RNA-Seq Analysis Revealed the Virulence Regulatory Network Mediated by the Ferric Uptake Regulator (Fur) in <i>Apostichopus japonicus</i> Pathogenesis Induced by <i>Vibrio splendid... by Changyu Liao, Lincheng Hu, Si Zhu, Weikang Liang, Lei Yang, Chenghua Li

“…Comparative analysis between wild-type and <i>Vsfur</i> knockdown strains shows that <i>Vsfur</i> knockdown altered the expression of 3593 genes in <i>V. splendidus</i>, with the most significant differential expression observed under simulated pathogenic conditions (1030 upregulated and 72 downregulated). …”
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Modeling mesenchymal stromal cell support to hematopoiesis within a novel 3D artificial marrow organoid system by Bérénice Schell, Lin-Pierre Zhao, Inés M’Sibih, Maria Kalogeraki, Camille Kergaravat, Emilie Lereclus, Pierre Fenaux, Lionel Adès, Antoine Toubert, Marion Espéli, Karl Balabanian, Emmanuel Clave, Nicolas Dulphy, Valeria Bisio

“…This fully-human Artificial Marrow Organoid (AMO) model is highly efficient to recapitulate MSC support to myeloid differentiation and NK cell development from the immature CD34 + HSPCs to the most terminally differentiated CD15 + polymorphonuclear neutrophils, CD64 + monocytes or NKG2A-KIR2D + CD57 + NK subset. …”
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Photothermally Driven Ultrafast Polymerase Chain Reaction: Mechanisms, Nanomaterial Architectures, and System Integration by Yile Fang, Lijun Cai, Ning Li, Feika Bian, Dagan Zhang, Nongyue He, Zhiyang Li, Hong Yan, Yuanjin Zhao

“…As one of the most important technologies in molecular biology, polymerase chain reaction (PCR) has been widely recognized in many fields such as infectious disease diagnosis due to its high sensitivity, specificity, and accuracy. …”
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Investigating the Effects of Sleep Health Education Based on Mobile Application on Sleep Quality of the Elderly: A Quasi-Experimental Study by Shahla Asiri, Hananeh Rahimi, Ehsan Kazemnezhad Leyli, Negar Pourvakhshoori

“…Objectives Sleep disorders are among the most prevalent issues impacting the quality of the elderly. …”
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Resumen del II Congreso Latinoamericano de Estudiantes de Ingeniería Mecánica y Metalurgia. // Summary of the 2nd Latin-American Congress for Students of Mechanical Engineering. by D. William Fonseca, G. González Rey

“…After an arduous work and many good successes is presented a report on the most<br />important results and summarizes the main activities carried out during this Congress.…”
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Evaluating Large Cardamom Agriculture Practices: A Case Study from Panchthar, Nepal by Sarina Basnet, Anup Bhatt, Saugat Gautam, Sajan Danji, Sujan Amgai

“…The study revealed that 28% of farmers grew the Ramsai cultivar, with over 82% having access to irrigation. Most farmers (77%) managed shade well and maintained their orchards effectively. …”
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Evaluating preceptorship during advanced pharmacy practice experiences in Saudi Arabia: A Cross-Sectional Study by Faris S. Alnezary, Fahad Alzahrani, Yasser Alatawi, Abdullah A. Alhifany

“…Almost 50% of the preceptors exhibited competence in pharmacotherapy-related science, demonstrated a willingness to teach students and acknowledged the students’ knowledge and skills. Furthermore, most of the students reported understanding of the APPEs objectives as the internship progressed. …”
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Exploring the Impact of Stroke on Lower Limb Proprioception: Insights into Physiotherapy Interventions for Rehabilitation: Systematic Review by Trishna Saikia Baruah, Pratap Chandra Sarma

“…The studies varied in design, with most being randomized controlled trials. Interventions included sensory re-education, balance training, and proprioceptive exercises targeting the lower limbs. …”
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Phenotypic stasis with genetic divergence by Mallard, François, Noble, Luke, Guzella, Thiago, Afonso, Bruno, Baer, Charles F., Teotónio, Henrique

“…In contrast, transition rates’ genetic (co)variance structure showed a marked divergence from the ancestral state and differentiation among replicate populations during the final 100 generations and after most adaptation had been achieved. We observe that genetic differentiation is a transient pattern during the loss of genetic variance along phenotypic dimensions under drift during the last 100 generations of lab evolution. …”
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Costs and consumption of analgesics, with special reference to opiates in Serbia and Montenegro from 2015 to 2019 by Mladenović Katarina, Dragojević-Simić Viktorija, Mugoša Snežana, Rančić Nemanja

“…Over the course of five years (from 2015 to 2019) in Serbia, the total allocations for analgesic therapy had a rising trend, from about 43.6 million to 63.3 million euros, while in Montenegro, expenditures showed annual variations with the highest value in 2018. Most of the money in both countries was invested in the M01A group of drugs, for which the highest consumption was also recorded. …”
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The effect of osteopathic manipulative treatment on lenght of stay and pain relief in pediatric appendectomy: a pilot non-randomized time-controlled clinical trial by Roberto Lo Piccolo, Roberto Lo Piccolo, Michele Maria Cantagalli, Tommaso Ferroni, Florinda Fracchiolla, Antonino Morabito, Antonino Morabito

