OPTIMIZATION OF PHARMACEUTICAL CARE FOR JUVENILE RHEUMATOID ARTHRITIS AT THE REGIONAL LEVEL by A. A. Skripko, L. N. Geller, G. G. Radnaev, Т. V. Hadanova

“…According to the content analysis of the reports of the regional Ministry of Health on preferential drug provision of handicapped children, both in hospital and at outpatient treatment stage, the pharmacotherapy schemes including Adalimumab, Abatacept, Infl iximab, Tocilizumab, Etanercept are most in demand.Conclusion. The study of the organization of GEBP pharmacotherapy, the expert assessment carried out by the doctors, the results of the marketing analysis of the regional pharmaceutical market made it possible to substantiate and propose a rational assortment portfolio of this group of medicines for treatment of various JRA options, taking into account the price component in the Irkutsk region. …”
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The Behaviour of Contaflex Soft Contact Lens Material During Hydration by Joseph Towler, Markus Zaplachinski, Roberto Montiel, Nikhil Murari, Christine Deng, Rimmo Lego, Arwa Fathy, Ahmed Abass

“…Power simulations revealed deviations beyond ISO tolerance limits in most materials, particularly those with higher water-content. …”
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Velocity Model Construction and Time-to-Depth Conversion of a Vintage Seismic Reflection Profile for Improving the Constraints on a Subsurface Geological Model: An Example from the... by Aasiya Qadir, Nicolò Chizzini, Mariagiada Maiorana, Andrea Artoni, Luigi Torelli, Attilio Sulli

“…This study provides a new subsurface velocity field that can be applied, or taken into account, to most parts of the Sicily Channel when structural and stratigraphic interpretations are carried out at specific sites and where uncertainties in subsurface geological model exist (e.g., in the present study, the volcanic bodies in the Pantelleria Graben and Lampedusa High).…”
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Alfacalcidol in clinical practice: focus on the efficacy and safety of the Russian generic drug by N. V. Toroptsova, M. V. Kozyreva, O. V. Dobrovolskaya

“…The most important factors that determine the risk of fractures are not only the presence of osteoporosis (OP), but also the risk of falls. …”
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A data-driven analysis of emergency first responder education on substance use and stress management across demographic and professional backgrounds by Francine R. Vega, Audrey Lopez, Vicky Beakley, A. Sarah Cohen, Tiffany Champagne-Langabeer

“…The Substance Use Disorder in the First Responder Workforce and Coping with Anxiety courses were the most popular and recruited a total of 897 and 337 participants, respectively. …”
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Comparative effectiveness and complications of intravenous ceftriaxone compared with oral doxycycline in Lyme meningitis in children: a multicentre prospective cohort study by Lise E Nigrovic, Thomas H Chun, John J Halperin, Sara E Vargas, Aisling R Caffrey, Jonathan A Race, Ulrike Ott, Brynna L Morrison, Bethany J Fuller, John M VanBuren, Pedi Lyme Net

“…Introduction Lyme disease is the most common vectorborne disease in the Northern hemisphere with more than 400 000 new cases in the USA annually. …”
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Drivers of nutrient intakes from fisheries in French Polynesia by Mark Hamilton, Eva Maire, Charlotte Monteil, Vainehu Vane, Nicholas A. J. Graham, Victor Brun, James P. W. Robinson, Joachim Claudet, Valeriano Parravicini, Christina C. Hicks

“…People ate a higher diversity of reef fish in Raiatea, however nutrient intakes from fish were higher in Moorea. Most people ate more fish than meat on both islands, however fish consumption declined over generations. …”
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Effect of roasting time and method on physicochemical and functional properties of roasted maize grain (Asharo) by Masresha Gebeyehu Ewunetu, Zemene Tadege Woldie, Aynadis Molla Asemu

“…Roasting was performed on conditioned maize grains for the preparation of asharo. Although most parts of Ethiopia prepare tella from roasted various products using traditional methods that affect the physicochemical and functional properties of the products. …”
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Comprehensive Characterization of Mesenchymal Stem Cells from Human Placenta and Fetal Membrane and Their Response to Osteoactivin Stimulation by C. M. Raynaud, M. Maleki, R. Lis, B. Ahmed, I. Al-Azwani, J. Malek, F. F. Safadi, A. Rafii

“…Mesenchymal stem cells (MSCs) are the most promising seed cells for cell therapy and can be isolated from various sources of human adult tissues such as bone marrow (BM-MSC) and adipose tissue. …”
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Comparison of the effects of eight weeks of traditional resistance training and TRX on oxidative and antioxidant indicators in women with type 2 diabetes by Mohsen Akbarpour, Safoora Sabagheyan rad, Narjes Chamani

