Centering peers in design and training for a peer-delivered contingency management program for self-identified harm reduction and treatment goals by Linda Peng, Erin Stack, Alexis Cooke, Bryan Hartzler, Ryan Cook, Gillian Leichtling, Christi Hildebran, Judith Leahy, Kelsey Smith Payne, Lynn Kunkel, Kim Hoffman, P. Todd Korthuis

“…Contingency management (CM) is the most effective intervention for stimulant use disorder and may engage non-treatment-seeking populations, especially when delivered by peer recovery support specialists (peers). …”
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Risk factors for glucocorticoid induced osteoporosis in young adults by Helena Florez, Josep Lluis Carrasco, Martina Barberá, José Hernández-Rodríguez, Africa Muxi, Anastasia Mocritcaia, Sergio Prieto-González, Maria C. Cid, Ana Monegal, Núria Guañabens, Pilar Peris

“…IntroductionGlucocorticoid-induced osteoporosis (GIOP) is one of the most frequent causes of secondary osteoporosis, especially in young subjects. …”
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Total endovascular arch repair: Initial experience in BolognaCentral MessagePerspective by Luca Di Marco, MD, PhD, Chiara Nocera, MD, PhD, Francesco Buia, MD, Francesco Campanini, MD, Domenico Attinà, MD, Giacomo Murana, MD, Luigi Lovato, MD, Davide Pacini, MD, PhD

“…Mean age was 74.7 ± 7.8 years. The most frequent procedure was fenestrated endovascular aortic repair with a left carotid-subclavian bypass (LCSB) (6; 40%), followed by double-branched graft with LCSB (5; 33.3%) and triple-branched graft (2; 13.3%) and scalloped graft with LCSB (2; 13.3%). …”
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Chromosomal abnormalities in couples with recurrent pregnancy loss: a 16-year cross-sectional study of 4030 cases from Turkey by Sabri Aynaci, Sinem Kocagil, Efsun Tosumoglu, Ezgi Susam, Betul Kilic, Ebru Erzurumluoglu Gokalp, Oguz Cilingir, Beyhan Durak Aras, Basar Tekin, Sevilhan Artan

“…Among the detected 130 structural chromosome abnormalities, reciprocal translocations (86 cases, 66.2%) were most frequently observed, followed by Robertsonian translocations in 26 cases (20.0%), inversion in 11 cases (8.5%), marker chromosome in 5 cases (3.8%), and derivative chromosomes in 2 cases (1.5%). …”
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Influence of the extent of cervical lymph node dissection and lymph nodes metastases on prognosis in a cohort of dogs with oral malignant melanoma treated by surgical resection and... by Davide Giacobino, Matteo Olimpo, Erica Ilaria Ferraris, Greta Martinelli, Lorella Maniscalco, Mariateresa Camerino, Federica Riccardo, Federica Cavallo, Lidia Tarone, Marzia Cino, Alfredo Dentini, Selina Iussich, Elena Lardone, Luca Manassero, Raffaella De Maria, Paolo Buracco, Emanuela Morello

“…The most appropriate approach to regional/sentinel lymph nodes (LN) for staging canine oral malignant melanoma (OMM) is still controversial. …”
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Entre espaces domestiques et « espaces domestiqués » : « L’autonomisation intime » des étudiantes en Turquie by Tuğba Gökduman

“…It draws from a sociological survey conducted between 2018-2020 among young women living in Istanbul without their families. These women, most of them being heterosexual and aged between 20-25, were mainly issued from middle-class families from different towns and villages in Turkey. …”
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Oyster mushroom fermented Vachellia erioloba pods as replacement for wheat bran in broiler diets: Physiology and meat physicochemical and nutritional quality by Phethile E. Mabuza, Makiwa S. Mthana, Doctor M.N. Mthiyane

“…Whilst there were no effects of diet on overall body weight gain (BWG), feed conversion efficiency (FCE), mortality rate, carcass traits, meat physicochemical quality, and most haemato-biochemistry parameters (P > 0.05), dietary OMSS increased chicken overall feed intake (FI) (linear: P = 0.043), gizzard weights (linear: P = 0.021), and breast meat ether extract (EE) (linear: P < 0.001) as it tended to increase its ash (P = 0.064) contents. …”
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Improving Leaf GOGAT Activity After the Post-Silking Period Contributes to High Grain Yield with Reduced Nitrogen in N-Efficient Maize by Haoyu Li, Yanbing Wang, Jian Wang, Meng Zhang, Wenbo Liu, Xiangling Li, Xiaohu Lin

