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79401
Neoadjuvant chemotherapy followed by interval debulking surgery versus primary debulking surgery in the advanced epithelial ovarian cancer- a retrospective cohort study
Published 2021-01-01“…In the AOC, the extent of tumor resection (residual tumor volume) is the most important prognostic factor for overall survival (OS) and progression-free survival (PFS). …”
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79402
Assessment of Ecological Recovery Potential of Various Plants in Soil Contaminated by Multiple Metal(loid)s at Various Sites near XiKuangShan Mine
Published 2025-01-01“…Mori absorbed relatively high Sb concentrations in the leaves and roots. (3) After that, we collected rhizosphere soil and tissue samples from eight crops on the above farmland to assess their capacities as recovering vegetation of contaminated farmland soil, of which the fruits of maize accumulated the lowest concentrations of most monitored metal(loid)s (except for Pb). Further, we compared the differences in the bacterial community structure of MF, PF, TM, and TS to assess capacities of cultivating pepper and maize to improve soil microbial community structure. …”
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79403
Video-EEG monitoring in diagnostics and treatment efficacy evaluation in newly-diagnosed generalized epilepsy in adults
Published 2021-04-01“…The first 6 months of initial treatment titration in represent most crucial period for patients with newly-diagnosed IGE.…”
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79404
Time Course of Symptoms in Normal-Pressure Hydrocephalus: A Systematic Review
Published 2025-07-01“…<b>Results:</b> Twenty-four studies comprising 1169 patients were included (mean age: 72.45 years; mean symptom duration: 33.04 months). Most studies reported clinical improvement after VP shunting. …”
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79405
Inequalities in local government expenditure on environmental and regulatory services in England from 2009 to 2020: a longitudinal ecological study
Published 2024-12-01“…The share of ER expenditure spent on FSIC decreased by 13.4% in the most deprived authorities compared with 6.3% in the least deprived areas.Conclusion The unequal distribution of cuts shows the need for increased and equitable investment into these services to enable resilience to emerging infectious disease threats and to prevent the widening of health inequalities.…”
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79406
Writing the future of biogeography
Published 2018-12-01“…Nonetheless, the changes currently underway may be among the most radical. The five major biogeography journals (<em>Diversity and Distributions, Ecography, Frontiers of Biogeography, Global Ecology and Biogeography, and Journal of Biogeography</em>) are indicative of the major undercurrents in publishing today: two are society owned, three are owned by a private publisher; two are open access, three are reader-pays; four are published by a for‐profit publisher, one is not; three are double-blind review, two are the traditional single blind. …”
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79407
An Activin Receptor IA/Activin-Like Kinase-2 (R206H) Mutation in Fibrodysplasia Ossificans Progressiva
Published 2013-01-01“…Mutation analysis was performed in which genomic DNA as PCR amplified using primers flanking exons 4 and 6, and PCR products were digested with Cac8I and HphI restriction enzymes. The most informative results were obtained with the exon 4 flanking primers and the Cac8I restriction enzyme, which generated a 253 bp product that carries the ACVR1 617G>A mutation, which causes an amino acid substitution of histidine for arginine at position 206 of the glycine-serine (GS) domain, and its mutation results in the dysregulation of bone morphogenetic protein (BMP) signalling that causes FOP.…”
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79408
The Relationship of Antimicrobial Sensitivity and Biofilm Formation of Salmonella spp. Isolated from Broiler Chicken Farms in Biskra, Algeria
Published 2025-04-01“…The results also showed a difference in the ability of the isolates to produce biofilms; most of them were weak, medium and non-productive biofilms at a rate of 55.56%, 37.78% and 6.67%, respectively. …”
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79409
MULTIDISCIPLINARY APPROACH TO STUDY MIGMATITES: ORIGIN AND TECTONIC HISTORY OF THE NASON RIDGE MIGMATITIC GNEISS, WENATCHEE BLOCK, CASCADES CRYSTALLINE CORE, WA, USA
Published 2008-12-01“…This composite fabric is faulted and folded by mesoscopic structures. The most strongly foliated leucosomes (gneissic tonalites) are generally concordant with the regional trend of foliation, while weakly foliated leucosomes (tonalites) and pegmatite veins crosscut host rock and tonalite gneisses. …”
