Inflammatory response of cultured macrophages in treatment-naive patients with systemic sclerosis by E. V. Gerasimova, A. I. Bogatyreva, T. V. Kirichenko, T. V. Popkova, R. U. Shayakhmetova, L. P. Ananyeva, Yu. V. Markina, A. M. Markin, A. N. Orekhov

“…Macrophages activated via a proinflammatory pathway can be considered as major participants in the maintaining of system chronic lowgrade inflammation.The aim of this study was to evaluate the inflammatory response and of macrophages in patients with systemic sclerosis to reveal the most significant inflammatory mediators in pathogenesis of this disease.Materials and methods. …”
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An evaluation of menstrual health apps’ functionality, inclusiveness, and health education information by Emma Bucher, Callie Sharkey, Abby Henderson, Briette Basaran, Sarah Meyer, Chen X. Chen

“…Results For functionality, half of the apps had third-party advertisements. Most (71.4%) did not require cellular connection to utilize menstrual symptom-tracking, and 71.4% shared user data with third parties. …”
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Nuclear medicine in prostate cancer: A new era for radiotracers by Vincenzo Cuccurullo, Giuseppe Di Stasio, Luigi Mansi

“…Several PSMA-targeted PET tracers have been developed many of which showing promising results for accurate diagnosis and staging of primary PCa and re-staging after biochemical recurrence, even in case of low prostate specific antigen values. In particular, the most widely used PSMA ligand for PET imaging is a 68Ga-labelled PSMA inhibitor, 68Ga-PSMA-HBED-CC (68Ga-PSMA-11). 99mTc-HYNIC-Glu-Urea-A for single photon emission computed tomography, and 177Lu-PSMA-617 for radioligand therapy has also been applied in humans, with interesting preliminary results related to a possible theranostic approach. …”
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Bridge-Enhanced ACL Repair: Novel approach and emerging opportunities in anterior cruciate ligament injury management - literature review by Adam Krzaczkowski, Oliwia Barańska, Małgorzata Chańko, Justyna Drożdżał, Emilia Niedzieska, Magdalena Rędaszka, Joanna Szuba, Zofia Szular, Tymon Wojczulis, Katarzyna Ziemek

“… Anterior cruciate ligament injury is one of the most common trauma in sport. It leads to long-term exclusion from physical activity, poor quality of life and may result in posttraumatic osteoarthritis. …”
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Plasma homocysteine levels and associated factors in community-dwelling adolescents: the EVA-TYROL study by Nina Gande, Christoph Hochmayr, Anna Staudt, Benoît Bernar, Katharina Stock, Sophia Zollner-Kiechl, Ralf Geiger, Ralf Geiger, Andrea Griesmacher, Sabine Scholl-Bürgi, Michael Knoflach, Raimund Pechlaner, Ursula Kiechl-Kohlendorfer, the (Early Vascular Ageing) EVA Study Group, the (Early Vascular Ageing) EVA Study Group

“…Univariate associations with Hcy emerged for age, sex, body mass index, high-density lipoprotein cholesterol, and for factors pertaining to blood pressure, glucose metabolism, renal function, and diet quality, whereas the most important multivariate predictors of Hcy were sex and creatinine.DiscussionClinical and laboratory factors associated with Hcy in adolescents were manifold, with sex and high creatinine identified as strongest independent determinants. …”
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Dry eye masky syndrome: degree of expression and possibilities of correction by S. I. Makogon, N. V. Gorbacheva, D. I. Ivanova, Yu. S. Khlopkova

“…At this stage of the study, 2 questionnaires were used to assess the severity of DES symptoms: OSDI and DEQ, Schirmer I test.   Results. Most of the study participants noted the constant wearing of masks (86.4 % of doctors and 84.8 % of nurses). …”
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The influence of age, sex, and mandibular morphometric parameters on cortical bone width and erosion: a panoramic radiography study by Bramma Kiswanjaya, Shafira Ramadhanti Taufiq, Syurri Innaddinna Syahraini, Akihiro Yoshihara

“…Statistical analysis included Spearman's correlation, multiple regression, and logistic regression to assess the relationships between mandibular morphology, cortical width, and cortical erosion with age and sex.ResultsSignificant differences were observed across age and sex groups in most mandibular parameters. Men had significantly larger values for ramus height, bigonial width, and condylar height, while women showed a wider gonial angle. …”
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IoT and ML-driven framework for managing infectious disease risks in communal spaces: a post-COVID perspective by Dhruv Parikh, Avaneesh Karthikeyan, V. Ravi, Merin Shibu, Riya Singh, Reka S. Sofana

“…COVID-19 has not only changed the way people live but has also altered the way all organizations operate. The most effective precautionary measure against the spread of the virus that caused the COVID-19 pandemic SARS-CoV-2, is to use face coverings in public settings. …”
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Wet Aging USDA Select Beef Strip Steaks: Implications on Consumer Acceptability, Demand, and Product Selection by Anuraj Sukumaran, Caleb Lemley, Chelsie Dahlgren, Derris Burnett, Kalyn B Coatney, Kezia To, Shangshang Wang, Thu Dinh, Wes Schilling, Xue Zhang

“…Under optimal pricing and various cost scenarios, 21 d of aging was the most profitable single product offering only if daily production costs were sufficiently low.…”
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Preparation of Nitrogen-Rich Tar by Co-Pyrolysis and Analysis of Nitrogen-Containing Compounds in Pyrolysis Products by Peiqi Chen, Gang Li, Jie Shao, Baoping Bai, Jie Hu, Xiang Han, Anning Zhou, Qiuhong Wang, Fuxin Chen

