Mesenchymal stem cells modified with a single-chain antibody against EGFRvIII successfully inhibit the growth of human xenograft malignant glioma. by Irina V Balyasnikova, Sherise D Ferguson, Sadhak Sengupta, Yu Han, Maciej S Lesniak

“…<h4>Background</h4>Glioblastoma multiforme is the most lethal brain tumor with limited therapeutic options. …”
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Secondary stroke evaluation in patients admitted for CRAO in a large national inpatient sample by Rukhsana G Mirza, Sahil Doshi, Jay B Bisen, Hanaina K Bains, Ariz Keshwani, Neena Cherayil

“…Echocardiograms (10%) were most frequently performed, followed by temporal artery biopsy (6.4%). …”
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Bend Coupling Through Near-Zero GVD Slow Light Photonic Crystal Waveguides by Emerson Goncalves Melo, Daniel Orquiza de Carvalho, Marco Isaias Alayo

“…Slow light propagation through photonic crystal (PhC) slab devices has great potential to reduce the size and power consumption of silicon photonic optical circuits. Most commonly, slow light routing through photonic crystals is achieved by using W1 waveguide bends operating near their cutoff frequencies. …”
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Metabolic and inflammatory responses reveal different adaptation to the transition period challenges in Holstein, Brown Swiss, and Simmental dairy cows by A. Catellani, M. Mezzetti, A. Minuti, L. Cattaneo, E. Trevisi

“…BRO had the highest concentration of reactive oxygen metabolites, ceruloplasmin, bilirubin, glutamate-oxaloacetate transaminase, γ-glutamyl transferase, and β-hydroxybutyrate, and the lowest concentration of paraoxonase, reflecting the strongest activation of leukocytes and the most severe acute phase response. Together, these results highlight different metabolic and inflammatory conditions around calving in the three explored breeds.HIGHLIGHTS Holstein, Brown Swiss, and Simmental are dairy breeds selected for different purposes. …”
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Investigation of the synergistic effect of metformin and FX11 on PANC-1 cell lines by Melike Bayindir-Bilgic, Ezgi Duman, Deniz Turgut, Ayse Naz Kadikoylu, Nur Ekimci-Gurcan, Utku Ozbey, Aysegul Kuskucu, Omer. F. Bayrak

“…Abstract Background Pancreatic cancer is among the most aggressive and malignant tumors and is a leading cause of cancer-related mortality. …”
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Comparison of i-Gel as a Conduit for Intubation between under Fiberoptic Guidance and Blind Endotracheal Intubation during Cardiopulmonary Resuscitation: A Randomized Simulation St... by Hyun Young Choi, Wonhee Kim, Yong Soo Jang, Gu Hyun Kang, Jae Guk Kim, Hyeongtae Kim

“…We hypothesized that IGI using wire-reinforced silicone (WRS) tube could achieve endotracheal intubation most rapidly and successfully. Methods. In 23 emergency physicians, a prospective randomized crossover manikin study was conducted to examine the three intubation techniques using two kinds of endotracheal tubes. …”
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BLIS Fingerprinting as a Tool to Investigate the Distribution and Significance of Bacteriocin Production and Immunity in <i>Streptococcus pyogenes</i> and <i>Streptococcus salivari... by John R. Tagg, John D. F. Hale, Liam K. Harold

“…The study of bacteriocins has significantly enhanced our understanding of microbial interactions, notably within the genus <i>Streptococcus</i>. Among the most functionally diverse and clinically relevant bacteriocins are those belonging to the lantibiotic class, which exhibit potent antimicrobial properties and are central to the competitive dynamics of streptococcal species. …”
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Vector surveillance of avian Plasmodium and West Nile virus in Culex mosquitoes from Doñana, a UNESCO World Heritage Site by Josué Martínez-de la Puente, Juliana Tamayo-Quintero, María José Ruiz-López, Jesús Veiga, Santiago Ruiz, Ana Vázquez, Laura Herrero, Ramón C. Soriguer, Jordi Figuerola

“…Conclusions These results represent the most taxon extensive survey of pathogens in mosquitoes in Doñana. …”
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Safety and effectiveness of fecal microbiota, live-jslm (REBYOTA) administered by colonoscopy for prevention of recurrent infection: 8-week results from CDI-SCOPE, a single-arm, p... by Sahil Khanna, David Yoho, Daniel Van Handel, Brian J. Clark, Tahany Awad, Beth Guthmueller, Daniel Armandi, Whitfield Knapple, Nasia Safdar, Brian Baggott, Karen Simon, Paul Feuerstadt

“…Overall, 18 participants (43.9%) experienced 33 TEAEs within 8 weeks, most of which were of mild (25/33; 75.8%) or moderate (5/33; 15.2%) severity. …”
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Residual limb modelling for optimal shape and bandaging in transfemoral amputees by Sudesh Sivarasu, Bhaveen Lalla, Chibuike Mbanefo, Roopam Dey, Michael Awood

