Impact of aminoglycosides on survival rate and renal outcomes in patients with urosepsis: a multicenter retrospective study by David Rozenblat, Arnaud Serret-Larmande, Alexis Maillard, Romain Arrestier, Sarah Benghanem, Julien Charpentier, Michael Darmon, Vincent Das, François Dépret, Jean Luc Donay, Hervé Jacquier, Hélène Poupet, Jean-Michel Molina, Matthieu Lafaurie

“…Nephrotoxicity is the most common adverse effect of aminoglycosides and acute kidney injury (AKI) has a significant prognostic impact in septic shock. …”
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Analysis of Atomization Cooling Characteristics of External Mixing Nozzles by ZHANG Qian, LIU Ziyang, XU Yuhan, HUANG Lei, WANG Dagui, CHEN Liai, CHEN Song

“…In order to explore the influence of gas-phase pressure and liquid-phase pressure on the atomization effect, reduce the number of simulation groups and be closer to the most real working conditions, the dimensionless factor <italic>K</italic> was introduced to investigate the influence degree of gas-phase and liquid-phase pressure on the velocity of atomized particles, the thickness of the liquid film, the distribution of mist particles and the cooling amount.Results and Discussions　When the liquid phase pressure remains constant, as the gas phase pressure increases, the velocity of the atomized particles keeps increasing. …”
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Grazing exclusion significantly reduced soil organic carbon stocks but enhanced soil inorganic carbon stocks in desert steppe of northwest China by Guangxing Zhao, Zhihao Zhang, Akash Tariq, Rapkat Sabit, Jordi Sardans, Corina Graciano, Xiangyi Li, Yuhe Zhu, Josep Peñuelas, Dhafer A. Al-Bakre, Fanjiang Zeng

“…Grazing exclusion reduced SOCS and mineral-associated organic carbon (MAOC) stocks but promoted SICS and STCS. GE6 exerted the most detrimental impact on the STCS in this region. …”
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Genetic diversity, heritability, and estimated breeding values for growth of domesticated Asian seabass Lates calcarifer from Thailand by Sirikan Prasertlux, Atra Chaimongkol, Jutaporn Chaimongkol, Sirithorn Janpoom, Sureerat Tang, Puttawan Rongmung, Wanwipa Ittarat, Parichart Ninwichian, Putth Songsangjinda, Takashi Sakamoto, Bavornlak Khamnamtong, Panya Sae-Lim, Sirawut Klinbunga

“…FST and genetic heterogeneity analysis revealed significant genetic differences of most pairwise comparisons (P < 0.001). Genetic distance between populations was 0.000–0.703. …”
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Precession-driven low-latitude hydrological cycle paced by shifting perihelion by H. Yang, X. Shi, X. Wang, Q. Liu, Y. Zhong, X. Liu, Y. Sun, Y. Cai, F. Liu, G. Lohmann, M. Werner, Z. Jian, T. M. L. Pinho, H. Cheng, L. Lu, L. Lu, J. Liu, J. Liu, C.-Y. Yang, Q. Yang, Q. Yang, Y. Hu, X. Cheng, J. Zhang, D. Chen

“…Here, the latitude of perihelion is introduced as the latitude of Earth's subsolar point during perihelion, which is the location where the most intense solar radiation is concentrated. At the time of perihelion, intense solar radiation heats the land faster than the ocean due to differing thermal inertia. …”
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Field evaluation of the Bioline Malaria Ag P.f/Pan rapid diagnostic test: causes of microscopy discordance and performance in Uganda by Kisakye Diana Kabbale, Bienvenu Nsengimaana, Francis D. Semakuba, Brian A. Kagurusi, Caroline Mwubaha, Innocent Wiringilimaana, Thomas Katairo, Shahiid Kiyaga, Monica Mbabazi, Samuel Gonahasa, Moses R. Kamya, Stephen Tukwasibwe, Sam L. Nsobya, Victor Asua, Daudi Jjingo, Bosco Agaba, Catherine Maiteki-Sebuguzi, Jimmy Opigo, Kylie Hilton, Sarah G. Staedke, Grant Dorsey, Melissa D. Conrad, Bryan Greenhouse, Isaac Ssewanyana, Jessica Briggs

“…In contrast, false positive RDT results were common, most likely due to persistent HRP2 antigenaemia in this high transmission setting though causes of false positive RDTs were not investigated. …”
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Association of surrogate adiposity markers with prevalence, all-cause mortality and long-term survival of heart failure: a retrospective study from NHANES database by Fan-Shun Guo, Fan-Shun Guo, Chen Guo, Chen Guo, Jia-Hao Dou, Jia-Hao Dou, Jun-Xiang Wang, Rui-Yun Wu, Rui-Yun Wu, Shou-Fang Song, Shou-Fang Song, Xue-Lu Sun, Xue-Lu Sun, Yi-Wei Hu, Yi-Wei Hu, Jin Wei, Jin Wei

