Impact of the aldehyde dehydrogenase 2 (ALDH2) gene testing on alcohol drinking behaviors among the Chinese Han population: study protocol of a single-center, open-label, randomize... by Dongli Lu, Yingneng Wen, Kaijun Liao, Qiulian Lu, Shiqin Wu, Lin Fang, Zhenghua Jiang, Zhaochun Wu

“…Pharmacotherapy is the most common option for the management of alcohol problems; however, it suffers from multiple problems. …”
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Network Project Activities and Digital Tools for their Implementation by A. A. Belolobova

“…The relevance of this work is that the services used in the course of studying the discipline “Informatics and ICT” must constantly change to the most modern ones and demonstrate to students the relevant tools necessary for a modern graduate and specialist. …”
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Assessment of Esophageal High-Resolution Impedance Manometry in Patients with Nonobstructive Dysphagia by Zhaoyu Liu, Jiazhi Liao, Dean Tian, Mei Liu, Zili Dan, Qin Yu

“…Conclusion. Achalasia was the most common esophageal dysmotility in NOD patients, followed by nonspecific esophageal motility disorders. …”
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Analysis on Composition and Sensory Quality of Characteristic Flavor Substances in Different Cold-eating Rabbits by Ke DONG, Hongnan YUE, Xinyue ZHANG, Zhifeng ZHAO, Wenhao XIA, Dake XIONG, Zuojun WANG, Teng XU

“…Linalool was identified as the most abundant compound in these samples, with relative contents ranging from 15.63% to 57.89%, followed by 4-terpineol, which had a relative content between 0.92% and 1.65%. …”
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First Annoted Checklist of Aquatic Diptera (Insecta) of Two Ramsar Sites (Ahançal and Aït Bouguemaz Rivers) at the Central High Atlas (Morocco): Families Ceratopogonidae, Chironomi... by El-Mostafa Benka, Mohamed Dakki, Abdessamad Ouibimah, Mohamed Mounir, Ikram Douini, Kawtar Kettani, Oumnia Himmi, Soumaya Hammada

“…The two rivers have similar richness (21 taxa each), mainly due to Chironomidae (94%), the most abundant and diversified family. The Empididae (4.8%) are relatively under-represented in the two rivers, as well as the other families (Ceratopogonidae, Tipulidae, and Tabanidae), which do not exceed 1% of the total dipteran abundance. …”
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Analysis of Inpatient Mortality Cases in a Tertiary General Hospital in Beijing Based on Diagnosis-related Groups by ZHANG Yufei, ZHOU Jiong, MA Xiaojun, WANG Xiaoran

“…Low/medium-low-risk mortality cases predominantly originated from the Medical Intensive Care Unit (MICU) and ICU (37.8%, 128/339). The most frequent DRG group among all mortality cases was RW29, while EC13 (Tuberculosis, Operating Room Procedure with Complications/Comorbidities) accounted for the majority of low/medium-low-risk deaths. …”
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Development experience of information system for ranking of academic and pedagogical staff by A. A. Chernousov, E. V. Vavilova

“…According to the authors, the most appropriate method of assessing the diverse activities of the Faculty members is a technique based on the method of qualimetry – ranking objects in ascending or descending order based on the calculation of a certain set of features. …”
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Effects of Metformin on Survival and Toxicity in Patients with Metastatic Non-Small Cell Lung Cancer Treated with Nivolumab by Heves Surmeli, Sedat Yildirim, Deniz Isik, Oguzcan Kinikoglu, Yunus Emre Altintas, Ugur Ozkerim, Sıla Oksuz

“…Overall survival was significantly longer in the metformin group (5.02 ± 3.93 vs. 4.6 ± 3.79 years, <i>p</i> < 0.05), while progression-free survival did not differ significantly (1.32 ± 0.97 vs. 1.04 ± 0.75 years, <i>p</i> = 0.385). Although most adverse events were similar across groups, grade 3–4 thrombocytopenia was more frequent in metformin users (<i>p</i> < 0.05). …”
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Enhancing confidence and skills in ultrasound-guided IV access: a quality improvement project by Elpis Pola, Muhammad Dawood Sohail, Tariro Chikwanha

“…. • Baseline confidence: most participants were at a beginner–novice level before training. • Survey responses: 23/23 completed pre-training surveys; 19/23 completed post-training surveys. • Key findings: confidence levels improved across all three assessed parameters. • Qualitative feedback: participants valued the hands-on practice, with many expressing increased confidence in applying USG-IV techniques in clinical settings (Fig 1).Clinical relevance and impactImproving USG-IV skills has direct benefits for patient care, including: 1. …”
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The incidence of liver injury in Uyghur patients treated for TB in Xinjiang Uyghur autonomous region, China, and its association with hepatic enzyme polymorphisms nat2, cyp2e1, gst... by Yang Xiang, Long Ma, Weidong Wu, Wei Liu, Yongguang Li, Xia Zhu, Qian Wang, Jinfeng Ma, Mingqin Cao, Qian Wang, Xuemei Yao, Lei Yang, Atikaimu Wubuli, Corinne Merle, Paul Milligan, Ying Mao, Jiayi Gu, Xiumei Xin

