Intraoperative Course of Left Ventricular Diastolic Strain in Surgical Valve Replacement for Severe Aortic Valve Stenosis by Katharina Seuthe, Eva Gerwin, Parwis Rahmanian, Bernd W. Böttiger, Deepak Borde, Jakob Labus

“…LV relaxation and filling improved during the intraoperative course of AVR as measured by diastolic strain, while most conventional grading algorithms were not able to detect these alterations.…”
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Surface morphology of worn out tool used for friction stir welding of aluminium plates by field emission scanning electron microscope (FESEM) by Ratnesh Kumar, Somnath Chattopadhyaya, Madhulika Srivastava, Saurabh Dewangan

“…The results highlight that the tool shoulder surface endures the most significant wear due to direct contact with the workpiece material. …”
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Optimizing Patient Access to Orphan Medicinal Products: Lessons from Central and Eastern Europe by Tomasz Kluszczynski, Bertalan Nemeth, Magdalena Władysiuk, Marcin Czech, Maria Kamusheva, Nicolae Fotin, Sandra Rose, Tomáš Doležal, Rok Hren

“…The analysis identified sub-optimal OMP access across most CEE countries, marked by prolonged delays and lower reimbursement rates compared to Western Europe, with Slovenia and Czechia as notable exceptions. …”
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Guaranteed False Data Injection Attack Without Physical Model by Chenhan Xiao, Napoleon Costilla-Enriquez, Yang Weng

“…Additionally, we integrate a Generative Adversarial Network (GAN) to explore the measurement manifold and induce the most significant state changes, enhancing the impact of the attack. …”
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Investigation of the effects of walnut shell wood particles on the mechanical properties of injection molded wood‐ polyethylene‐polycarbonate composites by Rasool R. K. Al‐Arkawazi, Taher Azdast, Rezgar Hasanzadeh

“…The findings indicate that 0 wt % PC, 20 wt % walnut shell and the particle size ranging from (1.5 to 1) mm is the most effective compound among all the conditions. …”
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Cyclicality and Economic Growth Dynamics: Business Cycles’ Typologization, Dating, and Matching with Oil Price Fluctuations by Habiba Bouguerroumi, Yacine Belarbi

“…Thus, this asymmetry is also substantiated by the Excess Cumulated Movements Index, which has a negative value of -0.47 % for contractions, in contrast to a positive but modest value of 0.05 % for expansions. Finally, one of the most significant findings of this study is the high sensitivity of economic cyclicality to fluctuations in hydrocarbon market prices. …”
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IrSPI, a tick serine protease inhibitor involved in tick feeding and Bartonella henselae infection. by Xiang Ye Liu, Jose de la Fuente, Martine Cote, Ruth C Galindo, Sara Moutailler, Muriel Vayssier-Taussat, Sarah I Bonnet

“…Ixodes ricinus is the most widespread and abundant tick in Europe, frequently bites humans, and is the vector of several pathogens including those responsible for Lyme disease, Tick-Borne Encephalitis, anaplasmosis, babesiosis and bartonellosis. …”
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Acute toxicity and "structure-action" dependence of 4-(R-benzylidenamino)-5-methyl-4H-1,2,4-triazoles 3-tion by T. V. Kravchenko, Ye. S. Pruglo, O. I. Panasenko, E. G. Knysh

“…The least toxic compound among the studied 4-(R-benzylidenamino)-5-methyl-4H-1,2,4-triazoles-3-thiones was compound 1 with an index of 840 mg/kg, which contains 4-methoxybenzilidene substituent on N4-nitrogen atom and the most toxic was compound 5, which has 4-brombenzilidene substituent at the same prosition (LD50 – 284 mg/kg). …”
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The Drivers of Hydrologic Behavior in Brazil: Insights From a Catchment Classification by André Almagro, Antônio Alves Meira Neto, Noemi Vergopolan, Tirthankar Roy, Peter A. Troch, Paulo Tarso S. Oliveira

“…Then, we used a recursive feature elimination using the random forest technique to assess the most influential catchment attributes to the hydrological signatures. …”
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The follow-up of patients with celiac disease by Marco Di Tola, Hetty J. Bontkes, Juan Irure-Ventura, Marcos López-Hoyos, Nicola Bizzaro

“…According to current criteria, a proper diagnosis of CD requires an initial phase consisting of clinical case identification and serological screening that, over time, has increased in importance. In most adults and in selected children, the diagnosis is subsequently defined by histological evidence of intestinal damage as a confirmatory test, which usually returns to normal after a suitable period of a gluten-free diet (GFD). …”
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Programmed cell death-driven remodeling of the melanoma microenvironment enables prognostic stratification and therapeutic prediction by Bo Hu, Shengnan Chai, Xuan Li, Qiang Zhang, Mei Jin, Long Zhang

