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70721
Impact of Honeybee Venom Melittin on Cell Viability of Different Prostate Cancer Lineages
Published 2022-07-01“…With PC-3 cells, a 0.1 μg/mL concentration suppressed proliferation significantly to 46.15 %, while melittin at a 10 μg/mL dose had a cytolytic effect on most cells (4.27 % viability). LNCaP cells experienced the lowest toxicity at 10 μg/mL melittin compared to PC-3 and DU145 lineages. …”
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70722
Flavonoids and anxiety: decoding their role in brain function and pathophysiology
Published 2025-09-01“…Anxiety disorder ranks among the most common mental health issues globally, thereby emphasizing the pressing necessity for the development of safer and more effective treatment alternatives. …”
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70723
Recent Developments in Individual Difference Research to Inform the Adoption of AI Technology
Published 2025-02-01“…Artificial intelligence (AI) technology has become one of the most frequently discussed subjects in the development of technology in recent years. …”
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70724
A deep learning model with machine vision system for recognizing type of the food during the food consumption
Published 2025-08-01“…The augmented datasets were then processed through nine popular deep learning architectures, identifying ResNet50, EfficientNetB5, B6, and B7 as the most effective architectures. An essential step involved updating hyperparameters, including image size, batch size, learning rate, and optimizer settings, to enhance convergence rates and accuracy. …”
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70725
Plasma proteomic signatures of dual cognitive and mobility decline in older adultsResearch in context
Published 2025-08-01“…Longitudinally, only dual decline showed significant changes in 75 proteins, with PGP9.5 showing the most alteration (p-FDR < 0.05), implicated in synaptic function, proteostasis, and regulation of amyloid precursor protein and amyloid β protein. …”
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70726
PROSPECTS FOR THE CUSTOMS UNION IN TERMS OF MODERN THEORIES OF REGIONAL INTEGRATION
Published 2017-01-01“…Leading the trend of world development is globalization, which covers all areas of public life, including economic, and national economies poses more challenges, fi rst and foremost – ensuring competitiveness on a global scale, fi nd their own niche in the international division of labor.The development of the global trading system is characterized by two interrelated trends – the expansion of economic openness and the formation of trade unions, to ensure the most favorable terms of trade between the participating countries. …”
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70727
The use and the frequency of Arabic loan words in the Turkish language
Published 2025-01-01“…After these language purist movements, the Turkish language was free from loan words, but still there are those words that are deeply rooted in the Turkish language corpus, and these words are mostly Arabic. The use of Arabic loan words is most effective in the domain of legal and administrative language register, given that in these segments no linguistic puritanism was executed. …”
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70728
Fusarium blight of common buckwheat in Primorsky krai
Published 2022-05-01“…Common buckwheat is one of the most important cereal and melliferous crops being in demand both in Russia and overseas. …”
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70729
Nursing Errors in Iranian Nurses: A Mixed Study
Published 2025-06-01“…The average scores for the most prevalent causes of errors were highest in the organizational dimension (3.8 ± 1.01). …”
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70730
Assessment of a Patient Dose Monitoring System for Average Glandular Dose (AGD) Estimate in Mammography
Published 2025-03-01“…Results showed that the AGD values displayed by the systems were generally consistent with those calculated using the Dance method, but discrepancies emerged when applying the Boone method, especially when using estimated glandular composition. Most mammograms fell within acceptable and achievable dose limits according to European guidelines, though a small percentage exceeded these thresholds. …”
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70731
THE DEVELOPMENT OF MEMBRANOUS PATHOLOGY OF HEPATOCYTES THE INFLUENCE OF INTOXICATION
Published 2018-10-01“…At a dose 1/10 LD50 we observed the most significant increase in this indicator on the 10th day of the experiment - at 265%, and at a dose 1/100 LD50 – on the 20th day an average of 234%. …”
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70732
From Molecules to Medicines: The Role of AI-Driven Drug Discovery Against Alzheimer’s Disease and Other Neurological Disorders
Published 2025-07-01“…A detailed literature review was performed to gather evidence regarding the most recent AI tools for drug discovery against AD, Parkinson’s disease (PD), multiple sclerosis (MLS), and epilepsy, focusing on biological markers, early diagnoses, and drug discovery using various databases like PubMed, Web of Science, Google Scholar, Scopus, and ScienceDirect to collect relevant literature. …”
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70733
Sgr A* Spin and Mass Estimates through the Detection of Multiple Extremely Large Mass Ratio Inspirals
Published 2025-01-01“…Theoretical estimates suggest the presence of approximately 10 XMRIs emitting detectable GWs, making them some of the most promising candidates for space-based GW detectors. …”
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70734
Identification of a potential interspecies reassortant rotavirus G and avastrovirus 2 co-infection from black-headed gull (Chroicocephalus ridibundus) in Hungary.
Published 2025-01-01“…The black-headed gull is the most common nesting gull species in Hungary. Based on the lifestyle and feeding habits of the black-headed gull, which is highly adapted to the human environment, they can be carriers and spreaders of potential human and other animal pathogens. …”
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70735
Current Perspective on the Treatment of the Novel Coronavirus Infection COVID-19
Published 2025-06-01“…COVID-19, caused by the novel coronavirus SARS-CoV-2, has emerged as one of the most serious global health challenges in recent decades. …”
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70736
Guideline appraisal with AGREE II: Systematic review of the current evidence on how users handle the 2 overall assessments.
Published 2017-01-01“…<h4>Introduction</h4>The Appraisal of Guidelines for Research & Evaluation (AGREE) II instrument is the most commonly used guideline appraisal tool. It includes 23 appraisal criteria (items) organized within 6 domains and 2 overall assessments (1. overall guideline quality; 2. recommendation for use). …”
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70737
Exploring Treatment Strategies for Secondary Knee Osteonecrosis Using Core Decompression with Augmentation Techniques: Case Report
Published 2025-07-01“…The femoral head is the most common area, followed by the knee. Knee osteonecrosis is further divided into primary, secondary and postarthroscopic, based on etiology. …”
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70738
The smart city concept as a method of building urban resilience to threats: Evidence from Poland
Published 2025-07-01“…Conclusions Sustainability and resilience are among the most critical challenges in ensuring city security. …”
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70739
Myrtenol’s Effectiveness against Hospital-Acquired Methicillin-Resistant Staphylococcus aureus: Targeting Antibiofilm and Antivirulence Properties
Published 2024-01-01“…Combinations of myrtenol with most tested antibiotics exhibited synergistic effects exceeding 60%. …”
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70740
Development of automatic insect-tracking robot system for measuring local activity changes in free walking
Published 2025-06-01“…Further information-theoretic analysis revealed that the moth might be moving in the direction most likely to lead to odor detection, depending on the timing of its olfactory reception. …”
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