Results of the Estimation of Biosimilarity of RinLiz^® (LLC «GEROPHARM», Russia) and Humalog^® (Lilly France, France) Using the Method of the Hyperinsulinemic E... by A. Yu. Mayorov, I. A. Fedotov, R. V. Drai, O. I. Avdeeva, I. E. Makarenko

“…Introduction. Insulin is the most effective hypoglycemic agent currently used in the clinical practice. …”
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Implementation of Intensified Tuberculosis Case Finding among People Living with HIV in Kampala, Uganda: A cross sectional study by David Okello, Angela Nakanwagi Kisakye, Justine Namakula, Esther Buryegyeya

“…Conversely, 90.0% (289/321) clients screened for at least one TB symptom with cough being the most frequently asked symptom 87.5% (281/321). Of 131 clients who were screened and reported having at least one TB symptom, 36.6% (48/131) were sent to the laboratory, 2.3% (3/131) for X-Ray and 61.1% (80/131) to pharmacy. …”
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HPV genotype distribution and cervical lesions in Chongqing: a comprehensive analysis of 229,770 females (2015‒2023) by Hongli Ding, Hao Jin, Yishu Tang

“…Among hr-HPV types, the five most common genotypes were HPV52 (4.55%), HPV16 (3.44%), HPV58 (2.94%), HPV56 (1.33%), and HPV39 (1.32%). …”
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Prevalence of Cognitive Impairment Amongst Older Adults and the Associated Risk Factors by Zana Faris Muhammed, Ali Hattem Hussain, Haitham Assem Abdalrazak

“…The severity of cognitive impairment is statistically significantly related to age group of 90-100 years old (80%), smokers (n = 21) is mostly mild [n=9/21 (42.85%)], the decrease in hearing acuity is more frequent among those with sever cognitive impairment [n= 9/24 (37.5%)], and most of the features were of mild severity [n= 45/69 (65.2%)]. …”
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Intracellular virion traffic to the endosome driven by cell type specific sialic acid receptors determines parvovirus tropism by Tania Calvo-López, Tania Calvo-López, Esther Grueso, Esther Grueso, Cristina Sánchez-Martínez, Cristina Sánchez-Martínez, José M. Almendral, José M. Almendral

“…Residues at three functional domains of the icosahedral capsid were substituted by rational design with peptides competing with the vascular endothelial growth factor. Most substitutions impaired virus maturation, though some yielded infectious chimeric virions, and substitutions in a dimple at the twofold axis that allocates sialic acid (SIA) receptors altered viral tropism. …”
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Identifying areas for action to create healthier diets in the London Borough of Newham: systems mapping with residents by Jessica Renzella, Adeola Agbebiyi, Ruby Nayyar, Saira Malik, Emily Ahmed, Seeromanie Harding, Peter Scarborough, Prachi Bhatnagar

“…Newham is ethnically diverse and within the 20% most deprived areas of England. To engage residents in public health action and encourage approaches that tackle the underlying causes of poor-quality diets, systems approaches were used to co-design healthy diet interventions with residents in Newham. …”
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A Dual-Frequency Faraday Laser by Tiantian Shi, Xiaolei Guan, Pengyuan Chang, Jianxiang Miao, Duo Pan, Bin Luo, Hong Guo, Jingbiao Chen

“…The linewidth of each laser mode is less than 33 kHz. Furthermore, the most probable linewidth of the beat-note spectra between the two modes is 902.95 Hz at different vapor-cell temperatures. …”
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Protein prediction for trait mapping in diverse populations. by Ryan Schubert, Elyse Geoffroy, Isabelle Gregga, Ashley J Mulford, Francois Aguet, Kristin Ardlie, Robert Gerszten, Clary Clish, David Van Den Berg, Kent D Taylor, Peter Durda, W Craig Johnson, Elaine Cornell, Xiuqing Guo, Yongmei Liu, Russell Tracy, Matthew Conomos, Tom Blackwell, George Papanicolaou, Tuuli Lappalainen, Anna V Mikhaylova, Timothy A Thornton, Michael H Cho, Christopher R Gignoux, Leslie Lange, Ethan Lange, Stephen S Rich, Jerome I Rotter, NHLBI TOPMed Consortium, Ani Manichaikul, Hae Kyung Im, Heather E Wheeler

“…Using GWAS summary statistics from the Population Architecture using Genomics and Epidemiology (PAGE) study, which comprises ∼50,000 Hispanic/Latinos, African Americans, Asians, Native Hawaiians, and Native Americans, we applied S-PrediXcan to perform PWAS for 28 complex traits. The most protein-trait associations were discovered, colocalized, and replicated in large independent GWAS using proteome prediction model training populations with similar ancestries to PAGE. …”
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Neonatal resuscitation skills acquisition among healthcare providers after Helping Babies Breathe simulation training using improved tools across two regions in Tanzania by Florence Salvatory Kalabamu, Vickfarajaeli Daudi, Robert Moshiro, Benjamin Kamala, Paschal Mdoe, Dunstan Bishanga, Hege Ersdal, Rose Mpembeni

“…Abstract Introduction Neonatal mortality is high in middle- and low-income countries, including Tanzania. Most of these deaths are preventable and linked to suboptimal quality of care. …”
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Prevalence and risk factors of intestinal parasitic infections among preschool and school-aged children in Egypt: a systematic review and meta-analysis by Ahmed Azzam, Heba Khaled

