KATALIKŲ BAŽNYČIOS KAITA LIETUVOJE TRANSFORMACIJŲ LAIKOTARPIU by Valdas Pruskus

“…CHANGES OF CATHOLIC CHURCH IN LITHUANIA IN TIME OF TRANSFORMATIONS Valdas Pruskus Summay After the restoration of independence of Lithuania, changing of Catholic Church as an institution was predetermined by two most important factors. One of them was the heritage of the anti-church policy promoted in the Soviet times. …”
Get full text

Chinese SLE Treatment and Research Group Registry: III. Association of Autoantibodies with Clinical Manifestations in Chinese Patients with Systemic Lupus Erythematosus by Jing Li, Xiaomei Leng, Zhijun Li, Zhizhong Ye, Caifeng Li, Xiaofeng Li, Ping Zhu, Zhengang Wang, Yi Zheng, Xiangpei Li, Miaojia Zhang, Xin-Ping Tian, Mengtao Li, Jiuliang Zhao, Feng-Chun Zhang, Yan Zhao, Xiaofeng Zeng

“…Associations were also found between anti-dsDNA antibody and a lower prevalence of photosensitivity, and between anti-SSA antibody and a lower prevalence of nephropathy (P<0.05). Most of these findings were consistent with other studies in the literature but this study is the first report on the association between anti-SSA and a lower prevalence of nephropathy. …”
Get full text

A preoperative pathological staging prediction model for esophageal cancer based on CT radiomics by Haojun Li, Shuoming Liang, Mengxuan Cui, Weiqiu Jin, Xiaofeng Jiang, Simiao Lu, Jicheng Xiong, Hainan Chen, Ziwei Wang, Guotai Wang, Jiming Xu, Linfeng Li, Yao Wang, Haomiao Qing, Yongtao Han, Xuefeng Leng

“…Abstract Background Accurate and comprehensive preoperative staging is one of the most important prognostic factors for the management of esophageal cancer (EC). …”
Get full text

Agricultural waste byproduct utilization: Date pit powder 1H NMR metabolite identification for goat (Capra hircus) milk pathway analysis by M.R.Abd Rahman, M.M. Aween, Z. Hassan, M.S. Hassan, R. Hashim, I.S. Ismail, M.S.M. Misenan, R. Ranjithkumar, K.F. Li, L.S. Wong

“…The 1H NMR data of DPP samples from TCA and PB extracts (non-polar) successfully eliminated most metabolites in comparison to the aqueous ACN and MeOH extracts (polar). …”
Get full text

Assessment of Knowledge Attitude and Practices of Rural Population Towards Infectious Diseases and Their Prevention by Saumya Shukla1, Kumar S Abhishek2, Laxmi Rathore3, Vinod Kumar Maurya1*, Vandana Upadhyay1, Pawan Kumar Dubey4, Amit Kumar Singh1

“…A majority of participants (58.8%) had attained or were pursuing college-level education or higher. Most respondents (84.2%) lacked knowledge of endemic diseases, and 82% lacked knowledge of vaccine-preventable diseases in the study region. …”
Get full text

Multifactorial Risk Stratification in Patients with Heart Failure, Chronic Kidney Disease, and Atrial Fibrillation: A Comprehensive Analysis by Mihai Sorin Iacob, Nilima Rajpal Kundnani, Abhinav Sharma, Vlad Meche, Paul Ciobotaru, Ovidiu Bedreag, Dorel Sandesc, Simona Ruxanda Dragan, Marius Papurica, Livia Claudia Stanga

“…Statistical analysis included Spearman correlation, independent t-tests, and multivariate regression to evaluate associations between variables and clinical outcomes. <b>Results:</b> Most patients were elderly (mean age 75 ± 12), with advanced CKD (stage 3b) and systolic HF (77% HFrEF). …”
Get full text

MiR-3664-3p through suppressing ABCG2, CYP3A4, MCL1, and MLH1 increases the sensitivity of colorectal cancer cells to irinotecan by Elham Farrokhnazar, Sahar Moghbelinejad, Reza Najafipour, Ladan Teimoori-Toolabi

“…Background: Colorectal cancer (CRC) is the third most frequently diagnosed malignancy worldwide. Currently, irinotecan (CPT-11) is used alone or in combination with other drugs to treat patients with advanced CRC. …”
Get full text

Retinal ganglion cell repopulation for vision restoration in optic neuropathy: a roadmap from the RReSTORe Consortium by Jonathan R. Soucy, Erika A. Aguzzi, Julie Cho, Michael James Gilhooley, Casey Keuthan, Ziming Luo, Aboozar Monavarfeshani, Meher A. Saleem, Xue-Wei Wang, Juilette Wohlschlegel, The RReSTORe Consortium, Petr Baranov, Adriana Di Polo, Brad Fortune, Kimberly K. Gokoffski, Jeffrey L. Goldberg, William Guido, Alex L. Kolodkin, Carol A. Mason, Yvonne Ou, Thomas A. Reh, Ahmara G. Ross, Brian C. Samuels, Derek Welsbie, Donald J. Zack, Thomas V. Johnson

