TSC complex decrease the expression of mTOR by regulated miR-199b-3p by Na Zhao, Qiuhong Xiong, Ping Li, Guangxin Chen, Han Xiao, Changxin Wu

“…Abstract The TSC complex formed by TSC1 and TSC2 is the most important upstream negative regulator of mTORC1. …”
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Virtual reality locomotion methods differentially affect spatial orientation and cybersickness during maze navigation by Petr Hořejší, Alena Lochmannová, Vojtěch Jezl, Matěj Dvořák

“…CBS showed comparable navigation performance to CTR, slightly outperforming CTR only in the most difficult mazes (108 ± 51 s vs. 115 ± 42 s, p < 0.05). …”
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Investigating the strength performance of 3D printed fiber-reinforced concrete using applicable predictive models by Lu Qianyang, Mei Song, AlAteah Ali H., Alsubeai Ali, Eldin Mohammad Mohie, Ahmed Hafez Mohamed

“…Sensitivity analysis exposed that for CS, water-binder ratio, silica fume, and water content were the most influential parameters, while load distribution, sand content, and fly ash had the highest impact for FS. …”
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Use of calcium hydroxyapatite and growth factors in endodontic therapy by Mitić Aleksandar, Živković Milan, Živković Dušan, Popović Lidija, Veličković Zorana, Miladinović Milan, Šubarić Ljiljana, Marjanović Dragan, Cvetković Andrijana

“…Hydroxyapatite (HAp) is one of the most commonly used calcium phosphate bioceramics with osteoconductive properties. …”
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Long-term gamma-aminobutyric acid (GABA) treatment fails to regain beta-cell function in longstanding type 1 diabetes in a randomized trial by Henrik Hill, Per Lundkvist, Georgios Tsatsaris, Bryndis Birnir, Daniel Espes, Per-Ola Carlsson

“…Safety concerns included elevated aspartate aminotransferase (AST) in nine subjects, leading to the withdrawal of two subjects. Most elevations were, however, transient with no dose-differences. …”
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Effectiveness of hemostatic agents to control external bleeding in military health by Laura Corrochano-Rodríguez, Beatriz Rodríguez Martín, Pedro Ángel Caro-Alonso

“…In the studies, the following hemostatic agents were used QuikClot®, HemCon®, Celox®, and ChitoGauze HemCon®, in most studies, hemostatic agents were more than 88 % effective in stopping, reducing, and controlling external hemorrhage in combat victims, especially in union areas, also decreasing morbidity and mortality. …”
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ASSESSMENT OF ADVANTAGES OF USING A DIFFUSION PULSATING APPARATUS FOR RECONSTRUCTION OF THE DIFFUSION SECTION OF A SUGAR FACTORY by D. P. Iovlev, M. I. Farakhov, R. R. Akberov, I. R. Stekolshchikov, A. V. Akhmerov, A. A. Sinyavin

“…The raw material for sugar production is sugar beet, mainly domestically produced. The locations of most sugar factories are small municipalities, for which they are the town-forming enterprises. …”
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Modeling the Transmission Routes of Hepatitis E Virus as a Zoonotic Disease Using Fractional-Order Derivative by Shaibu Osman, Binandam Stephen Lassong, Munkaila Dasumani, Ernest Yeboah Boateng, Winnie Mokeira Onsongo, Boubacar Diallo, Oluwole Daniel Makinde

“…The model can be extended to optimal control and cost-effectiveness analysis to determine the most effective control strategy that comes with less cost in the combat of the disease.…”
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Nonreciprocal surface plasmonic neural network for decoupled bidirectional analogue computing by Xiaomeng Li, Haochen Yang, Enzong Wu, Xincheng Yao, Ying Li, Fei Gao, Hongsheng Chen, Zuojia Wang

“…Abstract To address the burgeoning demand for computing capacity in artificial intelligence, researchers have explored optical neural networks that show advantages of ultrafast speed, low power consumption, ultra-high bandwidth, and high parallelism. However, most existing optical networks are reciprocal, where forward and backward propagation are intrinsically coupled. …”
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Analysis of pseudoscientific beliefs in quantum mechanics of high school students and teachers by Walter Sciarretta, Maria Bondani, Silvia Galano, Massimiliano Malgieri, Pasquale Onorato, Italo Testa

