Diabetes is causally associated with increased breast cancer mortality by inducing FIBCD1 to activate MCM5-mediated cell cycle arrest via modulating H3K27ac by Binbin Tan, Yang Liu, Qianqian Chen, Weijie Yang, Wenhan Yang, Kaiping Gao, Li Fu, Tiantian Zhang, Penglong Chen, Yongyi Huang, Yuting Wang, Guoqiang Zhang, Juan Xiong, Rihong Zhai

“…Abstract Breast cancer (BC) is the most common tumor worldwide and it has been recognized that up to one third of BC patients have co-existing diabetes mellitus (DM) (BC-DM). …”
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Mechanisms of Cefiderocol Resistance in Carbapenemase-Producing Enterobacterales: Insights from Comparative Genomics by Alexander Tristancho-Baró, Ana Isabel López-Calleja, Ana Milagro, Mónica Ariza, Víctor Viñeta, Blanca Fortuño, Concepción López, Miriam Latorre-Millán, Laura Clusa, David Badenas-Alzugaray, Rosa Martínez, Carmen Torres, Antonio Rezusta

“…<b>Results</b>: A total of 59 isolates (29 resistant and 30 susceptible) were analyzed, predominantly comprising <i>Klebsiella pneumoniae</i>, <i>Escherichia coli</i>, and <i>Enterobacter cloacae</i>. The most frequent carbapenemase gene among the resistant isolates was <i>bla</i>_NDM, which was also present in a subset of susceptible strains. …”
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Epidemiology and risk factors for endoparasite infection in subtropical feral cattle in Hong Kong by Tania A. Perroux, Samantha S.Y. Lie, Alan G. McElligott, Danchen A. Yang, Fraser I. Hill, George M.W. Hodgson, Wing S. Wong, Kate J. Flay

“…Trematode infections were the most prevalent (91.22 %), followed by protozoan (67.17 %), nematode (23.22 %) and cestode (12.97 %) infections. …”
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Nitrogen use efficiency in high soil-plant nitrogen pool: Fertilizer management optimization via the DNDC model in rice fields by Zongkui Chen, Xiangyu Xu, Jiayue Wang, Wenqi Yuan, Xiaomeng Shen, William D. Batchelor, Zhiyuan Yang, Yongjian Sun, Jun Ma, Xiafei Li

“…Consequently, superior GMN50-100 proved the most effective approach for sustaining high NUE under high SPNP conditions.…”
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Soil-transmitted helminth infection, loss of education and cognitive impairment in school-aged children: A systematic review and meta-analysis. by Noel Pabalan, Eloisa Singian, Lani Tabangay, Hamdi Jarjanazi, Michael J Boivin, Amara E Ezeamama

“…Cautious interpretation is warranted due to high ROB in some of the primary literature and high between study variability in most domains. Notwithstanding, this synthesis provides empirical support for a cognitive and educational benefit of deworming. …”
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Schema-Informed Digital Mental Health Intervention for Maladaptive Cognitive-Emotional Patterns: Randomized Controlled Trial by Seohyun Jeong, Hyeonseong Kim, Silvia Kyungjin Lho, Inae Hwang, Seongjun Mun, Soohyun Kim, Hyejin Lim, Hyeonhee Kim, Min-Sup Shin, Woori Moon

“…Secondary outcomes (eg, depression, trait anxiety, and self-efficacy) also improved across most programs. These effects were maintained at a 1-month follow-up. …”
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Take charge during treatment: a protocol for a pilot study to evaluate the impact of exercise on cardiovascular biomarkers among black and white breast cancer patients undergoing t... by Natalia Do Couto, Mary Hidde, Georgios Grigoriadis, Rodney Sparapani, Matt Durand, Michael Widlansky, Courtney Jankowski, Madeline Berendt, Bethany Canales, Sarah Golus, Laura E. Norwood Toro, Purushottam Laud, Amanda Kong, Kent Hoskins, David Lewandowski, Shane A. Phillips, David D. Gutterman, Alison J. Kriegel, Kirsten M. M. Beyer, Andreas M. Beyer, Melinda Stolley