“…The objective of this study was to explore which adiposity marker is most highly correlated with HF prevalence, all-cause mortality and patients’ long-term survival.MethodsThe National Health and Nutrition Examination Survey (NHANES) database provided all the data for this study. …”
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Lung disease in relation to unique monocyte-macrophage subpopulations induced by combined inhalant endotoxin and collagen-induced arthritis by Jill A. Poole, Aaron Schwab, Geoffrey M. Thiele, Geoffrey M. Thiele, Todd A. Wyatt, Todd A. Wyatt, Todd A. Wyatt, Amy J. Nelson, Oliver W. Schanze, Angela Gleason, Michael J. Duryee, Michael J. Duryee, Bryant R. England, Bryant R. England, Ted R. Mikuls, Ted R. Mikuls

“…BackgroundLung disease is the most overrepresented cause of death in rheumatoid arthritis (RA). …”
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Experience with Tixagevimab and Cilgavimab (Evusheld) in 86 rheumatic patients undergoing anti-B cell therapy with rituximab by T. V. Beketova, N. О. Levina, M. V. Dubinskaia, Yu. A. Uskova, I. V. Rozanova, V. V. Babak, M. F. Beketova, T. N. Krasnova

“…Good TC’s tolerability was noted, signs not associated with COVID-19 or progression of IMRD after administration of TC were observed in 8 (9%) patients (GPA – 3 MPA – 1, RA – 2, SLE – 1, IgG4-related disease – 1), adverse reactions definitely associated with the use of TC were not found. The most serious event not associated with coronavirus infection was the progression of polyneuropathy in a patient with RA. …”
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APPLICATION OF OBJECTIVE AND SUBJECTIVE EVALUATION METHODS FOR MASTICATORY FUNCTION IN PATIENTS WITH MANDIBULAR OVERDENTURES by R.R. Bratus-Hrynkiv, A.Yu. Kordiiak

“… Appropriate chewing function is an important indicator of oral health, and masticatory efficiency assessment is one of the most objective methods of prosthetic treatment quality control. …”
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Use the 4S (Signal-Safe Speckle Subtraction): Explainable Machine Learning Reveals the Giant Exoplanet AF Lep b in High-contrast Imaging Data from 2011 by Markus J. Bonse, Timothy D. Gebhard, Felix A. Dannert, Olivier Absil, Faustine Cantalloube, Valentin Christiaens, Gabriele Cugno, Emily O. Garvin, Jean Hayoz, Markus Kasper, Elisabeth Matthews, Bernhard Schölkopf, Sascha P. Quanz

“…In the present work, we use explainable machine learning to investigate the reason for the loss of the planet signal for one of the most used postprocessing methods: principal component analysis (PCA). …”
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Constraining Star Formation in M87 Using Deep Hubble Space Telescope UV Data by Prathamesh Tamhane, William Waldron, Ming Sun, Silvia Martocchia, Claudia Maraston, Alessandro Boselli, William Forman, Massimo Gaspari, Juhi Tiwari, Megan Donahue, G. Mark Voit, Tim Edge, Grant Tremblay, Daniel Thomas

“…We analyzed the deepest Hubble Space Telescope F275W ultraviolet (UV) imaging of M87 to obtain the most robust constraints on its star formation rate (SFR) and star formation history (SFH). …”
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High-Throughput Indirect Monitoring of TORC1 Activation Using the pTOMAN-G Plasmid in Yeast by Melissa Gómez, Guilherme Rocha, Diego Ruiz, Claudio Martínez, Francisco Salinas, Eduardo Kessi-Pérez

“…As a proof of concept, this methodology allowed phenotyping a large population of yeast strains derived from the 1002 Yeast Genomes Project, the most complete catalog of genetic variation in yeasts. …”
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Potential New Avian Species as Carriers of Diverse Circoviruses by Yasmin Luisa Neves Lemes Garcia, Ana Júlia Chaves Gomes, Guilherme Guerra Neto, Natasha Fujii Ando, Camila Sanches Rodrigues, Richard Alegria Cesario, Camila Domit, Fábio Henrique Lima, Helena Lage Ferreira, João Pessoa Araújo, Bruna Lindolfo da Silva, Fernando Rosado Spilki, Luciano Matsumiya Thomazelli, Thais Helena Martins Gamon, Isabela Barbosa Assis, Edison Luiz Durigon, Danielle Bruna Leal Oliveira, Vivaldo Gomes da Costa, Marília de Freitas Calmon, Paula Rahal

