Ameliorative effects of Sesamum Indicum aqueous extract on Letrozole-induced polycystic ovary syndrome in adult female rats and formulation of sesame syrup by Zeynab Khosrowpour, Shamim Sahranavard, Fatemeh Jafari, Mojgan Tansaz, Shirin Fahimi, Mehrdad Faizi

“…The 400 mg/kg dose was found to be the most effective in this experiment.…”
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Postoperative adjuvant chemotherapy in patients with stage II early onset colorectal cancer: exploration and discovery using real-world data and the SEER database by Shikun Cao, Yihuan Qiao, Lijun Wu, Qi Chen, Kai Tian, Jipeng Li, Chungen Xing

“…However, T4 stage patients receiving ACT demonstrated prolonged survival compared to non-ACT counterparts, particularly after three years (P = 0.007), as identified by landmark analysis.ConclusionsMost stage II EOCRC patients might yield limited benefits from postoperative ACT, with the sole exception of those at T4 stage, who could experience long-term clinical advantages.Clinical Trial Registrationhttps://clinicaltrials.gov/study/, identifier NCT06308354.…”
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Application of Machine Tool Thermal Error Compensation in Digital Twin-based System by MA Chi, LI Minging, LIU Jialan, HE Jialong, HUA Chunlei, WANG Liang

“…The implementation of this digital twin system was crucial to reducing the geometric errors affecting the most critical sizes of the considered benchmark by about 75. 00%.…”
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Strobing of Radar Marks for Trajectory Filtration in a Body-Fixed Frame by Konstantin K. Vasiliev, Alexey V. Mattis, Oleg V. Saverkin

“…This form corresponds to the most probable location of the marks of the tracked target. …”
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The reprogramming impact of SMAC-mimetic on glioblastoma stem cells and the immune tumor microenvironment evolution by Qiong Wu, Jianan Chen, Anders E. Berglund, Dongliang Du, Robert J. Macaulay, Arnold B. Etame

“…Abstract Background Intrinsically resistant glioma stem cells (GSCs) in the setting of a highly immunosuppressive tumor microenvironment (TME) remain the most predominant phenomenon leading to unfavorable therapeutic outcomes in glioblastoma (GBM). …”
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Hydrogeochemical characterization and quality assessment of groundwater resources in Amtali Upazila, Barguna: A study of coastal Bangladesh by Afroz Jahan, Sukhen Goswami, Md. Jakir Hossain, Sujan Mallik, Mehedi Hasan Ovi, Mahfuzur Rahman, Mahmud Al Noor Tushar, Sarmin Sultana, Dhiman Kumer Roy

“…Water quality indices, including the Water Quality Index (WQI) and Sodium adsorption ratio (SAR), Sodium Concentration (SC), and Kelly's Ratio (KR), indicate that 73.9 % of the samples are suitable for drinking, whereas most samples are unsuitable for irrigation. Multivariate statistical analysis (correlation matrix, cluster analysis, and principal component analysis) confirms that geogenic processes primarily influence groundwater quality. …”
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Association of psychosocial stress with the social environment, lifestyle and risk factors for cardiovascular diseases in middle-aged male Muscovites by M. B. Kotova, V. B. Rozanov, A. A. Aleksandrov, O. M. Drapkina

“…A high level of psychosocial stress in middle-aged men is associated with hypertension, sedentary lifestyle and lower values of most indicators of the social environment, lifestyle and quality of life. …”
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Tetramethylene Sulfone (TMS) as an Electrolyte Additive for High-Power Lithium-Ion Batteries by Wenting Liu, Gangxin Chen, Ningfeng Wang, Xianzhong Sun, Chen Li, Yanan Xu, Xiaohu Zhang, Xiong Zhang, Kai Wang

“…The findings indicate that the electrolytes with TMS ratios of 2 wt% and 5 wt% demonstrated good synergistic cathode–anode stability in the NCM//soft carbon system, and the electrolyte with a 5 wt% TMS ratio demonstrated the most significant improvement in the overall performance of the full battery.…”
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Embracing global biodiversity toward a better planet by Haigen Xu, Richard D. Gregory, Yun Cao, Riquan Zhang, Lirong Zhang, Michael Gill, Dandan Yu, Jianfeng Yi, Wei Liu, Hongmei Lin

“…Global biodiversity is the most essential component of the planet, and the Kunming-Montreal Global Biodiversity Framework (GBF) has been unanimously adopted by 196 parties worldwide in 2022 to achieve the global vision of a world of living in harmony with nature by 2050. …”
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Primary Health Care structure and vaccination coverage in Brazilian municipalities by Guilherme de Andrade Ruela, Alaneir de Fátima dos Santos, César Macieira, Sábado Nicolau Girardi, Daisy Maria Xavier de Abreu, Alice Werneck Massote, Jackson Freire Araújo, Antônio Thomaz Gonzaga da Matta Machado

