Spatially distributed gradient-based calibration and parametric sensitivity of a spatialized hydrological model over 235 French catchments by Pierre-André Garambois, François Colleoni, Ngo Nghi Truyen Huynh, Ahmad Akhtari, Ngoc Bao Nguyen, Apolline El-Baz, Maxime Jay-Allemand, Pierre Javelle

“…Parameter analysis reveals stable and interpretable patterns: water balance parameters, especially production capacity (cp) and water exchange (kexc), are most sensitive, while routing parameters are less so. …”
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Barriers and facilitators to cervical cancer screening in the Eastern Mediterranean Region: a systematic review by Ramin Rezapour, Mohammad Saadati, Hassan Sarsour, Lamia Mahmoud, Moradali Zareipour, Soma Khezri

“…Abstract Background Cervical cancer is the sixth most common cancer among women in Eastern Mediterranean Region. …”
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Hydro chemical assessment of groundwater quality using pollution index, quality indexes, fuzzy-GIS, graphical and multivariate techniques from a mining region of Eastern India by Suvankar Naskar, Debashis Mandal, Brototi Biswas, Chaitali Mukherjee

“…The region has a dominant anion type of chloride and bicarbonate type. 17.70% of the region falls under “Most Moderate to Worst hazardous Zone” as per GWHI, though NSFWQI indicates that the entire region’s groundwater is unsafe to drink, except for a few pockets. …”
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Features of the Clinical Course and Prognosis of Severe Traumatic Brain Injury Outcomes by Y. B. Vasilyeva, A. E. Talypov, M. V. Sinkin, S. S. Petrikov

“…Traumatic brain injury (TBI) is one of the most important contemporary health issues. According to the World Health Organization, TBI is one of three leading causes of death in the world. …”
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Global, regional, and national burden of unintentional childhood poisoning, 1990–2021: an analysis of data from the Global Burden of Disease study 2021 by Wenqian Wang, Ding Yuan, Fang Yang, Yanxia Gao

“…IntroductionChildhood poisoning remains a significant global public health challenge, driving ongoing efforts to reduce its effect across countries and regions. However, most previous studies have been limited to individual medical centers or specific geographic areas, lacking a comprehensive global comparison. …”
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Comparative efficacy and safety of anticoagulant therapies in coronary artery disease: a network meta-analysis of randomized controlled trials by Huahua Cui, An Wang, Guoqiang Zhong

“…Abstract Background The most efficacious anticoagulant intervention for people with coronary artery disease (CAD) is still not clearly defined, highlighting the need for a comprehensive assessment of the available alternatives. …”
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Overexpression of WDFY2 inhibits prostate cancer cell growth and migration via inactivation of Akt pathway by Jianqing Wang, Xu Chen, Shijun Tong, Huihui Zhou, Jianliang Sun, Yuancheng Gou, Fei Wu, Jimeng Hu, Jianfeng Xu, Guanxiong Ding

“…Prostate cancer is the most commonly diagnosed malignancy and is the second leading deadly reason among male cancer. …”
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Mixture of common and uncommon pathways and genes regulating primary and secondary immunoglobulin M responses in chickens by Somayeh Kianpoor, Alireza Ehsani, Rasoul Vaez Torshizi, Ali Akbar Masoudi, Mohammad Reza Bakhtiarizadeh

“…Moreover, RNF220, ATP6V0B, KIF2C, and CDC20 genes were involved in most of the pathways related to both traits.…”
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Informed consent in genetic and genomic studies in Sub-Saharan Africa: a systematic review of bioethical issues by Yunqi Li, Deborah J. Bowen, Joon-Ho Yu

“…Returning results had potential advantages in building trust between participants and the research team; however, the most appropriate way to return results is under discussion. …”
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Improving Soil Health and Potato Productivity through Lime and Nitrogen Management in Northern Ethiopia by Awoke Wasae Argaw, Shegaw Habitu Armde, Million Haile Belay, Anteneh Agezew Melash, Ashenafi Timotiwos Erkalo, Amare Assefa Bogale

“…However, liming had no significant effect on most yield parameters except for the weight of medium and small tubers. …”
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The Molecular Breeding of Different Ecotype <i>Japonica</i> Varieties Resistant to Rice Blast with High Genome Collinearity by Shengyuan Zeng, Cancan Du, Yihao Yang, Qingfeng Hu, Chuang Li, Fang Feng, Min Guo, Dedao Jing, Tianzi Lin, Hongbing Gong, Changjie Yan

“…The Yangtze River Delta (YRD) is one of the most important <i>japonica</i> rice planting areas in China. …”
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Similarity of immune-associated markers in COVID-19 and Kawasaki disease: analyses from bioinformatics and machine learning by Wang Li, Wenjie Zhu, Xiangting Tang, Zhiting Peng, Jiaqi Ye, Shuping Nie