“…The data collected were analyzed using the following methods: confirmatory factor analysis to establish the validity of the instrument; multiple correspondence analysis, to transform categorical variables measuring sociocultural background into continuous variables; repeated measures analysis of variance and linear regression to describe which factors most influence students’ and teachers’ pseudoscientific beliefs. …”
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School-based health education effect on knowledge, attitude, and practices of dengue prevention among school children: a systematic review by Rahmat Dapari, Abdul Qayyum Jumidey, Rosliza Abdul Manaf, Mohd ‘Ammar Ihsan Ahmad Zamzuri, Mohd Rohaizat Hassan, Nazri Che Dom, Syed Sharizman Syed Abdul Rahim

“…However, knowledge appeared to be the most significant variable as all studies showed a significant increase in knowledge. …”
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IL-17 Receptor Signaling Negatively Regulates the Development of Tubulointerstitial Fibrosis in the Kidney by Kritika Ramani, Roderick J. Tan, Dong Zhou, Bianca M. Coleman, Chetan V. Jawale, Youhua Liu, Partha S. Biswas

“…Chronic inflammation has an important role in the development and progression of most fibrotic diseases, for which no effective treatments exist. …”
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Epidemiological and Occupational Pattern of Patch-Test Reactions to p-Tert-butylphenol-formaldehyde Resin in North-Eastern Italy, 1997–2021 by Luca Cegolon, Alessandro Badalini, Francesca Larese Filon

“…The overall prevalence of PTBP-FR sensitization was 1.11% (=341/30,629) of cases, with lower prevalence occurring in the Province of Trento/Bolzano/Rovigo (0.36%). The body area most frequently affected were the hands (36.32%), followed by face (19.52%) and legs (8.09%). …”
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Chronic heart failure and adherence to medication: methods for assessing adherence to therapy and unresolved issues by E. T. Guseinova, N. P. Kutishenko, Yu. V. Lukina, S. N. Tolpygina, V. P. Voronina, S. Yu. Martsevich

“…This problem remains one of the most urgent and difficult to solve in medicine, because it directly affects the effectiveness of treatment and the outcome of the disease. …”
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Assessment of the Scope of Work for Operational Control of Steel Underground Gas Pipelines, Taking Into Account the Organizational and Logistical Factor by N. V. Strutsky, V. N. Romaniuk

“…It should be mentioned that the work carried out during the inspection and further repair of gas pipelines is the most extensive and labor-consuming of all those performed on the linear part of the gas distribution system. …”
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A guide to selecting high-performing antibodies for ADNP (UniProt ID: Q9H2P0) for use in western blot, immunoprecipitation, and immunofluorescence [version 1; peer review: 2 approv... by Carl Laflamme, Vera Ruíz Moleón, Sara González Bolívar, Riham Ayoubi, Charles Alende, Maryam Fotouhi

“…While use of antibodies and protocols vary between laboratories, we encourage readers to use this report as a guide to select the most appropriate antibodies for their specific needs.…”
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Nation-Building in Kazakhstan: Ethno-Confessional Contexts by N. P. Kalashnikova, K. A. Baitureyeva

“…The management of ethno-professional processes is undoubtedly one of the most important aspects of the functioning of the State and the tasks of society. …”
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Transient left ventricular function deterioration after patent ductus arteriosus closure: A case series by Mohammad Reza Sabri, Chehreh Mahdavi, Hamid Bigdelian, Ali Reza Ahmadi, Mehdi Ghaderian, Bahar Dehghan, Davood Ramezani Nezhad

“…There is growing evidence of left ventricular decompensation following the closure of the patent ductus arteriosus, which most often happens early in the post-surgical time and improves on its own a few months after. …”
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COMPARATIVE ANALYSIS OF THE COMPOSITION OF THE TERRESTRIAL FAUNA AND FLORA OF THE TETHYS DESERT-STEPPE REGION OF PALEARARTICS, BIOGEOGRAPHIC BOUNDARIES OF THE CAUCASUS. MESSAGE 1.... by G. M. Abdurakhmanov, M. V. Nabozhenko, A. G. Abdurakhmanov, A. A. Teymurov, M. G. Daudova, M. Z. Magomedova, A. G. Gasangadzhieva, A. A. Gadzhiev, Yu. Yu. Ivanushenko, S. M. Klycheva

“…A large number of the common Tethys genera and species in all model groups attests to their fundamental role in the overall composition of the biota against the background of powerful autochthonous centers of species-formation and, most importantly, the formation and functioning of the Palaearctic desert-steppe belt as the Tethys ocean reduced.…”
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Bertolotti's syndrome in low-backache population: Classification and imaging findings by Reddy Ravikanth, Pooja Majumdar

“…Results: Of these patient groups, 134 were classified as positive for sacralization, which resulted in an incidence of 26.8%. The most common anatomical variant was Castellvi Type IA (7.6%). …”
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