“…BHU structures ranged from fair to good, with lower percentages in Cycle 1 and increases in Cycles 2 and 3 for most of the variables analyzed. The availability of immunobiologicals also improved over the cycles, despite a few exceptions. …”
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Effect of urea and squaramide IMPDH inhibitors on C. parvum: in vitro trial design impacts the assessment of drug efficacy by Anne-Charlotte Lenière, Amit Upadhyay, Jérôme Follet, Timothy P. O'Sullivan

“…Initial screening identified nine active compounds with the most potent candidates achieving IC50 values as low as 2.2 μM. …”
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Incident gabapentin prescribing associated with opioid and benzodiazepine/Z-drug prescribing – a population-based longitudinal study in primary care by Kristjan Linnet, Bjarni Pall Linnet Runolfsson, Johann Agust Sigurdsson, Johann Agust Sigurdsson, Larus Steinthor Gudmundsson

“…., ≥30 DDDs BZDs or Z-drugs were most likely to initiate gabapentin therapy (IRR 7.18: 95% CI 6.50–7.93). …”
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Probabilistic risk assessment of fifteen metal(loid)s and their mixtures in surface sediment of Hongze Lake (China) using the diffusive gradients in thin films (DGT) technique by Changjiang Ma, Yang-Guang Gu, Richard W. Jordan, Shi-Jun Jiang, Meirong Wang

“…The ecological risk quotient (RQ) values for Mn and Fe exceeded 1 at all sites, indicating substantial ecological risks, while copper (Cu) and arsenic (As) had RQ values near or above 1 at most sites. A joint probabilistic risk assessment using the species sensitivity distribution (SSD) method revealed a 30.31% probability of concurrent toxic effects on aquatic organisms. …”
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Characterization of a Vaginal <i>Limosilactobacillus</i> Strain Producing Anti-Virulence Postbiotics: A Potential Probiotic Candidate by Tsvetelina Paunova-Krasteva, Petya D. Dimitrova, Dayana Borisova, Lili Dobreva, Nikoleta Atanasova, Svetla Danova

“…The Lf53 lysates showed the most significant inhibition of violacein production across multiple assays, showing 29.8% reduction. …”
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DNA methylation remodeling in temozolomide resistant recurrent glioblastoma: comparing epigenetic dynamics in vitro and in vivo by Michela Buonaiuto, Mariella Cuomo, Davide Costabile, Federica Trio, Sara Ferraro, Ornella Affinito, Alberto De Bellis, Maria Laura Del Basso De Caro, Roberta Visconti, Lorenzo Chiariotti, Giuseppe Catapano, Rosa Della Monica

“…Abstract Background Glioblastoma is the most aggressive type of brain tumor and is associated with a poor prognosis. …”
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Epidemiological analysis of adverse pregnancy events and associated risk factors in the border area of Guangzhou and Foshan, China by Wei Kong, Qingju Huang, Peixi Wang

“…The incidence rates were 7.91% for pregnancy complications, 50.33% for pregnancy comorbidities, and 11.69% for fetal and adnexal abnormalities. The most common conditions detected were gestational diabetes (22.26%), thyroid disease (15.42%), anemia (9.60%), birth defects (4.65%), and viral hepatitis (3.32%). …”
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Carbonate sediment production in coastal wetlands: Periphyton contributions and diatom indicators by Samantha Hormiga, Evelyn E. Gaiser, Michael S. Ross, James W. Fourqurean, Rosario Vidales

“…Diatoms can provide a helpful link between biotic and abiotic processes, indicating where periphyton-driven mineral production contributes most to inorganic carbon cycling and mineral-driven elevation recovery and, hence, to resiliency to sea level rise.…”
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Characteristics of the spring common wheat variety ‘Balkysh’ by Danil F. Askhadullin, Damir F. Askhadullin, N. Z. Vasilova, M. R. Tazutdinova, I. I. Khusainova, G. R. Gaifullina

“…The variety ‘Balkysh’ is not inferior or superior in productivity and protein yield to the varieties most common in the Republic of Tatarstan; the mean productivity of the variety was 4.31 t/ha, protein yield was 0.54 t/ha. …”
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Physiological and Pharmacological Roles of FGF21 in Cardiovascular Diseases by Peng Cheng, Fangfang Zhang, Lechu Yu, Xiufei Lin, Luqing He, Xiaokun Li, Xuemian Lu, Xiaoqing Yan, Yi Tan, Chi Zhang

“…Cardiovascular disease (CVD) is one of the most severe diseases in clinics. Fibroblast growth factor 21 (FGF21) is regarded as an important metabolic regulator playing a therapeutic role in diabetes and its complications. …”
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Comparative Analysis of Physico-Chemical Properties of Parbhani Shakti sorghum and evaluation of its nutritional profile under different pre-treatments by Anushree R. K., Agarkar B. S., Pawar V. S.

“…Among the various pre-treatments applied, malting was found to be the most effective in improving the nutritional profile. …”
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