Serum adipsin levels in rheumatic diseases: defining its role in disease activity and progression in rheumatoid arthritis and axial spondyloarthritis by Marta Novella-Navarro, Marta Novella-Navarro, Laura González-Sánchez, Laura González-Sánchez, Borja Hernández-Breijo, Rebeca Pérez De Diego, Pilar Sánchez-Corral, Margarita López-Trascasa, Margarita López-Trascasa, Maria-Eugenia Miranda-Carús, Maria-Eugenia Miranda-Carús, Alejandro Villalba, Alejandro Villalba, Alejandro Balsa, Alejandro Balsa, Eugenio De Miguel, Eugenio De Miguel, Chamaida Plasencia-Rodríguez, Chamaida Plasencia-Rodríguez, Fernando Corvillo

“…Rheumatoid arthritis (RA) and axial spondyloarthritis (axSpA) are the most common rheumatic diseases (RDs). They are characterised by chronic inflammation of the joints and musculoskeletal components. …”
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Modulation of genetic associations with serum urate levels by body-mass-index in humans. by Jennifer E Huffman, Eva Albrecht, Alexander Teumer, Massimo Mangino, Karen Kapur, Toby Johnson, Zoltán Kutalik, Nicola Pirastu, Giorgio Pistis, Lorna M Lopez, Toomas Haller, Perttu Salo, Anuj Goel, Man Li, Toshiko Tanaka, Abbas Dehghan, Daniela Ruggiero, Giovanni Malerba, Albert V Smith, Ilja M Nolte, Laura Portas, Amanda Phipps-Green, Lora Boteva, Pau Navarro, Asa Johansson, Andrew A Hicks, Ozren Polasek, Tõnu Esko, John F Peden, Sarah E Harris, Federico Murgia, Sarah H Wild, Albert Tenesa, Adrienne Tin, Evelin Mihailov, Anne Grotevendt, Gauti K Gislason, Josef Coresh, Pio D'Adamo, Sheila Ulivi, Peter Vollenweider, Gerard Waeber, Susan Campbell, Ivana Kolcic, Krista Fisher, Margus Viigimaa, Jeffrey E Metter, Corrado Masciullo, Elisabetta Trabetti, Cristina Bombieri, Rossella Sorice, Angela Döring, Eva Reischl, Konstantin Strauch, Albert Hofman, Andre G Uitterlinden, Melanie Waldenberger, H-Erich Wichmann, Gail Davies, Alan J Gow, Nicola Dalbeth, Lisa Stamp, Johannes H Smit, Mirna Kirin, Ramaiah Nagaraja, Matthias Nauck, Claudia Schurmann, Kathrin Budde, Susan M Farrington, Evropi Theodoratou, Antti Jula, Veikko Salomaa, Cinzia Sala, Christian Hengstenberg, Michel Burnier, Reedik Mägi, Norman Klopp, Stefan Kloiber, Sabine Schipf, Samuli Ripatti, Stefano Cabras, Nicole Soranzo, Georg Homuth, Teresa Nutile, Patricia B Munroe, Nicholas Hastie, Harry Campbell, Igor Rudan, Claudia Cabrera, Chris Haley, Oscar H Franco, Tony R Merriman, Vilmundur Gudnason, Mario Pirastu, Brenda W Penninx, Harold Snieder, Andres Metspalu, Marina Ciullo, Peter P Pramstaller, Cornelia M van Duijn, Luigi Ferrucci, Giovanni Gambaro, Ian J Deary, Malcolm G Dunlop, James F Wilson, Paolo Gasparini, Ulf Gyllensten, Tim D Spector, Alan F Wright, Caroline Hayward, Hugh Watkins, Markus Perola, Murielle Bochud, W H Linda Kao, Mark Caulfield, Daniela Toniolo, Henry Völzke, Christian Gieger, Anna Köttgen, Veronique Vitart

“…All top ranking loci for urate effect differences between BMI categories were novel and most had small magnitude but opposite direction effects between strata. …”
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An evaluation of postprandial glucose excursions in type 2 diabetic mellitus subjects on Monotard® HM (ge) versus Humulin N® or Humulin L® insulin, each in combination with metform... by Nirasha Singh, V. Rambiritch, L. Mayet

“…Conclusion: In this study, HN, M and HL, each in combination with metformin, were not effective in controlling postprandial hyperglycaemia. HN was most effective in lowering the postprandial profile, although this was not statistically significant. …”
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Variation patterns of physical property parameters for pipeline transportation of impurity-containing NH3 by Pengbo YIN, Bo WANG, Zhenchao LI, Chaofei NIE, Jiaqing LI, Xiucan JIA, Lin TENG, Lilong JIANG

“…ObjectivePipeline transportation is one of the most economical and safest methods for the large-scale transport of ammonia (NH3), which is recognized as a clean energy source. …”
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Fisuras en la Protección de los Derechos de la Infancia || Cracks in the Protection of the Rights of the Child by Teresa Picontó Novales

