Notoginsenoside R1 attenuates tendinopathy through inhibiting inflammation and matrix metalloproteinases expression by Qingxin Han, Junying Wu, Yan Li, Yi Tong, Xiaohua Liu, Xiaoqing Hu, Lei Zhang

“…In vivo studies revealed that NGR1 mitigates the pathological response of tendinopathy induced by collagenase, exhibiting a dose-dependent efficacy, with the 8 μM concentration yielding the most favorable outcomes. RNA sequencing analyses of tenocytes indicated that NGR1 potentially treats tendinopathy by modulating the synthesis of collagen and matrix metalloproteinases, as well as attenuating LPS-induced inflammatory responses. …”
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Pengaruh Parsial dan Simultan Variabel Bebas terhadap Kepuasan Pelanggan Transportasi Online Kota Palembang by Kurniati Kurniati

“…Abstract Online-based business services are growing in meeting the needs of people's lives. The most important goal of this business is to create customer satisfaction. …”
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Virtual Health Care in Hospital-at-Home Models for Patients With Acute Infections: A Scoping Review by Maria Normand Larsen, MD, Tatjana Sandreva Dreisig, MD, Maja Kjær Rasmussen, MSc, Anders N.Ø. Schultz, MD, Thyge Lynghøj Nielsen, MD, PhD, Thea K. Fischer, MD, DMSc

“…Hybrid models provided broader treatment options, but many studies lacked detailed intervention descriptions, complicating implementation and meta-analyses. Most studies evaluated patient outcomes, with limited attention to health care staff and relatives. …”
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Advancing County-Level Potato Cultivation Area Extraction: A Novel Approach Utilizing Multi-Source Remote Sensing Imagery and the Shapley Additive Explanations–Sequential Forward S... by Qiao Li, Xueliang Fu, Honghui Li, Hao Zhou

“…The Random Forest (RF) model, utilizing the full feature set, emerged as the most accurate, achieving a precision rate of 0.97 and a kappa value of 0.94. …”
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Access and benefit sharing biological materials for machines: Artificial intelligence, machine learning and deep learning by Charles Lawson, Elizabeth Englezos, Michelle Rourke

“…We then posit two issues for ABS: (1) negotiating the ownership status to use the input data with each data owner for training, testing (and verifying) and using the models (although a further complication here is that most data is without an owner because it is already open and free as a public domain without intellectual property restrictions); and (2) following the data per se through the AI models (explainability). …”
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Kolmogorov Capacity with Overlap by Anshuka Rangi, Massimo Franceschetti

“…This notion of capacity generalizes the Kolmogorov <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mi>ϵ</mi></semantics></math></inline-formula>-capacity to packing sets of overlap at most <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mi>δ</mi></semantics></math></inline-formula> and is a variation of a previous definition proposed by one of the authors. …”
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Pediatric Genetic Dystonias: Current Diagnostic Approaches and Treatment Options by Graziana Ceraolo, Giulia Spoto, Carla Consoli, Elena Modafferi, Gabriella Di Rosa, Antonio Gennaro Nicotera

“…Among these, <i>TOR1A</i>, <i>SGCE</i>, and <i>KMT2B</i> are the most frequently reported in pediatric forms. Diagnosis is challenging due to the wide clinical and genetic variability. …”
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In-field nucleic acid testing for porcine epidemic diarrhea virus with lateral flow immunoassay by Wencong Chen, Jiahao Chen, Danni Ye, Xueyan Ai, Jiayi Luo, Chenxi Fang, Meihua Xiang, Maopeng Wang

“…Early virus detection is a more effective disease management strategy for pigs. Unfortunately, most methods rely heavily on skilled personnel and sophisticated equipment, which is not ideal in scenarios requiring cost reduction and efficiency. …”
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Implementing interventions that include mentoring components with young people with foster care experience: Lessons learned from the field by Amy M. Salazar, Sara S. Spiers, Deborah G. Fabiyi, Jenna Thompson

“…The research question was, “What are lessons learned regarding how to most successfully engage in (a) mentor recruitment, (b) mentor training, (c) mentor-mentee matching, (d) pair oversight, (e) group activities, and (f) closing relationships, for organizations implementing FHE?” …”
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Morphological and Genetic Diversity of Mangrove Species Ceriops tagal (Perr.) C.B. Rob. Around Java Island by Dhuta Sukmarani, Elly Proklamasiningsih, Agus Hery Susanto, Erwin Riyanto Ardli, Jefri Permadi, Flandrianto Sih Palimirmo

“…The UPGMA dendogram was used to analyze the morphological similarity, and multidimensional unfolding analysis was used to determine which character most determined the grouping. Mega X software was used to analyze genetic variation using the neighbor-joining approach, while Arlequin 3.5 software was used to estimate genetic variation within and among populations. …”
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Antimicrobial resistance patterns and virulence determinants of clinical enterococcus isolates in Pakistan by J. Ullah, A. Aziz, A. Ullah, I. Ullah, A. Jabbar, M. Umair, M. Ullah, H. Ullah, M. Ullah, Ihsan Ali