“…<h4>Background and objective</h4>Of three first-line anti-tuberculosis (anti-TB) drugs, isoniazid is most commonly associated with hepatotoxicity. Differences in INH-induced toxicity have been attributed to genetic variability at several loci, NAT2, CYP2E1, GSTM1and GSTT1, that code for drug-metabolizing enzymes. …”
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Patient safety education in undergraduate medical education through a global lens: a scoping review by Njoud Aldardeir, Qabirul Karan Abdullah, Linda Jones

“…Four themes were identified, cultural and contextual considerations; curriculum structure/session design; student engagement/ application; leadership support and faculty training. Conclusions Most publications and discourses emerged from WEIRD countries. …”
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Diagnostic test accuracy for detecting Schistosoma japonicum and S. mekongi in humans: A systematic review and meta-analysis. by Md Obaidur Rahman, Miho Sassa, Natasha Parvin, Md Rashedul Islam, Aya Yajima, Erika Ota

“…<h4>Background</h4>Most of national schistosomiasis elimination programmes in Asia are relying on stool examination, particularly Kato Katz stool examination technique for regular transmission monitoring. …”
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Nutritional profiling and sensory evaluation of hilsa Tenualosa Ilisha (Hamilton, 1822) eggs roe from three different locations of Bangladesh by Muhammad Anamul Kabir, Kamrul Islam, Shishir Kumar Nandi, Sanzida Hoque, El-Sayed Hemdan Eissa, Hien Van Doan, Suniza Anis Mohamad Sukri, Zulhisyam Abdul Kari

“…Significant (P < 0.05) variations were found in most of the amino acid contents in Hilsa eggs from distinct locations. …”
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Avalanche hazard and control in Kazakhstan by V. P. Blagoveshchensky, I. E. Gulyaeva, O. A. Berman, V. V. Zhdanov, M. E. Tatkova

“…Protective constructions are built very rarely. The most large-scale project is the protection of the Medeo skating-rink in Il’ Alatau where in 1974 special snow-retentive boards of wooden beams on metal supports were constructed on the above located slope. …”
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Predicting cadmium enrichment in crops/vegetables and identifying the effects of soil factors based on transfer learning methods by Rui Chen, Zean Liu, Jingyan Yang, Tiantian Ma, Aihong Guo, Rongguang Shi

“…In the case of good prediction effect of transfer learning, available Cd is the most critical function, and available Cd is positively correlated with Cd in plants. …”
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Nesprin-2 contains BH3-like motifs that can promote cell death by Hila Zohar, Amit Kessel, Liora Lindenboim, Dang Nguyen, Nir Ben-Tal, Gregg G. Gundersen, Howard J. Worman, David W. Andrews, Reuven Stein

“…SYNE2 encodes multiple nesprin-2 (Nes2) isoforms of which the most abundant and the largest is the nuclear envelope protein nesprin-2 giant (Nes2G). …”
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COVID-19 safe dental practices among a group of Egyptian students: a cross-sectional study by Dena Ali Abozaid, Dina Hamed, Karim Mostafa Hindy, Mayar Moustafa Budair, Ziad Baher Hussein, Ziyad Islam Hegazy, Dina Nabih Kamel Boulos

“…Practice of hand hygiene was the most common safe dental practice among the students, and they practiced it all the time (82.7%), whereas checking patient temperature was the least common practice (28.8%). …”
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Prenatal diagnosis and molecular cytogenetic characterization of 12 cases of chromosome 8 inverted duplication deletion syndrome by Xi Yang, Rong Hu, Weiwei Huang, Jian Lu

“…Conclusion The intrauterine phenotypes of inv dup del (8p) are diverse, with cerebral and cardiac anomalies being the most commonly observed ultrasound findings. However, these clinical manifestations are not specific to inv dup del (8p), and some fetuses may not exhibit noticeable ultrasound abnormalities during early gestation. …”
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KESULITAN SISWA DALAM MENYELESAIKAN SOAL CERITA ALJABAR by Marfi Ario, Suhendra Suhendra

“…Algebra is an essential component of mathematics education, supporting a deeper understanding of advanced mathematical concepts and having broad applications across various disciplines. One of the most significant challenges students encounter in algebra learning is solving word problems. …”
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Continuity of Visiting Pharmacist Services and Factors Related to Service Discontinuation Among Older Adults in Japan: A Retrospective Cohort Study by Reina Taguchi, Akira Okada, Rumiko Tsuchiya‐Ito, Satomi Kitamura, Tomoki Ishikawa, Shota Hamada

“…The median time to any‐cause cessation was 11 and 2 months for all participants and those with terminal cancer, respectively. Death was the most common reason for cessation, with a 12‐month cumulative incidence of 0.25 (95% confidence interval: 0.24–0.27). …”
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