The Effect of Piracetam Administration on Cerebral Palsy Prevention in Rat Fetuses Born To Pregnant Rats by Determining Bdnf Levels in Brain Tissue by Dudy Aldiansyah, Sarma Nursani Lumbanraja, Khairul Putra Surbakti, Isti Ilmiati Fujiati, Agus Sulistyono

“… Cerebral palsy is the most common cause of disability in children worldwide, estimated prevalence of 1.5–4 per 1000 children; the  higher prevalence in low-resource populations (up to 10 per 1000 children). …”
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Log odds of positive lymph nodes as a prognostic marker in resectable triple negative breast cancer by Chenchen Zheng, Jingjing Huang, Shengping Zhao, Yuxi Peng, Qian Xiong, Xumei Li, Jiangming Xiang, Jie Jian

“…Stratified analysis by LODDS and age revealed that BCS followed by radiotherapy conferred the most substantial survival benefit. LODDS is a reliable prognostic marker for survival outcomes in resectable nonmetastatic TNBC. …”
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Good Practices in the Clinical Management of Patients with Acute Coronary Syndrome: Retrospective Analysis in a Third-Level Hospital in Mexico by Héctor E. Flores-Salinas, Fidel Casillas-Muñoz, Yeminia Valle, Cesar M. Guzmán-Sánchez, Jorge Ramon Padilla-Gutiérrez

“…There are at least 20% more diagnoses of ST-segment elevation myocardial infarction in this hospital compared to the latest national reports in Mexico. The most common risk factors were type 2 diabetes mellitus, hypertension, smoking, and dyslipidaemia. …”
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Analysis of the prognostic and immune role of MCM6 in pan-cancer and experimental validation in lung adenocarcinoma cells by Minghua Liao, Chunyu Li, Jun Lv, Rui Yang, Jun Li, Ke Wu, Jiayi Zhang, Qian Zhu, Yingchang Shi, Xianming Zhang

“…MCM6 is highly expressed and is a prognostic risk factor in most tumors. MCM6 expression is significantly associated with the infiltration of immune cells (especially MDSCs) in a variety of tumors. …”
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DYNAMICS OF CLINICAL AND BIOCHEMICAL PARAMETERS AND FUNCTIONAL STATE OF THE AUTONOMIC NERVOUS SYSTEM IN PATIENTS WITH ACUTE HEPATITIS B WITH CHRONIC ALCOHOL USE IN HEPATOTOXIC DOSE... by O. O. Furyk, O. V. Ryabokon, T. E. Onishenko, V. G. Savelyev, О. P. Mashko

“…Frequency of clinical signs in most patients in both groups was not statistically different (p>0,05). …”
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Impact of Phenological and Lighting Conditions on Early Detection of Grapevine Inflorescences and Bunches Using Deep Learning by Rubén Íñiguez, Carlos Poblete-Echeverría, Ignacio Barrio, Inés Hernández, Salvador Gutiérrez, Eduardo Martínez-Cámara, Javier Tardáguila

“…The results show that the fruit-set stage under daylight provided the best performance (F1 = 0.77, R² = 0.97), while for inflorescences, night-time imaging yielded the most accurate results (F1 = 0.71, R² = 0.76), confirming the benefits of artificial lighting in early stages. …”
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Early Detection of Pancreatic Cancer: Current Advances and Future Opportunities by Zijin Lin, Esther A. Adeniran, Yanna Cai, Touseef Ahmad Qureshi, Debiao Li, Jun Gong, Jianing Li, Stephen J. Pandol, Yi Jiang

“…Pancreatic ductal adenocarcinoma (PDAC) remains among the most lethal malignancies, with a five-year survival rate below 12%, largely attributable to its asymptomatic onset, late-stage diagnosis, and limited curative treatment options. …”
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Hydrolysis Patterns of Different Crystalline Swollen Starches by β-Amylase by Xinyu WANG, Miao SHAO, Yi JIANG, Bin ZHANG, Xiong FU, Chunhong QIU, Feng ZHAO, Qiang HUANG

“…At temperatures below 100 ℃, granular integrity can be retained by most starches with different swelling power. To investigate the hydrolysis behavior of β-amylase on different crystal types of expanded starch, expanded starch was prepared from waxy corn starch (A-type crystal) and potato starch (B-type crystal), and the effects of β-amylase on the hydrolysis rate, viscosity, apparent morphology, thermodynamic properties, crystallization characteristics, and molecular structure of expanded starch were explored. …”
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Phenotyping and combining ability analysis of sorghum [sorghum bicolor (l) Moench] genotypes in dryland environments by Temesgen Begna, Techale Birhan, Taye Tadesse

“…This signified the traits were principally governed by additive gene action and early generation selection was the most preferred strategies for further improvement. …”
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Pharmacists’ Experiences on Adverse Drug Reactions in Saudi Arabia: A Cross-Sectional Study by Dalal Salem Bakheit Aldossari, Naeema Taha Alshalaan, Khuloud Salem Alshammari, Fatima Ahmed Lubbad, Mudhi Ratyan Alanazi, Neamah Ahmed Lubbad, Nada Suliman Fahad Alessa, Sheraz Ali

“…A majority (<i>n</i> = 251, 82.3%) indicated direct patient encounters, while 67.2% (<i>n</i> = 205) reported observing suspected ADRs in the preceding 12 months. Most respondents filed ADR reports to the Saudi Food and Drug Administration/National Pharmacovigilance Centre (HCP = 103, CP = 60) and hospital drug information centers (HCP = 89, CP = 64), with online forms being the favored mode (HCP = 122, CP = 96). …”
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Levels and changes in cognitive, mental, and physical health as correlates of attitudes to aging in very old age by Serena Sabatini, Serena Sabatini, Katya Numbers, Nicole A. Kochan, Perminder S. Sachdev, Perminder S. Sachdev, Henry Brodaty