“…Non-Hispanic black/African American (NHB) women are at higher risk for CTx induced cardiotoxicity compared to Non-Hispanic White (NHW) women. To date, most study efforts to mitigate cardiotoxicity target large vessels and cardiac damage. …”
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Novel Atmospherically Plasma Sprayed Micro Porous Layer for Anion Exchange Membrane Water Electrolysis Operating With Supporting Electrolyte by Vincent Wilke, Marco Rivera, Tobias Morawietz, Noriko Sata, Lukas Mues, Manuel Hegelheimer, Artjom Maljusch, Patrick Borowski, Günter Schmid, Chen Yie Thum, Malte Klingenhof, Peter Strasser, André Karl, Shibabrata Basak, Jean‐Pierre Poc, Rüdiger‐A. Eichel, Aldo Saul Gago, Kaspar Andreas Friedrich

“…ABSTRACT Anion exchange membrane water electrolysis (AEMWE) is one of the most promising candidates for green hydrogen production needed for the de‐fossilization of the global economy. …”
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Estimation of Maximum Obtainable RBE ‘Turnover-Points’ (LET_U) for Accelerated Ions Based on a Nuclear Charge Radius Hypothesis to Obtain Iso-Effective LET and RBE Values... by Bleddyn Jones

“…These exponents are lower than 0.66 and 0.33 (those for nuclear cross-sections and spherical nuclear radii, respectively), but suggest prolate nuclear shapes in most of the ions studied. Worked examples of estimating isoeffective LET values for two different ions are provided. …”
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Narrow-Margin Treatment with Modified Mohs Microsurgery for Extramammary Paget&amp;rsquo;s Disease: A Retrospective Clinical Analysis by Yang J, Yan J, Luo H, Li L, Jiang L, Chen X, Wu L, Chai J, Xue H, Gan L, Liu Y, Chen J, Fei W, Bai Y, Zhu Q, Chen Z, Guo L, Chen Y

“…The primary objectives of this study were to assess the long-term local recurrence rates of tumors treated with narrow-margin mMMS and to explore the final margin width as well as the factors that may influence postoperative recurrence.Results: A total of 52 patients were included in this retrospective study. Most patients were male (n = 48, 92.3%) with a mean age of 69.5 years (SD:9.08, range:44– 91). …”
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Comparative Characteristics of Patients with Cerebral Stroke and Myocardial Infarction in Outpatient Practice: Structure of Comorbidity, Risk Factors, Drug Treatment and Outcomes by A. N. Vorobyev, K. G. Pereverzeva, M. M. Loukianov, S. S. Yakushin, S. Yu. Martsevich, E. Yu. Okshina, O. M. Drapkina

“…Clinical and anamnestic characteristics, risk factors, prescribed pharmacotherapy, and its compliance with clinical guidelines were evaluated.Results. Most of the patients in the REGION-AR and REGATA registries were diagnosed with arterial hypertension (AH; 97.1% and 98.5%), coronary heart disease (СHD; 75.1% and 100%), chronic heart failure (CHF; 74.0% and 94.8%), and the proportion of atrial fibrillation (AF) cases were 20.9% and 23.3%, respectively. …”
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A one year longitudinal study of cortical myelination changes following pediatric mild traumatic brain injury by Jessica R. McQuaid, Tracey V. Wick, Josef Ling, Andrew B. Dodd, Divyasree Sasi Kumar, Upasana Nathaniel, Samuel D. Miller, Vadim Zotev, Harm J. van der Horn, John P. Phillips, Richard A. Campbell, Robert E. Sapien, Timothy B. Meier, Andrew R. Mayer

“…Myelin content increased with chronological age and as a function of individual aging across study visits in a hemisphere specific fashion (left > right), most visibly within the posterior parietal lobe. …”
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Comparison of the long-term prognostic value of different frailty instruments in older inpatients: a 5-year prospective cohort study by Min Zeng, Yu-Hao Wan, Yao-Dan Liang, Jing Shi, Zhi-Kai Yang, Ting Wang, Chen Ji, Wei He, Ning Sun, Di Guo, Ling-Ling Cui, Lin Yang, Jie-Fu Yang, Hua Wang

“…CFS is the preferred frailty screening scale, while CGA-FI is the most accurate assessment scale. Trial registration ChiCTR1800017204 (07/18/2018).…”
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The Prognostic Value of Platelet Kinetics Assessment in Pediatric Chronic Idiopathic Thrombocytopenic Purpura by Nebojsa Igrutinovic, Jelena Pantovic, Bojana Markovic, Marija Medovic, Milica Cekerevac, Vladimir Markovic, Strahinja Odalovic, Sanja Knezevic, Ana Vujic, Isidora Mihajlovic, Nevena Stojadinovic, Dragan Knezevic, Nina Urakovic, Ivana Andrejevic, Gordana J. Ristic, Vladimir Slavkovic, Kristina Andric, Rasa Medovic

