Pharmacotherapy of hepatitis D: the current and the future by George Sarin Zacharia, Anu Jacob

“…The past decade witnessed an advanced understanding of HDV virology and pathogenesis, which led to the development of multiple specific and targeted therapeutic agents, most notably the HDV viral entry inhibitor, bulevirtide, and the prenylation inhibitor, lonafarnib. …”
Get full text

Resolving the APN controversy in PEDV infection: Comparative kinetic characterization through single-virus tracking. by Da An, Yan Li, Yi Pei, Yong-Hao Ma, Fei Yao, Yongzhi Feng, Yanke Shan, Fei Liu

“…Aminopeptidase N (APN) plays multiple roles in various physiological processes, with its function as a viral receptor in several coronaviruses being one of the most prominent. However, the role of porcine APN (pAPN) in porcine epidemic diarrhea virus (PEDV) has remained controversial. …”
Get full text

Beliefs of Health Care Providers, Lay Health Care Providers and Lay Persons in Nigeria Regarding Hypertension. A Systematic Mixed Studies Review. by James Tosin Akinlua, Richard Meakin, Philip Fadahunsi, Nick Freemantle

“…<h4>Results</h4>The search yielded a total of 3,794 hits from which 16 relevant studies (2 qualitative, 11 quantitative and 3 mixed methods studies) met the inclusion criteria for the review. Overall, most health care providers (HCPs) believe that stress is a major cause of hypertension. …”
Get full text

Optimization of an EMU train carbody by the value of the natural bending frequency by R. V. Guchinsky

“…When mass is limited, it is possible to choose designs that are characterized by the greatest overall body rigidity and are the most optimal in terms of manufacturability. By limiting the values of natural vibration frequency, it is possible to choose a body structure with the lowest metal mass. …”
Get full text

Clinical manifestations of human brucellosis: a systematic review and meta-analysis. by Anna S Dean, Lisa Crump, Helena Greter, Jan Hattendorf, Esther Schelling, Jakob Zinsstag

“…<h4>Conclusions</h4>This systematic review adds to the understanding of the global burden of brucellosis, one of the most common zoonoses worldwide. The severe, debilitating, and chronic impact of brucellosis is highlighted. …”
Get full text

Analysis of pharmacy organisation staff awareness of pharmacovigilance by R. I. Yagudina, O. L. Listova, A. R. Umerova, K. A. Kopeyka

“…The influence of education, work experience and job position on the awareness of professionals was established. Most respondents recognize the need to report adverse drug reactions (ADRs) occurring when taking a medicine, but in practice the level of reporting remains low.Conclusion. …”
Get full text

Contagious order as a risk factor for liver fibrosis progression in co-infection with human immunodeficiency virus, hepatitis B and C viruses by E. P. Feoktistova, D. Yu. Konstantinov, E. S. Malova, I. P. Balmasova

“…In the risk group, the most effective antiretroviral therapy was a combination of reverse transcriptase inhibitors, HIV protease inhibitors, and direct antiviral (anti-HCV) drugs. …”
Get full text

Characterization of Complete Mitochondrial Genome and Phylogeny of Three Echeneidae Species by Fenglin Wang, Chenghao Jia, Tianxiang Gao, Xingle Guo, Xiumei Zhang

“…The findings revealed that the mitochondrial genome lengths of the three species were 16,611 bp, 16,648 bp, and 16,623 bp, respectively, containing 13 protein-coding genes (PCGs), 22 transfer RNA genes (tRNAs), two ribosomal RNA genes (rRNAs), and a D-loop region. Most PCGs utilized ATG as the initiation codon, while only <i>cox I</i> used the GTG as the initiation codon. …”
Get full text

Using the ADAPT guidance to culturally adapt a brief intervention to reduce alcohol use among injury patients in Tanzania. by Catherine A Staton, Armand Zimmerman, Msafiri Pesambili, Ashley J Phillips, Anna Tupetz, Joao Vitor Perez de Souza, Judith Boshe, Michael H Pantalon, Monica Swahn, Blandina T Mmbaga, Joao Ricardo Nickenig Vissoci

“…Brief negotiational interventions (BNIs) in emergency departments (EDs) effectively reduce alcohol intake and re-injury rates. However, most BNIs are developed in high-income countries, with limited evidence of their effectiveness in LMICs. …”
Get full text