“…It was found that the five-membered nitrogen heterocycles were the most abundant, accounting for 34.88%. In addition, five other nitrogen-containing compounds containing different functional groups and the tar from the co-pyrolysis of tar-rich coal were also analyzed by GC/MS, among which the tar from melamine had the highest content of nitrogen-containing compounds, with 70.48%. …”
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EEG FREQUENCIES PATTERN AS BRAIN SIGNATURE OF EMOTIONAL BURNOUT. ANXIETY TENSION STAGE FORMATION by Semen A. Mushta, Svitlana P. Palamar, Dmytro V. Harmatiuk, Anton O. Popov, Joao M. Alves Ferreira, Mykola Yu. Makarchuk, Sergii V. Tukaiev

“…The prospect of increasing annually makes burnout a global phenomenon, one of the most common stress-related and mental disorders. …”
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Hemostasis features in pregnant women with hypertensive disorders living in the highlands of Tadzhikistan Republic by N. A. Tadzhiboeva, A. G. Yashchuk, I. B. Fatkullina, S. A. Galeeva, A. Yu. Lazareva, N. A. Stetsenko, D. G. Sitdikova

“…Pregnant women living in highlands are exposed to adverse factors, the most important of which is decreased oxygen in the air. …”
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Integration of scRNA-Seq and Bulk RNA-Seq Identifies Circadian Rhythm Disruption-Related Genes Associated with Prognosis and Drug Resistance in Colorectal Cancer Patients by Tao Y, Li J, Pan J, Wang Q, Ke RW, Yuan D, Wu H, Cao Y, Zhao L

“…Yong Tao,1,* Jun Li,1 Jianhui Pan,1 Qing Wang,1 Ru Wei Ke,1 Danping Yuan,1 Hongbiao Wu,1 Yuepeng Cao,1 Lei Zhao2,* 1Department of Colorectal Surgery, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, People’s Republic of China; 2Department of Anorectal Surgery, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People’s Hospital, Quzhou, Zhejiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lei Zhao, Email fyytaoyong@nbu.edu.cn Yuepeng Cao, Email doctorcaoyp@126.comBackground: Colorectal cancer (CRC) is one of the most prevalent malignancies worldwide. With the increasing incidence of CRC, there is an urgent need for effective strategies for early diagnosis and treatment. …”
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NRF2 polymorphism and susceptibility to ischemic stroke in a Chinese population by Pengyu Wang, Junxiu Lu, Min Wang, Guangming Wang, Huaqiu Chen

“…The CCTTGGC haplotype was the most common in both groups. Stratified analysis of rs35652124 showed no association with confounding factors such as age, sex, hypertension, diabetes, or lipid levels. …”
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Day case total laparoscopic hysterectomy in a low resource setting: A descriptive analysis by Vishal Bahall, Keevan Singh, Lance De Barry

“…The perioperative management protocol was also outlined. Results: The most common indication for TLH was uterine leiomyoma (45%), followed by endometrial cancer (17.5%). …”
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Human Epidermal Growth Factor Receptor 2-Low Breast Cancer: Prevalence Rate and Scoring Concordance Among Pathologists by Maher Sughayer, Ghada Al-Jussani, Ahmed Salem, Yassin Mullahwaish, Fanar Alsmarat, Dua Abuquteish

“…Consensus scoring showed 1+ as the most frequent HER2 score. Complete agreement among all 3 pathologists occurred in 78 tumors (67.2%), while high agreement (agreement among 2 pathologists) occurred in 38 tumors (32.8%). …”
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RISK FACTOR PREVALENCE AND PROBABILITY OF FATAL CARDIOVASCULAR EVENTS IN MEN 42-44 YEARS OLD by A. A. Aleksandrov, V. B. Rozanov, Е. Yu. Zvolinskaya, Kh. S. Pugoeva

“…At the moment of study, 23% of men had elevated blood pressure, mostly at the level of arterial hypertension (AH) grade 1 (14,5%). …”
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First Principles Calculation Guided Material Selection of Poly(propylenemonothiocarbonate) for High-Performance Triboelectric Nanogenerators by Muhammad Naeem Shah, Jiaqi Lu, Dinku Hazarika, Munir Ullah Khan, Srinivasa Rao Pathipati, Kaihang Zhang, Liangquan Xu, Jie Li, Xiaozhi Wang, Shurong Dong, Jikui Luo

“…The advancement of the information era has raised growing interest in triboelectric nanogenerators (TENGs) as environmentally friendly micropower sources. However, most developments to increase the power outputs of TENGs have focused on tribo-negative materials, with limited exploration of tribo-positive materials. …”
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Physiological and histological study of the effect of Cumin Cyminum watery extract and vitamin E on the male reproductive system in rats exposed to oxidative stress by Othman Aeed Saleh Alfahdawi, Muneef Saab Ahmed Aljanabi, Treefa Farouq Ismail

“…The water extract of Cumin plant acts as an antioxidant through its important role in curbing the harmful effects of some types of free radicals within the body and thus repair the damage in most of the physiological and histological changes and functions of the male reproductive system of rats with exposure to oxidative. …”
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Cholecystectomy-related gut microbiota dysbiosis exacerbates colorectal tumorigenesis by Bo Tang, Shengpeng Li, Xin Li, Jialin He, An Zhou, Lingyi Wu, Xu Xiao, Sumin Wang, Hongfei Jiang, Jincheng Jian, Zhanjie Hou, Yusong Ge, Yuanyuan Lei, Jianchun Zhou, Dianji Tu, Cheng Lu, Min Yang, Shiming Yang

“…Abstract Cholecystectomy represents the most prevalent biliary surgical procedure for gallbladder abnormalities. …”
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