“…In 2022, the RReSTORe Consortium initiated ongoing international collaborative discussions to advance the RGC repopulation field and has identified five critical areas of focus: (1) RGC development and differentiation, (2) Transplantation methods and models, (3) RGC survival, maturation, and host interactions, (4) Inner retinal wiring, and (5) Eye-to-brain connectivity. Here, we discuss the most pertinent questions and challenges that exist on the path to clinical translation and suggest experimental directions to propel this work going forward. …”
Get full text

Establishing a long-term predictive model for aggressive behavior in schizophrenia: a 21-year longitudinal study in rural China by Hui Jin, Hui Jin, Cong Wang, Cong Wang, Yi-Yue Yang, Yi-Yue Yang, Lie Zhou, Lie Zhou, Yun Xiao, Yun Xiao, Yang Wen, Yang Wen, Jawad Ahmad, Jawad Ahmad, Yun-Fei Mu, Yun-Fei Mu, Jia Cai, Ming Li, Wei Luo, Xiao-Fei Zhou, Jian-Jun Luo, Bo Liu, Eric Yu-Hai Chen, Mao-Sheng Ran, Mao-Sheng Ran

“…BackgroundAlthough identifying factors contributing to aggressive behavior in individuals with schizophrenia is crucial for developing targeted prevention strategies and intervention, most studies were cross-sectional or short-term, and did not take into account the factor of urbanicity. …”
Get full text

Peroxisome proliferator‐activated receptor gamma (PPARγ) is central to the initiation and propagation of human angiomyolipoma, suggesting its potential as a therapeutic target by Oren Pleniceanu, Racheli Shukrun, Dorit Omer, Einav Vax, Itamar Kanter, Klaudyna Dziedzic, Naomi Pode‐Shakked, Michal Mark‐Daniei, Sara Pri‐Chen, Yehudit Gnatek, Hadas Alfandary, Nira Varda‐Bloom, Dekel D Bar‐Lev, Naomi Bollag, Rachel Shtainfeld, Leah Armon, Achia Urbach, Tomer Kalisky, Arnon Nagler, Orit Harari‐Steinberg, Jack L Arbiser, Benjamin Dekel

“…Abstract Angiomyolipoma (AML), the most common benign renal tumor, can result in severe morbidity from hemorrhage and renal failure. …”
Get full text

Global catalog of soil moisture droughts over the past four decades by J. Řehoř, J. Řehoř, R. Brázdil, R. Brázdil, O. Rakovec, O. Rakovec, M. Hanel, M. Fischer, M. Fischer, R. Kumar, J. Balek, J. Balek, M. Poděbradská, M. Poděbradská, V. Moravec, V. Moravec, L. Samaniego, L. Samaniego, Y. Markonis, M. Trnka, M. Trnka

“…Our global-scale synthesis revealed the highest relative proportions of extremely severe and extremely dynamic GLDEs in the South American region, followed by North America, while the longest and most extensive single GLDEs occurred in Eurasia. …”
Get full text

Association Between Neighborhood-Level Social Vulnerability and Hypertension Outcomes by John E. Brush, Jr., MD, Chungsoo Kim, PharmD, PhD, Yuntian Liu, MPH, Xin Xin, MS, Chenxi Huang, PhD, Iris J. Lundy, BSN, Jordan R. Asher, MD, MS, Mitsuaki Sawano, MD, Patrick Young, PhD, Jacob McPadden, MD, Mark Anderson, AS, John S. Burrows, MBA, Harlan M. Krumholz, MD, SM, Yuan Lu, ScD

“…Results: In a longitudinal cohort of 330,972 patients with hypertension followed for a median of 6.6 years, the neighborhood-level SVI was significantly associated with the composite endpoint after adjustment for demographics, baseline body mass index and blood pressure (BP), and comorbidities (HR for quartile 4 [most disadvantaged group] vs quartile 1 = 1.31 [95% CI: 1.25-1.38], P < 0.001). …”
Get full text

Exploring effector-host interactions in Pyricularia oryzae infections: A molecular and structural approach to rice blast resistance by Zakir Amin, F.A. Mohiddin, Ali Anwar, Asif B. Shikari, Sajad Un Nabi, Tauseef A. Bhat, Vishal Gupta, Fehim Jeelani Wani, Shugufta Parveen, Mohd Salim Mir, Subaya Manzoor, Suhail Ashraf, Mohammad Raish

“…Rice blast, caused by Pyricularia oryzae, is one of the most destructive diseases affecting global rice production, often leading to severe yield losses and threatening food security. …”
Get full text

