Exploratory Data Analysis of the In Vitro Effects of Novel Hydrazide-Hydrazone Antioxidants in the Context of In Silico Predictors by Yordan Yordanov, Virginia Tzankova, Denitsa Stefanova, Maya Georgieva, Diana Tzankova

“…HCPC differentiated <b>5a</b> as mostly neuroprotective, <b>5</b> and <b>5d</b> as hepatoprotective radical scavengers, <b>5g</b> with higher docking affinity to 5-lipoxygenase (5-LOX) and myeloperoxidase (MPO) and <b>5b</b>, <b>5c</b> and <b>5f</b> as having less H-bond donors and variable in vitro activity. …”
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Early Diagnosis of Knee Osteoarthritis With a Natural Language Processing–Driven Approach Based on Clinician Notes: Development and Validation Study by Narathip Thanyakunsajja, Kulsawasd Jitkajornwanich, Shan Xu, Donghee Shin, Pattama Charoenporn

“…Moreover, the diagnosis results can vary among physicians depending on their expertise. Previous studies mostly focused on using approaches, such as those involving artificial intelligence, to automatically detect knee OA through such data. …”
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BRAVA: A randomized controlled trial of a brief group intervention for youth with suicidal ideation and their caregivers by Allison Kennedy, Clare Gray, Nicole Sheridan, Leigh Dunn, Jayme Stewart, Stéphanie Drouin, Hannah Elliott, Ademola Adeponle, Nicholas Barrowman, Ewa Sucha, Mario Cappelli, Mark L. Norris, Mona Jabbour, Paula Cloutier

“…Adolescents were on average 14.6 years old, mostly female (64%), and of European racial heritage (44%). …”
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CompaRative Safety Analysis of Innovator and BioSimilar Ranibizumab in Chorioretinal Vascular Diseases - The CRsIBS Study by Chakraborty D, Sinha TK, Sinha S, Biswas RK, Maiti A, Boral S, Das A, Mandal S, Bhattacharya R, Dan S, Rungta D

“…Ocular adverse events were mostly mild, with similar rates of transient blurring, subconjunctival hemorrhage, and ocular pain. …”
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Shooting Mechanisms in Nature: A Systematic Review. by Aimée Sakes, Marleen van der Wiel, Paul W J Henselmans, Johan L van Leeuwen, Dimitra Dodou, Paul Breedveld

“…The mass-specific power output is also scale dependent, with smaller mechanisms being able to release the energy for shooting faster than larger mechanisms, whereas the mass-specific work delivered by the shooting mechanism is mostly independent of the scale of the shooting mechanism. …”
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Reflective Processes and Social Orientation at Different Stages of Professionalisation (on the Example of Preparation for Medical Activity) by G. V. Manuilov, G. G. Gorelova, E. A. Rylskaya, S. V. Morozova, N. N. Vasyagina

“…The identified ways of respondents’ social orientation demonstrate the contradictory nature of relations to oneself and to others; and such relations were mostly expressed at the beginning of training. Along with the fear of being rejected, manifested at an unconscious level, the respondents took the conscious decisions to preserve own individuality and to maintain the distance with other people. …”
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Integrated analysis of transcriptomics and metabolomics and high-throughput amplicon sequencing reveals the synergistic effects of secondary metabolites and rhizosphere microbiota... by Li Yingtao, Li Qiaofeng, Wang Lijuan, Qi Shuyun, Jiang Zhou, Zhang Wenping, Zhang Aili

“…Microbiome data indicated a significant enrichment of Actinobacteria at the genus level in the rhizosphere soil of diseased samples (DS) compared to healthy samples (HS) while the mostly beneficial growth-promoting bacterial groups were found in DR root endophytes, including Enterobacter, Pseudomonas, Klebsiella, Stenotrophomonas, and Bacillus. …”
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Knowledge and Attitude Towards the Care For Self-harming Adolescents and the Related Factors in Emergency Department Nurses From Northern Iran by Fereshteh Foroughizad, Yasaman Yaghobi, Farzaneh Sheikholeslami, Elnaz Faraji-Nesfechi, Ehsan KazemnezhadLeili

“…Nurses’ attitudes were mostly positive, and the total ADSHQ score was 3.59±0.28. …”
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Dry Eye Cross-Sectional Study – Philippines: Comparison with the Asia Dry Eye Society Criteria and OCULUS Keratograph 5M Findings by Ruben Lim Bon Siong, MD, Bobbie Marie Santos, MD, Keshia Duyongco-Lenon, MD, Jessica Marie Abaño, MD, Reynaldo Santos, MD, Ivo John Dualan, MD

“…Patients with DED were mostly female (66.3%). Compared to normal participants, patients with DED were older (42.7 ± 14.6 years) and had higher OSDI scores (28.6 ± 21.0). …”
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Understanding food choices and promoting healthier food options among online food delivery service users in Australia: a qualitative study by Adyya Gupta, Kathryn Backholer, Catherine E. Huggins, Rebecca Bennett, Gloria K.W. Leung, Anna Peeters

“…Results Thirty Australian adults participated in the study. Participants were mostly women (80%) with a mean age of 28 years and living in metropolitan Melbourne. 85% had completed higher education, 20% lived with children < 18 years of age and > 80% used OFDS 2–5 times per week. …”
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Surface water quality assessment for drinking and pollution source characterization: A water quality index, GIS approach, and performance evaluation utilizing machine learning anal... by Abhijeet Das

