Hemostatic dysfunction is increased in patients with hepatosplenic schistosomiasis mansoni and advanced periportal fibrosis. by Luiz Arthur Calheiros Leite, Adenor Almeida Pimenta Filho, Caíque Silveira Martins da Fonseca, Bianka Santana dos Santos, Rita de Cássia dos Santos Ferreira, Silvia Maria Lucena Montenegro, Edmundo Pessoa Lopes, Ana Lúcia Coutinho Domingues, James Stuart Owen, Vera Lúcia de Menezes Lima

“…In some patients, hepatic abnormalities lead to periportal fibrosis and result in the most severe clinical form, hepatosplenic schistosomiasis. …”
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A novel LncRNA risk model for disulfidptosis-related prognosis prediction and response to chemotherapy in acute myeloid leukemia by Yihong Wei, Hexiao Jia, Xiaodong Guo, Hailei Zhang, Xinyu Yang, Can Can, Na He, Hanyang Wu, Wancheng Liu, Daoxin Ma

“…Abstract Acute myeloid leukemia (AML), the most prevalent acute leukemia in adults, is characterized by its heterogeneity, which contributes to a poor prognosis and high recurrence rate. …”
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Exploring the best fit: A comparative analysis of AFINN, Textblob, VADER, and Pattern on Arabic reviews for optimal dictionary extraction by Shakeel Ahmad, Sheikh Muhammad Saqib, Asif Hassan Syed, Nashwan Alromema, Ali Kararay

“…The findings suggest that AFINN and VADER emerge as the most suitable dictionaries for effective sentiment analysis in Arabic text. …”
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Cardiovascular risk after total thyroidectomy in patients with differentiated thyroid carcinoma undergoing levothyroxine replacement monotherapy by Martina Pucci, Marilena Calzolaio, Francesco Ghezzi, Michela Iannotta, Maria Gifuni, Sabrina Ruberto, Francesca Crescenzo, Roberta Esposito, Bernadette Biondi

“…Considering these favorable outcomes, the most recent ATA guidelines recommend individualizing the degree of TSH suppression to balance the risks and benefits of LT4 therapy based on the aggressiveness of the disease. …”
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Modern trends in diagnostics and prediction of results of anti-vascular endothelial growth factor therapy of pigment epithelial detachment in neovascular agerelated macular degener... by E. V. Kozina, S. N. Sakhnov, V. V. Myasnikova, E. V. Bykova, L. E. Aksenova

“…The pigment epithelium tear of 3–4th degrees can lead to a sharp decrease in visual acuity.Most retrospective studies confi rm the absence of a proven correlation between anatomical and functional outcomes in the treatment of pigment epithelial detachment in cases of maintaining the integrity of the pigment epithelium monolayer, and therefore the main attention of researchers is focused on studying the morphological features of pigment epithelial detachment during therapy with angiogenesis inhibitors. …”
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Disparities in employment outcomes among critical care graduates with different training backgrounds by Greg J. Eisinger, Patrick J. Sylvester, Dheeraj Duggineni, David P. Way, Jing Peng, Jiang Ma, Jennifer W. McCallister, Matthew C. Exline

“…Fifty-nine participants were included, reflecting a low rate of return. Most worked in urban areas (76.6%) at academic hospitals (81.7%). …”
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Digital health interventions on chronic obstructive pulmonary disease: a scoping review by WANG Wenya, SHI Lanjun, HU Jing, LIAO Xing

“…The providers of DHIs were mainly clinical medical staff, and the intervention guidance content was mainly about medication (73.64%) and rehabilitation exercises (62.73%). Most literature supported that DHIs improved laboratory indicators, self- efficacy, exercise tolerance, compliance, disease progression and cognitive function in COPD patients, while there was controversy over psychological status and health economic assessment.Conclusion DHIs have potential development as a disease management tool for COPD patients. …”
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The Role of Mitochondrial Energy Metabolism in the Mechanism of Exercise Improving Depression by Yuwei Liu, Chenghao Zhong, Yuxin Yang, Jianbo Hu, Xiaoyan Yi, Jiating Huang, Haonan Li, Xiaojie Liu, Ke Xue, Xianghe Chen

“…Depression is the most disabling neuropsychiatric disorder, but its exact mechanisms remain unclear. …”
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Sexually Transmitted Infections in A Tertiary Hospital of Kathmandu: A Retrospective Study by Sushil Paudel, Niraj Parajuli, Sudip Dahal, Sudarshan Paudel

“…Males were having significantly more premarital or extramarital sexual exposures as compared to females (p<0.001). The most common presentation was condyloma acuminata in 84(53.5%) patients. …”
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Gene network inference and biochemical assessment delineates GPCR pathways and CREB targets in small intestinal neuroendocrine neoplasia. by Ignat Drozdov, Bernhard Svejda, Bjorn I Gustafsson, Shrikant Mane, Roswitha Pfragner, Mark Kidd, Irvin M Modlin