“…We also explored the key enzymes and genes related to the N transport amount and efficiency in leaves in the two maize varieties, and found that GOGAT was the key enzyme and <i>GOGAT2</i> was the key gene for JNK728, whereas the AS enzyme and <i>AS1</i> and <i>AS3</i> genes were most important for XY335. Therefore, we suggest that molecular breeding programs should focus on the <i>GOGAT2</i> gene in low-N-efficient maize varieties, and cultivation techniques should aim to improve the GOGAT enzyme activity after the post-silking period to achieve high yields and N utilization efficiencies with less N fertilizer.…”
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Conglomerated Imiquimod and Metronidazole Incorporated Biodegradable Nanofibrous Mats for Potential Therapy of Cervical Cancer by Chen YP, Chiu CF, Wang CN, Lin CC, Shen CR, Yao YC, Kuo YH, Liu SJ

“…Yi-Pin Chen,1,2 Chiao-Fan Chiu,3,4 Chien-Neng Wang,1 Chu-Chi Lin,1 Chia-Rui Shen,5– 7 Yi-Chen Yao,8 Yi-Hua Kuo,8 Shih-Jung Liu8,9 1Department of Obstetrics and Gynecology, Keelung Chang Gung Memorial Hospital, Keelung, 20401, Taiwan; 2School of Traditional Chinese Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan; 3Department of Pediatrics, Linkou Medical Center, Chang Gung Memorial Hospital, Taoyuan, 333, Taiwan; 4Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan, 33302, Taiwan; 5Department of Medical Biotechnology and Laboratory Science, Chang Gung University, Taoyuan, 33302, Taiwan; 6Department of Ophthalmology, Lin-Kou Chang Gung Memorial Hospital, Taoyuan, Taiwan; 7R&D Center of Biochemical Engineering Technology, Department of Chemical Engineering, Ming Chi University of Technology, New Taipei, Taiwan; 8Department of Mechanical Engineering, Chang Gung University, Taoyuan, 33302, Taiwan; 9Bone and Joint Research Center, Department of Orthopedic Surgery, Chang Gung Memorial Hospital-Linkou, Taoyuan, 33305, TaiwanCorrespondence: Shih-Jung Liu, Department of Mechanical Engineering, Chang Gung University, 259, Wen-Hwa 1st Road, Kwei-Shan, Tao-Yuan, 33302, Taiwan, Tel +886-3-2118166, Fax +886-3-2118558, Email shihjung@mail.cgu.edu.twBackground: In clinical practice, imiquimod is used to treat Human Papillomavirus (HPV)-related lesions, such as condyloma and Cervical Intraepithelial Neoplasia (CIN). Metronidazole is the most commonly prescribed antibiotic for bacterial vaginosis. …”
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Elevated serum IL-10/IL-6 ratio as a novel biomarker for secondary central nervous system lymphoma and poor prognosis in DLBCL by Jingjing Wen, Xingyu Nie, Qiaolin Zhou, Yiping Liu, Jing Yue, Ya Zhang, Jing Su, Xiaogong Liang, Fang Xu

“…IntroductionDiffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma and carries a poor prognosis when it involves the central nervous system (CNS), a condition known as secondary CNS lymphoma (SCNSL). …”
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An Inducible CYP19A1 Excision Model for Sexual Differentiation in Chicken (<i>Gallus gallus</i>) via the CRISPR/Cas9 System by Guangzheng Liu, Yixiu Peng, Zeyu Li, Xilin Zhu, Hongyan Sun, Guohong Chen, Qisheng Zuo, Yingjie Niu, Jiuzhou Song, Wei Han, Wanhong Wei, Bichun Li, Kai Jin

“…This study aimed to establish an inducible knockout model of the chicken <i>CYP19A1</i> gene, which encodes aromatase, to support gender control in chickens. We selected the most efficient sgRNA target site and constructed an inducible knockout model based on the Tet-on system. …”
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Carbon Dots Extracted from the Plant <i>Gardenia jasminoides</i> Ameliorates Ischemia–Reperfusion Injury by Liyang Dong, Haojia Zhang, Kai Wang, Chunyu Wang, Yiping Wu, Wei Shao, Kunjing Liu, Xin Lan, Jinhua Han, Jialin Cheng, Changxiang Li, Xueqian Wang, Fafeng Cheng, Qingguo Wang

“…<b>Background:</b> Ischemic stroke (IS) is probably the most important acute serious illness, where interdisciplinary approach is essential to offer the best chance for survival and functional recovery of patients. …”
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Efficacy and tolerability of vortioxetine monotherapy in SSRI-resistant OCD: a retrospective multicenter study by Vassilis Martiadis, Enrico Pessina, Carlo Ignazio Cattaneo, Azzurra Martini, Fabiola Raffone, Tiziano Prodi, Miriam Olivola, Domenico De Berardis, Beatrice Benatti, Beatrice Benatti, Bernardo Maria Dell’Osso, Bernardo Maria Dell’Osso, Bernardo Maria Dell’Osso, Bernardo Maria Dell’Osso

