Bjerkandera adusta TM11 for the bioremediation of fluoroquinolone antibiotics spiked in wastewater: A sustainable approach to pharmaceutical contaminant biotransformation by Hasna Befenzi, Amine Ezzariai, Jihane Baghor, Hamza Arrach, Jean Armengaud, Mélodie Kielbasa, Annick Doan, Julien Lambert, Anne Lomascolo, Quentin Albert, Craig B. Faulds, Giuliano Sciara, Tahar Mechichi, Lamfeddal Kouisni, Mohamed Hafidi, Loubna El Fels, Eric Record

“…Versatile peroxidase was the most strongly-produced enzyme potentially involved in antibiotic biotransformation. …”
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Methods of induction of labor in women with obesity: A secondary analysis of two multicenter randomized controlled trials by Dorothée M. R. Croll, Marieke D. T. De Vaan, Shinta L. Moes, Kitty W. M. Bloemenkamp, Mieke L. G. Ten Eikelder, Roel De Heus, Marta Jozwiak, Judith Kooiman, Ben Willem Mol, Corine J. M. Verhoeven, Marjon A. De Boer

“…The aim of this study is to assess which method of induction of labor is safest and most effective in women with obesity. Material and methods This is a secondary analysis of two randomized controlled trials about induction of labor. …”
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Treatment with Upadacitinib in Difficult-to-Treat (D2T) Psoriatic Arthritis (PsA): A National Multicenter Study of the First 134 Patients in Clinical Practice by Eva Galíndez-Agirregoikoa, Diana Prieto-Peña, Maria Luz García-Vivar, Joaquin Maria Belzunegui Otano, Beatriz Joven-Ibáñez, Cristina Vergara-Dangond, Marina Pavía-Pascual, Irati Urionaguena-Onaindia, Lucia Vega Alvarez, M. Ángeles Puche Larrubia, Consuelo Ramos Giráldez, Rosario Garcia-Vicuña, Vega Jovani, Angels Martínez-Ferrer, Mireia Moreno Martínez-Losa, Teresa González Hernández, Raquel Almodóvar González, Ana Urruticoechea-Arana, Cristina Macía-Villa, Inigo Gorostiza, Ricardo Blanco Alonso, Upadacitinib PsA Clinical Practice COLLABORATIVE STUDY GROUP

“…This observational, multicenter, open-label study evaluated the efficacy and safety of upadacitinib in 134 patients with psoriatic arthritis (97 women, mean age 51.8 ± 11.2 years, mean disease duration 9.94 ± 7.72 years) who showed inadequate response to advanced therapies. Most patients (74.6%) had received at least two biological/targeted synthetic disease-modifying antirheumatic drugs with different mechanisms of action. …”
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LGR6 modulates intervertebral disc degeneration through regulation of macrophage efferocytosis by Fudong Li, Yangyang Shi, Jun Chen, Jingchuan Sun, Jiangang Shi, Kaiqiang Sun, Bing Zheng

“…Of those genes, LGR6 appeared to be the gene most closely related to IVDD severity. In addition, the mRNA level and protein level of LGR6 in macrophages co-cultured with IL-1β-treated NPCs were raised significantly, compared to the control group. …”
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The Effect of Intravenous Autologous Activated Platelet-Rich Plasma Therapy on “Profibrotic Cytokine” IL-1β Levels in Severe and Critical COVID-19 Patients: A Preliminary Study... by Karina Karina, Louis Martin Christoffel, Rita Novariani, Imam Rosadi, Iis Rosliana, Siti Rosidah, Siti Sobariah, Novy Fatkhurohman, Nurlaela Puspitaningrum, Yuli Hertati, Irsyah Afini, Difky Ernanda, Tias Widyastuti, A. D. Sulaeha, Alfida Zakiyah, Noor Aini, Grady Krisandi, Hubert Andrew

“…Among the cytokines, interleukin-1β (IL-1β) is one of the most overexpressed in COVID-19. We speculate that administration of intravenous activated autologous platelet-rich plasma (aaPRP), which contains interleukin-1 receptor antagonist (IL-1RA), would lower IL-1β levels and benefit the severe and critical COVID-19 patients. …”
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The Application of Barokah herb and salinity on the growth of Sangkuriang catfish Clarias gariepinus Burchell, 1822 by Arum Fahmi Faulana, Zuliyati Rohmah