“…Immune infiltration, immunogenomic correlations, and immunotherapy responses were further evaluated using ESTIMATE, CIBERSORT, TMB, IPS, and external ICB-treated cohorts.ResultsAmong all cell types, melanoma cells exhibited the highest PCD activation, with disulfidptosis, immunogenic cell death (ICD), and autosis being the most prominent. High PCD activity was linked to advanced clinical stage, lymphatic metastasis, and poor prognosis. …”
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Collective impact school–university partnerships in teacher education: intentionally designed clinical practice experiences by Lin Rudder, Drew Polly, Kristien Zenkov, Madelyn W. Colonnese

“…Originality/value – Our article demonstrates how SUPs and clinical experiences can be structured using the collective impact framework to be most beneficial and impactful for all partners and PK-12 students. …”
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Identifying Key Biomarkers Related to Immune Response in the Progression of Diabetic Kidney Disease: Mendelian Randomization Combined With Comprehensive Transcriptomics and Single-... by Hu M, Deng Y, Bai Y, Zhang J, Shen X, Shen L, Zhou L

“…Miao Hu, Yi Deng, Yujie Bai, Jiayan Zhang, Xiahong Shen, Lei Shen, Ling Zhou Department of Nephrology, The First Affiliated Hospital of Soochow University, Suzhou, People’s Republic of ChinaCorrespondence: Ling Zhou, Email zl66060@163.comBackground: Renal failure related death caused by diabetic kidney disease (DKD) is an inevitable outcome for most patients. This study aimed to identify the critical genes involved in the onset and progression of DKD and to explore potential therapeutic targets of DKD.Methods: We conducted a batch of protein quantitative trait loci (pQTL) Mendelian randomization analysis to obtain a group of proteins with causal relationships with DKD and then identified key proteins through colocalization analysis to determine correlations between variant proteins and disease outcomes. …”
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Assessment of geotechnical behavior of gypseous soil under leaching effect using machine learning by Saif M. Hassan Al-Riahi, Nur Irfah Mohd Pauzi, Mohammed Y. Fattah, Hasan Ali Abbas

“…Feature importance analysis identified gypsum content, leaching time, and total dissolved solids (TDS) as the most influential variables. This study introduces a robust, data-driven approach for demonstrating the highest accuracy and robustness in predicting soil behavior, bridging experimental testing with advanced predictive modeling. …”
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Development of an Injury Burden Prediction Model in Professional Baseball Pitchers by Garrett Bullock, Charles Thigpen, Gary Collins, Nigel Arden, Thomas Noonan, Michael Kissenberth, Ellen Shanley

“…The inclusion of both modifiable and non-modifiable factors into a comprehensive injury burden model provides the most accurate prediction of days lost in professional pitchers…”
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DETERMINATION OF PHYTOCHEMICAL CONSTITUENTS AND ANTIMICROBIAL ACTIVITY OF ANOGEISSUS LEIOCARPUS EXTRACTS by Kefas Ishaya Ambair, James Hamuel Doughari, Joel Uyi Ewansiha, Musa Sale Pukuma

“…Antimicrobial activity showed root bark acetone extract to be the most active with diameter of zone of inhibition of 25.0+1.41 against Staphylococcus aureus, a minimum inhibitory concentration (MIC) of 0.313±0.00 mg/ml against Pseudomonas aeruginosa and Klebsiella pneumonia and a minimum bactericidal concentration (MBC) of 0.625±0.00 mg/ml against Pseudomonas aeruginosa and Klebsiella pneumonia. …”
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Traditional and molecular methods for diagnosing bacterial meningitis in Erbil city, Iraq by Niga Othman Hamaameen, Adel Kamal Khider

“…Bacterial culture findings were positive in 7% of CSF samples and just one positive among blood samples. The most common pathogens found by cultural characteristics and VITEK 2 Compact System were Staphylococcus sciuri in two cases  2%, Staphylococcus xylosus in one case  1%, Escherichia coli in two instances  2%, Enterococcus casseliflavus and Micrococcus luteus each in one case  1%. …”
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A Study on the Mechanical Properties and Bursting Liability of Coal-Rock Composites with Seam Partings by Dong Xu, Mingshi Gao, Yongliang He, Xin Yu

“…Geological tectonic movements, as well as complex and varying coal-forming conditions, have led to the formation of rock partings in most coal seams. Consequently, the coal in coal-rock composites is characterised by different mechanical properties than those of pure coal. …”
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Self-efficacy profile in daily activities: Children at risk and with developmental coordination disorder by G.C. Nobre, N.C. Valentini, M.H.S. Ramalho, R.F. Sartori

“…The discriminate analysis showed that perceived self-efficacy in leisure activities was the variable that most contributed to the discrimination of the groups. …”
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Quantum algorithms and complexity in healthcare applications: a systematic review with machine learning-optimized analysis by Agostino Marengo, Vito Santamato

“…., references to biomedical applications versus blockchain-based security frameworks), offering transparency into the literature-driven categorization, with the latter showing the most significant contributions to topic assignment (ranging from −0.133 to +0.128). …”
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