“…Background and Purpose: Type 2 diabetes is one of the most common metabolic diseases known in the world and is the main cause of death in many countries, affecting many people every year. …”
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Mathematical modelling and time series clustering of Mpox outbreak: A comparative study of the top 10 affected countries and implications for future outbreak management by Mark-Daniels Tamakloe, Ametus Kuuwill, Ibrahim Osumanu, Helina Siripi

“…This study presents a comparative epidemiological analysis of the ten countries most affected by Mpox, integrating mathematical modelling with time series clustering, the first of its kind to analyze the 2022 WHO Mpox data. …”
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The Impact of Advanced Maternal Age on Neonatal Outcome in Preterm Births before 34 Weeks by Daniel Tairy, Ohad Gluck, Yakira Izaik, Jacob Bar, Eran Weiner, Giulia Barda

“…Background: In recent years a trend towards childbearing at older maternal age is evident. Most of the current literature investigated the association between advanced maternal age and neonatal outcome at term. …”
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Radiographic cephalometry analysis of head posture and craniofacial morphology in oral breathing children by Vukićević Vladanka, Pavlović Jasna, Vujačić Amila, Martinović Brankica, Kostić Mirjana, Staletović Danijela

“…Oral breathing children have pronounced retroflexion of the head in relation to the cervical spine compared to nasal breathing children, and the most prominent characteristics of the craniofacial morphology of skeletal jaw relationship of class II and increased facial convexity.…”
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Mechanistic Insights and Anti-cancer Activity of 2H-benzo[b][1,4]oxazin-3(4H)-one Linked 1,2,3-Triazoles in Human Cancer Cells by Qingying Liu, Qingying Liu, Xixi Hou, Mingyue Tian, Baoyu He, Jingjing Guo, Yajie Guo, Jianxue Yang

“…Cell viability assays revealed that these compounds exhibited the most potent activity against A549 cells. Among them, compounds 14b and 14c demonstrated the strongest inhibitory effects, with IC50 values of 7.59 ± 0.31 μM and 18.52 ± 0.59 μM, respectively. …”
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Modern classification and molecular-genetic aspects of osteogenesis imperfecta by A. R. Zaripova, R. I. Khusainova

“…Osteogenesis imperfecta (imperfect osteogenesis in the Russian literature) is the most common hereditary form of bone fragility, it is a genetically and clinically heterogeneous disease with a wide range of clinical severity, often leading to disability from early childhood. …”
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Spatially distributed gradient-based calibration and parametric sensitivity of a spatialized hydrological model over 235 French catchments by Pierre-André Garambois, François Colleoni, Ngo Nghi Truyen Huynh, Ahmad Akhtari, Ngoc Bao Nguyen, Apolline El-Baz, Maxime Jay-Allemand, Pierre Javelle

“…Parameter analysis reveals stable and interpretable patterns: water balance parameters, especially production capacity (cp) and water exchange (kexc), are most sensitive, while routing parameters are less so. …”
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Barriers and facilitators to cervical cancer screening in the Eastern Mediterranean Region: a systematic review by Ramin Rezapour, Mohammad Saadati, Hassan Sarsour, Lamia Mahmoud, Moradali Zareipour, Soma Khezri

“…Abstract Background Cervical cancer is the sixth most common cancer among women in Eastern Mediterranean Region. …”
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Hydro chemical assessment of groundwater quality using pollution index, quality indexes, fuzzy-GIS, graphical and multivariate techniques from a mining region of Eastern India by Suvankar Naskar, Debashis Mandal, Brototi Biswas, Chaitali Mukherjee

“…The region has a dominant anion type of chloride and bicarbonate type. 17.70% of the region falls under “Most Moderate to Worst hazardous Zone” as per GWHI, though NSFWQI indicates that the entire region’s groundwater is unsafe to drink, except for a few pockets. …”
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Features of the Clinical Course and Prognosis of Severe Traumatic Brain Injury Outcomes by Y. B. Vasilyeva, A. E. Talypov, M. V. Sinkin, S. S. Petrikov

“…Traumatic brain injury (TBI) is one of the most important contemporary health issues. According to the World Health Organization, TBI is one of three leading causes of death in the world. …”
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Overexpression of WDFY2 inhibits prostate cancer cell growth and migration via inactivation of Akt pathway by Jianqing Wang, Xu Chen, Shijun Tong, Huihui Zhou, Jianliang Sun, Yuancheng Gou, Fei Wu, Jimeng Hu, Jianfeng Xu, Guanxiong Ding

“…Prostate cancer is the most commonly diagnosed malignancy and is the second leading deadly reason among male cancer. …”
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