Virtual screening, molecular docking, and molecular dynamics simulation reveal new insights into RNA polymerase inhibition for anti-tuberculosis drug discovery by Taufik Muhammad Fakih, Farendina Suarantika, Aulia Fikri Hidayat, Dwi Syah Fitra Ramadhan, Muchtaridi Muchtaridi

“…MM-PBSA analysis revealed that ZINC000252693842 had the most favourable binding energy at −106.097 ± 24.664 kJ/mol, followed by ZINC001286671821 at −89.201 ± 22.647 kJ/mol, and ZINC000253654686 at −43.832 ± 23.748 kJ/mol. …”
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Analysis of microbial communities in allogeneic matured muskrat musk and natural musk by Chengli Zheng, Youhao Wu, Guijun Zhao, Dejun Zeng, Xiaolan Feng, Chenglu Zhang, Hang Jie, Jibin Zhu

“…According to PICRUSt2 analysis, energy metabolism and amino acid metabolism were the most prominently represented functional categories in D2. …”
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Economic costs of rabies post-exposure prophylaxis and healthcare utilization patterns post animal bites: An experience from a private healthcare facility in Bhubaneswar, Odisha, I... by Das Ayesha, Singh Snigdha, Bhowmick Sneha, Mohapatra Ipsa

“…PEP Non-adherence was mostly due to the high cost of treatment (88.5%). …”
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Antimicrobial Potential of Albizia lebbeck Extracts for Sustainable Sheepskin Preservation and Leather Production by Abdullahi, M. S., Bernard Egwu Igiri, Bitrus Habila, Mohammed, S. Y., Akabuogu, E. P., Adeyi, O. A., Suleiman, H., Yakubu, M. K.

“…Full Abstract: The use of salt to preserve hides/skins could result in the generation of quantities of total dissolved solids and is regarded as one of the most difficult pollutants to manage. Raw skins are preserved before processing them into leather, to protect the skin protein from microbial attack. …”
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Monitoring an open population of the middle-organized Siberian city: fifteen-years trends of arterial hypertension in men by E. V. Akimova, E. I. Gakova, M. M. Kayumova, T. I. Petelina

“…Arterial hypertension remains one of the most common diseases in the developed countries of the world, while there is a tendency to increase the frequency of arterial hypertension as the level of urbanization increases. …”
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Nanocomposite Apatite-biopolymer Materials and Coatings for Biomedical Applications by L.F. Sukhodub, G.O. Yanovska, L.B. Sukhodub, V.M. Kuznetsov, O.S. Stanislavov

“…Proposed natural polymers (Na alginate, chitosan) are the most perspective because they have bacteriostatic properties for a vast number of aerobic and anaerobic bacteria, high biocompatibility towards the connective tissue, low toxicity, an ability to improve regenerative processes during wounds healing, degradation ability with the creation of chemotaxic activity towards fibroblasts and osteoblasts. …”
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Predictors of mortality and ICD shock therapy in primary prophylactic ICD patients-A systematic review and meta-analysis. by Leonard Bergau, Tobias Tichelbäcker, Barbora Kessel, Lars Lüthje, Thomas H Fischer, Tim Friede, Markus Zabel

“…<h4>Limitations</h4>Individual patient data were not available for most studies.<h4>Conclusion</h4>In this meta-analysis of contemporary clinical studies, all-cause mortality is predicted by a variety of clinical characteristics including LVEF. …”
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An Improved Soil Moisture Downscaling Method Based on Soil Properties and Geographical Divisions over the Loess Plateau by Lei Han, Zheyuan Miao, Zhao Liu, Hongliang Kang, Han Zhang, Shaoan Gan, Yuxuan Ren, Guiming Hu

“…This study found the following: (1) The Normalized Difference Vegetation Index (NDVI) was the most important environmental factor in all divisions except the Flood Plain, and the Digital Elevation Model (DEM) was second only to the NDVI in the overall importance evaluation, both of which positively influenced SM. (2) SM variability increased and then decreased when SM was below 0.4 cm³/cm³, but showed a quadratic growth trend when exceeding this threshold. …”
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Reconfigurable optical synaptic weighting engine using a liquid crystal-based multimode interference coupler by Rajib Ratan Ghosh, Danqing Liu, Sander Reniers, Yuqing Jiao, Weiming Yao

“…Despite these efforts, most existing optical computing schemes encounter scalability challenges, given that the number of optical elements typically grows quadratically with the computational matrix size. …”
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The changing landscape of nontyphoidal salmonellosis: epidemiological patterns, imported cases and serovar distribution in Germany from 2012 to 2023 by Simon Brinkwirth, Achim Dörre, Klaus Stark, Anika Meinen