“…IntroductionAppendicitis is the most frequent non-traumatic surgical emergency in children. …”
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Green Synthesis of Silver Nanoparticles Using Aqueous Extract of Typha domingensis Pers. Pollen (qurraid) and Evaluate its Antibacterial Activity by Ali Aboud Shareef, Fadhil Jabbar Farhan, Fulla A. Alsatter Alriyahee

“…The ability of the AgNPs was tested against four bacterial species, three of which were Gram-negative Escherichia coli A1, Escherichia coli A2, Alcaligenes faecalis AL1,  and the fourth was Gram-positive bacteria Bacillus zanthoxyli B1 , which were identified by traditional and molecular methods using 16SrRNA gene sequencing, antibacterial activity results of AgNPs  showed that it increases with increasing of  AgNPs concentration, and the most sensitive species to silver particles was  Alcaligenes faecalis AL1bacteria. …”
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Clinical features of heart failure in patients with atrial fibrillation: the role of the endovascular left atrial appendage closure by D. V. Pevzner, N. S. Kostritca, I. A. Merkulova, O. B. Dorogun, A. L. Komarov, I. S. Yavelov

“…The study included 139 patients (55 — LAAO group; 84 — control group) with a 3-year follow-up period. Most patients in the study had class I-III HF with preserved left ventricular ejection fraction (93,5%). …”
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Open Education System in Management Training in the Digital Economy by L. P. Gancharik

“…It becomes effective if its principles and technologies are implemented at all levels of government and depends largely on the competences in this area of the administrative apparatus, both at the federal and regional levels.The open education system is based on large-scale distance learning technologies, at the same time covering a huge contingent of students, and is aimed at student-centered learning and competence-basedapproach. Therefore, it is the most effective methodology for training, on the one hand related to synergetic approaches and models, and on the other, it can become the national basis for the formation of managerial competencies of the administrative apparatus, both federal and regional levels in the field of digital transformation.In recent years, European countries have been actively developing national qualifications systems (NQFs), based on a unified qualifications system (ESC), aimed at streamlining the existing diversity of education and training. …”
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Antimicrobial susceptibility profiles of commensal Clostridium perfringens isolates from chickens in Hungarian poultry farms between 2022 and 2023 by Ádám Kerek, Ádám Kerek, Ábel Szabó, Franciska Barnácz, Bence Csirmaz, László Kovács, László Kovács, László Kovács, Ákos Jerzsele, Ákos Jerzsele

“…IntroductionOne of the most pressing challenges of our time is the global spread of antimicrobial resistance (AMR). …”
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Analysis of patient medical exposure in X-ray diagnostics in Russia for half a century (1970–2019) by S. A. Kalnitsky, N. V. Tselikov

“…The reader is offered a complex radiation-hygienic analysis of the 50-year medical exposure of patients and of the population in Russia to inform and analyze the available data on the most common type of use of ionizing radiation sources in the national economy. …”
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A qualitative study of a new metric for estimating early-onset colorectal cancer risk in male veterans: “Colon Age” by Thomas F. Imperiale, Michael Cheng, Melissa R. Thomas, Marianne S. Matthias

“…Patients (mean age 47 years, 100% male) expressed willingness to follow screening recommendations from their provider, although most were unaware of other screening options beyond colonoscopy. …”
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COVID-19 Vaccine Timing and Co-Administration with Influenza Vaccines in Canada: A Systematic Review with Comparative Insights from G7 Countries by Farah Al hashimi, Sherif Eneye Shuaib, Nicola Luigi Bragazzi, Shengyuan Chen, Jianhong Wu

“…Results: Evidence summarized across G7 countries reveals that most nations are converging on annual or flexible booster schedules tailored to high-risk groups, often aligning COVID-19 vaccination with influenza campaigns. …”
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Comprehensive Evaluation of Starch and Noodles Quality of Different Sweet Potato Varieties Based on Principal Component Analysis and Cluster Analysis by Mi LUO, Wang YIN, Renju DENG, Yufang GUAN, Mu PAN, Qiaoyu WU, Mei FU

“…By principal component analysis, 28 quality indicators were simplified into 7 principal components, and the cumulative variance contribution rate was 96.761%, which could reflect most of the information of the original indicators. …”
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Thoracoscopic Cystostomy of Pulmonary Hydatid Cyst in Children by Ufuk Ateș, Ergun Ergün, Gülnur Göllü, Aydın Yağmurlu, A. Murat Çakmak, Hüseyin Dindar, Meltem Bingöl-Koloğlu

“…In humans, the lungs are the second most commonly affected sites. The disease may affect children and its treatment may be challenging. …”
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