“…Regarding the results, a total of 1528 swab samples were collected from 601 birds, of which 24 (4%, 95% CI: 2.4–5.6) tested positive for various circovirus subtypes. Most positive birds (92%, 22/24) were from the northwest region of São Paulo, mainly from the city of São José do Rio Preto (54%, 12/22). …”
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Succinic acid reduces tomato bacterial wilt disease by recruiting Sphingomonas sp by Ningqi Wang, Ling Ping, Xinlan Mei, Yaozhong Zhang, Yuling Zhang, Xinrun Yang, Yuting Guo, Yang Gao, Yangchun Xu, Qirong Shen, Tianjie Yang, Zhong Wei

“…Results Seventeen of the exudates reduced the disease index, with most having neutral or even promotive effects on R. solanacearum growth. …”
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Retrospective analysis of children with 46,XX testicular/ovotesticular DSD: a 10-year single-center experience by Yan Gong, Xiaoqin Yin, Jing Xu, Yan Li, Qingxu Liu, Shasha Zhou, Fei Wang, Yiqing Lyu, Sheng Guo, Wenyan Huang, Pin Li

“…However, immunohistochemical analysis revealed that 2 of 16 children were OCT3/4 positive. The most frequent type of gonadal pathology (17/47) was bilateral seminiferous tubules. …”
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Leveraged Vaccination to Alleviate Original Antigenic Sin for Enhancing Broad‐Neutralizing Antibody Response against SARS‐CoV‐2 Omicron Subvariants by Guangxu Zhang, Qian Wang, Kai Ji, Yuanzhou Wang, Wei Xu, Jie Zhou, Zezhong Liu, Ruixue Xiu, Lixiao Xing, Jianghao Zhou, Yuren Shi, Xishan Lu, Xuanyi Wang, Bo Ying, Lu Lu, Shibo Jiang

“…We found that prime with WT–RBD and boost with XBB–RBD resulted in significantly higher bnAb response against most Omicron subvariants tested than that after prime with WT–RBD and boost with BA.2–RBD because the antigenic distance between WT–RBD and XBB–RBD is much longer than that between WT–RBD and BA.2–RBD. …”
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Design and Validation of a Multi-Epitope mRNA Vaccine Construct Against Human Monkeypox Virus (hMPXV) by Annotating Protein of Intracellular Mature Virus (IMV) Form of hMPXV by Mohammad Asrar Izhari, Siraj B. Alharthi, Raed A. Alharbi, Ahmad H. A. Almontasheri, Wael A. Alghamdi, Abdulmajeed Abdulghani A. Sindi, Ahmad Abdulmajed Salem, Ali Mahzari, Fahad Alghamdi, Ahmed R. A. Gosady

“…<b>Results</b>: The MPXV-2-Beta vaccine constructs, of the six initially designed constructs, was identified as the most promising candidate, signifying nonallergenic profile and nontoxic features, with a predicted antigenicity score (PAS) = 0.7202, 407 residues, a molecular weight of 43,102.1 Da, pI of 9.2, and favorable stability parameters (AI: 65.65, GRAVY: −0.597, I-i: 25.92). …”
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Global biome changes over the last 21&thinsp;000 years inferred from model–data comparisons by C. Li, C. Li, A. Dallmeyer, J. Ni, M. Chevalier, M. Willeit, A. A. Andreev, X. Cao, L. Schild, L. Schild, B. Heim, M. Wieczorek, U. Herzschuh, U. Herzschuh, U. Herzschuh

“…<p>We present a global megabiome reconstruction for 43 time slices at 500-year intervals throughout the last 21 000 years based on an updated, and thus currently the most extensive, global taxonomically and temporally standardized fossil pollen dataset of 3455 records. …”
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Mapping clay fraction oxides in Brazil using Earth observation strategy by Jorge Tadeu Fim Rosas, José A.M. Demattê, Nícolas Augusto Rosin, Raul Roberto Poppiel, Nélida E.Q. Silvero, Merilyn Taynara Accorsi Amorim, Heidy S. Rodríguez-Albarracín, Letícia Guadagnin Vogel, Bruno dos Anjos Bartsch, José João Lelis Leal de Souza, Lucas de Carvalho Gomes, Danilo César de Mello

“…Despite their importance of these oxides, quantifying them on a large scale presents significant challenges. The most common method is laboratory sulfuric acid digestion, which is expensive, complex, and environmentally detrimental. …”
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