“….), which correctly point out some of the most significant omissions and deficiencies in the Convention on the Rights of the Child on both a theoretical and a practical level which, at the very least, need to be taken into account in any reflection leading to a dialogue between these theoretical and empirical currents. …”
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Global trends in esophageal cancer: sex and age disparities in health inequalities from 1990 to 2021, with projections to 2050 by Ying Liu, Ying Liu, Erman Wu, Erman Wu, Fang Cheng, Meng Zhang, Qian Rou, Zenati Nuertai, Maorong Xu, Shanshan Xu, Minghui Li, Lei Zhang, Aheli Nasiroula

“…A decreasing trend is observed in most countries and regions worldwide, particularly in East Asia, with projections suggesting a continued decline in the future.ConclusionAlthough projections indicate a decreasing trend, health inequalities have intensified. …”
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Review Tentang Kemampuan Ikan Ekstremofil Untuk Hidup Di Perairan Asam Dan Terkontaminasi Logam Berat Pascapenambangan Timah by Andri Kurniawan, Diah Mustikasari

“…Some extremophile fishes can survive under habitat conditions considered inhospitable for most fishes due to the presence of the environment stressors. …”
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Vaginal microbiome dysbiosis and sexually transmitted infections correlate with concentrations of immunoglobulin isotypes in human cervicovaginal mucus: insights into HIV-1 transmi... by Matrona M. Akiso, Matrona M. Akiso, Israel Abook, Marianne W. Mureithi, Marianne W. Mureithi, Janet Kombo, Janet Kombo, Print Koi, Print Koi, Joel Musando, Ruth J. Chirchir, Michael D. McRaven, Ann M. Carias, Sarah Joseph, Omu Anzala, Omu Anzala, Thomas J. Hope

“…IntroductionLittle is known about the relationship between antibody isotype in cervicovaginal mucus (CVM) and the local microenvironment and how this impacts HIV-1 transmission at the female genital mucosa.MethodsIn a cohort of 139 adult women in Kenya, we measured antibody isotypes in CVM and describe their associations with local pH, serum concentrations of estrogen and progesterone, and sexually transmitted infections (STIs), including HIV-1.ResultsWe found that immunoglobulin G2 (IgG2) was the most abundant and IgG4 was the least abundant in the CVM. …”
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Revisión de los planes de vigilancia ambiental y siniestralidad en parques eólicos del País Vasco by Alvaro Camiña Cardenal, Nana Vicente Illoro, Justo Martín Martín

“…Between 1999 and 2023, 829 bird and 28 bat fatalities were recorded, involving 80 and 6 species, respectively. The most numerous affected species were the yellow-legged gull, Larus michahellis Naumann, 1840 (232 collisions), and the Eurasian griffon vulture Gyps fulvus Hablizl, 1783 (199 fatalities). …”
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Does the IL-6/KL-6 ratio distinguish different phenotypes in COVID-19 Acute Respiratory Distress Syndrome? An observational study stemmed from prospectively derived clinical, biolo... by Nicolas Partouche, Myriam Maumy, Thien-Nga Chamaraux-Tran, Frederic Bertrand, Francis Schneider, Nicolas Meyer, Morgane Solis, Samira Fafi-Kremer, Eric Noll, Julien Pottecher

“…One hundred and forty-eight ventilated COVID-19 ICU patients from the COVID HUS cohort were assessed for eligibility and 77 were included in the full analysis. Most were male, all were under invasive mechanical ventilation and vasopressor therapy and displayed high severity scores (SAPSII: 48 [42-56]; SOFA: 8 [7-10]). …”
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Drivers of the spatiotemporal distribution of dissolved nitrous oxide and air–sea exchange in a coastal Mediterranean area by S. Flecha, M. de la Paz, F. F. Pérez, N. Marbà, C. Morell, E. Alou-Font, J. Tintoré, J. Tintoré, I. E. Hendriks

“…<p>Among the well-known greenhouse gases (GHGs), nitrous oxide (<span class="inline-formula">N₂O</span>) is the third most impactful, possessing a global warming potential approximately 300 times greater than that of carbon dioxide (<span class="inline-formula">CO₂</span>) over a century. …”
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SINGLE AND MULTIPLE ISCHEMIC BRAIN MICROLESIONS AFTER CAROTID ARTERY STENTING by E. S. Bulgakova, T. V. Tvorogova, В. A. Rudenko, O. М. Drapkina

“…Aim. To identify most probable cardiovascular predictors of periprocedural ischemic brain microlesions after carotid artery stenting (CAS) accounting its presumable pathogenesis.Material and methods. 84 patients with carotid artery stenosis undergoing CAS in a specialized medical center were examined. …”
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Comparative efficacy of infliximab and adalimumab in patients with ankylosing spondylitis by Tatyana Valentinovna Mezenova, V P Tyurin, S Yu Davidyan, N A Kiryukhina, A V Elonakov

