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71081
Mixture of common and uncommon pathways and genes regulating primary and secondary immunoglobulin M responses in chickens
Published 2025-09-01“…Moreover, RNF220, ATP6V0B, KIF2C, and CDC20 genes were involved in most of the pathways related to both traits.…”
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71082
Informed consent in genetic and genomic studies in Sub-Saharan Africa: a systematic review of bioethical issues
Published 2025-07-01“…Returning results had potential advantages in building trust between participants and the research team; however, the most appropriate way to return results is under discussion. …”
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71083
Improving Soil Health and Potato Productivity through Lime and Nitrogen Management in Northern Ethiopia
Published 2025-03-01“…However, liming had no significant effect on most yield parameters except for the weight of medium and small tubers. …”
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71084
The Molecular Breeding of Different Ecotype <i>Japonica</i> Varieties Resistant to Rice Blast with High Genome Collinearity
Published 2025-06-01“…The Yangtze River Delta (YRD) is one of the most important <i>japonica</i> rice planting areas in China. …”
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71085
Similarity of immune-associated markers in COVID-19 and Kawasaki disease: analyses from bioinformatics and machine learning
Published 2025-05-01“…Abstract Background Infection by the SARS-CoV-2 virus can cause coronavirus disease 2019 (COVID-19) and can also exacerbate the symptoms of Kawasaki disease (KD), an acute vasculitis that mostly affects children. This study used bioinformatics and machine learning to examine similarities in the molecular pathogenesis of COVID-19 and KD. …”
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71086
Unraveling the potential: mRNA therapeutics in oncology
Published 2025-08-01“…They are focused on malignancies like melanoma, non-small cell lung cancer, prostate cancer, or pancreatic ductal adenocarcinoma, one of the most challenging cancers. While many trials are in early phases, some have advanced to phase 3 and have shown promising results in both safety and efficacy. …”
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71087
Indoor High Precision Three-Dimensional Positioning System Based on Visible Light Communication Using Particle Swarm Optimization
Published 2017-01-01“…But unfortunately, in the matter of algorithm complexity and positioning accuracy, most existing VLC-based systems fail to deliver satisfactory performance. …”
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71088
Which factors related to apical radiolucency may influence its radiographic detection? A study using CBCT as reference standard
Published 2021-08-01“…For PAN, apical radiolucency is most often detected in single-rooted teeth.…”
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71089
Perioperative outcomes among older surgical patients with multimorbidity: a longitudinal study from Ethiopia
Published 2025-08-01“…Among all geriatric patients, 130 (14.87%) had hypertension, 34 (3.89%) had diabetes mellitus, and 29 (3.32%) had cancer. The most common multimorbidity combination was hypertension and diabetes (18 cases). …”
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71090
Folate-based binuclear Mn(II) chelates with 2,2’-bipyridine/1,10-phenanthroline as targeted anticancer agents for colon cancer cells
Published 2025-07-01“…The prepared chelates exhibit significant cytotoxic effects against folate receptor-positive cell lines, with colon cancer HCT116 cells being the most affected. Furthermore, the anticancer mechanism of action on the HCT116 cell line was investigated by analyzing the wound healing, cell cycle profile, expression of pro-apoptotic and anti-apoptotic proteins, as well as examining the morphological changes in treated cells. …”
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71091
Sensitivity of Fungal Microbe Aspergillus niger to New Synthetic Analogs of Natural Isocoumarin Antibiotics
Published 2024-03-01“…From the results presented in the present work, it follows that the investigated field cultures of Aspergillus niger are most sensitive to antimycotic drugs belonging to N-methylnaphthylmethylamine derivatives and polyene antimycotics — terbinafine (MMSC = 0–2 µg/cm3) and nystatin (MMSC = 4–8 µg/cm3, IE-1 = 1.69, IE-K2 = 1.51), which have a pronounced mycocidal effect. …”
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71092
Green solvents and enzymes combined with advanced extraction techniques for the recovery of bioactive carotenoids and extractable/non-extractable polyphenols from grapefruit peels
Published 2025-08-01“…UAE (15 min, 30 % amplitude) followed by EAE (70 °C, 40 min) and MAE-NaDES using choline chloride:lactic acid (1:2, 50 % water, 50 °C, 6 min) yielded the most bioactive NEPs. HPLC-DAD-QTOF-MS analysis allowed to identified 19 polyphenols in both extracts, highlighting naringin as the majority, particularly in UAE-EAE extract. …”
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71093
Genome-wide characterization and expression analysis of the CONSTANS-like gene family of Juglans mandshurica Maxim
Published 2025-04-01“…The promoters of genes in this family contain stress-related cis-acting elements, hormone-related response elements, and other elements associated with growth and development. Notably, the most prominent elements are the light-responsive elements, suggesting that genes in this family are predominantly expressed in leaves. …”
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71094
LUCC-based carbon emission simulation under multiple-scenarios in the Guangdong-Hong Kong-Macao Greater Bay Area
Published 2025-08-01“…Key findings: The moderate development scenario achieves the most balanced land-use changes, whereas other scenarios exhibit extreme shifts in specific land types. …”
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71095
Not just semantics: CO2 fertilization can be a disturbance leading to worldwide forest degradation
Published 2025-05-01“…This demonstrates that even the most remote forests in the world have been altered by human action via CO2 fertilization, and the responsibility for their integrity must be shared globally.…”
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71096
Radiation Therapy in Combination with Magnetotherapy for Painful Bone Metastases in Patients with Breast Cancer
Published 2020-05-01“…Analysis of the patients’ general status according to the Karnofsky performance scale index showed that the pretreatment index ranged from 50 to 70 points in most patients of the control group. After radiation therapy, the indices improved, rising up to 80 points in one-third of patients. …”
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71097
Integrated Transcriptomics and Metabolomics Provide Insight into Degeneration-Related Molecular Mechanisms of <i>Morchella importuna</i> During Repeated Subculturing
Published 2025-05-01“…Total flavonoid content was markedly higher in NM than in DG, with most flavonoid compounds showing reduced levels in degenerated strains. …”
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71098
Magnetic resonance imaging versus cone beam computed tomography in diagnosis of periapical pathosis – A systematic review
Published 2021-12-01“…From those, 19 articles were finally selected that included original research studies, case reports, and case series and were included for systematic review. Most of the studies included in this review suggested that the combined use of CBCT and MRI is needed for a better and more precise diagnosis of complex periapical pathoses. …”
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71099
Detection of Psychomotor Retardation in Youth Depression: A Machine Learning Approach to Kinematic Analysis of Handwriting
Published 2025-07-01“…The feature selection process revealed that velocity-related features were most effective in distinguishing patients with depression from controls, expectedly reflecting a slowdown in psychomotor functioning among the patients. …”
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71100
Signature-based small molecule screening identifies cytosine arabinoside as an EWS/FLI modulator in Ewing sarcoma.
Published 2007-04-01“…Despite the identification of tumor-specific somatic mutations, most cancer therapy still utilizes nonspecific, cytotoxic drugs. …”
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