Road Transport and Urban Mobility Greenhouse Gas Emissions Factor for Air Pollution Modeling in Burkina Faso by Issaka Abdou Razakou Kiribou, Tiga Neya, Bernard Nana, Kehinde Ogunjobi, Tizane Daho, Y․ Woro Gounkaou, Faith Mawia Muema, Dejene W. Sintayehu

“…With an average emission of 1.89 mol/m2, the satellite tropospheric nitrogen dioxide concentration is mostly affecting the Central Business Division (CBD) of Ouagadougou City. …”
Get full text

Rates of colorectal cancer diagnosis and mortality in people with severe mental illness: results from Australia’s National Bowel Cancer Screening Programme by S. Kisely, K. Spilsbury, C. Bull, S. Jordan, B.J. Kendall, D. Siskind, G. Sara, M. Protani, D. Lawrence

“…Abstract Aims Studies show that people with severe mental illness (SMI) have a greater risk of dying from colorectal cancer (CRC). These studies mostly predate the introduction of national bowel cancer screening programmes (NBCSPs) and it is unknown if these have reduced disparity in CRC-related mortality for people with SMI. …”
Get full text

Nedosiran Safety and Efficacy in PH1: Interim Analysis of PHYOX3 by Jaap Groothoff, Anne-Laure Sellier-Leclerc, Lisa Deesker, Justine Bacchetta, Gesa Schalk, Burkhard Tönshoff, Graham Lipkin, Sandrine Lemoine, Thomas Bowman, Jing Zhou, Bernd Hoppe

“…All participants experienced ≥1 adverse event (AE), mostly mild or moderate in severity (primarily, injection site events). …”
Get full text

The influence of microwave-assisted osmotic dehydration in coconut meat preservation technique by Mahfujul Alam, Mipahur Jannat, Nayon Datta, Mir Meahadi Hasan, Asraful Alam, Md. Ashrafuzzaman Zahid, Md. Shakir Moazzem, Mohammad Mainuddin Molla, Mrityunjoy Biswas

“…Based on multivariate statistical analyses, the quality of coconut meat is mostly influenced by thermal processing and storage period.There was a considerable rise in the bioactive compounds and a significant decrease in the moisture content observed during storage. …”
Get full text

Patient perceptions, motivations and barriers to treatment adherence in hypertension: results of a questionnaire-based survey in five European countries by Michel Burnier, Michel Azizi, Julien Magne, Aleksander Prejbisz, Vitoria Cunha, Pankaj Gupta, Jan Vaclavik, Jorie Versmissen, Véronique Cornelissen, Maria Dorobantu, Giovambattista Desideri, Alexandre Persu, Sverre E. Kjeldsen, Reinhold Kreutz, Thomas Weber

“…Non-adherence is underreported by patients; hence it remains mostly unrecognised.…”
Get full text

Iron status in women of reproductive age in Morocco by Bouchra Mekkaoui, Nabila Auajjar, Abdelhakim Yahyane, Laila El Ammari, Salwa Labzizi, Anouar Talouizte, Hasnae Gamih, Hassan Aguenaou, Kaoutar Benjeddou, Khalid El Kari

“…Background Women of reproductive age (WRA) are one of the vulnerable population mostly impacted by anemia and iron deficiency (ID) worldwide. …”
Get full text

The role of neotectonics and climate variability in the Pleistocene-to-Holocene hydrological evolution of the Fuente de Piedra playa lake (southern Iberian Peninsula) by A. Jiménez-Bonilla, L. Martegani, L. Martegani, M. Rodríguez-Rodríguez, F. Gázquez, F. Gázquez, M. Díaz-Azpíroz, S. Martos, K. Reicherter, I. Expósito

“…Consequently, the FdP flooded surface mostly remained constant and in equilibrium with climate variables and its watershed along its lifespan. …”
Get full text

Perceived stress and family adaptability in head and neck cancer patients receiving radiotherapy: the chain-mediated effect of social support and family resilience by Xiaoru Li, Xiaoru Li, Xiaoru Li, Yu Zhu, Yu Zhu, Yu Zhu, Hongwei Wan, Hongwei Wan, Hongwei Wan