“…The incidence was higher in males and children under the age of five years. The most frequent serovars were S. Enteritidis and S. …”
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Awareness, Actions, and Predictors of Actions on Adverse Drug Reaction Reporting among Patients Attending a Referral Hospital in Southern Highland Tanzania by Nathanael Sirili, Manase Kilonzi, Dorkasi L. Mwakawanga, Juma A. Mohamedi, Joseph Matobo Thobias, Aurelia Clement, Davance Mwasomola, Stella E. Mushy

“…The majority of patients are not aware of what is ADR and the importance of ADR reporting. Most of the patients prefer to report ADR to healthcare providers. …”
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Global burden and risk factors of childhood cardiovascular disease (1990–2021) by Caixia Hou, Nan Zhang, Chao Liu, Weijun Gao

“…Gender and age analyses revealed higher incidence and mortality rates among female children compared to males, with the 10–14 age group being the most affected. Low temperatures were identified as a primary driver of CCVD burden, particularly in low-SDI regions.ConclusionThe global CCVD burden exhibits significant inequalities, largely driven by disparities in public health resource levels across regions with varying SDI. …”
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Local floral resources and edge density within the urban ecosystem promote larger and less variable body size in the great banded furrow bee, Halictus scabiosae by Lucie M. Baltz, Julienne de Vastey, Hanna Gardein, Felix Klaus, Henri Greil, Robert J. Paxton, Panagiotis Theodorou

“…Our findings highlight that food resources, semi-natural cover and edge density are the most significant environmental factors influencing body size shifts. …”
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Complications from the formation of preventive stomas in the surgical treatment of rectal cancer by I. I. Aliev, A. A. Smirnov, R. V. Pavlov, K. N. Komyak, D. A. Ivlev, N. A. Domanskiy, G. A. Sharygin, A. I. Nazmiev

“…Anastomotic leakage is one of the most severe complications of colorectal cancer surgery. …”
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Real-World Treatment Patterns and Outcomes Among Patients with Early Non-Small Cell Lung Cancer by Jennifer D. Deem, Zsolt Hepp, Joshua J. Carlson

“…Among the 54.6% receiving adjuvant, immune checkpoint inhibitors were the most common choice for definitive radiation (39.1%) and chemoradiation (73.7%) patients, while surgical patients predominantly received platinum-doublet therapy (37.0%). …”
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Regionalization of the Atmospheric Dust Cycle on the Periphery of the East Antarctic Ice Sheet Since the Last Glacial Maximum by G. Baccolo, B. Delmonte, S. Albani, C. Baroni, G. Cibin, M. Frezzotti, D. Hampai, A. Marcelli, M. Revel, M. C. Salvatore, B. Stenni, V. Maggi

“…Abstract Ice cores from inner East Antarctica provided some of the longest and most detailed climatic reconstructions and allowed understanding the relationships between atmospheric mineral dust and climate. …”
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Zygomaticofacial foramen in dry adult human skulls: a morphological study by Stanislav Malakhov, Petra Lukáčiková, Andrej Mifkovič, Ladislava Wsólová, Oleg Vovk, Štefan Polák

“…The distance from the ZFF to the infraorbital margin was 6.63 ± 2.09 mm, to the frontozygomatic suture was 26.24 ± 3.49 mm, to the zygomaticomaxillary suture was 19.75 ± 3.55 mm, to the zygomaticotemporal suture was 22.31 ± 3.98 mm, and to the most prominent point of the zygomatic bone was 8.03 ± 2.64 mm. …”
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Association of the Val66Met Polymorphism of the BDNF Gene with the Depression in a Mexican Population with Multiple Sclerosis by Brenda Viridiana Rabago-Barajas, Miguel Ángel Macías-Islas, Ana Miriam Saldaña-Cruz, Jesús Emmanuel Arana-Yepez, Eva Maria Olivas-Flores, Adriana Aguayo-Arelis

“…In MS, depression is the most frequent psychiatric disorder, with prevalence levels of 40 to 60%; to date, the cause is unknown. …”
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Effects of two different partial pressure of end-tidal carbon dioxide levels on cardiac function in patients undergoing carotid endarterectomy: a randomized controlled trial by Pei Wang, Chuanyu Liang, Yi An, Lixia Li, Zhongjia Li, Xuefei Jia, Hongyi Song, Tianlong Wang, Lei Zhao

“…Abstract Background Most patients undergoing carotid endarterectomy (CEA) are complicated with coronary artery disease and at high risk for cardiovascular events. …”
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Spectral parameters and biological activity of macromolecular compounds of humic etiology by M. V. Zykova, E. S. Trofimova, S. V. Krivoshchekov, A. A. Ligacheva, M. G. Danilets, L. A. Logvinova, G. A. Zholobova, O. F. Prishchepova, M. S. Yusubov, M. V. Belousov

“…The results of molecular spectroscopy showed that the most biologically active HAs have higher aromaticity and higher concentration of oxygen-containing functional groups. …”
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