“…Abstract Background Infection by the SARS-CoV-2 virus can cause coronavirus disease 2019 (COVID-19) and can also exacerbate the symptoms of Kawasaki disease (KD), an acute vasculitis that mostly affects children. This study used bioinformatics and machine learning to examine similarities in the molecular pathogenesis of COVID-19 and KD. …”
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Unraveling the potential: mRNA therapeutics in oncology by Karol Gawalski, Karol Gawalski, Weronika Przybyszewska, Weronika Przybyszewska, Jaromir Hunia, Jaromir Hunia, Alicja Gawalska, Aleksandra Rymarz

“…They are focused on malignancies like melanoma, non-small cell lung cancer, prostate cancer, or pancreatic ductal adenocarcinoma, one of the most challenging cancers. While many trials are in early phases, some have advanced to phase 3 and have shown promising results in both safety and efficacy. …”
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Indoor High Precision Three-Dimensional Positioning System Based on Visible Light Communication Using Particle Swarm Optimization by Ye Cai, Weipeng Guan, Yuxiang Wu, Canyu Xie, Yirong Chen, Liangtao Fang

“…But unfortunately, in the matter of algorithm complexity and positioning accuracy, most existing VLC-based systems fail to deliver satisfactory performance. …”
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Which factors related to apical radiolucency may influence its radiographic detection? A study using CBCT as reference standard by Rocharles Cavalcante Fontenele, Eduarda Helena Leandro Nascimento, Hugo Gaêta-Araujo, Laís Oliveira de Araujo Cardelli, Deborah Queiroz Freitas

“…For PAN, apical radiolucency is most often detected in single-rooted teeth.…”
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Perioperative outcomes among older surgical patients with multimorbidity: a longitudinal study from Ethiopia by Amanuel Sisay Endeshaw, Fantahun Tarekegn Kumie, Simachew Amogne Debas, Bantayehu Sileshi

“…Among all geriatric patients, 130 (14.87%) had hypertension, 34 (3.89%) had diabetes mellitus, and 29 (3.32%) had cancer. The most common multimorbidity combination was hypertension and diabetes (18 cases). …”
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Folate-based binuclear Mn(II) chelates with 2,2’-bipyridine/1,10-phenanthroline as targeted anticancer agents for colon cancer cells by Mona S. Ragab, Marwa H. Soliman, Marwa M. Sharaky, Abdelrahman Saad, Mohamed R. Shehata, Mohamed M. Shoukry, Mohamed A. Ragheb

“…The prepared chelates exhibit significant cytotoxic effects against folate receptor-positive cell lines, with colon cancer HCT116 cells being the most affected. Furthermore, the anticancer mechanism of action on the HCT116 cell line was investigated by analyzing the wound healing, cell cycle profile, expression of pro-apoptotic and anti-apoptotic proteins, as well as examining the morphological changes in treated cells. …”
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Sensitivity of Fungal Microbe Aspergillus niger to New Synthetic Analogs of Natural Isocoumarin Antibiotics by V. T. Abaev, G. S. Kachmazov, A. V. Gutnov, A. Y. Tuaeva, P. M. Shpuntov

“…From the results presented in the present work, it follows that the investigated field cultures of Aspergillus niger are most sensitive to antimycotic drugs belonging to N-methylnaphthylmethylamine derivatives and polyene antimycotics — terbinafine (MMSC = 0–2 µg/cm3) and nystatin (MMSC = 4–8 µg/cm3, IE-1 = 1.69, IE-K2 = 1.51), which have a pronounced mycocidal effect. …”
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X-ray velocimetry provides temporally and spatially-resolved biomarkers of lung ventilation in small airways disease by Bradley W. Richmond, Michael G. Lester, Vincent Lui, Jonathan Dusting, Sarath Raju, Gregory I. Snell, Jessica B. Blackburn, Katrina Douglas, Robert F. Miller, Trishul Siddharthan, Andreas Fouras

“…Further, we identified a set of XV-derived biomarkers that could distinguish veterans with DR-CB from controls despite normal spirometry in most patients from both groups. Conclusions XV may provide a safe and widely-available strategy for diagnosing small airways disease while preserving spatial information. …”
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Green solvents and enzymes combined with advanced extraction techniques for the recovery of bioactive carotenoids and extractable/non-extractable polyphenols from grapefruit peels by Gloria Domínguez-Rodríguez, María Concepción García, María Luisa Marina

“…UAE (15 min, 30 % amplitude) followed by EAE (70 °C, 40 min) and MAE-NaDES using choline chloride:lactic acid (1:2, 50 % water, 50 °C, 6 min) yielded the most bioactive NEPs. HPLC-DAD-QTOF-MS analysis allowed to identified 19 polyphenols in both extracts, highlighting naringin as the majority, particularly in UAE-EAE extract. …”
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