“…Pressure readings for most models remained within 0.5 mmHg of the approximated ideal target of 20 mmHg, with only CM5 showing a statistically significant deviation (mean pressure: 18.2 mmHg, p = 0.01), suggesting potential limitations at higher limb volumes. …”
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Transcriptomic Modification in the Cerebral Cortex following Noninvasive Brain Stimulation: RNA-Sequencing Approach by Ben Holmes, Seung Ho Jung, Jing Lu, Jessica A. Wagner, Liudmilla Rubbi, Matteo Pellegrini, Ryan Jankord

“…Results show that inflammatory pathways, antidepressant-related pathways (GTP signaling, calcium ion binding, and transmembrane/signal peptide pathways), and receptor signaling pathways (serotonergic, adrenergic, GABAergic, dopaminergic, and glutamate) were most affected. Of the gene expression profiles induced by tDCS, some changes were observed across multiple current intensities while other changes were unique to a single stimulation intensity. …”
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A modified droplet vitrification method for cryopreservation of shoot tips from <i>in vitro</i> potato plants by T. A. Gavrilenko, N. A. Shvachko, N. N. Volkova, Yu. V. Ukhatova

“…Panis with colleagues in 2005 is the most widely used in genebanks. This paper provides a detailed description of the modified method of droplet vitrification, which is used for cryopreservation of apexes (shoot tips) of potato in vitro plants at the N.I. …”
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Effectiveness of a structured emotional literacy and stress management program for female heads of household: a two-year longitudinal study in Cartagena, Colombia, and Valencia, Ve... by Heidy Rico, Mario de la Puente, Florentino Rico, Tatiana Londoño

“…Stress management coefficients improved from −0.384 at 6 months to −0.645 at 24 months, while intervention adherence declined moderately from 0.845 to 0.734. The intervention was most effective for women with moderate baseline stress levels and at least primary education. …”
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Inhibitory Effect and Mechanism of Hexanal on the Maturation of Peach-Shaped <i>Phallus impudicus</i> by Hong He, Shuya Fan, Gan Hu, Beibei Wang, Dayu Liu, Xinhui Wang, Jinqiu Wang, Fang Geng

“…These blocked signal transductions inhibited the gene expression of most β-glucanases, chitinases and chitin synthases, further affecting cell wall reconstruction. …”
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Beyond clinical risk: tackling loneliness through a population health lens by Ananda Zeas-Sigüenza, Ananda Zeas-Sigüenza, Pablo Ruisoto, Pablo Ruisoto, Pablo Ruisoto, Kami Koldewyn, Ferran Muntané, Ferran Muntané, Joan Benach, Joan Benach

“…Recognizing its growing prevalence and health burden, the World Health Organization (WHO) has identified loneliness as a public health priority. To date, most research and interventions have focused on high-risk individuals, mainly within clinical populations, often addressing loneliness only after it becomes severe and entrenched. …”
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Targeting the retinoid signaling pathway with YCT-529 for effective and reversible oral contraception in mice and primates by Nadja Mannowetz, Sanny S. W. Chung, Soma Maitra, Md Abdullah Al Noman, Henry L. Wong, Narsihmulu Cheryala, Akash Bakshi, Debra J. Wolgemuth, Gunda I. Georg

“…It was assessed in mouse mating trials to determine the most effective dosing regimen to induce infertility in male mice and in male non-human primates to reduce sperm levels. …”
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The DRUG UTILIZATION EVALUATION OF MACROLIDES IN ENT OUTPATIENT DEPARTMENT IN TEACHING HOSPITAL PUNJAB, PAKISTAN. by Misbah naz, Ali Hassan Gillani, Muhammad Arsalan Amjad, Muhammad Qamar uz zaman, Muhammad Hassan Akbar, Sharjeel Ahmed, Jamshaid Akbar, Sameer Ali

“…All drug were prescribed from essential drug list (EDL). Azithromycin was the most commonly prescribed drug in ENT department, followed by clarithromycin. …”
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Photodynamic Efficiency of Xanthene Dyes and Their Phototoxicity against a Carcinoma Cell Line: A Computational and Experimental Study by Suelen T. G. Buck, Fernanda Bettanin, Ednilson Orestes, Paula Homem-de-Mello, Hidetake Imasato, Rommel B. Viana, Janice R. Perussi, Albérico B. F. da Silva

“…RB was the more cytotoxic dye against HEp-2 cell line and the most efficient photosensitizer in causing photoxidation of uric acid; nevertheless it was the only one characterized as being hydrophobic among the xanthenes studied here. …”
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Poly-IC enhances the effectiveness of cancer immunotherapy by promoting T cell tumor infiltration by Juan Wu, Hussein Sultan, Esteban Celis, Andres M Salazar, Valentyna I Fesenkova, Aaron E Fan, Diane Addis

“…Background Immunotherapies, such as immune checkpoint inhibitors and adoptive cell therapies, have revolutionized cancer treatment and resulted in complete and durable responses in some patients. Unfortunately, most immunotherapy treated patients still fail to respond. …”
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Predicting in-hospital mortality in ICU patients with lymphoma using machine learning models. by Ling Xu, Guang Tu, Zhonglan Cai, Tianbi Lan

“…SHAP analysis highlighted the critical role of BUN as the most important factor in mortality prediction, followed by platelets and PT. …”
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