Low-level viremia and subsequent virologic failure among people living with HIV: a retrospective cohort study in China by Yuting Tan, Wu Zheng, Songjie Wu, Dingyuan Zhao, Yanmeng Feng, Shi Zou, Qianhui Chen, Jie Liu, Heng Tang, Ke Liang

“…Of them, 18,052 received the first line ART, 1103 received the second line ART, and 963 received the third line ART. 2497 (13.8%) PLWH on first line, 189 (17.1%) PLWH on second line and 100 (10.4%) PLWH on third line ART experienced LLV, respectively.The LLV level between 51 and 199 copies/ml was the most common in both three groups. CD4 count < 200 cells/µL and older age at ART initiation were associated with higher risk of LLV among all PLWH and PLWH receiving the first line ART, and protease inhibitors (PIs) using was associated with the higher risk of LLV among all PLWH. …”
Get full text

Identification of key molecular targets for stachyose in hepatocellular carcinoma: focus on STAT3 and FN1 by Haihua Chen, Xianyou Wang, Jiongcheng Ying, YuQin Huang, Yuxi Liu, Yifu Feng, Binbo Fang, Binbo Fang

“…Background and objectiveHepatocellular carcinoma (HCC) ranks among the most prevalent malignancies on a global scale. Stachyose (STA), an oligosaccharide widely present in legumes, has demonstrated various biological activities, including improving gut microbiota, anti-oxidative stress, and anti-tumor proliferation. …”
Get full text

Neurotoxicity associated with cancer chemotherapy: the first study in the Palestinian healthcare system by Roqaya Warrad, Aya Abushar, Abdullah Qubbaj, Sultan Mosleh, Razan Odeh, Ahmad Abuhassan, Ramzi Shawahna

“…The median age was 56.9 years, with the majority being female (113 out of 196; 57.7%) and diagnosed with solid cancers (140 out of 196; 71.4%). The most common agents utilized were fluorouracil/5-FU (108 patients; 55.1%) and oxaliplatin (96 patients; 49.0%). …”
Get full text

High genotypic diversity of Rhinoviruses obtained from Tunisian children with severe acute respiratory infection by Sondes Haddad-Boubaker, Khaoula Mefteh, Chaima Mejri, Aida Bouaffsoun, Awatef El Moussi, Ilhem Boutiba, Khaled Mnif, Amin Slim, Amel Kechrid, Hanen Smaoui

“…HRV-A101 and HRV-C45 were the most frequently detected types. Conclusions: This study revealed, for the first time, the high HRV diversity in Tunisia, a North-African region. …”
Get full text

Reliability of differential time to positivity technique for diagnosing catheter-related bloodstream infections: a retrospective analysis by Álvaro Irigoyen-von-Sierakowski, Marta Díaz-Navarro, Andrés Visedo, María Jesús Pérez-Granda, Pablo Martín-Rabadán, Patricia Muñoz, María Guembe

“…DTTP is a conservative technique that might help to diagnose C-RBSI mostly in situations where catheter removal cannot be achieved. …”
Get full text

Design of Double-Loop Current Transformer Based on Magnetic Field Incomplete Cancellation by Wenbo Li, Xiaojun Tang, Youshui Lu, Ling Yan, Yi Wu, Mingzhe Rong

“…Due to continuous improvement of current level to be measured in the power system, ordinary single-loop magnetic core structure cannot meet industrial needs of wide measuring range with high accuracy, while it even has a magnetic saturation problem when measured current is reaching the limit. Most existing methods expand measuring range and increase antisaturation ability of the magnetic core by either opening an air gap in the magnetic core or increasing number of turns of primary and secondary windings, but it will bring additional problems such as volume and heat dissipation of the transformer. …”
Get full text

Factors associated with the decision to receive bivalent COVID-19 booster vaccination among health care personnel by Nicholas M. Mohr, Ian D. Plumb, Eliezer Santos León, Karisa K. Harland, Anusha Krishnadasan, Utsav Nandi, Karin F. Hoth, Howard A. Smithline, David A. Talan

“…Compared with those who had not received the booster, the factors most likely to be reported to be important were concerns about contracting COVID-19 (84.0% of those who had received the bivalent booster vs. 47.5% of those who had not, difference 36.6% points (PP), 95% confidence interval [CI] 32.1 to 41.1%), spreading infection to family members (89.2% vs. 62.8%, difference 26.3 PP, 95% CI 22.3 to 30.4%), and spreading infection to colleagues at work (85.5% vs. 59.4%, difference 26.1 PP, 95% CI 21.7 to 30.5%). …”
Get full text

The Energy Footprint in the EU: How CO₂ Emission Reductions Drive Sustainable Development by Dariusz Sala, Oksana Liashenko, Michał Pyzalski, Kostiantyn Pavlov, Olena Pavlova, Karol Durczak, Roman Chornyi

“…The findings show that total CO₂ emissions in the EU have decreased since 1990; however, the rate of reduction varies across sectors and member states. The most substantial decreases have been recorded in the energy sector, while industrial processes and agriculture show slower progress. …”
Get full text

Particular sequence characteristics induce bias in the detection of polymorphic transposable element insertions by Verneret, Marie, Le, Van Anthony, Faraut, Thomas, Turpin, Jocelyn, Lerat, Emmanuelle

“…Despite the development of numerous bioinformatic programs, identifying the most effective tool is challenging due to non-overlapping results and varying efficiency across studies. …”
Get full text

Immune Cell Proteins and Parkinson's Disease: A Mendelian Randomization Analysis of Causal Associations by Haining Li, Jianhang He, Tingting Xuan, Shue Gu, Xiaoyan Niu, Yazhou Ren, Xiuping Zhan, Jiang Cheng