“… The demand and need for catfish is increasing along with the growth of the Indonesian population, thus requiring greater catfish production. In addition, most of the brackish water areas in Indonesia have not been optimized for freshwater fish farming. …”
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4-1BB and optimized CD28 co-stimulation enhances function of human mono-specific and bi-specific third-generation CAR T cells by Frederick L Locke, Yannick Bulliard, Bin Yu, Marco L Davila, Emiliano Roselli, Justin C Boucher, Gongbo Li, Hiroshi Kotani, Kristen Spitler, Kayla Reid, Estelle V Cervantes, Nhan Tu, Sae Bom Lee

“…Background Co-stimulatory signals regulate the expansion, persistence, and function of chimeric antigen receptor (CAR) T cells. Most studies have focused on the co-stimulatory domains CD28 or 4-1BB. …”
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Risk prediction for recurrent pregnancy loss based on routine inspections in the first trimester of pregnancy, a retrospective study in China by Jinming Wang, Dan Li, Yang Yeung, Zhenglong Guo, Hongke Huang, Li Wang, Weili Shi, Jianmei Huang, Wenke Yang, Yanxin Ren, Shixiu Liao, Yibin Hao

“…BackgroundRecurrent pregnancy loss (RPL) is one of the most common pregnancy complications in obstetrics and gynecology, and the incidence rate of RPL is about 2%. …”
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Multicenter research of the dependence of skin graft engraftment and the concentration of blood hemoglobin, total serum protein and albumin by D. O. Vagner, E. V. Zinoviev, V. V. Soloshenko, A. E. Chukharev, V. S. Borisov, M. Yu. Kaplunova, S. B. Bogdanov, A. A. Petrov, N. V. Ostrovsky, E. P. Malyshina, R. D. Ermolova, D. V. Cherdancev, I. V. Vladimirov

“…This relationship was most pronounced during skin grafting on granulating wounds and after radical necretomy. …”
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A Novel ceRNA Axis LOC121818100/Novel‐miR‐400/SSRP1 Regulated Muscle Growth and Injury Repair in Sheep by Fan Yang, Runqing Chi, Runan Zhang, Kai Liu, Pingqing Wang, Ran Di, Xiaoyun He, Xiangyu Wang, Yufang Liu, Mingxing Chu

“…Bioinformatics analysis showed that LOC121818100/Novel‐miR‐400/SSRP1 was most correlated with skeletal muscle development (p < 0.05). …”
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Pharmacological potential of 6,11-dihydro[1,2,4]triazolo[4’,3’:1,6]-pyrido[3,4-b]-5-carboxylic acid and its esters by S. O. Fedotov, A. S. Hotsulia

“…Molecular docking was performed using Vina software, which provides modelling and evaluation of interactions between ligand and three-dimensional protein structure, considering their energy and spatial compatibility. Results. The most favourable safety profile of in silico studies has been shown by 6,11-dihydro[1,2,4]triazolo[4’,3’:1,6]pyrido[3,4-b]-5-carboxylic acid. …”
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PO45 | Routine prophylaxis with PD-FX concentrate in severe inherited FX deficiency: a case report

“…One hundred eighty mutations, most of which missense, have been identified to date. …”
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Behavioral and biochemical changes associated with the analgesic effects of (2R,6R)-hydroxynorketamine alone and in combination with meloxicam following disk puncture in mice by Vaskar Das, Isabella Milejczyk, Michael B. Basovich, Mario Moric, Jay Kaila, Craig J. Thomas, Asokumar Buvanendran, Robert J. McCarthy

“…IntroductionLow back pain affects around 619 million people globally and is the most prevalent musculoskeletal condition worldwide. …”
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Longitudinal characterization of plasma and fecal bile acids in dairy heifers from birth to first calving in response to transition milk feeding by M.H. Ghaffari, C.S. Ostendorf, K.J. Hemmert, S. Schuchardt, C. Koch, H. Sauerwein