“…The remaining 10%, which represented the most severe cases, required all available therapies, had equally mixed and liver sequestration, and splenectomy showed no effect. …”
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Factors Influencing Binge-watching Behaviour and its Impact on Loneliness among Undergraduate Medical Students: A Cross-sectional Study from Chengalpattu District, Tamil Nadu, Indi... by R Suba Shree, P Kaveri, Roshni Mary Peter, VV Anantharaman, M Logaraj

“…Results: The participants had a mean age of 20.71±2.04 years, with the majority being females (58.6%) and from nuclear families (86.1%). Most students (84.4%) had subscriptions to OTT platforms, with 50.8% binge-watching more than twice a week. …”
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Territorial and social inequalities in mental distress and self-perceived health among schooled adolescents: a cross-sectional study in central Catalonia and Barcelona by Helena González-Casals, Carmen Vives-Cases, María José López, Belén Sanz-Barbero, Katherine Pérez, Gloria Perez, Mònica Cortés-Albaladejo, Gemma Serral, Maria A Barceló, Isabel Ruiz-Pérez, Inmaculada Mateo-Rodríguez, Andrés Cabrera-León, Marina Bosque-Prous, Cinta Folch, Albert Espelt

“…This study underscores the importance of taking a holistic approach when developing preventive and promotion strategies for adolescent health, addressing different levels of intervention while focusing on the most vulnerable populations.…”
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Caracterización clínica, epidemiológica y genealógica de la esquizofrenia en pacientes de la Policlínica Alcides Pino Bermúdez de Holguín by Maydoli Cardet Escalona, Olga Antonia Álvarez Estrabao, Sara Meneses Álvarez

“…ABSTRACT   Background: Schizophrenia is the most common cause of chronic mental illness that affects approximately 1% of the population and is a group of psychotic disorders that is frequent in adolescents and young adults. …”
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Diabetes management during and after Ramadan among pregnant women in Saudi Arabia: exploring self-efficacy, self-care, and glycemic control by Omar Mohammed Alamri, António Raposo, Ayoub Ali Alshaikh, Hani A. Alfheeaid, Ali Mohammed Alamri, Mohammed Abdullah Alasmri, Nada Mohammed Alwubayran, Ahmed Khaled Shukri, Thamer Alslamah, Najla A. Albaridi, Md Faruque Ahmad, Abdullah Y. Otayf, Ariana Saraiva, Ariana Saraiva, Najim Z. Alshahrani

“…HbA1c distribution shifted slightly, with fewer participants in the &lt;5.7% range after Ramadan and more in the 5.7–6.4% range. Most managed diabetes using oral drugs with diet and exercise (42%). …”
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An Updated Indirect Comparison of Elranatamab Versus a Real-World External Control Arm in Triple-Class Refractory Multiple Myeloma by Costa LJ, LeBlanc TW, Tesch H, Sonneveld P, Johnson SM, Vekeman F, Hlavacek P, Meche A, Kim CH, Cislo P, Hughes DM, Nador G, DiBonaventura M

“…The registrational Phase 2 MagnetisMM-3 (NCT04649359) trial was single-armed; the aim of this indirect comparison was to contextualize the efficacy of the most recent 28.4-month follow-up data cut from this trial, allowing for more mature data, with real-world data serving as an external control.Patients and Methods: We conducted a retrospective cohort study to indirectly compare the efficacy observed in the elranatamab arm of MagnetisMM-3 Cohort A (BCMA-naïve; N=123) from the March 26, 2024 data cut with COTA, a US-based oncology electronic health record database, as an external control. …”
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Measuring growth, resistance, and recovery after artemisinin treatment of Plasmodium falciparum in a single semi-high-throughput assay by Mackenzie A. C. Sievert, Tarrick Qahash, Puspendra P. Singh, Douglas A. Shoue, Lisa A. Checkley, Katelyn Vendrely Brenneman, Zione Cassady, Sudhir Kumar, Xue Li, François H. Nosten, Timothy J. C. Anderson, Ashley M. Vaughan, Jeanne Romero-Severson, Michael T. Ferdig

“…Resistance measured at 120 h continually shows the most consistent phenotype for ring stage susceptibility. …”
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