“…The treatment was well tolerated, with nausea (29.7%) and sedation (18.8%) being the most common side effects; no serious adverse events occurred.ConclusionThis study provides preliminary evidence of the efficacy and tolerability of vortioxetine monotherapy in SSRI-resistant OCD. …”
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PREDICTORS OF AGGRESSIVE DIFFERENTIATED THYROID CANCER. A REPORT OF A CASE OF PAPILLARY THYROID CANCER by R. A. Murashko, A. S. Shatokhina, A. I. Stukan, D. V. Andreev, E. V. Dulina

“…There is a need to find new targets for the development of novel drugs for these patients.Conclusion. The most aggressive forms of PTC include diffuse sclerosing, tall cell, and insular variants of PTC. …”
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Cardiorenal disturbances in perimenopausal women by S. N. Tolstov, V. B. Mychka, I. A. Salov, Yu. V. Prokhorova, V. A. Vyshivanyuk

“…At the end of the study, after 12 months, the assessment of metabolic status, body mass dynamics, endothelial vasoregulatory function, and CCA IMT was repeated. Results. In most postmenopausal women, lipid and carbohydrate metabolism disturbances were observed, which were typical for metabolic syndrome (MS). …”
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Prevalence of Psychiatric and Addictive Disorders in Patients with Psoriasis: A Cross-Sectional Study by Daciana Elena Brănișteanu, Roxana Paraschiva Ciobanu, Daniel Constantin Branisteanu, Cristina Colac-Boțoc, Antonia-Elena Huțanu, Cătălina-Anca Munteanu, Rares Stamate, George Brănișteanu, Catalina Ioana Onu-Branisteanu, Mihaela Paula Toader, Elena Porumb-Andrese

“…<b data-eusoft-scrollable-element="1">Results:</b> Of 316 participants, 88 (27.8%) had psychiatric/behavioral comorbidities. The most frequent conditions were tobacco use disorder (11.1% overall; 39.8% among comorbid patients), alcohol use disorder (9.2%; 32.9%), binge eating (7.9%; 28.4%), anxiety (6.3%; 22.7%), and depression (4.1%; 14.8%). …”
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Construction of a prediction model for sarcopenic obesity based on machine learning by Mengru Xu, Mengru Xu, Jia Liu, Jia Liu, Song Hu, Song Hu, Tongxiao Luan, Tongxiao Luan, Yuting Duan, Yuting Duan, Aohua Wang, Aohua Wang, Ziwei Cui, Ziwei Cui, Jing Zhou, Yongjun Mao, Yongjun Mao

“…To develop a predictive model for SO, we used five models and applied internal five-fold cross-validation to determine the most suitable hyperparameters for the model.ResultsAmong 386 participants, 61 were diagnosed with sarcopenic obesity (15.8%). …”
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Molecular genetic diagnosis and surgical management in a cohort of children with 46,XY disorders/differences of sex development by Yuenshan Sammi Wong, Yuenshan Sammi Wong, Ho Ming Luk, Ho Chung Yau, Lap Ming Wong, Sarah Wing Yiu Poon, Joanna Yuet Ling Tung, Yuk Him Tam, Yuk Him Tam

“…ObjectiveA firm diagnosis revealing the etiology of disorders/differences of sex development (DSD) is most helpful in guiding clinical management. The aim of this study is to investigate molecular genetic diagnoses and surgical treatment in a cohort of children with 46,XY DSD.MethodsA retrospective study was conducted on children with 46,XY DSD. …”
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Metagenomic next-generation sequencing-based characterization of the viral spectrum in clinical pulmonary and peripheral blood samples of patients by Ning Zheng, Hai-Long Yu, Bing-Jie Zhang, Dan Wang, Ya-Liang Ji, Lu-Lu Dai, Wen Li, Sheng-Hui Li, Zhi-Liang Hu, Zhi-Liang Hu, Yi-Shan Zheng

“…Bacteriophages dominated all groups, with Siphoviridae and Myoviridae as the most abundant families, although only 13.6% of viral abundance could be assigned to known families. …”
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Design, synthesis, structural characterization, in vitro anticancer activity, and in silico studies of some new hydroxylated and fluorinated-substituted hydrazone derivatives by Reşit Çakmak, Eyüp Başaran, Ömer Erdoğan, Suraj N. Mali, Semiha Köprü, Haya Yasin, Shailesh S. Gurav, Giray Topal

“…Compounds 2a, 3a, 3b, and 3c showed high gastrointestinal (GI) absorption, with all except 3a being non-permeable to the blood-brain barrier (BBB). Most compounds, except 3d, are non-substrates of P-glycoprotein (P-gp). …”
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