Cost-effectiveness of biomarker-directed toripalimab plus chemotherapy for previously untreated extensive-stage small-cell lung-cancer in China. by Shuo Kang, Shan Zhao, Xiaohui Wang, Zhenhua Pan

“…<h4>Conclusions</h4>ITH-testing directed treatment was likely to be the most cost-effective first-line option compared with toripalimab plus chemotherapy and chemotherapy alone for patients with previously untreated ES-SCLC from the Chinese health-care system perspective.…”
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Effect of Fertilization Levels on Growth and Physiological Characteristics of Containerized Seedlings of <i>Vaccinium oldhamii</i> by Da Hyun Lee, Chung Youl Park, Do Hyun Kim, Jun Hyeok Kim, Hyeon Min Kim, Chae Sun Na, Wan Geun Park

“…A fertilization rate of 0.5 g·L⁻¹ proved to be the most economically and environmentally efficient for producing healthy seedlings. …”
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Using Polymeric Scaffolds for Vascular Tissue Engineering by Alida Abruzzo, Calogero Fiorica, Vincenzo Davide Palumbo, Roberta Altomare, Giuseppe Damiano, Maria Concetta Gioviale, Giovanni Tomasello, Mariano Licciardi, Fabio Salvatore Palumbo, Gaetano Giammona, Attilio Ignazio Lo Monte

“…The goal of vascular tissue engineering is to produce neovessels and neoorgan tissue from autologous cells using a biodegradable polymer as a scaffold. The most important advantage of tissue-engineered implants is that these tissues can grow, remodel, rebuild, and respond to injury. …”
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Regulatory effect of arginine metabolism enzymes on ethyl carbamate formation during the fermentation of Chinese yellow rice wine by FANG Ruosi, DONG Yachen, XU Tengyang, FAN Linlin, CHEN Qihe

“…Ethyl carbamate (EC) is a potential carcinogenic compound in most of fermented products. It widely exists in the fermented foods, especially alcohol beverages, such as grape wine, Japanese sake and Chinese yellow rice wine, etc. …”
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Current attitudes to testicular prosthesis insertion during radical orchidectomy—An international perspective by Anthony Emmanuel, Abi Kanthabalan, Cameron Alexander, Nikita Bhatt, Vinson Chan, Odunayo Kalejaiye, Krishna Narahari, Veeru Kasivisvanathan, Majed Shabbir

“…Of those that offered testicular prosthesis implantation, 28% did so as a secondary procedure after radical orchidectomy, rather than the time of radical orchidectomy (72%). The most frequently selected reasons for not offering testicular prosthesis implantation included concerns about delaying chemotherapy (41%), infection (33%), impaired cosmesis (17%) and lack of availability (17%). …”
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Brainwide Analysis of Functional Connectivity Patterns in Specific Phobia and Its Treatment by Markus Muehlhan, Judith Schäfer, Kevin Hilbert, Esther Seidl, Katja Beesdo-Baum

“…Background: Specific phobia (SP) is a prevalent mental disorder for which exposure-based treatments are the most effective. Little is known about the intrinsic functional connectivity of SP and its modification by treatment. …”
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Analyzing Key Performance Indicators for Mobility Logistics in Smart and Sustainable Cities: A Case Study Centered on Barcelona by Raquel Soriano-Gonzalez, Elena Perez-Bernabeu, Yusef Ahsini, Patricia Carracedo, Andres Camacho, Angel A. Juan

“…The focus of the paper then turns to Barcelona, Spain, where KPIs that matter most are analyzed. <i>Methods</i>: Using open data from the city council spanning from 2017 onwards, the study provides insights into the evolving mobility logistics landscape. …”
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Elite athletes’ overall oral health, values and related quality of life: a cross-sectional study by André Júdice, Diogo Brandão, João Botelho, Vanessa Machado, Luís Proença, Luciano M. A. Ferreira, Athanasios Stamos, Peter Fine, José João Mendes

“…Periodontal disease (55.1%), particularly gingivitis (51.8%), and dental caries (47.4%) were the two most common conditions, affecting nearly half of athletes. …”
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Mapping the landscape: A bibliometric analysis of AI and teacher collaboration in educational research [version 2; peer review: 2 approved] by Rajesh Kumar, Rakesh Kumar, Rekha Verma, Archana Singh, N.S Bohra, Arvind Nain

“…The findings show that education and information technology make the most significant contributions to this sector, followed by international studies on open and distance learning. …”
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Enhancing analogy-based software cost estimation using Grey Wolf Optimization algorithm by Taghi Javdani Gandomani, Maedeh Dashti, Sadegh Ansaripour, Hazura Zulzalil

“…Among the software estimation methods, analogy-based estimation (ABE) is one of the most popular ones. Although this method has been customized in recent years with the help of optimization algorithms to achieve better results, the use of more powerful optimization algorithms can be effective in achieving better results in software size estimation. …”
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The Knowledge and Application of Economics in Healthcare in a High-Income Country Today: The Case of Belgium by Baudouin Standaert, Désirée Vandenberghe, Mark P. Connolly, Johan Hellings