“…Various water quality indices (WQIs), implementing machine learning’s models including ANN, SVM, DT, RF, LOR), and KNN, jointly revealed that 36.36 % of samples reflects excellent to good water quality, while 63.64 % renders water quality status as unsuitable, which were mostly found in the central, south-eastern, and northeastern areas. …”
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Dilution of broiler breeder diets with oat hulls prolongs feeding but does not affect central control of appetite by Laura M. Dixon, Sarah Brocklehurst, Joe Hills, Simone Foister, Peter W. Wilson, Angus M.A. Reid, Sarah Caughey, Victoria Sandilands, Tim Boswell, Ian C. Dunn, Rick B. D'Eath

“…However, restricted birds were willing to cross in only 7.3% to 12.5% of tests. Mostly birds stayed on the start platform, where AL birds sat more than other treatments and OH40% birds reduced walking relative to R birds (P = 0.016). …”
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Dose-response of tomato fruit yield to far-red fraction in supplementary lighting by Elena Vincenzi, Aron Moehn, Emmanouil Katsadas, Sana Karbor, Esther de Beer, Frank Millenaar, Leo F.M. Marcelis, Ep Heuvelink

“…Fruit yield increases under additional FR were mostly associated with increased plant dry weight, with a small yet significant increase in the fraction of dry matter partitioned to the fruits. …”
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Adherence at 2 years with distribution of essential medicines at no charge: The CLEAN Meds randomized clinical trial. by Nav Persaud, Michael Bedard, Andrew Boozary, Richard H Glazier, Tara Gomes, Stephen W Hwang, Peter Juni, Michael R Law, Muhammad Mamdani, Braden Manns, Danielle Martin, Steven G Morgan, Paul Oh, Andrew D Pinto, Baiju R Shah, Frank Sullivan, Norman Umali, Kevin E Thorpe, Karen Tu, Andreas Laupacis, Carefully seLected and Easily Accessible at No Charge Medications (CLEAN Meds) study team

“…The trial population was mostly female (56%), younger than 65 years (83%), white (66%), and had a low income from wages as the primary source (56%). …”
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State of the Dotcom-era accounting information systems (AIS) faculty and implications for the artificial intelligence (AI)-era by Akhilesh Chandra, Charles F. Malone

“…Findings: We find that doctoral programs supplying AIS faculty are public institutions and mostly in the southern states. AIS faculty are (i) less in private institutions; (ii) less in professor ranks; (iii) proportionately more with a PhD and certified public accountant (CPA) credentials; and (iv) similar in gender split, vis-à-vis all accounting faculty. …”
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Metabolic engineering of Komagataella phaffii for enhanced 3-hydroxypropionic acid (3-HP) production from methanol by Sílvia Àvila-Cabré, Joan Albiol, Pau Ferrer

“…Co-overexpression of PYC2 and the lactate permeases ESBP6 and JEN1 genes led to a 55% improvement in 3-HP titer and product yield in methanol deep-well plate cultures compared to the reference strain, mostly due to Esbp6 activity, proving its effectiveness as a 3-HP transporter. …”
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Anthropometric Measurements in Predicting Haemorrhagic Stroke Among Bangladeshi Population: The MAGPIE Study by Ranjan R, Adhikary D, Ken-Dror G, Yusuf MA, Moureen A, Hakim M, Sharma P

“…Redoy Ranjan,1,2 Dipannita Adhikary,1 Gie Ken-Dror,1 Md Abdullah Yusuf,3 Adneen Moureen,4 Maliha Hakim,5 Pankaj Sharma1,6 1Department of Biological Sciences, Royal Holloway University of London, London, UK; 2Department of Cardiac Surgery, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh; 3Department of Microbiology, National Institute of Neurosciences and Hospital, Dhaka, Bangladesh; 4Tuberculosis New Technologies and Diagnostics, USAID’s, Dhaka, Bangladesh; 5Department of Neurology, National Institute of Neurosciences and Hospital, Dhaka, Bangladesh; 6Department of Clinical Neuroscience, Imperial College Healthcare NHS Trust, London, UKCorrespondence: Pankaj Sharma, Department of Biological Sciences, Royal Holloway University of London, London, UK, Email pankaj.sharma@rhul.ac.ukBackground: Anthropometric measurements used to predict cardiovascular disease vary worldwide but are mostly derived from those of Caucasian ancestry. We sought to undertake such measurements in the little studied Bangladeshi population.Methods: The MAGPIE (Multidimensional Approach of Genotype and Phenotype in Stroke Etiology) study is a Bangladeshi stroke case–control study that recruited nationwide between January 2022 and June 2024. …”
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Hypertension and cognitive impairment among older persons in rural Northern Uganda: a cross-sectional study by Joel Oyugi, Jonathan Izudi, Francis Bajunirwe

“…Available data on this association is mostly from resource-rich settings and has been understudied in resource-limited settings especially rural areas where the majority of older persons live. …”
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Effects of types of toothpastes (whitening versus regular) and brands of silicone aesthetic ligatures on discoloration of elastomeric ligatures applied to mandibular central and la... by Majid Aryannejad, Hooman Ghazi Oskouei, Marzieh Mazhari, Mehrnaz Moradinezhad

“…Both ligature brands showed a level of discoloration deemed clinically unacceptable (E > 3.3), regardless of the toothpaste used. Discolorations were mostly due to severe changes in ∆B parameter (yellowness) compared to ∆L or ∆A (P = 0.000). …”
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The efficacy and safety of biologics for patients with severe asthma: an umbrella review of systematic reviews and meta-analyses by Qionghua Xiao, Qionghua Xiao, Yuanming Huang, Yuanming Huang, Bingyu Xue, Bingyu Xue, Minghang Wang

“…However, the methodological quality of included SR/MAs was mostly low or critically low, suggesting that we need to be cautious when interpreting the results of this study. …”
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