“…Fecal bile acid profiles in TM-fed calves clustered distinctly at birth, evolving through pre- to postweaning and calving, with increasing profile overlap over time. Most fecal bile acids, except DCA and CA, were abundant at birth but declined over time. …”
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Rhodium-based metallodrugs for biological applications: current status and future perspectives by Wang Xiang, Suisui He, Tao Kuang, Jun Yin, Bin Hu, Chao Sun, Juan He, Jun Wang, Cui-Yun Yu, Hua Wei

“…Metal complexes represent a promising avenue in drug research and development, exemplified by metallodrugs including cisplatin, carboplatin, and oxaliplatin that have been clinically approved for the treatment of various solid tumors. However, most of the reported metallodrugs suffer from compromised therapeutic efficacy due to multidrug resistance (MDR) and severe systemic toxicity. …”
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Atypical symptoms and delayed diagnosis are more common in elderly patients with benign paroxysmal positional vertigo: a single-center study by Hongyan Li, Hongyan Li, Yanping Tong, Yan Wang, Yan Wang, Meimei Chen, Meimei Chen, Yu Cui, Yu Cui, Xiaolin Wu, Xiaolin Wu, Yi Ju, Yi Ju

“…The posterior semicircular canal was the most commonly affected site (62.3%) in elderly patients, and the incidence of horizontal semicircular canal canalolithiasis was higher in the elderly group compared to the young-to-middle-aged group (16.2% vs. 13.6%, p &lt; 0.001). …”
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Efficacy of Xiaoyao-san preparations in treating Hashimoto’s thyroiditis: a meta-analysis and systematic review by Chengna Wang, Chengna Wang, Wenxin Ma, Lingling Qin, Lingling Qin, Lili Wu, Tonghua Liu

“…While XYSJW outperforms OS preparations in lowering TgAb levels, it may not surpass OS in restoring thyroid hormone levels. Most studies reviewed are of low quality. XYS preparations appear to modulate cytokines by targeting immune markers and reducing inflammation, but their safety profile remains unclear, requiring further robust evidence.Systematic Review Registrationclinicaltrials.gov, identifier CRD42023472233.…”
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Seasonal Changes in Performance Metrics, Hormonal, Hematological, and Biochemical Markers Among Semi-Professional Soccer Players: Implications for Training and Recovery by Eleftherios Mylonis, Dimitrios I. Bourdas, Natalia Kompodieta, Athanasios Tegousis, Panteleimon Bakirtzoglou, Athanasios Souglis, Evangelos Bekris

“…Stability in lower limb strength, flexibility, triglycerides, C-reactive protein, ferritin, liver enzymes, and most hematological parameters suggest resilience to seasonal demands. …”
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Access to rehabilitation after stroke in Brazil (AReA study): multicenter study protocol by Roberta de Oliveira Cacho, Carla Heloisa Cabral Moro, Rodrigo Bazan, Suzete Nascimento Farias da Guarda, Elen Beatriz Pinto, Suellen Mary Marinho dos Santos Andrade, Lenise Valler, Kelson James Almeida, Tatiana Souza Ribeiro, Renata Viana Brígido de Moura Jucá, Cesar Minelli, Maria Elisa Pimentel Piemonte, Eric Homero Albuquerque Paschoal, Marco Túlio Araújo Pedatella, Octávio Marques Pontes-Neto, Ana Paula Fontana, Aline de Souza Pagnussat, Adriana Bastos Conforto

“…Background Most of the Brazilian population relies on public healthcare and stroke is a major cause of disability in this country of continental dimensions. …”
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The Impact of Stellar Rotations and Binaries on the Shape of Upper Main Sequence near Turnoff in Open Cluster NGC 6067 by Jayanand Maurya, Yu Zhang, Sebastian Kamann, Hubiao Niu, Yves Frémat, Kaixiang Lang, Y. C. Joshi, M. R. Samal, Peter De Cat, Ali Esamdin

“…The gravity-darkening effect might be a reason for this correlation. We find that most of the close binaries present in the eMSTO population would be slow-rotating due to the tidal-locking phenomenon. …”
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