“…In vitro studies, in a model NET cell system, confirmed that transcriptional effects are signaled through the cAMP/PKA/pCREB signaling pathway and that a SI NET cell line was most sensitive to a D(2) and 5-HT(2) receptor agonist BIM-53061.…”
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Human Mesenchymal Stem Cells Derived from the Placenta and Chorion Suppress the Proliferation while Enhancing the Migration of Human Breast Cancer Cells by Sarawut Sirithammajak, Sirikul Manochantr, Chairat Tantrawatpan, Duangrat Tantikanlayaporn, Pakpoom Kheolamai

“…Background. Breast cancer is the most frequently diagnosed malignancy among women, resulting from abnormal proliferation of mammary epithelial cells. …”
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Facial filling with polymethylmethacrylate in patients with acquired immunodeficiency syndrome by Walter Henrique Martins, Karina Viviani de Oliveira Pessôa, Marcos Alberto Martins, Mariliza Henrique da Silva, Gerson Vilhena Pereira Filho, Luiz Carlos de Abreu

“…Human immunodeficiency virus was diagnosed 11.5 years prior on average, with 10-year average use of HAART and 3.8-year average time of facial lipoatrophy. Most of the patients used stavudine and/or efavirenz. …”
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Fruit and vegetable consumption among Brazilian adults: trends from 2008 to 2023 by Izabella Paula Araújo Veiga, Thais Cristina Marquezine Caldeira, Marcela Mello Soares, Taciana Maia de Sousa, Luiza Eunice Sá da Silva, Rafael Moreira Claro

“…Prais-Winsten regression models were used to identify trends in the entire (2008-2023), initial (2008-2014) and most recent (2015-2023) periods. Regular and recommended consumption remained stable from 2008 to 2023. …”
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Detectability of Emission from Exoplanet Outflows Calculated by pyTPCI, a New 1D Radiation-hydrodynamic Code by Riley Rosener, Michael Zhang, Jacob L. Bean

“…We calculate the eclipse depths and signal-to-noise ratios (SNRs) of these lines for a 10 m class telescope with a high-resolution spectrograph, taking into account appropriate line broadening mechanisms. We show that the most detectable spectral lines tend to be the 589 nm Na i doublet and the 1083 nm metastable helium triplet. …”
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Effects of biotopes on the quality of cherry wood (Prunus avium) in Tunisia by Jdaidi Nouri, Selmi Houcine, Abbes Chaabane

“…The rate of decay varies with age, so most infected trees are old (diameter at breast height &amp;gt; 30 cm). …”
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Problems of follicular thyroid carcinoma diagnostics by S. E. Titov, S. A. Lukyanov, S. V. Sergiyko, Yu. A. Veryaskina, T. E. Ilyina, E. S. Kozorezov, S. L. Vorobyov

“…Sequencing revealed the 5 most distinct microRNAs between follicular cancer and follicular adenoma: miR-625, miR-323a, let-7a, let-7c and miR-574. …”
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Clinical management of constipation – the role of physical activity - systematic review by Sebastian Flanczewski, Wiktoria Gajek-Flanczewska, Agata Walczak, Jakub Wirkijowski, Wiktoria Niegowska, Paulina Woźniak, Kajetan Kidacki, Agata Wiklińska, Martyna Śliwińska, Katarzyna Wójtowicz, Aleksandra Jaroń, Karolina Piątkowska

“…Although evidence supports the role of physical activity in managing constipation, further research is needed to clarify the most effective exercise regimens and their integration with dietary and lifestyle modifications.    …”
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Impact of the Timing of Enzyme Replacement Therapy Initiation and Cognitive Impairment Status on Outcomes for Patients with Mucopolysaccharidosis II (MPS II) in the United States:... by Karen S. Yee, David Alexanderian, Yidie Feng, Xiaowei Ren, Bernd Schweikert, Olulade Ayodele

“…Patients with CI generally experienced greater symptom burden and higher HRU than those without CI, with the most notable differences documented for communication and toileting delays. …”
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Laboratory indicators of the disorders of immune-endocrine balance in children with acute respiratory viral infection during post-COVID period by L. A. Alekseeva, A. A. Zhirkov, T. V. Bessonova, I. V. Babachenko, N. S. Tian, G. F. Zheleznikova

“…During post-COVID period children after acute respiratory viral infections had identified immuneendocrine dysfunctions giving evidence to inhibition of the synthesis of hormones of adrenal gland cortex and thyroid system; synthesis of most cytokines; insufficient activation of congenital immunity that is likely to occur due to COVID-19 that proves the necessity of immune-corrective therapy.…”
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“They Say the Water Is Perfectly Safe but…”: A Mixed‐Methods Participatory Study of Factors Influencing Trust in Tap Water Safety in a Great Lakes City by Colleen M. O’Brien, Vidya Venkataramanan, Clare Tallon Ruen, Erin McCotter, Anika Mittu, Revika Singh, Liliana Hernandez Gonzalez, Aaron I. Packman, William M. Miller, Sera L. Young

“…In collaboration with a local environmental organization and a university, we conducted community‐based participatory research that included surveys (n = 756) and in‐depth interviews (n = 52) with a convenience sample of residents. Most (92.6%) respondents reported primarily consuming tap water. 81.2% of survey respondents (n = 749) thought their tap water was safer than or as safe as bottled water. …”
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