“…Adverse reactions (AR) were found in 37 and 33% in the IFN and ADA groups, respectively. The most common AR (elevated hepatic enzymes) was seen in 11 and 9% in Groups 1 and 2, respectively. …”
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Precise aftershock activity in the marine source region of the 2024 Noto-Hanto earthquake by rapid response observation using ocean bottom seismometers by Masanao Shinohara, Ryota Hino, Tsutomu Takahashi, Koichiro Obana, Shuichi Kodaira, Ryosuke Azuma, Tomoaki Yamada, Takeshi Akuhara, Yusuke Yamashita, Eiji Kurashimo, Yoshio Murai, Takehi lsse, Kazuo Nakahigashi, Hisatoshi Baba, Yusaku Ohta, Yoshihiro Ito, Hiroshi Yakiwara, Yukihiro Nakatani, Gou Fujie, Toshinori Sato, Hajime Shiobara, Kimihiro Mochizuki, Shin’ichi Sakai, The R/V Hakuho-maru KH-24-JE01 and KH-24-JE02C shipboard science parties

“…The aftershock depths mostly ranged from 0.2 km to 17 km. Although the aftershock activity seems to be confined in the upper crust, relatively deep events occurred in the easternmost source region. …”
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The new 222‐nm far ultraviolet‐C lowers bacterial contamination to endoscopists during esophagogastroduodenoscopy by Yukari Fukutoku, Hidezumi Kikuchi, Kentaro Hoshi, Kouji Narita, Taka Asari, Kuniaki Miyazawa, Yohei Sawada, Shiro Hayamizu, Tetsuya Tatsuta, Shinji Oota, Keisuke Hasui, Hiroto Hiraga, Daisuke Chinda, Tatsuya Mikami, Phawinee Subsomwong, Krisana Asano, Kyosuke Yamane, Yoshimasa Ogawa, Masahiro Sasaki, Toru Koi, Hiroyuki Ohashi, Akio Nakane, Hirotake Sakuraba

“…Results The bacterial culture positivity in the UV group (5.03%) was significantly lower than that in the non‐UV group (25.76%), p < 0.0001. Most of the bacteria identified in the UV and non‐UV groups were normal constituents of the oral flora, including Streptococcus salivarius and Staphylococci. …”
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A clinical case of single-stage correction of penetration combined orofacial defect with two microsurgical autografts by A. D. Kaprin, A. P. Polyakov, M. V. Ratushnyi, O. V. Matorin, M. M. Filyushin, V. N. Vasilyev, I. V. Rebrikova, A. L. Sugaipov

“…Herzen Moscow Oncology Research Institute, Ministry of Health of Russia, has gained experience in comprehensively correcting extensive combined maxillofacial defects with two or more grafts in 27 patients who underwent autografting with a total of 73 flaps. The most functionally incapacitating and life-incompatible defect was removed at Stage 1 of reconstructive treatment. …”
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Curative resection after chemotherapy and chemoradiotherapy for postoperative recurrence of pancreatic tail cancer in the abdominal wall: a case report by Shunya Iio, Yuto Hozaka, Kiyonori Tanoue, Tetsuya Idichi, Kousuke Fukuda, Taiki Nakashima, Ryutaro Yasudome, Yoichi Yamasaki, Yota Kawasaki, Takaaki Arigami, Akihiro Nakajo, Michiyo Higashi, Yuko Mataki, Hiroshi Kurahara, Takao Ohtsuka

“…Abstract Background Locoregional recurrence and metastasis to the liver, peritoneum, and lung are the most common recurrent patterns of pancreatic ductal adenocarcinoma (PDAC) after radical resection. …”
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TCR-based cellular immunotherapy for hepatocellular carcinoma: advances, challenges, and prospects by Wanting Zeng, Wei Zhu, Guosheng Yuan, Jinzhang Chen, Zhanhui Wang, Jinlin Hou, De-Ke Jiang

“…Abstract Hepatocellular carcinoma (HCC) ranks among the most prevalent malignant tumors globally. However, current frontline treatment modalities fail to achieve satisfactory therapeutic outcomes. …”
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Dihydroartemisinin enhances remyelination by switching microglia to the reparative phenotype by Li Liu, Lina Yang, Xinke Du, Xiaoxi Kan, Qingsen Ran, Yang Zhang, Manjing Li, Qingwu Liu, Yujie Li, Qing Yang, Ying Chen, Keshan Dong, Xiaoxin Zhu, Qi Li

“…Abstract Background Boosting myelin repair is widely recognized as one of the most powerful approaches for demyelinating therapy, essentially contributing to the recovery of neurological functions. …”
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Hypotensive episodes on program hemodialysis during dialysis procedure: modern approach for diagnostics, prophylaxis and correction by V. Yu. Shilo, I. Yu. Drachev

“…There weren»t any significant differences in «hemodialysis-dose effectiveness» (Kt/V) in both groups; however, in the ASPC group target values of inorganic phosphorus in serum (for a dialysis patient) were reached which is one of the most important parameters of hemodialysis adequacy. …”
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