands, with newer sensors such as Sentinel-2 MultiSpectral Instrument and PlanetScope holding potential for systematic assessments in the future. …”
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Capacity-building strategies that support correctional and justice health professionals to provide best-evidenced based healthcare for people in prison: a systematic review by Monique Hooper, Claudia Virdun, Jane L. Phillips

“…Results Of the 20 included articles, the highest level of evidence (level III) was generated by a mixed methods study, with most (n = 17) generating low-level (Level IV) evidence. …”
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Demographics and outcomes of acute type A aortic dissection in young adults in southeastern China: impact of syndromic heritable thoracic aortic disease by Xin-fan Lin, Hang-qi Gao, Qing-song Wu, Yu-ling Xie, Liang-wan Chen, Lin-feng Xie

“…Among them, only 16.0% were aware of their condition prior to the occurrence of ATAAD. Most patients underwent extensive arch procedures and in-hospital mortality rate of patients was 14.2%, which was higher in the HTAD group than in the non-HTAD group (20.0% vs. 11.0%, p = .142). …”
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Machine learning models integrating dietary data predict all-cause mortality in U.S. NAFLD patients: an NHANES-based study by Pinchu Chen, Yao Li, Chenfenglin Yang, Qifan Zhang

“…Despite the critical role of diet in disease progression, most existing prognostic models for NAFLD fail to incorporate dietary factors. …”
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Comparative Analysis of the Impact of Built Environment and Land Use on Monthly and Annual Mean PM_2.5 Levels by Anjian Song, Zhenbao Wang, Shihao Li, Xinyi Chen

“…Building density and parking lots density demonstrate strong explanatory power for most months and exhibit significant interactions with other variables. …”
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Effect of Different Treatments on Seed Germination and Seedling Growth of Burmese Grape (Baccaurea sapida Muell. Arg.) by N. T. Sherpa, A. Chakraborty, N. Bhowmick, M. P. Devi, N. Sahana, S. Subba

“…Among the minor fruit crops, Burmese grape (Baccaurea sapida Muell. Arg.) was one of the most popular and potential minor fruit. The plants were propagated through seeds and seeds were recalcitrant in nature. …”
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Video and Online Courses in the Educational Process of Plekhanov Russian University of Economics: opportunities, advantages and problems for students and professors by A. A. Dokukina, D. A. Shtykhno

“…Identified factors of the greatest influence on the perception of online and video tools by students and lecturers at PRUE reveal several difficulties concerning the development of educational technologies. However, they are mostly. Appropriate increase of the online component in the structure of academic discipline, the offer of various forms of interactive, mastery of the skills of applying the latest technical achievements represent today the most important elements of the progressiveness of the higher education. …”
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