“…The VRE isolates carried antimicrobial resistance and virulence-related genes, and vanA, B, D phenotypes were the most common among VRE isolates.…”
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Anticodon sequence determines the impact of mistranslating tRNAAla variants by Ecaterina Cozma, Megha Rao, Madison Dusick, Julie Genereaux, Ricard A. Rodriguez-Mias, Judit Villén, Christopher J. Brandl, Matthew D. Berg

“…Variants with G/C-rich anticodons resulted in larger growth deficits than A/U-rich variants. In most instances, synonymous anticodon variants impact growth differently, with anticodons containing U at base 34 being the least impactful. …”
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Pregnancy-Associated Changes in Pharmacokinetics: A Systematic Review. by Gali Pariente, Tom Leibson, Alexandra Carls, Thomasin Adams-Webber, Shinya Ito, Gideon Koren

“…<h4>Background</h4>Women are commonly prescribed a variety of medications during pregnancy. As most organ systems are affected by the substantial anatomical and physiological changes that occur during pregnancy, it is expected that pharmacokinetics (PK) (absorption, distribution, metabolism, and excretion of drugs) would also be affected in ways that may necessitate changes in dosing schedules. …”
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Current Phylogeographic Structure of <i>Anemone altaica</i> (Ranunculaceae) on the Khamar-Daban Ridge Reflects Quaternary Climate Change in Baikal Siberia by Marina Protopopova, Polina Nelyubina, Vasiliy Pavlichenko

“…Estimation of isolation by distance effect, spatial autocorrelation analysis, PCoA, and AMOVA indicated a clear spatial genetic structure for <i>A. altaica</i> on the Khamar-Daban Ridge. The most reliable geographical model suggests that during periods of Pleistocene cooling, <i>A. altaica</i> persisted in at least six microrefugia within the ridge. …”
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Means of forming political loyalty of the younger generation of Russian emigrants to the Japanese occupation authorities in the territory of Northeast China (Manchuria) by E. S. Babkina, Yu. S. Pestushko, S. I. Yakimova

“…The chronological scope of this study is defined as 1931–1945 and covers one of the most complex and controversial periods in the history of the Asia-Pacific region. …”
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rRNA loss induced by rifampicin addition in Escherichia coli reflects extraction artifacts rather than in vivo degradation by Mathilde Burck, Sébastien Nouaille, Agamemnon J. Carpousis, Muriel Cocaign-Bousquet, Laurence Girbal

“…RNA 27, 946–958 (2021) recently presented experimental evidence that rifampicin treatment leads to a 50% decrease in total RNA levels due to degradation of 23S and 16S rRNA. Since most mRNA decay in E. coli is initiated by RNase E, which also contributes to the degradation of 23S and 16S rRNA, this suggests that mRNA and rRNA may compete for RNase E in vivo, potentially affecting cell physiology. …”
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Development of Swallowing Function in Infants with Oral Feeding Difficulties by Changhun Han, Jaeho Shin, Ga Won Jeon

“…Swallowing dysfunction was improved in most infants after they became matured. They showed different time and rate of maturation with the help of rehabilitation through swallow therapy and dietary modification with thickened formula. …”
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Deconstructing resuscitation training for healthcare providers: a protocol for a component network meta-analysis by Toshi A Furukawa, Orestis Efthimiou, Adam Cheng, Maria Petropoulou, Kee-Hsin Chen, Ferika Indarwati, Defi Efendi, Dessie Wanda, Hazrina Adelia, Eva Oktaviani, Qurrata Aini, Bejo Utomo, Nana Rochana

“…It is essential to identify the most effective of these components and their combinations, to measure the corresponding effect size and to understand which participant groups may enjoy the greatest advantage.Methods and analysis We will systematically search 12 databases and two clinical trial registries for randomised controlled trials (RCTs) that examine different resuscitation training methods from inception to April 2025. …”
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The influence of weather conditions during an autumn period on the development of basic wreckers and diseases of agrocenosis of winter wheat in Forest-Steppe zone by L. Parminska, N. Havryliuk

“…The increase in air temperature and a sufficient amount of precipitation in the autumn period leads to dissemination of sowing the most widespread wreckers and affection of plants by diseases. …”
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Biologically oriented synthesis of medicines (BIODS) based on heterylpoxid 2,5- disubstituted 1,3,4-oxadiazoles (Part 1) by Yu. V. Karpenko, O. I. Panasenko, Ye. H. Knysh

“…The review article firstly summarizes the literature on the chemistry of hetero derivatives of 2,5 disubstituted 1,3,4-oxadiazoles as important synthetic substrates and precursors for biologically oriented synthesis. The most classical methods of obtaining, which are the intramolecular dehydration of 1,2-diacylhydrazines, the interaction of hydrazyl carboxylic acid hydrazides with carbon disulfide and the formation of the oxadiazole nucleus by microwave synthesis are considered. …”
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