“…Bootstrap methods to analyze independent and chained mediation effects between variables.ResultsThe research participants had a mean age of 43.63 ± 12.78 years, were mostly male (61.7%), married (85.8%), had a university education (51.6%), were uninsured (50.9%), had ear, nose, and throat tumors (56.3%), and had an illness duration of 1-6 months (43.4%). …”
Get full text

Descriptive Epidemiology and Mortality Risk Factors of COVID-19 Outbreak in Delta State, Nigeria, March – August 2020 by Adaora Rosemary Ejikeme, Bola Biliaminu Lawal, Shalom Ogbonna, Ehimario Igumbor, Mildred Okowa, Ivie Airefetalor, Daniel Otoh, Angela Okocha-Ejeko, Onyinyechi Emefiene, Ann Ojimba, Henry Uguru-Ekechi, Rhoda Atteh, Nkiruka Obiazor, Chukwuma David Umeokonkwo, Muhammad Shakir Balogun, Oladipupo Ipadeola, Abdulhakeem Abayomi Olorukooba, Aboyowa Edukugho, Bolaji Ahmed, Oladipo Ogunbode

“…Conclusion: Males in the youthful age-group were mostly affected. Independent predictors of mortality were being elderly or symptomatic at time of testing. …”
Get full text

Stereotactic radiosurgery alone for patients with 16 or more brain metastases: Retrospective single-institution analysis by Michael T. Milano, Sara Hardy, Dandan Zheng, Terris Igwe, Daniel Huang, Amit K. Chowdhry, Jihyung Yoon, Tyler M. Schmidt, Kevin A. Walter, Hyunuk Jung, Yuwei Zhou, Kenneth Y. Usuki

“…Twenty-eight underwent 3-fraction SRS (mostly 8–9 Gy per fraction), and 1 underwent single-fraction SRS (20 Gy). …”
Get full text

Epigenetic changes in patients with post-acute COVID-19 symptoms (PACS) and long-COVID: A systematic review by Madhura Shekhar Patil, Emma Richter, Lara Fanning, Jolien Hendrix, Arne Wyns, Laura Barrero Santiago, Jo Nijs, Lode Godderis, Andrea Polli

“…Six studies explored DNA methylation in PACS and/or long-COVID, while two studies explored miRNA expression in long-COVID associated with lung complications. Sample sizes were mostly small and study quality was low or fair. The main limitation of the included studies was a poor characterization of the patient population that made a homogeneous synthesis of the literature challenging. …”
Get full text

Voices from the frontline: findings from a thematic analysis of a rapid online global survey of maternal and newborn health professionals facing the COVID-19 pandemic by Lenka Benova, Aduragbemi Banke-Thomas, Emma Radovich, Francesca L Cavallaro, Andrea Pembe, Oona Maeve Renee Campbell, Thomas van den Akker, Bouchra Assarag, Thérèse Delvaux, Mitsuaki Matsui, Alexandre Delamou, Wendy Jane Graham, Bosede Afolabi, Annettee Nakimuli, Louise Tina Day, Aline Semaan, Constance Audet, Elise Huysmans, Hannah Blencowe, Séverine Caluwaerts, Leonardo Chavane, Giorgia Gon, Peter Kascak, Sarah Moxon

“…Overall, 47% of participants in LMICs and 69% in HICs felt mostly or completely knowledgeable in how to care for COVID-19 maternity patients. …”
Get full text

Dual calcium-voltage optical mapping of regional voltage and calcium signals in intact murine RyR2-R2474S hearts by Yangpeng Li, Zhu Liu, Christopher O'Shea, Jianhong Li, Xian Luo, Tangting Chen, Xianhong Ou, Weichao Liu, Guoliang Hao, Christopher L.-H. Huang, Davor Pavlovic, Xiaoqiu Tan, Ming Lei

“…Such CaT and APD alternans occurred mostly semiannually in specific regions of the ventricular pre-occurrence of VT. …”
Get full text

EGFR pathway subgroups in Chilean colorectal cancer patients, detected by mutational and expression profiles, associated to different clinicopathological features by Karin Alvarez, Paulina Orellana, Cynthia Villarroel, Luis Contreras, Hiroshi Kawachi, Maki Kobayashi, Ana Maria Wielandt, Marjorie De la Fuente, Juan Carlos Triviño, Udo Kronberg, Pilar Carvallo, Francisco López-Köstner

