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79661
A dynamic model of interactions of Ca2+, calmodulin, and catalytic subunits of Ca2+/calmodulin-dependent protein kinase II.
Published 2010-02-01“…We used parameter sensitivity analysis to identify which parameters will be most beneficial to measure more carefully to improve the accuracy of predictions. …”
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79662
Assessing Local Distribution of Alien Ponto-Caspian Mysids in Lithuanian Waters, the Baltic Sea Basin: Do Sampling Method and Time Matter?
Published 2025-04-01“…Here, we present data from the most recent comprehensive survey of Ponto Caspian mysids and analyze the impact of sampling method on the likelihood of species detection. …”
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79663
Automated Traumatic Bleeding Detection in Whole-Body CT Using 3D Object Detection Model
Published 2025-07-01“…Traumatic injury remains a major cause of death worldwide, with bleeding being one of its most critical and life-threatening consequences. …”
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79664
Impact of the COVID-19 pandemic on admissions of deceased to an institute of legal medicine in Germany
Published 2025-04-01“…In addition, the pandemic’s impact on one of the structurally most important public health determinants, poverty, on numbers of admissions in different place of death categories was analyzed. …”
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79665
Oxamniquine derivatives overcome Praziquantel treatment limitations for Schistosomiasis.
Published 2023-07-01“…To understand how OXA derivatives fit in the SULT binding pocket, X-ray crystal structures of CIDD-0150303 and CIDD-0150610 demonstrate that the SULT active site will accommodate further modifications to our most active compounds as we fine tune them to increase favorable pharmacokinetic properties. …”
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79666
Understanding epistatic networks in the B1 β-lactamases through coevolutionary statistical modeling and deep mutational scanning
Published 2024-09-01“…Abstract Throughout evolution, protein families undergo substantial sequence divergence while preserving structure and function. Although most mutations are deleterious, evolution can explore sequence space via epistatic networks of intramolecular interactions that alleviate the harmful mutations. …”
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79667
Distribution of nutrients and chlorophyll across an equatorial reef region: Insights on coastal gradients
Published 2022-11-01“…Moreover, dissolved reactive silicon (DSi) was low in most samples (< 2.0 µM), but higher (>10 µM) in nearshore stations, probably related to continental runoff and/or resuspension of the bottom sediments. …”
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79668
Specific binding of human P[28] rotavirus VP8* protein to blood group ABH antigens on type 1 chains.
Published 2025-07-01“…In the present study, using a multiphasic approach, including X-ray crystallography, glycan microarray with a dedicated probe library, bio-layer interferometry, site-specific mutagenesis, and molecular docking and dynamics simulations, we found that P[28]-VP8* can bind to all blood group A, B and H(O) antigens but on type 1 chain only, without the capability to bind to any Lewis epitopes or mucin O-glycan cores. Different from most of the prevalent human RVs, such as P[8], P[4] and P[6], the broad HBGA binding specificity of P[28]-VP8* and the fact of the recently identified a possible reassortment P[28] strain of bat and human RVs have raised the concern of a future possibility of P[I] genogroup RV epidemic. …”
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79669
Host Immune Response to Clinical Hypervirulent Klebsiella pneumoniae Pulmonary Infections via Transcriptome Analysis
Published 2022-01-01“…Results of ICEPOP showed neutrophils functions as the most essential cell type against K. pneumoniae infection. …”
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79670
Exercise for Individuals with Lewy Body Dementia: A Systematic Review.
Published 2016-01-01“…Other outcomes appeared to improve modestly in most participants.<h4>Discussion</h4>Scarce research investigating exercise in LBD exists. …”
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79671
Formulation, Process Optimization, and Biochemical Characterization of Cereal-Based Sweet Potato and Mulberry Instant Beverage
Published 2024-01-01“…Most of the beverages have a high glycemic index, which is attributed to a sudden rise in blood sugar. …”
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79672
Development of a milk-containing drink fermented with chickpea extract
Published 2024-10-01“…According to the research results, composition No. 1 made it possible to obtain a milk-containing drink fermented with chickpea extract, which was the most acceptable in terms of organoleptic indicators.…”
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79673
The Urban Draw of Pistoia: from historical cartography to metric design
Published 2019-06-01“…In order to find an answer to the foundation of the hypothesis of a well defined design it was therefore necessary to place oneself on a different level from the usual one and observe the city from above. We know that most of the churches and convents that arose in these periods were born by the will of mendicant religious orders that increasingly spread thanks to the work and preaching of their founding friars who became saints shortly after their death (San Francesco, San Domenico, Sant ‘Agostino). …”
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79674
Induction of wheat resistance by Streptomyces sp. HU2014 strain
Published 2023-04-01“…That is, changes in the activity of all three enzymes were mostly determined by the strain of Streptomyces sp. …”
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79675
Nonadherence to Medication Therapy in Haemodialysis Patients: A Systematic Review.
Published 2015-01-01“…The prevalence of medication nonadherence varied from 12.5% to 98.6%, with widespread heterogeneity in measures and definitions employed. Most common patient-related factors significantly associated with nonadherence were younger age, non-Caucasian ethnicity, illness interfering family life, being a smoker, and living single and being divorced or widowed. …”
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79676
Solar FaultNet: Advanced Fault Detection and Classification in Solar PV Systems Using SwinProba‐GeNet and BaBa Optimizer Models
Published 2025-07-01“…It directly affects the development of sustainable development goals (SDGs), especially those on affordable and clean energy and climate action. However, most of the existing research studies related to fault detection methods have suffered from low accuracy, higher error rates, and time‐consuming processes when dealing with complex fault types in real‐time. …”
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79677
Enrichment strategy and initial characterization of heterodimers enriched from a co-formulated cocktail of therapeutic antibodies against SARS-COV-2
Published 2024-12-01“…Therefore, it is critical to develop methods to evaluate the risk of heteromers as an impurity that could affect potency, efficacy, and/or immunogenicity. The most direct strategy to evaluate antibody heteromers is via specific enrichment. …”
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79678
Development in Rubber Preparation for Endoscopic Training Simulator
Published 2016-01-01“…Endoscopy is one of the most important procedures in diagnosis and treatment of gastrointestinal tract problems. …”
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79679
Comparative Study of the Immune Response Induced by an Argentinian Classical Strain of IBDV in Two Chicken Breeds
Published 2022-01-01“…Infectious bursal disease virus (IBDV) causes a highly contagious viral disease that affects the bursa of Fabricius. Although most chickens are regularly vaccinated against IBDV, this virus still generates negative impacts on production with significant economic losses. …”
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79680
Green transportation – Environmental sustainability within the purview of green energy, green innovation, and institutional quality: New evidence from belt and road initiatives eco...
Published 2025-06-01“…To shed light on this outcome, we propose a development-matching theory. Most importantly, the study's findings do not suggest a negative influence of green transportation on environmental quality. …”
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