“…Meta-regression analysis revealed that the prevalence of at least one IPI remained consistent from 2009 to 2021. The most prevalent parasite was Entamoeba spp. (10.9%), followed by Giardia duodenalis (7.3%) and Enterobius vermicularis (4.9%). …”
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Frequency Analysis of Genetic Disorders Among Probable Carriers Identified Through Premarital Screening in Behshahr, 2023 by Mojgan Geran, Zahra Kashi, Mohammad Khademloo, Saman Soudmand arshad, Rogheye Khatoon Arab, Maryam Zarrinkamar

“…Results: According to the findings, the most frequently diagnosed conditions among the counselled couples, in descending order, were: thalassemia (12.7%), intellectual disability (4.9%), deafness and hearing loss (2.5%), Down syndrome (0.5%), blindness (0.3%), speech and kinship disorders (0.4%), and hydrocephalus, factor XI deficiency, low vision, celiac disease, juvenile arthritis, and movement disorders (0.8%). …”
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Glutathiones’ life in multi-cancers: especially their potential micropetides in liver hepatocellular carcinoma by Didi Ma, Zhenguo Wu, Mengying Zhang, Jian Mao, Wenqin Xu, Lan Jiang, Zuzhen Wang

“…Abstract Background Glutathione plays critical roles in detoxifying xenobiotics, cell signaling, cell death and the antioxidant defence in an emerging body of evidence, the most abundant intracellular low molecular weight thiol in tissues. …”
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A Comparative Analysis of Different Cartilage Grafts Used for Secondary Correction of Nasal Deformities in Cleft Lip and Palate Patients: A Case Series by Ankit Aggarwal, Raja Tiwari, R Manju, Komal Gupta, Maneesh Singhal

“…The underlying anatomic deformities mostly require replacement of the deficient framework with some form of cartilage grafts. …”
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Surgical treatment of corneal perforation by auto tissue: a clinical case by E. A. Ivachev

“…Over the 5-year period of treatment in an oncology hospital the patient received 48 courses of immunotherapy (the most recent session took place in June 2014). Starting from September 2014, the patient was treated for keratouveitis of both eyes. …”
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Comportamento de variáveis climáticas em sistemas de ventilação mínima para produção de pintos de corte Behavior of environmental variables on minimum ventilation systems for the p... by Irene Menegali, Ilda F. F. Tinoco, Cinara da C. S. Carvalho, Cecília de F. Souza, José H. Martins

“…<br>During the creation process of poultry, the initial or heating phase, is characterized as the most delicate period due to physiological immaturity of the birds. …”
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A cross-sectional survey of community health workers and their roles in Indiana by Michael Scanlon, Melissa R. Thomas, Qing Tang, Jasmine D. Gonzalvo, Yumary Ruiz, Margarita Hart, Jasmine Jackson, Debra K. Litzelman

“…Their scopes of practice varied but CHWs were most engaged in activities related to culturally relevant communication, care coordination, coaching, and social support. …”
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RFHP-CD: A Prompt-Driven Fine-Tuning Framework of Remote Sensing Foundation Model for Building and Cropland Change Detection by Guofang Wang, Yi Ma, Fangrong Zhou, Yifan Wang, Yijun Yan, Hao Geng

“…With the widespread adoption of foundation models in computer vision, remote sensing foundation models have emerged as a key approach for advancing intelligent Earth observation. However, most existing foundation models are pre-trained on natural images, leading to semantic gaps and task mismatches when transferred to remote sensing downstream tasks&#x2014;especially change detection, which requires fine-grained spatiotemporal modeling. …”
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The GWAS-MAP|ovis platform for aggregation and analysis of genome-wide association study results in sheep by A. V. Kirichenko, A. S. Zlobin, T. I. Shashkova, N. A. Volkova, B. S. Iolchiev, V. A. Bagirov, P. M. Borodin, L. С. Karssen, Y. A. Tsepilov, Y. S. Aulchenko

“…As part of this work, we focused on creating a platform similar to GWAS-MAP for working with the results of GWAS of sheep, since sheep breeding is one of the most important branches of agriculture. By analogy with the GWAS-MAP platform for storing, unifying and analyzing human GWAS, we have created the GWAS-MAP|ovis platform. …”
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Dynamic Changes in Tomato (<i>Solanum lycopersicum</i>) RNA m⁶A Modification During Seed Germination and Under Microgravity Conditions by Jiali Cui, Jiahui Zhao, Haiying Zhang, Jingyuan Li, Libo Jiang, Na Wang

“…Further exploration revealed that this promoting effect is correlated with m⁶A modification, manifested as enhanced expression of most m⁶A writer genes; increased expression levels of overall reader genes; altered expression trends of some m⁶A eraser genes, particularly <i>SlALKBH2</i>; and enhanced m⁶A modification levels. …”
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Multimodal tumor microenvironment signature of colorectal cancer for prediction prognosis and chemotherapy benefit by Wei Jiang, Kun Yang, Chanchan Xiao, Hongli Ji, Botao Yan, Shuhan Zhao, Biao Zhang, Jiaxin Cheng, Shuoyu Xu, Guangxing Wang, Zexi Lin, Jianping Lu, Gang Chen, Shuangmu Zhuo, Jun Yan

“…Shapley values identified the MTMSCRC as the most important predictor. Moreover, chemotherapy had no impact on prognosis in nomogram-predicted low-risk score patients but was associated with improved prognosis in medium and high-risk score patients. …”
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