Sustainable Absorbent Pads from Polybutylene Adipate Terephthalate/Thermoplastic Starch Films Combined with Hairy Basil (<i>Ocimum basilicum</i>) Powder to Enhance Meat Shelf Life by Fuengnapha Khunta, Korakot Charoensri, Rineta Pertiwi Nurhadi, Nattinee Bumbudsanpharoke, Pontree Itkor, Youn-Suk Lee, Athip Boonsiriwit

“…The PBAT:TPS ratio of 70:30 (PB7T3) was the most suitable in terms of mechanical properties and water permeation. …”
Get full text

Optimization Design Method of Pipe-Insulating Joints Based on Surrogate Model and Genetic Algorithm by Chen Guo, Zheng Yang, Jianbo Dong, Yanchao Yue, Linjun Tian, Ping Ma

“…This study analyzed an insulating joint under the most unfavorable conditions to identify the component of the maximum stress in the insulating joint, which is the right flange. …”
Get full text

Inflammatory imbalance and activation deficits in T cells of myasthenia gravis patients revealed by proteomic profiling by Amol K. Bhandage, Anna Rostedt Punga

“…Despite growing interest in the immunological etiology of MG, few functional studies have addressed the role of T cells, and most existing work has focused on quantifying immune cell subsets using flow cytometry. …”
Get full text

Single-cell chromatin landscapes associated with the burnt skin healing process in rats by Tao Wang, Bolin Zhu, Jianyu Lu, Xinya Guo, Ruikang Li, Yue Yuan, Junjie Chen, Xi Dai, Shuai Liu, Jiaxin Du, Xun Xu, Huan Liu, Xiaoyu Wei, Runzhi Huang, Shizhao Ji

“…Abstract Thermal injuries represent one of the most severe forms of trauma to the human body, with a high annual incidence of burn victims globally. …”
Get full text

Potential sustained production of polyhydroxyalkanoate copolymers using cyanobacteria microbiomes by Lin Sun, Joan García, Eva Gonzalez-Flo

“…Abstract The copolymer poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) is considered one of the most promising PHA candidates for bioplastics production, exhibiting superior physical properties than the homopolymer poly(3-hydroxybutyrate) (PHB). …”
Get full text

Mapping Temperate Grassland Dynamics in China Inner Mongolia (1980s–2010s) Using Multi-Source Data and Deep Neural Network by Xuefeng Xu, Jiakui Tang, Na Zhang, Anan Zhang, Wuhua Wang, Qiang Sun

“…This study demonstrates the potential of DNN for long-term grassland mapping and provides the most comprehensive classification maps of Inner Mongolia grasslands to date, which are invaluable for grassland research and conservation efforts in the area.…”
Get full text

KRID: A Large-Scale Nationwide Korean Road Infrastructure Dataset for Comprehensive Road Facility Recognition by Hyeongbok Kim, Eunbi Kim, Sanghoon Ahn, Beomjin Kim, Sung Jin Kim, Tae Kyung Sung, Lingling Zhao, Xiaohong Su, Gilmu Dong

“…Comprehensive datasets are crucial for developing advanced AI solutions in road infrastructure, yet most existing resources focus narrowly on vehicles or a limited set of object categories. …”
Get full text

Risk factors for repetition of self-harm: a systematic review of prospective hospital-based studies. by Celine Larkin, Zelda Di Blasi, Ella Arensman

“…<h4>Conclusions</h4>Many risk factors for repetition of self-harm match risk factors for initiation of self-harm, but the most consistent evidence for increased risk of repetition comes from long-standing psychosocial vulnerabilities, rather than characteristics of an index episode. …”
Get full text

Liver transplantation from 73-year-old cadaveric donor by M. N. Kornilov, M. G. Minina, I. A. Miloserdov, D. N. Kruglov, R. S. Chaikin, A. G. Malakhov, S. I. Zubenko, S. V. Gautier

“…Deceased donor organs are the prevailing source in most transplantation centers. However, there is an organ shortage because of the increasing number of patients in need of transplantation. …”
Get full text

NIRS and machine learning algorithms as a non-invasive technique to discriminate and classify cooked broiler and duck meat by Kamrunnahar Khan Bristy, Dip Ghosh, Md. Abul Hashem

“…Logistic Regression and SVM have emerged as the most efficacious methods, attaining high accuracy and balanced precision and recall. …”
Get full text

Serological and virulence factors analysis of Escherichia coli isolates causing post-weaning diarrhea in intensive pig farms by JIANG Zhong-qi, WANG Na, FANG Wei-huan, SUN Jian-hua, LI Hong-zhou

“…The toxins and adhesins F18 and K88 are the most important virulence factors involved.…”
Get full text