“…However, among cognitive, mental, and physical health indicators, changes in depressive symptoms are the most correlated with perceived psychosocial loss in very old age.…”
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Physical activities awareness and practice among the healthcare professions students in Saudi Arabia by Eidan M. Al Zahrani, Salah H. Elsafi, Abdulwahab H. Alharbi, Wadha S. Alotaibi, Aqeelah A. Alyahya, Sarah A. Alqahtani, Shatha M. Al Thabet, Shrooq O. Al Harbi, Ahmed A. Adam, Abdallah A. Al Shehri

“…Participants identified walking as the most common form of exercise, 60.64%, followed by moderate-intensity activity,16.15%, and vigorous-intensity activity, 9.17%, while 14.04% reported no practice. …”
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Simultaneous Determination of Nirmatrelvir and Ritonavir in Human Plasma by HPLC-MS/MS by T. N. Komarov, P. K. Karnakova, O. A. Archakova, D. S. Shchelgacheva, N. S. Bagaeva, I. E. Shohin, K. Ya. Zaslavskaya, P. A. Bely

“…Therefore, development of coronavirus disease 2019 (COVID-19) drugs is the most urgent global issue. Nirmatrelvir and ritonavir combination is an oral antiviral drug combination with activity against SARS-CoV-2. …”
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High-altitude HEMS missions—a retrospective analysis of 3,564 air rescue missions conducted between 2011 and 2021 by Eva Klocker, Lea Wienandts, Dario Josi, Simon Rauch, Roland Albrecht, Jürgen Knapp, Urs Pietsch

“…For this reason, however, the number of emergencies in remote areas, which can be reached most rapidly by helicopter, has also increased. Methods We retrospectively reviewed all rescue missions conducted by the Swiss Air Ambulance (Rega) in the period 2011–2021 that were carried out at an altitude of more than 2,500 m above sea level. …”
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ALKBH5 Promotes Breast Cancer Stemness Through Regulating Wnt/&amp;beta;-Catenin Signaling by Wang K, Wang K

“…Kailin Wang,1,2 Kaiting Wang1 1Institute for Hepatology, National Clinical Research Center for Infectious Disease, Shenzhen Third People’s Hospital, The Second Affiliated Hospital, School of Medicine, Southern University of Science and Technology, Shenzhen, 518112, People’s Republic of China; 2Breast Cancer Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510289, People’s Republic of ChinaCorrespondence: Kaiting Wang, Institute for Hepatology, National Clinical Research Center for Infectious Disease, Shenzhen Third People’s Hospital, The Second Affiliated Hospital, School of Medicine, Southern University of Science and Technology, Shenzhen, 518112, People’s Republic of China, Tel +86-0755-61238989, Email kattywang19@163.comBackground: Breast cancer is the most prevalent disease and the fourth cause of cancer death among female globally. …”
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Areca nut extract increased stromal tumor-infiltrating lymphocytes in 4-nitroquinoline-1-oxide-tumor-induced Sprague-Dawley rats [version 4; peer review: 1 approved, 2 approved wit... by Dina Keumala Sari, Cut Fera Novita, Poppy Andriany, Liza Meutia Sari

“…Background Oral squamous cell carcinoma (OSCC) is one of the most common oral cancers with a high mortality rate. …”
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Late Holocene history of the Shkhelda Glacier, Northern Caucasus, according to remote sensing, dendrochronology and cosmogenic (¹⁰Be) dating of moraines by O. N. Solomina, I. S. Bushueva, V. Jomelli

“…Judging from historical and cartographic data, the Shkhelda Glacier was advancing in the 1880–1910, when most glaciers in the region gradually decreased in size after reaching their maximum during the Little Ice Age. …”
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Presentation and Outcomes of Patients with Colorectal Malignancies Undergoing Emergency Surgery – Experience from a Tertiary Care Centre in India by Yashwant Sakaray, Naveeen Maheshwari, Manish Thakur, Sisira J, Kailash Kurdia, Santosh Irrinki, Satish Subbiah Nagaraj, Lileswar Kaman

“…Intestinal obstruction was the most common presentation. A total of 24 colorectal resections (54.6%) were performed, along with 14 diversion colostomies (31.8%) and 6 diversion ileostomies (13.6%). …”
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Novel 3-Methyl-1,6-Diazaphenothiazine as an Anticancer Agent—Synthesis, Structure, and In Vitro Anticancer Evaluation by Beata Morak-Młodawska, Emilia Martula, Małgorzata Jeleń, Artur Beberok, Zuzanna Rzepka, Sebastian Musiał, Szymon Małek, Marta Karkoszka-Stanowska, Dorota Wrześniok

“…An in vitro panel of experiments was assessed using the WST-1 assay and cytometric techniques. The two most promising compounds were analyzed for their effect on intracellular GSH levels, mitochondrial membrane potential and their ability to initiate DNA fragmentation to determine the potential mechanism of both cytotoxic and proapoptotic activity. …”
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Emergency physician perspectives on initiating buprenorphine/naloxone in the emergency department: A qualitative study by Kathryn A. Dong, Karine J. Lavergne, Ginetta Salvalaggio, Savannah M. Weber, Cindy Jiaxin Xue, Andrew Kestler, Janusz Kaczorowski, Aaron M. Orkin, Arlanna Pugh, Elaine Hyshka

“…Participants had a median of 10 years of experience, and most (29/32) worked in urban settings. Clinical care of patients with opioid use disorder was found to be variable and physician dependent. …”
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