Survival and deterioration time of walking abilities in dogs homozygous for the SOD1 gene mutation with and without thoracolumbar intervertebral disc protrusion by Péter Sebestyén, Malwina Ewa Kowalska, Malwina Ewa Kowalska, Lorenzo Golini

“…Data were analyzed using descriptive statistics and survival analysis.ResultsA total of 39 dogs were enrolled in the study, with a mean age of 115 months and a mean weight of 29 kg at the time of diagnosis. The most common breed was the German Shepherd (n = 9/39). …”
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Navigating challenges in human pluripotent stem cell-derived islet therapy for type 1 diabetes by Mohammed Usama, Mohammed Usama, Ying Deng, Ying Deng, Yiran Chen, Théa Milland, Théa Milland, Mohan Malleshaiah, Mohan Malleshaiah, Mohan Malleshaiah, Yasaman Aghazadeh, Yasaman Aghazadeh, Yasaman Aghazadeh

“…The results and challenges of these trials inspired new areas of research, leading to incremental advances in cell differentiation and delivery technologies, and a deeper understanding of the transplantation microenvironment to enhance therapeutic efficacy and longevity. Reports from the most recent trials demonstrated success in reducing or eliminating exogenous insulin administration for people with T1D, increasing hope for a cure for T1D via regenerative medicine. …”
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Treatment of indolent systemic mastocytosis with sarilumab is not supported in a randomized trial by Hirsh D. Komarow, MD, Jing Wang, MS, Robin Eisch, RN, Linda Scott, CRNP, Erica H. Brittain, PhD, Dean D. Metcalfe, MD, MS

“…The estimated treatment effect from regression analysis was a 6.0-unit advantage of MC-QoL in the placebo arm (P = .40; 95% confidence interval, −8.9, 20.8), limiting a possible sarilumab advantage to at most 9 units of MC-QoL. Similar conclusions were observed for other quality-of-life indices. …”
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Prediction of the nutritional values by INRA (2018) feed evaluation system of Megathyrsus maximus subjected to different grazing strategies by Santiago Alexander Guamán Rivera, Angela Edith Guerrero-Pincay, Nelson Rene Ortiz-Naveda, Raúl Lorenzo González-Marcillo

“…Several studies have showed that the accuracy and precision of the feeding values are critical to achieve this goal, unfortunately, in Ecuador there are not referential data, despite of Megathyrsus maximus is the most forage used by livestock farmers. The predominant aim of the current study was to approach and estimate the feeding values by INRA feed evaluation system of Tanzania grass (Megathyrsus maximus) subjected at different grazing strategies. …”
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Mutations of short tandem repeats explain abundant trait heritability in Arabidopsis by Zhi-Qin Zhang, Juan Jiang, Yong-Chao Xu, Craig Dent, Sridevi Sureshkumar, Sureshkumar Balasubramanian, Ya-Long Guo

“…Interspecific comparison between A. thaliana and Arabidopsis lyrata reveals rapid STR turnover, with the most majority of the loci occurring only in A. thaliana. …”
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Optimizing Stimulus Frequency Ranges for Building a High-Rate High Frequency SSVEP-BCI by Xiaogang Chen, Bingchuan Liu, Yijun Wang, Hongyan Cui, Jianwei Dong, Ruijuan Ma, Ning Li, Xiaorong Gao

“…The visual stimuli in the low- and medium-frequency ranges are adopted in most of the existing studies for eliciting SSVEPs. …”
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One-pot, uracil-DNA-glycosylase-aided, and multi-indicator nanobiosensor detection platform for identifying Brucella melitensis from the Brucella spp by Xinggui Yang, Yue Wang, Sha Mao, Ying Liu, Fengming Chen, Junfei Huang, Xiaoyan Zeng, Hai Jiang, Shijun Li

“…., is primarily associated with species such as Brucella melitensis (B. melitensis) and B. abortus, among which B. melitensis is recognized as the most virulent in causing human brucellosis. Methods Herein, we report a newly “one-pot” detection protocol for the identification of B. melitensis from the genus Brucella using the multiplex multiple cross-displacement amplification (MCDA) combined with dUTP-assisted uracil-DNA-glycosylase (UDGase) and gold nanoparticles lateral flow assay (AuNPs-LFA) biosensor (termed mMCUDA). …”
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Biochemical and transcriptomic profiling analysis of drought tolerant related genes in ML 82-2 and ML 125-2 rice mutant lines by Jun Ying Low, Rhun Yian Koh, Sobri Hussein, Ahmad Faiz, Anna Pick Kiong Ling

“…The identified genes in both mutant lines are associated with drought resistance, with most sharing a similar genomic profile with MR220. …”
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Using New York City’s Geographic Data in an Innovative Application of Generative Adversarial Networks (GANs) to Produce Cooling Comparisons of Urban Design by Yuanyuan Li, Lina Zhao, Hao Zheng, Xiaozhou Yang

“…This study employs a combination of qualitative and quantitative metrics to evaluate the performance of different model stages, selecting the most accurate model as the final experimental framework. …”
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The Lattice Structure and Optical Properties of Neodymium-Doped Gadolinium Vanadate Crystals Induced by Ion Irradiation by Mei Qiao, Tiejun Wang, Honglian Song, Jing Zhang, Yong Liu, Peng Liu, Huaijin Zhang, Xuelin Wang