“…Parkinson's disease (PD) is the second most common neurodegenerative disease, with potential immunoregulatory abnormalities. …”
Get full text

13-valent Pneumococcal Conjugate Vaccine and Haemophilus Influenzae-Tetanus Toxoid Conjugate Vaccine in Patient with Systemic Juvenile Idiopathic Arthritis Receiving Tocilizumab: C... by Ekaterina I. Alekseeva, Dar’ya D. Van’kova, Tatyana M. Dvoryakovskaya, Kseniya B. Isaeva, Rina V. Denisova, Anna V. Mamutova, Aleksandra M. Chomahidze, Nikolay A. Mayanskiy, Natalya E. Tkachenko, Maria V. Kurdup, Tatyana V. Radygina, Irina V. Zubkova

“…Respiratory infections mortality is 2–5 times higher in adults with rheumatoid arthritis than in overall population. The most frequent infectious complications in patients receiving Tocilizumab (first-line drug for treatment of patients with systemic juvenile idiopathic arthritis (SJIA)) are pneumonia and acute sinusitis. …”
Get full text

Effects Of 6-Week Telerehabilitation Exercise Programme On Chronic Non-Specific Neck Pain In Women: A Pilot Randomized Controlled Trial [version 1; peer review: 1 approved, 2 appro... by Mohammad Nayel Aqil Khan, Zaina Zahur Ahmed, Kalyana Chakravarthy Bairapareddy

“…Background Chronic non-specific neck pain is one of the most prevalent musculoskeletal disorders affecting work and lifestyle. …”
Get full text

Effect of Low dose Isotretinoin on Lipid Profile and Liver enzymes in Acne Patients: A Cross Sectional Study by Ayush Jha, Rima Shrestha, Anupa Khadka, Ashmita Wagle

“… Introduction: Oral isotretinoin remains the most clinically effective anti-acne therapy. However, a myriad of adverse effects are associated with isotretinoin use. …”
Get full text

Advances in immunotherapy for uveal melanoma: enhancing efficacy and overcoming resistance by Jian Song, Jian Song, Pei Mou, Guo-Ge Song, Liang Chen, Liang Chen, Yu-Qing Chen, Rui-Li Wei

“…Uveal melanoma (UM) is the most common primary intraocular malignancy in adults, presenting a significant clinical challenge due to its high metastatic potential and limited response to conventional systemic therapies. …”
Get full text

Algılanan İslamofobi’ Ölçeğinin Norveç’te Yaşayan Cami ve Dini Dernek Üyeleri Üzerinde Uygulanması/The Implementation of the “Perceived Islamophobia Scale” on The Mosque and Religi... by Musa Gelici

“…Participants emphasized the impact of media most strongly. Negative media representations of Muslims appear to be influential, particularly among women and individuals aged 31–45, who reported higher levels of Islamization fear. …”
Get full text

Do Hungarian multiple sclerosis care units fulfil international criteria? by Zsófia Kokas, Dániel Sandi, Zsanett Fricska-Nagy, Judit Füvesi, Tamás Biernacki, Ágnes Köves, Ferenc Fazekas, Adrienne Jóri Birkás, Gabriella Katona, Krisztina Kovács, Dániel Milanovich, Enikő Dobos, István Kapás, Gábor Jakab, Tünde Csépány, Erzsébet Bense, Klotild Mátyás, Gábor Rum, Zoltán Szolnoki, István Deme, Zita Jobbágy, Dávid Kriston, Zsuzsanna Gerócs, Péter Diószeghy, László Bors, Adrián Varga, Levente Kerényi, Gabriella Molnár, Piroska Kristóf, Zsuzsanna Ágnes Nagy, Mária Sátori, Piroska Imre, Szilvia Péntek, Péter Klivényi, Zsigmond Tamás Kincses, László Vécsei, Krisztina Bencsik

“…In 2019 multiple sclerosis care unit criteria were developed, emphasizing personnel and instrumental requirements to provide most professional care. However, no survey was conducted assessing the real-world adaptation of these criteria.…”
Get full text

Statistical analysis of the financial state of the banking sector by O. G. Tretyakova, T. I. Chinaeva

“…The correlation-regression analysis of the  factors influencing the formation of the profit of the banking sector  showed that the most significant value is the volume of loans.  Quantitative measurement of the influence of this factor is the basis  for further analysis of the financial sector of the economy,  construction of forecast calculations.…”
Get full text

Genome of Kumamoto Oyster Crassostrea sikamea Provides Insights Into Bivalve Evolution and Environmental Adaptation by Sheng Liu, Youli Liu, Ximing Guo, Naoki Itoh, Guangqiu Chang, Zhihua Lin, Qinggang Xue

“…Among the 768 genes showing selection signals between natural populations of Japan and China, genes related to stress response are most enriched, suggesting responding to environmental stress is critical for local adaptation. …”
Get full text

Hybrid ML-based predictive modeling and GUI development of calcium aluminate cement hydration and strength optimization for advanced and durable construction applications by Muwaffaq Alqurashi

“…Sensitivity analysis highlighted porosity as the most influential factor (mean permutation importance = 1.124 ± 0.094, z-score = 2.26), followed by bound water (Corr = 0.87). …”
Get full text

The Issues of Improving the Inclusive Education System in Uzbekistan by L. S. Makhmutkhodjaeva

“…Thus, we conclude that the social inclusion of children and adults with disabilities requires broad systemic changes and a multisectoral approach that removes institutional and structural barriers, allowing persons with disabilities to meet their basic needs related to health, rehabilitation, economic and social security as well as learning and skills development within living in their communities.In our conditions, which are unfavorable for the most independent life of disabled people, reducing the degree of state responsibility for the well-being of citizens with disabilities is fraught with high social risks. …”
Get full text