Dry-shrinkage of sandy clay improved by ecological fibers based on experiment and DEM simulation by Hong Guo, Yuyan Lu, Wenyang Li, Fang Dang, Ya Wang, Xiaoqin Luo, Jiangtao Fu, Hong Jiang, Mingjiang Tao

“…Notably, at a dosage of 0.6 %, jute fibers and rice straw fibers showed the most significant improvements: reducing crack rates by 30.6 % and 23.8 %, respectively, and average crack widths by 66.64 % and 70.86 %, respectively. …”
Get full text

Rainfall as an important process for net N gain during the initial phase of natural recovery in karst desertification by Xia Li, Yu Pang, Hengsheng Lao, Linfang Luo, Tongxin He, Guangting Pei, Shuangshuang Xiao, Baoqing Hu, Jianfei Sun

“…The mean rainfall net N gain was 3.4 kg N ha−1 y−1, and inorganic N contributed vastly to net N gain, while DON was a net loss. Most rainfall inorganic N was retained by the soil, while DON loss was mainly derived from soil, indicating N exchange between rainfall and soil during the hydrologic process. …”
Get full text

COVID-19 patient variables associated with the detection of airborne SARS-CoV-2 by Joan Truyols-Vives, Gabriel Escarrer-Garau, Laura Arbona-González, Núria Toledo-Pons, Jaume Sauleda-Roig, Miguel David Ferrer, Pablo Arturo Fraile-Ribot, Antonio Doménech-Sánchez, Herme García-Baldoví, Ernest Sala-Llinàs, Antoni Colom-Fernández, Josep Mercader-Barceló

“…No significant associations were found between airborne SARS-CoV-2 detection and symptoms presence or duration, nor with the results of the most recent positive nasopharyngeal PCR test prior to air sampling. …”
Get full text

Gut microbiota influence on lung cancer risk through blood metabolite mediation: from a comprehensive Mendelian randomization analysis and genetic analysis by Yizhao Du, Qin Wang, Zongmei Zheng, Hailun Zhou, Yang Han, Ao Qi, Lijing Jiao, Lijing Jiao, Yabin Gong

“…Metabolic pathway analysis revealed glutathione metabolism and glutamate metabolism are the pathways most enriched with significant metabolites related to LC.ConclusionThese findings underscore the importance of GM in the development of LC, with metabolites partly mediating this effect, and provide dietary and lifestyle recommendations for high-risk lung cancer populations.…”
Get full text

PODO447: a novel antibody to a tumor-restricted epitope on the cancer antigen podocalyxin by Blake Gilks, Martin Köbel, Diana Canals Hernaez, Michael R Hughes, Pamela Dean, Peter Bergqvist, Ismael Samudio, Ola Blixt, Katharina Wiedemeyer, Yicong Li, Chris Bond, Eric Cruz, Calvin D Roskelley, Kelly M McNagny

“…Mapping of the tumor-restricted epitope was performed using enzyme-treated human tumor cell lines and a glycan array.Results One mAb (PODO447) showed strong reactivity with a variety of Podxl+ tumor cell lines but not with normal primary human tissue including Podxl+ kidney podocytes and most vascular endothelia. Screening of an ovarian carcinoma TMA (219 cases) revealed PODO447 reactivity with the majority of tumors, including 65% of the high-grade serous histotype. …”
Get full text

Trends in the epidemiology of chronic kidney disease in patients with diabetes in Russian Federation according to the Federal diabetes register (2010–2022) by M. S. Shamkhalova, O. K. Vikulova, A. V. Zheleznyakova, M. A. Isakov, M. V. Shestakova, I. I. Dedov, N. G. Mokrysheva

“…There is the CKD prognosis calculator in the FRD, which allows assessing the risk of developing of pathology within 5 years in a particular patient based on a set of the most significant predictors, which included 6 factors for T1 and 11 factors for T2. …”
Get full text

Production of ‘Aliança’ papaya seedlings under different dosages and sources of Lithothamnion sp by Elmo Pereira Ramos, Diego Borges de Aguiar, Ana Kelly Mota Barbosa, Vinicius de Souza Oliveira, Vinicius de Souza Oliveira, Lúcio de Oliveira Arantes, Edilson Romais Schmildt, Antelmo Ralph Falqueto, Adriano Alves Fernandes, Sara Dousseau-Arantes, Sara Dousseau-Arantes, Sara Dousseau-Arantes

“…Lithothamnion sp. from the coast of Maranhão (Algen®) and Bahia (Prima®) increased leaf phosphorus and root sulfur levels.DiscussionLithothamnion sp. promoted a biostimulant effect with improved growth and development in ’Aliança‘ papaya seedlings, with a dosage close to 4 kg m-3, with the LT supra® product being the most recommended.…”
Get full text