“…In recent times, the neodymium-doped gadolinium vanadate (Nd:GdVO₄) crystal has attracted significant attention as one of the most valuable functional materials, but its lattice structure can be easily modified in an irradiation environment, which determines its related optical properties and affects the performance of devices based on the Nd:GdVO₄ crystal. …”
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Development and Validation of the CHDSI Questionnaire: A New Tool for Measuring Disease-Specific Quality of Life in Children and Adolescents with Congenital Heart Defects by Paul C. Helm, Ulrike M. M. Bauer, Peter Ewert, Julia Remmele

“…<i>Background and Objectives</i>: Congenital heart defects (CHD) affect around 1% of the population, making them the most common congenital disease worldwide. Thanks to advances in treatment, over 90% of affected children are able to reach adulthood, shifting focus to long-term outcomes such as disease-specific quality of life (DsQoL). …”
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Efficacy and safety of tirabrutinib monotherapy in relapsed or refractory B-cell lymphomas/leukemia: a meta-analysis by Jingfei Wang, Hai-en Cheng, Yanhua Sun, Zhenfeng Li, Yunke Zang, Yuying Zhao, Guimao Yang, Zhijun Liu, Yaqi Sun, Yanli Sun

“…The highest median progression-free survival (mPFS) was observed in patients with CLL, reaching 38.5 months. Neutropenia was the most common adverse event (AE), both all grades and grade ≥3. …”
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FACTOR INFLUENCING LENGTH OF STAY OF PATIENTS UNDERGOING BYPASS SURGERY AT SHAHEED MADANEE CARDIAC TEACHING HOSPITAL –TABRIZ — IRAN by Reza Gholi Vahidi, Rahim Khodayari, Shabnam lezadi, Kamal Gholipour

“…Institutional characteristics –physicians practice both in private sector and public teaching hospital, physicians’ level of education, discharge process guidelines, and admission protocols were most important factor in predicting LOS. The patient’s hospitalization history whether patient was hospitalized before or not, was also a predictor.…”
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Physical-mechanical, chemical and biological properties of graphene-reinforced glass ionomer cements by Tatiane Ramos dos Santos Jordão, Laura Soares Viana Fernandes, Karla Lorene de França Leite, Adílis Alexandria, Emmanuel João Nogueira Leal Silva, Lucianne Cople Maia, Tatiana Kelly da Silva Fidalgo

“…A greater fluoride release was observed in the period of 7 days for most of the groups. After 21 days, GKetac 5%, 2%, and 1% presented higher releasing than 0% and 0.5% (p ≤ 0.05).ConclusionsThe graphene incorporation improved the microhardness of GICs in lower concentrations. …”
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Sequence and taxonomic feature evaluation facilitated the discovery of alcohol oxidases by Yilei Han, Xuwei Ding, Junjian Tan, Yajuan Sun, Yunjiang Duan, Zheng Liu, Gaowei Zheng, Diannan Lu

“…Among these selected sequences, 19 were expressed as soluble proteins in E. coli, and 18 of these soluble proteins exhibited AOX activity, as predicted. Notably, the most active recombinant AOX exhibited an activity of 8.65 ± 0.29 U/mg, approaching the highest activity of native eukaryotic enzymes. …”
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Women Participation in Entrepreneurial Activities in the Post COVID-19 Pandemic: Empirical Evidence from SMEs Sector by Sazzad Hossain, Md Shamaun Islam, Susmita Kundu, Omar Faruq, Md. Alomgir Hossen

“…As per study's results, most variables, including administrative, scientific, and familial cooperation, knowledge and skills, psychological, and financial component, has both advantages statistically impressive relationship with women's involvement in the context of the SME area in Bangladesh in the post COVID-19 pandemic. …”
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Optimized Biochar from Chicken Manure via Hydrothermal Activation and Catalytic HTC: Properties and CO₂ Reduction Potential by Seong-Yeun Yoo, Thi. Thu-Trang Ho, Ahmad Nadeem, Seong-Su Kim, Kangil Choe, Jai-Young Lee

“…Among the tested samples, the biochar produced via H₃PO₄ activation and HCl-catalyzed HTC [P-HTC(HCl)] exhibited the most favorable characteristics, including the highest carbon content (59.5 wt.%) and the lowest H/C ratio (0.65). …”
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Forecasting large-scale solar power plant energy production based on Monte Carlo simulations and long-short-term memory by Sheeraz Iqbal, Md Shafiullah, Muhammad Aurangzeb, Irfan Jamil, Abdul Rehman, Asif Islam, Amjad Ali, Salah S. Alharbi

“…The broad-scale development of solar power plants makes the most significant contribution to reducing energy shortages in rural areas. …”
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The predictive value of common symptoms in early pregnancy for complications later in pregnancy and at birth by Ruth Kirk Ertmann, Dagny Ros Nicolaisdottir, Jakob Kragstrup, Gritt Overbeck, Margit Kriegbaum, Volkert Siersma

“…Results Among the 1413 included women, 199 (14%) experienced complications in later pregnancy. The most serious complication, miscarriage, was experienced by 65 women (4.6%). …”
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Examining perinatal regionalization in practice: a network analysis of maternal transport in Georgia by Jingyu Li, Stephanie M. Radke, Lauren N. Steimle

“…Finally, we applied a community-detection algorithm to cluster facilities that were observed to transport among each other most frequently and compared these detected facility clusters to Georgia’s formal DPRs. …”
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