“…However, these evaluation methods only impacted at most 20% of the money circulating in healthcare. …”
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INNOVATIVE ASPECTS OF OPEN INGUINAL HERNIA SURGERY: REDUCING COMPLICATIONS AND PREVENTING RECURRENCES by К. Рахманов, О. Хужамов, С. Давлатов, Б. Хамдамов, С. Янченко, Н. Абдуллаєва, З. Джалілова

“… Inguinal hernias constitute a significant portion of surgical pathology and remain among the most common reasons for seeking surgical consultation. …”
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Pooled sequencing of 531 genes in inflammatory bowel disease identifies an associated rare variant in BTNL2 and implicates other immune related genes. by Natalie J Prescott, Benjamin Lehne, Kristina Stone, James C Lee, Kirstin Taylor, Jo Knight, Efterpi Papouli, Muddassar M Mirza, Michael A Simpson, Sarah L Spain, Grace Lu, Franca Fraternali, Suzannah J Bumpstead, Emma Gray, Ariella Amar, Hannah Bye, Peter Green, Guy Chung-Faye, Bu'Hussain Hayee, Richard Pollok, Jack Satsangi, Miles Parkes, Jeffrey C Barrett, John C Mansfield, Jeremy Sanderson, Cathryn M Lewis, Michael E Weale, Thomas Schlitt, Christopher G Mathew, UK IBD Genetics Consortium

“…The contribution of rare coding sequence variants to genetic susceptibility in complex disorders is an important but unresolved question. Most studies thus far have investigated a limited number of genes from regions which contain common disease associated variants. …”
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Grapevine cell culture-based biostimulant alleviates salt stress in tomato seeds by José Manuel Martí-Guillén, Sara Esperanza Martínez-Lorente, María Ángeles Pedreño, Lorena Almagro, Ana Belén Sabater-Jara

“…These adverse soil and climate conditions affect crop yield, especially when they affect the germination process, the most critical phase of the plant developing process. …”
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Interpersonal and intrapersonal leadership competencies: an interpretative phenomenological analysis on effective leadership strategies by Marion Koreen Andrea Aquino, Alicia Mae Bumacod, Arizzandra Gerriz Calapine, Jan Marie Therese Yaco, Margarett Luz Dimailig, Avon Pearl Amores, Joseph Francisco

“…Thus, it is valuable to explore and identify competencies possessed by competent leaders.MethodsThe study utilized an Interpretative Phenomenological Analysis (IPA) approach to have a detailed exploration of the strategies and practices leaders find most effective in navigating complex organizational challenges, such as strategy adoption, teamwork improvement, client relationship management, ethical decision-making, and industry adaptation. …”
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Factors associated with neonatal mortality in the African Great Lakes region: A pooled analysis of national surveys by Blessing Jaka Akombi, Pramesh Raj Ghimire, Andre Masumbuko Renzaho

“… # Methods The study used cross-sectional data from the most recent Demographic and Health Survey of countries in the African Great Lakes region. …”
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Safety of BIOMODULINA T® in the Cuban population before and after its use for COVID-19 prevention by Mary Carmen Reyes Zamora, Suset Rodríguez Chávez, Raúl Lázaro Castro Almarales, Iris Rodríguez Iglesias, Ismary Alfonso Orta, Giset Jiménez López, Liliam Rodríguez Rivera, Alexis Labrada Rosado

“…Local reactions at the administration site, headache and fever continue to be the most frequent ADR. Conclusions: Even with the unprecedented widespread use of BIOMODULINA T® during the COVID-19 pandemic, the excellent safety profile of this product was maintained.…”
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Vascular wall structure and function in patients with CHD, AH, and their combination by V. K. Fedulov, G. N. Soboleva, A. N. Rogoza, T. V. Balakhonova, M. I. Tripoten, Yu. A. Karpov

“…Patients with CHD and AH were characterised by the highest levels of vascular risk factors, vascular wall remodelling, atherosclerosis of lower extremity arteries, and increased vascular wall stiffness. FDVD was most affected in CHD patients with such risk factors as hyperlipidemia, overweight, or smoking. …”
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Journey across extrinsic tactics for power improvements of triboelectric energy harvesting beyond intrinsic materials and device structures: A concise review by Ahmed Mahfuz Tamim, Yebin Lee, Jung Hwan Park, Geon-Tae Hwang, Chang Kyu Jeong

“…However, the practical application of TENGs largely depends on their power output and efficiency. The most promising approaches involve the optimization of material selection, surface modification, and chemical modification techniques to increase the triboelectric effect. …”
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Replicating Current Procedural Terminology code assignment of rhinology operative notes using machine learning by Christopher P. Cheng, Ryan Sicard, Dragan Vujovic, Vikram Vasan, Chris Choi, David K. Lerner, Alfred‐Marc Iloreta

“…Across all performance metrics, CV and NB was most overall the best combination of vectorizer and ML algorithm across CPT codes and produced the single best AUC, 0.984. …”
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