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79410
Steroid-sparing effect of levilimab in rheumatoid arthritis in real practice
Published 2025-01-01“…During the observation a favorable safety profile of LVL was noted. The most frequently reported adverse event was an increase in alanine aminotransferase and aspartate aminotransferase, recorded in 41 patients (56.1%). …”
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79411
Role of radionuclide assessment of global and regional mechanical dyssynchrony of the heart in prognosis of cardiac resynchronization therapy in patients with heart failure
Published 2023-09-01“…Regional MD scintigraphy parameters increase the predictive value of REVG in CRT candidates. The most informative in this regard are the PSD of RV free wall and LV anterior wall, as well as the HBW of LV lateral wall.…”
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79412
TRANSIENT ELECTROMAGNETIC SOUNDING IN 2D, 3D, AND 4D MODES: SEQUENCE OF GEOLOGICAL EXPLORATION ACTIVITIES
Published 2021-10-01“…In oil and gas exploration, the most commonly used technique is the near-field transient electromagnetic sounding (TEM). …”
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79413
Systematic Review and Meta-Analysis of Congenital Toxoplasmosis Diagnosis: Advances and Challenges
Published 2024-01-01“…In meta-analysis, PCR in AF showed the best performance for CT diagnosis based on the highest summary sensitivity (85.1%) and specificity (99.7%) added to lower magnitude heterogeneity. Conclusion. Most of the assays being researched to diagnose CT are basically the same traditional approaches available for clinical purposes. …”
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79414
Microtopography-induced changes in cell nucleus morphology enhance bone regeneration by modulating the cellular secretome
Published 2025-07-01“…Abstract Nuclear morphology plays a critical role in regulating gene expression and cell functions. While most research has focused on the direct effects of nuclear morphology on cell fate, its impact on the cell secretome and surrounding cells remains largely unexplored. …”
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79415
How do children’s hospitals address health inequalities: a grey literature scoping review
Published 2024-01-01“…This scoping review provides examples of approaches on three scales delivered at hospitals across high-income countries. Hospitals with the most comprehensive and extensive range of approaches employ dedicated staff within the hospital and community. …”
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79416
Preparing Lawyers for the Twenty-First Century
Published 1992-01-01“…These truisms include the following: that education is a life-long enterprise; that most higher education should be self-education; that the main role of undergraduate education is learning how to learn; that standard distinctions between academic and practical, theory and practice, liberal and vocational are false dichotomies that are mischievous as well as misleading; and that any body of lawyers worth preserving must take seriously its claims to be a learned profession. …”
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79417
Exploring the role of civil society organizations (CSOs) in promoting the uptake of the human papillomavirus (HPV) vaccine for cervical cancer prevention in nine Nigerian states
Published 2025-08-01“…Abstract Background Arising from abnormal growth in the cervical epithelium, cervical cancer is recognized as the fourth most common cancer affecting women globally. The Human Papillomavirus (HPV) vaccine was designed to vaccinate girls against HPV by age 15 to prevent cervical cancer. …”
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79418
Microbiota-derived acetate suppresses sympathetic outflow via olfactory receptor 59 in the rostral ventrolateral medulla
Published 2025-06-01“…The RNA sequencing results indicated that Olr59 was the most highly expressed short-chain fatty acids receptor in the rat RVLM and was upregulated in spontaneously hypertensive rats (SHR). …”
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79419
The Role of Inflammatory, Anti-Inflammatory, and Regulatory Cytokines in Patients Infected with Cutaneous Leishmaniasis in Amazonas State, Brazil
Published 2014-01-01“…The isolates were identified as Leishmania guyanensis, L. naiffi, and L. amazonensis. Most (64%) of the patients were male ranging in age from 18 to 58 years. …”
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79420
Neanderthal coasteering and the first Portuguese hominin tracksites
Published 2025-07-01“…Here we describe the first two hominin tracksites found in the southwestern most region of Europe. At Monte Clérigo, dated to 78 ± 5 ka, trackways of three individuals demonstrate how Neanderthals navigated dune landscapes. …”
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