“…Three groups gather mainly early-stage tumors, whereas a fourth group is mostly conformed by advanced tumors. We described here that 71.4% of tumors from one group have a mutated PI3K/PTEN pathway, in comparison to other groups having 32%, 27%, and 25%. …”
Get full text

Wearable defibrillator to improve accuracy in selecting candidates to implantable defibrillator: A real‐world experience by Gabriele Dell'Era, Philippe Caimmi, Enrico Guido Spinoni, Eleonora Battistini, Stefano Porcellini, Federica De Vecchi, Matteo Santagostino, Chiara Ghiglieno, Anna Degiovanni, Fabrizio Leigheb, Daniela Kozel, Andrea Capponi, Giuseppe Patti

“…Abstract Aims The indication for implantable cardioverter defibrillator (ICD) for sudden cardiac death (SCD) prevention relies mostly on left ventricular ejection fraction (LVEF) ≤ 35%. …”
Get full text

Mortality risk associated with clinical signs of possible serious bacterial infection (PSBI) in young infants in Africa and Asia: protocol for a secondary pooled analysis by Adejumoke Idowu Ayede, Samir K Saha, Saifuddin Ahmed, Mohammad Shahidul Islam, Gary L Darmstadt, Fabian Esamai, Antoinette Tshefu Kitoto, Ebunoluwa A Adejuyigbe, Yasir Bin Nisar, Shamim Ahmad Qazi, Vaishnavi Bhamidi, Khusbu Adhikari, Ivana Marić, Robinson D Wammanda

“…Moreover, studies to validate the importance of clinical signs of PSBI have mostly used the need for hospitalisation as the outcome. …”
Get full text

Effects of indoor biophilic environments on cognitive function in elderly patients with diabetes: study protocol for a randomized controlled trial by Jiajia Dai, Jiajia Dai, Mohan Wang, Han Zhang, Zhengfang Wang, Xue Meng, Xue Meng, Yanan Sun, Yanan Sun, Yuan Sun, Yuan Sun, Wenhui Dong, Zhiying Sun, Kuo Liu, Kuo Liu

“…Previous studies have focused mostly on improving cognition in elderly diabetic patients through three methods: medication, cognitive training, and lifestyle intervention. …”
Get full text

Blueprint for clinical N-of-1 strategies with off-label precision treatments in monogenic epilepsies by Victoria M. Defelippe, Eva H. Brilstra, Willem M. Otte, Ghislaine J. M. W. van Thiel, Helen J. Cross, Finbar O’Callaghan, Valentina De Giorgis, Emilio Perucca, Kees P. J. Braun, Floor E. Jansen

“…To date, however, information on the efficacy of these treatments is mostly based on case-reports and retrospective studies. …”
Get full text

The Application and Validity of a New Composite Radiographic Index for Patients with Osteonecrosis of the Jaws by Zafeiroula Yfanti, Sotirios Tetradis, Nikolaos G. Nikitakis, Konstantina Eleni Alexiou, Emmanouil Vardas, Christos Angelopoulos, Kostas Tsiklakis

“…Extensive lytic changes, sclerosis, sequestration, periosteal bone formation, and inferior alveolar canal involvement were mostly observed in clinical Stage 3. Furthermore, a statistically significant correlation between clinical stage and CRIm classification was found (rho = 0.446; <i>p</i>-value < 0.001). …”
Get full text

MTAP deficiency is highly homogeneous in advanced, muscle-invasive urothelial carcinoma of the urinary bladder by Natalia Gorbokon, Katharina Teljuk, Viktor Reiswich, Florian Lutz, Sebastian Dwertmann Rico, Clara Lühr, Christian Bernreuther, Yaryna Klos Al Bunni, Cosima Völkel, Henning Plage, Maximilian Lennartz, Margit Fisch, Sarah Minner, Ronald Simon, Guido Sauter, Henrik Zecha, Stefan Steurer, Thorsten Schlomm, Tatjana Vlajnic, Lukas Bubendorf, Michael Rink, Martina Kluth, Florian Viehweger, Morton Freytag

“…Among 41 consecutive pT2-4 carcinomas from which 1–15 (average 6.4) whole sections were analyzed, MTAP was homogeneously deficient in 34.1%, heterogeneously deficient in 4.9% and homogeneously retained in 61.0%. MTAP deficiency is mostly homogeneous in advanced urothelial carcinoma. …”
Get full text